Kruppel-like factor 4 is a novel mediator of Kallistatin in inhibiting endothelial inflammation via increased endothelial nitric-oxide synthase expression

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Kruppel-like factor 4 is a novel mediator of Kallistatin in inhibiting endothelial inflammation via increased endothelial nitric-oxide synthase expression is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M109.046813
P932PMC publication ID2790976
P698PubMed publication ID19858207

P2093author name stringBo Shen
Yi-Te Hsu
Robert S Smith
Julie Chao
Lee Chao
P2860cites workIdentification and characterization of a gene encoding a gut-enriched Krüppel-like factor expressed during growth arrestQ24311735
Human EZF, a Krüppel-like zinc finger protein, is expressed in vascular endothelial cells and contains transcriptional activation and repression domainsQ24318678
Kallistatin is a potent new vasodilatorQ24561603
Endothelial nitric oxide synthase: a new paradigm for gene regulation in the injured blood vesselQ28189283
Expression of kallikrein-binding protein and alpha 1-antitrypsin genes in response to sex hormones, growth, inflammation and hypertensionQ28570653
Domain mapping studies reveal that the M domain of hsp90 serves as a molecular scaffold to regulate Akt-dependent phosphorylation of endothelial nitric oxide synthase and NO releaseQ28609861
Novel role of kallistatin in protection against myocardial ischemia-reperfusion injury by preventing apoptosis and inflammationQ33262479
The tissue-dependent keratin 19 gene transcription is regulated by GKLF/KLF4 and Sp1.Q33906184
DNA microarray reveals changes in gene expression of shear stressed human umbilical vein endothelial cellsQ33929217
Kallistatin is a new inhibitor of angiogenesis and tumor growthQ34154808
Structural elements of kallistatin required for inhibition of angiogenesisQ34195175
Kallistatin: a novel human serine proteinase inhibitor. Molecular cloning, tissue distribution, and expression in Escherichia coliQ34343869
Kallistatin, a novel human tissue kallikrein inhibitor: levels in body fluids, blood cells, and tissues in health and diseaseQ34382306
Kallistatin in human ocular tissues: reduced levels in vitreous fluids from patients with diabetic retinopathyQ34409943
Identification of a receptor necessary for Nogo-B stimulated chemotaxis and morphogenesis of endothelial cellsQ34984247
Cardiovascular and renal control in NOS-deficient mouse modelsQ35061516
Nitric oxide decreases cytokine-induced endothelial activation. Nitric oxide selectively reduces endothelial expression of adhesion molecules and proinflammatory cytokinesQ35749970
TAK1 is a central mediator of NOD2 signaling in epidermal cellsQ36528456
The dialogue between endothelial cells and monocytes/macrophages in vascular syndromesQ36855661
Nox4 NADPH oxidase mediates oxidative stress and apoptosis caused by TNF-alpha in cerebral vascular endothelial cellsQ37139048
Plasma membrane nucleolin is a receptor for the anticancer aptamer AS1411 in MV4-11 leukemia cellsQ37415807
The nucleolin targeting aptamer AS1411 destabilizes Bcl-2 messenger RNA in human breast cancer cellsQ38292167
Nitric oxide regulates exocytosis by S-nitrosylation of N-ethylmaleimide-sensitive factor.Q39821682
Leukocyte-endothelial adhesion moleculesQ40392834
Nitric oxide, an endothelial cell relaxation factor, inhibits neutrophil superoxide anion production via a direct action on the NADPH oxidaseQ40512506
Identification of a new tissue-kallikrein-binding proteinQ42165219
Increased superoxide generation is associated with pulmonary hypertension in fetal lambs: a role for NADPH oxidaseQ44333254
A central role for inflammation in the pathogenesis of diabetic retinopathyQ44961996
Prophylactic adenovirus-mediated human kallistatin gene therapy suppresses rat arthritis by inhibiting angiogenesis and inflammationQ45882701
Role of kallistatin in prevention of cardiac remodeling after chronic myocardial infarctionQ46397663
Salutary effect of kallistatin in salt-induced renal injury, inflammation, and fibrosis via antioxidative stressQ46662638
TNF-alpha contributes to endothelial dysfunction in ischemia/reperfusion injuryQ46872639
Kruppel-like factor 4 regulates endothelial inflammation.Q55043476
Kallistatin stimulates vascular smooth muscle cell proliferation and migration in vitro and neointima formation in balloon-injured rat arteryQ64380933
Inhibition of endothelial-derived nitric oxide promotes P-selectin expression and actions in the rat microcirculationQ71650202
Inhibition of nitric oxide formation in vivo enhances superoxide release by the perfused liverQ72517519
Alkaline phosphatase fusion proteins for molecular characterization and cloning of receptors and their ligandsQ73110172
Kallikrein-binding protein levels are reduced in the retinas of streptozotocin-induced diabetic ratsQ73157193
Beneficial effects of kallikrein-binding protein in transgenic mice during endotoxic shockQ73287311
Interleukin-13 selectively induces monocyte chemoattractant protein-1 synthesis and secretion by human endothelial cells. Involvement of IL-4R alpha and Stat6 phosphorylationQ73707587
Upregulation of VCAM-1 and ICAM-1 at atherosclerosis-prone sites on the endothelium in the ApoE-deficient mouseQ74582629
Cell surface nucleolin serves as receptor for DNA nanoparticles composed of pegylated polylysine and DNAQ80146633
P433issue51
P407language of work or nameEnglishQ1860
P921main subjectendotheliumQ111140
inflammationQ101991
P304page(s)35471-35478
P577publication date2009-12-01
P1433published inJournal of Biological ChemistryQ867727
P1476titleKruppel-like factor 4 is a novel mediator of Kallistatin in inhibiting endothelial inflammation via increased endothelial nitric-oxide synthase expression
P478volume284

Reverse relations

cites work (P2860)
Q24307913A regulatory role of Kruppel-like factor 4 in endothelial argininosuccinate synthetase 1 expression in response to laminar shear stress
Q36389929Apelin/APJ signaling is a critical regulator of statin effects in vascular endothelial cells--brief report
Q49179977Cell surface expression of nucleolin mediates the antiangiogenic and antitumor activities of kallistatin.
Q38980848Circulating Endothelial Cells Expressing the Angiogenic Transcription Factor Krüppel-Like Factor 4 are Decreased in Patients with Coronary Artery Disease
Q50238802Codon optimization increases human kallistatin expression in Escherichia coli.
Q92409363Endothelial Cell Mechano-Metabolomic Coupling to Disease States in the Lung Microvasculature
Q33787467Hemodynamic disturbed flow induces differential DNA methylation of endothelial Kruppel-Like Factor 4 promoter in vitro and in vivo
Q87170742Human kallistatin administration reduces organ injury and improves survival in a mouse model of polymicrobial sepsis
Q45069805Induction of Krüppel-like factor 4 expression in reactive astrocytes following ischemic injury in vitro and in vivo.
Q38631767KLF4 Regulation of Ch25h and LXR Mitigates Atherosclerosis Susceptibility
Q64103582KLF4 activates NFκB signaling and esophageal epithelial inflammation via the Rho-related GTP-binding protein RHOF
Q33939375Kallistatin antagonizes Wnt/β-catenin signaling and cancer cell motility via binding to low-density lipoprotein receptor-related protein 6
Q34357797Kallistatin attenuates endothelial apoptosis through inhibition of oxidative stress and activation of Akt-eNOS signaling
Q89544590Kallistatin attenuates endothelial senescence by modulating Let-7g-mediated miR-34a-SIRT1-eNOS pathway
Q95260601Kallistatin correlates with inflammation in abdominal aortic aneurysm and suppresses its formation in mice
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Q35654838Kallistatin treatment attenuates lethality and organ injury in mouse models of established sepsis
Q38031130Kruppel-like factors and vascular inflammation: implications for atherosclerosis
Q37054152Krüppel-Like Factor 4 Is a Regulator of Proinflammatory Signaling in Fibroblast-Like Synoviocytes through Increased IL-6 Expression.
Q39151066Krüppel-like factor 4 (KLF4): What we currently know
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Q38383813miR-483 Targeting of CTGF Suppresses Endothelial-to-Mesenchymal Transition: Therapeutic Implications in Kawasaki Disease.

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