Interaction between Hhex and SOX13 modulates Wnt/TCF activity

scientific article

Interaction between Hhex and SOX13 modulates Wnt/TCF activity is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M109.046649
P932PMC publication ID2820800
P698PubMed publication ID20028982

P50authorJosé V CastellQ40003925
Francisco X RealQ54394817
Roque BortQ59702658
P2093author name stringChristophe E Pierreux
Frédéric P Lemaigre
Marta Moya
Vanessa Marfil
P2860cites workThe Sox-13 gene: structure, promoter characterization, and chromosomal localizationQ22009352
The promyelocytic leukemia protein PML interacts with the proline-rich homeodomain protein PRH: a RING may link hematopoiesis and growth controlQ22010929
The proline-rich homeodomain protein recruits members of the Groucho/Transducin-like enhancer of split protein family to co-repress transcription in hematopoietic cellsQ24296022
The transcriptional repressor protein PRH interacts with the proteasomeQ24306300
CK2 phosphorylation of the PRH/Hex homeodomain functions as a reversible switch for DNA bindingQ24310110
The high-mobility-group domain of Sox proteins interacts with DNA-binding domains of many transcription factorsQ24313036
CHD8 is an ATP-dependent chromatin remodeling factor that regulates beta-catenin target genesQ24315938
Interaction between hex and GATA transcription factors in vascular endothelial cells inhibits flk-1/KDR-mediated vascular endothelial growth factor signalingQ24316239
Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinomaQ24336272
HIC1 attenuates Wnt signaling by recruitment of TCF-4 and beta-catenin to the nuclear bodiesQ24337920
High expression of the HMG box factor sox-13 in arterial walls during embryonic developmentQ24546094
Use of chromatin immunoprecipitation to clone novel E2F target promotersQ24548317
ECR Browser: a tool for visualizing and accessing data from comparisons of multiple vertebrate genomesQ24562130
Identification of a novel vertebrate homeobox gene expressed in haematopoietic cellsQ24629002
The regulator of early gliogenesis glial cells missing is a transcription factor with a novel type of DNA-binding domainQ24676998
Divergent homeobox gene hex regulates promoter of the Na(+)-dependent bile acid cotransporterQ28142073
Hex is a transcriptional repressor that contributes to anterior identity and suppresses Spemann organiser functionQ28144015
The homeobox gene Hex is required in definitive endodermal tissues for normal forebrain, liver and thyroid formationQ28144023
Matching SOX: partner proteins and co-factors of the SOX family of transcriptional regulatorsQ28213186
Functional interaction of Jun and homeodomain proteinsQ28215958
Hex acts with beta-catenin to regulate anteroposterior patterning via a Groucho-related co-repressor and NodalQ28260303
DKK1, a negative regulator of Wnt signaling, is a target of the beta-catenin/TCF pathwayQ28283034
A null mutation of Hhex results in abnormal cardiac development, defective vasculogenesis and elevated Vegfa levelsQ28285594
A genome-wide association study identifies novel risk loci for type 2 diabetesQ28287727
HEX expression and localization in normal mammary gland and breast carcinomaQ28504757
Hex homeobox gene controls the transition of the endoderm to a pseudostratified, cell emergent epithelium for liver bud developmentQ28505706
Requirement for beta-catenin in anterior-posterior axis formation in miceQ28507627
Homeobox gene Hex is essential for onset of mouse embryonic liver development and differentiation of the monocyte lineageQ28507917
SOX9 is required for maintenance of the pancreatic progenitor cell poolQ28510325
The HMG box transcription factor Sox4 contributes to the development of the endocrine pancreasQ28512013
The homeobox gene HEX regulates proliferation and differentiation of hemangioblasts and endothelial cells during ES cell differentiationQ28513986
cDNA cloning and expression of rat homeobox gene, Hex, and functional characterization of the proteinQ28580425
Depletion of definitive gut endoderm in Sox17-null mutant miceQ28586636
The homeobox gene Hhex is essential for proper hepatoblast differentiation and bile duct morphogenesisQ28588578
Hhex is a direct repressor of endothelial cell-specific molecule 1 (ESM-1)Q28589783
Intrahepatic bile ducts develop according to a new mode of tubulogenesis regulated by the transcription factor SOX9Q28591815
Hex homeobox gene-dependent tissue positioning is required for organogenesis of the ventral pancreasQ28592392
Impaired B cell development and function in mice with a targeted disruption of the homeobox gene HexQ28594302
The homeoprotein Hex is required for hemangioblast differentiationQ28594869
Solubilization and purification of enzymatically active glutathione S-transferase (pGEX) fusion proteinsQ29615167
Identification of a new family of tissue-specific basic helix-loop-helix proteins with a two-hybrid systemQ29620436
Sex-determining region Y-related protein SOX13 is a diabetes autoantigen expressed in pancreatic isletsQ33907243
A lentiviral microRNA-based system for single-copy polymerase II-regulated RNA interference in mammalian cellsQ33938488
Aberrant eukaryotic translation initiation factor 4E-dependent mRNA transport impedes hematopoietic differentiation and contributes to leukemogenesisQ34987550
Back to basics: Sox genesQ36856246
SOX13 exhibits a distinct spatial and temporal expression pattern during chondrogenesis, neurogenesis, and limb developmentQ37644108
Induction of the primary dorsalizing center in Xenopus by the Wnt/GSK/beta-catenin signaling pathway, but not by Vg1, Activin or NogginQ38350046
Regulation of gammadelta versus alphabeta T lymphocyte differentiation by the transcription factor SOX13.Q40184032
Underexpressed coactivators PGC1alpha and SRC1 impair hepatocyte nuclear factor 4 alpha function and promote dedifferentiation in human hepatoma cells.Q40246865
Heart induction by Wnt antagonists depends on the homeodomain transcription factor Hex.Q40974831
Expression of Hex homeobox gene during skin development: Increase in epidermal cell proliferation by transfecting the Hex to the dermisQ42524736
Adenovirus-mediated transfer of the muscle glycogen phosphorylase gene into hepatocytes confers altered regulation of glycogen metabolismQ44509062
Mesodermal Wnt2b signalling positively regulates liver specification.Q45995605
Regulation of hhex expression in the yolk syncytial layer, the potential Nieuwkoop center homolog in zebrafishQ47073176
Identification of the transactivating region of the homeodomain protein, hex.Q47871163
The transcription factor hepatocyte nuclear factor-6/Onecut-1 controls the expression of its paralog Onecut-3 in developing mouse endodermQ50792142
Distinct populations of endoderm cells converge to generate the embryonic liver bud and ventral foregut tissuesQ52055135
Expression of Sox transcription factors in the developing mouse pancreasQ52103921
Hex expression suggests a role in the development and function of organs derived from foregut endodermQ52165490
Hex: a homeobox gene revealing peri-implantation asymmetry in the mouse embryo and an early transient marker of endothelial cell precursorsQ52191962
Transcriptional Activation of CYP2C9, CYP1A1, and CYP1A2 by Hepatocyte Nuclear Factor 4 Requires Coactivators Peroxisomal Proliferator Activated Receptor- Coactivator 1 and Steroid Receptor Coactivator 1Q58681142
Transcriptional activation of CYP2C9, CYP1A1, and CYP1A2 by hepatocyte nuclear factor 4alpha requires coactivators peroxisomal proliferator activated receptor-gamma coactivator 1alpha and steroid receptor coactivator 1Q64377587
Repression of Wnt/beta-catenin signaling in the anterior endoderm is essential for liver and pancreas developmentQ80346251
Gene transfer into mouse prepancreatic endoderm by whole embryo electroporationQ81522547
P433issue8
P407language of work or nameEnglishQ1860
P1104number of pages12
P304page(s)5726-5737
P577publication date2009-12-22
P1433published inJournal of Biological ChemistryQ867727
P1476titleInteraction between Hhex and SOX13 modulates Wnt/TCF activity
P478volume285

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cites work (P2860)
Q38426867A Network of High-Mobility Group Box Transcription Factors Programs Innate Interleukin-17 Production
Q38992187CK2 abrogates the inhibitory effects of PRH/HHEX on prostate cancer cell migration and invasion and acts through PRH to control cell proliferation.
Q37781276Determining γδ versus αß T cell development.
Q36877444Diabetes genes identified by genome-wide association studies are regulated in mice by nutritional factors in metabolically relevant tissues and by glucose concentrations in islets
Q92283827Evaluation of PAX8 expression promotes the proliferation of stomach Cancer cells
Q34845862Fine time course expression analysis identifies cascades of activation and repression and maps a putative regulator of mammalian sex determination
Q28390991Forfeited hepatogenesis program and increased embryonic stem cell traits in young hepatocellular carcinoma (HCC) comparing to elderly HCC
Q38956629Growth-promoting and tumourigenic activity of c-Myc is suppressed by Hhex
Q33575322Heritability and genomics of gene expression in peripheral blood
Q34576961High Throughput Genomic Screen Identifies Multiple Factors That Promote Cooperative Wnt Signaling
Q27319643Multi-label multi-instance transfer learning for simultaneous reconstruction and cross-talk modeling of multiple human signaling pathways
Q52608499STAT6, PBX2, and PBRM1 Emerge as Predicted Regulators of 452 Differentially Expressed Genes Associated With Puberty in Brahman Heifers.
Q95933563Sox13 promotes hepatocellular carcinoma metastasis by transcriptionally activating Twist1

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