Paracrine modulation of CXCR4 by IGF-1 and VEGF: implications for choroidal neovascularization

scientific article

Paracrine modulation of CXCR4 by IGF-1 and VEGF: implications for choroidal neovascularization is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1167/IOVS.09-4137
P932PMC publication ID2868476
P698PubMed publication ID20007826
P5875ResearchGate publication ID40685582

P50authorAqeela AfzalQ42843306
Maria B GrantQ88523403
P2093author name stringGerard A Lutty
Takayuki Baba
Nilanjana Sengupta
Sergio Caballero
Vincent C Bond
Lynn C Shaw
Ji-Jing Pang
Imran Bhutto
Kyung-Hee Chang
P2860cites workInvolvement of chemokine receptors in breast cancer metastasisQ24290909
A novel chemokine receptor for SDF-1 and I-TAC involved in cell survival, cell adhesion, and tumor developmentQ24676591
Impaired B-lymphopoiesis, myelopoiesis, and derailed cerebellar neuron migration in CXCR4- and SDF-1-deficient miceQ24681021
CXCR4 regulates growth of both primary and metastatic breast cancerQ28296113
A role for chemokine receptor transactivation in growth factor signaling.Q28360845
The chemokine receptor CXCR4 is essential for vascularization of the gastrointestinal tractQ28504884
The chemokine SDF1/CXCL12 and its receptor CXCR4 regulate mouse germ cell migration and survivalQ28511571
Sphingosine 1-phosphate transactivates the platelet-derived growth factor beta receptor and epidermal growth factor receptor in vascular smooth muscle cellsQ28576634
The Role of Adult Bone Marrow-Derived Stem Cells in Choroidal NeovascularizationQ31017364
Preventing stem cell incorporation into choroidal neovascularization by targeting homing and attachment factorsQ31137884
Localisation of SDF-1 and its receptor CXCR4 in retina and choroid of aged human eyes and in eyes with age related macular degenerationQ35761920
Ranibizumab: Phase III clinical trial resultsQ36578530
Development of ranibizumab, an anti-vascular endothelial growth factor antigen binding fragment, as therapy for neovascular age-related macular degenerationQ36619213
Vascular precursors in developing human retinaQ37090288
Characterization of Nef-CXCR4 interactions important for apoptosis inductionQ40161550
Transactivation of CXCR4 by the insulin-like growth factor-1 receptor (IGF-1R) in human MDA-MB-231 breast cancer epithelial cellsQ40371413
Diverse signaling pathways through the SDF-1/CXCR4 chemokine axis in prostate cancer cell lines leads to altered patterns of cytokine secretion and angiogenesisQ40400042
Activation of epidermal growth factor receptor via CCR3 in bronchial epithelial cellsQ40541313
Role of high expression levels of CXCR4 in tumor growth, vascularization, and metastasisQ40548697
Extracellular Nef protein targets CD4+ T cells for apoptosis by interacting with CXCR4 surface receptorsQ40584535
SDF-1 is both necessary and sufficient to promote proliferative retinopathy.Q40743408
Expression of stromal cell-derived factor 1 and CXCR4 ligand receptor system in pancreatic cancer: a possible role for tumor progressionQ40853389
Localization of collagen XVIII and the endostatin portion of collagen XVIII in aged human control eyes and eyes with age-related macular degenerationQ42460856
Effects of HIV-1 Nef, a cytotoxic viral protein, on the growth of primary colorectal cancerQ44120901
Sphingosine 1-phosphate and platelet-derived growth factor (PDGF) act via PDGF beta receptor-sphingosine 1-phosphate receptor complexes in airway smooth muscle cellsQ44248239
Vitreous levels of vascular endothelial growth factor and stromal-derived factor 1 in patients with diabetic retinopathy and cystoid macular edema before and after intraocular injection of triamcinoloneQ45185695
Investigations of RPE cells of choriodal neovascular membranes from patients with age-related macula degeneration.Q47389401
PAR-1 activation on human late endothelial progenitor cells enhances angiogenesis in vitro with upregulation of the SDF-1/CXCR4 system.Q54645645
Migration of Bone Marrow and Cord Blood Mesenchymal Stem Cells In Vitro Is Regulated by Stromal-Derived Factor-1-CXCR4 and Hepatocyte Growth Factor-c-met Axes and Involves Matrix MetalloproteinasesQ57375767
SDF1-alpha is associated with VEGFR-2 in human choroidal neovascularisationQ57838886
Epidermal growth factor (EGF) stimulates EGF receptor synthesisQ68957994
Heterogeneity in localization of isoforms of TGF-beta in human retina, vitreous, and choroidQ72072812
Circulating hematopoietic stem cells in patients with neovascular age-related macular degenerationQ80138085
The SDF-1/CXCR4 ligand/receptor pair is an important contributor to several types of ocular neovascularizationQ80376104
Stromal cell-derived factor-1 (SDF-1) alleles and susceptibility to breast carcinomaQ81888370
Nitric oxide cytoskeletal-induced alterations reverse the endothelial progenitor cell migratory defect associated with diabetesQ82097295
P4510describes a project that usesImageJQ1659584
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectneovascularizationQ1281049
P304page(s)2697-2704
P577publication date2009-12-10
P1433published inInvestigative Ophthalmology Visual ScienceQ6060707
P1476titleParacrine modulation of CXCR4 by IGF-1 and VEGF: implications for choroidal neovascularization
P478volume51

Reverse relations

cites work (P2860)
Q35659330A Simple Optical Coherence Tomography Quantification Method for Choroidal Neovascularization
Q34755199An angiotensin-converting enzyme inhibitor modulates stromal-derived factor-1 through CD26/dipeptidyl peptidase IV to inhibit laser-induced choroidal neovascularization
Q33802700Anaphylatoxins Activate Ca2+, Akt/PI3-Kinase, and FOXO1/FoxP3 in the Retinal Pigment Epithelium
Q28743307Blockade of VEGFR1 and 2 suppresses pathological angiogenesis and vascular leakage in the eye
Q35166644Critical role of SDF-1α-induced progenitor cell recruitment and macrophage VEGF production in the experimental corneal neovascularization.
Q26865091Endothelial tip cells in ocular angiogenesis: potential target for anti-angiogenesis therapy
Q44204333Expression of insulin-like growth factor 1 receptor in rat retina following optic nerve injury
Q37393106Gene expression of IGF1, IGF1R, and IGFBP3 in epiretinal membranes of patients with proliferative diabetic retinopathy: preliminary study.
Q36033617Hedgehog Signaling Components Are Expressed in Choroidal Neovascularization in Laser-induced Retinal Lesion
Q35924203Inhibited experimental corneal neovascularization by neutralizing anti-SDF-1α antibody
Q35020040Laser-induced choroidal neovascularization model to study age-related macular degeneration in mice.
Q27335140Predicted molecular signaling guiding photoreceptor cell migration following transplantation into damaged retina
Q42730614Salvianolic Acid A Inhibits OX-LDL Effects on Exacerbating Choroidal Neovascularization via Downregulating CYLD.
Q33746477Soluble factors secreted by differentiating embryonic stem cells stimulate exogenous cell proliferation and migration.
Q33930876Suppression of choroidal neovascularization through inhibition of APE1/Ref-1 redox activity
Q36083881Understanding age-related macular degeneration (AMD): relationships between the photoreceptor/retinal pigment epithelium/Bruch's membrane/choriocapillaris complex
Q34972337VEGF receptor blockade markedly reduces retinal microglia/macrophage infiltration into laser-induced CNV.
Q28655924Vascular progenitors from cord blood-derived induced pluripotent stem cells possess augmented capacity for regenerating ischemic retinal vasculature

Search more.