| scholarly article | Q13442814 |
| P819 | ADS bibcode | 2009PLoSO...4.7914D |
| P356 | DOI | 10.1371/JOURNAL.PONE.0007914 |
| P932 | PMC publication ID | 2780319 |
| P698 | PubMed publication ID | 19956589 |
| P5875 | ResearchGate publication ID | 40443671 |
| P2093 | author name string | Sanjay I Bidichandani | |
| Yogesh K Chutake | |||
| Irene De Biase | |||
| Paul M Rindler | |||
| P2860 | cites work | High-throughput mapping of the chromatin structure of human promoters. | Q51582234 |
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| The GAA triplet-repeat expansion in Friedreich ataxia interferes with transcription and may be associated with an unusual DNA structure | Q24538667 | ||
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| Expression of the CTCF-paralogous cancer-testis gene, brother of the regulator of imprinted sites (BORIS), is regulated by three alternative promoters modulated by CpG methylation and by CTCF and p53 transcription factors | Q24685814 | ||
| High-resolution profiling of histone methylations in the human genome | Q27860906 | ||
| Insulators: exploiting transcriptional and epigenetic mechanisms | Q28257767 | ||
| Friedreich's ataxia: autosomal recessive disease caused by an intronic GAA triplet repeat expansion | Q28275699 | ||
| The cohesin complex and its roles in chromosome biology | Q28302885 | ||
| Nascent RNA sequencing reveals widespread pausing and divergent initiation at human promoters | Q28302903 | ||
| Divergent transcription from active promoters | Q29614332 | ||
| RNA maps reveal new RNA classes and a possible function for pervasive transcription | Q29614334 | ||
| Heterochromatin revisited | Q29614716 | ||
| Cohesin mediates transcriptional insulation by CCCTC-binding factor | Q29618130 | ||
| Cohesins functionally associate with CTCF on mammalian chromosome arms | Q29618753 | ||
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| Promoter-associated RNA is required for RNA-directed transcriptional gene silencing in human cells | Q34653770 | ||
| A rapid micro chromatin immunoprecipitation assay (microChIP). | Q34785155 | ||
| Friedreich ataxia | Q34851882 | ||
| The antisense transcriptomes of human cells | Q34895481 | ||
| DNA sequence-specific polyamides alleviate transcription inhibition associated with long GAA.TTC repeats in Friedreich's ataxia | Q34984370 | ||
| Real time PCR quantification of frataxin mRNA in the peripheral blood leucocytes of Friedreich ataxia patients and carriers. | Q35481748 | ||
| Independent and complementary methods for large-scale structural analysis of mammalian chromatin | Q35840734 | ||
| Repeat-induced epigenetic changes in intron 1 of the frataxin gene and its consequences in Friedreich ataxia | Q35865338 | ||
| Nucleosome positioning and gene regulation: advances through genomics | Q36883122 | ||
| MicroRNA-directed transcriptional gene silencing in mammalian cells | Q36945167 | ||
| siRNA-mediated heterochromatin establishment requires HP1 and is associated with antisense transcription | Q36954795 | ||
| Genetics and epigenetics of the multifunctional protein CTCF. | Q36976477 | ||
| Boundaries. Boundaries...Boundaries??? | Q37182068 | ||
| Chromatin insulators: regulatory mechanisms and epigenetic inheritance | Q37292727 | ||
| How cohesin and CTCF cooperate in regulating gene expression | Q37421551 | ||
| The LPS-induced transcriptional upregulation of the chicken lysozyme locus involves CTCF eviction and noncoding RNA transcription. | Q38360104 | ||
| The Friedreich ataxia GAA repeat expansion mutation induces comparable epigenetic changes in human and transgenic mouse brain and heart tissues | Q40149163 | ||
| Histone deacetylase inhibitors reverse gene silencing in Friedreich's ataxia. | Q40241487 | ||
| Antisense transcription and heterochromatin at the DM1 CTG repeats are constrained by CTCF. | Q46802333 | ||
| Inhibitory effects of expanded GAA.TTC triplet repeats from intron I of the Friedreich ataxia gene on transcription and replication in vivo | Q48034382 | ||
| P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P433 | issue | 11 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | Friedreich ataxia | Q913856 |
| P304 | page(s) | e7914 | |
| P577 | publication date | 2009-11-19 | |
| P1433 | published in | PLOS One | Q564954 |
| P1476 | title | Epigenetic silencing in Friedreich ataxia is associated with depletion of CTCF (CCCTC-binding factor) and antisense transcription | |
| P478 | volume | 4 |
| Q34940777 | A GAA repeat expansion reporter model of Friedreich's ataxia recapitulates the genomic context and allows rapid screening of therapeutic compounds. |
| Q35144024 | A novel GAA-repeat-expansion-based mouse model of Friedreich's ataxia |
| Q48670933 | Alleviating GAA Repeat Induced Transcriptional Silencing of the Friedreich's Ataxia Gene During Somatic Cell Reprogramming |
| Q34075853 | Altered nucleosome positioning at the transcription start site and deficient transcriptional initiation in Friedreich ataxia |
| Q38121944 | Animal and cellular models of Friedreich ataxia. |
| Q41974951 | Apn1 AP-endonuclease is essential for the repair of oxidatively damaged DNA bases in yeast frataxin-deficient cells. |
| Q35137677 | Base excision repair of chemotherapeutically-induced alkylated DNA damage predominantly causes contractions of expanded GAA repeats associated with Friedreich's ataxia. |
| Q38949804 | CTCF induces histone variant incorporation, erases the H3K27me3 histone mark and opens chromatin |
| Q30502612 | CTCF regulates ataxin-7 expression through promotion of a convergently transcribed, antisense noncoding RNA. |
| Q36016607 | Chromatin changes in the development and pathology of the Fragile X-associated disorders and Friedreich ataxia |
| Q41788602 | Comparative (computational) analysis of the DNA methylation status of trinucleotide repeat expansion diseases. |
| Q38679540 | Compound heterozygous FXN mutations and clinical outcome in friedreich ataxia |
| Q33637169 | Convergent transcription through a long CAG tract destabilizes repeats and induces apoptosis |
| Q92488515 | Dimethyl fumarate dosing in humans increases frataxin expression: A potential therapy for Friedreich's Ataxia |
| Q30602174 | Dyclonine rescues frataxin deficiency in animal models and buccal cells of patients with Friedreich's ataxia |
| Q34418695 | Epigenetic and neurological effects and safety of high-dose nicotinamide in patients with Friedreich's ataxia: an exploratory, open-label, dose-escalation study. |
| Q37695480 | Epigenetic changes and non-coding expanded repeats |
| Q38219414 | Epigenetic-based therapies for Friedreich ataxia |
| Q26770705 | Epigenetics and Triplet-Repeat Neurological Diseases |
| Q36663928 | Epigenetics in Friedreich's Ataxia: Challenges and Opportunities for Therapy |
| Q54765415 | Epigenetics, fragile X syndrome and transcriptional therapy. |
| Q27301037 | Expanded GAA repeats impair FXN gene expression and reposition the FXN locus to the nuclear lamina in single cells |
| Q36302082 | Expanded GAA repeats impede transcription elongation through the FXN gene and induce transcriptional silencing that is restricted to the FXN locus |
| Q38066802 | Expanded complexity of unstable repeat diseases. |
| Q59328859 | FAST-1 antisense RNA epigenetically alters FXN expression |
| Q47872898 | FXN methylation predicts expression and clinical outcome in Friedreich ataxia. |
| Q34984786 | Friedreich ataxia patient tissues exhibit increased 5-hydroxymethylcytosine modification and decreased CTCF binding at the FXN locus |
| Q34330367 | Friedreich's ataxia induced pluripotent stem cells model intergenerational GAA⋅TTC triplet repeat instability |
| Q38160224 | Friedreich's ataxia, frataxin, PIP5K1B: echo of a distant fracas. |
| Q36088803 | Friedreich's ataxia--a case of aberrant transcription termination? |
| Q38121941 | Gene regulation and epigenetics in Friedreich's ataxia |
| Q28540063 | Generation and characterisation of Friedreich ataxia YG8R mouse fibroblast and neural stem cell models |
| Q40068916 | Genome-wide screen identifies pathways that govern GAA/TTC repeat fragility and expansions in dividing and nondividing yeast cells. |
| Q37723199 | Heterochromatin dysregulation in human diseases |
| Q24634126 | Hyperexpansion of GAA repeats affects post-initiation steps of FXN transcription in Friedreich's ataxia |
| Q55394024 | Increased Frataxin Expression Induced in Friedreich Ataxia Cells by Platinum TALE-VP64s or Platinum TALE-SunTag. |
| Q37155503 | Increasing frataxin gene expression with histone deacetylase inhibitors as a therapeutic approach for Friedreich's ataxia. |
| Q35833870 | Is Friedreich ataxia an epigenetic disorder? |
| Q33961697 | Long range regulation of human FXN gene expression |
| Q35149824 | Mechanism of Action of 2-Aminobenzamide HDAC Inhibitors in Reversing Gene Silencing in Friedreich's Ataxia. |
| Q36818189 | Novel antioxidants protect mitochondria from the effects of oligomeric amyloid beta and contribute to the maintenance of epigenome function |
| Q34442152 | Nucleotide excision repair, mismatch repair, and R-loops modulate convergent transcription-induced cell death and repeat instability |
| Q34297995 | Polycomb repressive complex 2 and H3K27me3 cooperate with H3K9 methylation to maintain heterochromatin protein 1α at chromatin |
| Q28743986 | Prolonged treatment with pimelic o-aminobenzamide HDAC inhibitors ameliorates the disease phenotype of a Friedreich ataxia mouse model |
| Q39139063 | RNA toxicity and foci formation in microsatellite expansion diseases |
| Q37095593 | Rationale for the development of 2-aminobenzamide histone deacetylase inhibitors as therapeutics for Friedreich ataxia |
| Q34575655 | Repeat expansion affects both transcription initiation and elongation in friedreich ataxia cells |
| Q37696972 | Repeat expansion disease: progress and puzzles in disease pathogenesis |
| Q37021501 | Reversal of epigenetic promoter silencing in Friedreich ataxia by a class I histone deacetylase inhibitor. |
| Q28534708 | Role of CTCF protein in regulating FMR1 locus transcription |
| Q90477216 | SINEUP non-coding RNAs rescue defective frataxin expression and activity in a cellular model of Friedreich's Ataxia |
| Q34720833 | Stem cells from wildtype and Friedreich's ataxia mice present similar neuroprotective properties in dorsal root ganglia cells |
| Q64039292 | Targeted Oligonucleotides for Treating Neurodegenerative Tandem Repeat Diseases |
| Q50129977 | The emerging roles for the chromatin structure regulators CTCF and cohesin in neurodevelopment and behavior. |
| Q28087539 | The promise and perils of HDAC inhibitors in neurodegeneration |
| Q38365167 | The relationship between transcription initiation RNAs and CCCTC-binding factor (CTCF) localization |
| Q63979651 | The transcriptional regulator CCCTC-binding factor limits oxidative stress in endothelial cells |
| Q97530179 | Three-dimensional chromatin interactions remain stable upon CAG/CTG repeat expansion |
| Q34499436 | Transcription elongation and tissue-specific somatic CAG instability |
| Q39230731 | Translating HDAC inhibitors in Friedreich's ataxia. |
| Q26860523 | Understanding the genetic and molecular pathogenesis of Friedreich's ataxia through animal and cellular models |
| Q37736127 | Understanding the molecular mechanisms of Friedreich's ataxia to develop therapeutic approaches. |
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