Dysbindin regulates the transcriptional level of myristoylated alanine-rich protein kinase C substrate via the interaction with NF-YB in mice brain

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Dysbindin regulates the transcriptional level of myristoylated alanine-rich protein kinase C substrate via the interaction with NF-YB in mice brain is …
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scholarly articleQ13442814

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P819ADS bibcode2010PLoSO...5.8773O
P356DOI10.1371/JOURNAL.PONE.0008773
P932PMC publication ID2808252
P698PubMed publication ID20098743
P5875ResearchGate publication ID41124124

P50authorRyusuke KuwaharaQ57624141
Ryota HashimotoQ63043161
Hiroaki OkudaQ40017133
P2093author name stringTaiichi Katayama
Masaya Tohyama
Shoko Shimizu
Keisuke Kawamoto
Kohei Yamada
Masatoshi Takeda
Natsuko Kumamoto
Shingo Miyata
Shinsuke Matsuzaki
Tsuyoshi Hattori
P2860cites workAssociation between the DTNBP1 gene and intelligence: a case-control study in young patients with schizophrenia and related disorders and unaffected siblingsQ21203814
Association of neuregulin 1 with schizophrenia confirmed in a Scottish populationQ24561773
Genetic variation in the 6p22.3 gene DTNBP1, the human ortholog of the mouse dysbindin gene, is associated with schizophreniaQ24612644
Neuregulin 1 and susceptibility to schizophreniaQ24616921
Disruption of two novel genes by a translocation co-segregating with schizophreniaQ28144559
Disrupted-In-Schizophrenia 1, a candidate gene for schizophrenia, participates in neurite outgrowthQ28188775
Confirming RGS4 as a susceptibility gene for schizophreniaQ28241823
Effectiveness of antipsychotic drugs in patients with chronic schizophreniaQ28273164
Dysbindin, a novel coiled-coil-containing protein that interacts with the dystrobrevins in muscle and brainQ28505394
Dysbindin engages in c-Jun N-terminal kinase activity and cytoskeletal organizationQ28508993
Evidence of novel neuronal functions of dysbindin, a susceptibility gene for schizophreniaQ28568230
The neuregulin-1 receptor erbB4 controls glutamatergic synapse maturation and plasticity.Q28568657
Effect of COMT Val108/158 Met genotype on frontal lobe function and risk for schizophreniaQ29614929
NMDA receptor trafficking in synaptic plasticity and neuropsychiatric disordersQ29617936
A novel DISC1-interacting partner DISC1-Binding Zinc-finger protein: implication in the modulation of DISC1-dependent neurite outgrowth.Q30830598
Synaptic plasticity and dysconnection in schizophreniaQ31030180
Ziskind-Somerfeld Research Award. Protein kinase C signaling in the brain: molecular transduction of mood stabilization in the treatment of manic-depressive illnessQ33782621
Xenopus NF-Y pre-sets chromatin to potentiate p300 and acetylation-responsive transcription from the Xenopus hsp70 promoter in vivoQ33889834
The DTNBP1 (dysbindin) gene contributes to schizophrenia, depending on family history of the diseaseQ33905352
Association of the DTNBP1 locus with schizophrenia in a U.S. populationQ33910454
Two pathways control chromaffin cell cortical F-actin dynamics during exocytosisQ33949121
Identification in 2 independent samples of a novel schizophrenia risk haplotype of the dystrobrevin binding protein gene (DTNBP1).Q33977237
Strong evidence for association between the dystrobrevin binding protein 1 gene (DTNBP1) and schizophrenia in 488 parent-offspring trios from BulgariaQ33977974
Glutamate and schizophrenia: beyond the dopamine hypothesisQ33996803
Role of the CCAAT-binding protein CBF/NF-Y in transcriptionQ34470368
Variation in the dysbindin gene and normal cognitive function in three independent population samples.Q51944823
Variance in neurocognitive performance is associated with dysbindin-1 in schizophrenia: a preliminary study.Q52009093
Haplotypes at the dystrobrevin binding protein 1 (DTNBP1) gene locus mediate risk for schizophrenia through reduced DTNBP1 expression.Q53621277
A dysbindin risk haplotype associated with less severe manic-type symptoms in psychosisQ57699655
Evidence for a susceptibility locus for schizophrenia on chromosome 6pter–p22Q71990853
Family-based association study of DTNBP1 in 6p22.3 and schizophreniaQ73729298
Neurobiology of schizophreniaQ79173267
RNF151, a testis-specific RING finger protein, interacts with dysbindinQ80496881
Relationship between a high-risk haplotype in the DTNBP1 (dysbindin) gene and clinical features of schizophreniaQ81299308
Genetic variation in DTNBP1 influences general cognitive abilityQ34484915
Hyperactivation of midbrain dopaminergic system in schizophrenia could be attributed to the down-regulation of dysbindin.Q34526304
Pathophysiologically based treatment interventions in schizophreniaQ34570681
Synaptotagmin I, a Ca2+ sensor for neurotransmitter releaseQ35192506
New Aspects of Neurotransmitter Release and Exocytosis: Rho-Kinase-Dependent Myristoylated Alanine-Rich C-Kinase Substrate Phosphorylation and Regulation of Neurofilament Structure in Neuronal CellsQ35538979
Bringing order to the glutamate chaos in schizophreniaQ35601575
Evolution of antipsychotic intervention in the schizophrenic psychosisQ36611887
Phencyclidine animal models of schizophrenia: approaches from abnormality of glutamatergic neurotransmission and neurodevelopmentQ36899309
A highly significant association between a COMT haplotype and schizophrenia.Q37203703
Dysbindin-1 is reduced in intrinsic, glutamatergic terminals of the hippocampal formation in schizophreniaQ37698891
Levels of mRNAs encoding synaptic vesicle and synaptic plasma membrane proteins in the temporal cortex of elderly schizophrenic patientsQ38309861
Requirement for down-regulation of the CCAAT-binding activity of the NF-Y transcription factor during skeletal muscle differentiation.Q39791058
Dynamic recruitment of transcription factors and epigenetic changes on the ER stress response gene promotersQ40270857
Support for association of schizophrenia with genetic variation in the 6p22.3 gene, dysbindin, in sib-pair families with linkage and in an additional sample of triad familiesQ40722387
Genomic structure and localisation within a linkage hotspot of Disrupted In Schizophrenia 1, a gene disrupted by a translocation segregating with schizophrenia.Q40810638
Involvement of protein kinase C-epsilon in activity-dependent potentiation of large dense-core vesicle exocytosis in chromaffin cells.Q42500692
Association and linkage analyses of RGS4 polymorphisms in schizophreniaQ42676740
Neurocognitive correlates of the COMT Val(158)Met polymorphism in chronic schizophrenia.Q44174109
Support for RGS4 as a susceptibility gene for schizophreniaQ44734498
Identification of a high-risk haplotype for the dystrobrevin binding protein 1 (DTNBP1) gene in the Irish study of high-density schizophrenia familiesQ44894348
Regulator of G-protein signaling 4 (RGS4) gene is associated with schizophrenia in Irish high density familiesQ44903817
A potential vulnerability locus for schizophrenia on chromosome 6p24-22: evidence for genetic heterogeneity.Q45081613
Behavioral abnormalities and dopamine reductions in sdy mutant mice with a deletion in Dtnbp1, a susceptibility gene for schizophrenia.Q46538656
Synaptically driven endocannabinoid release requires Ca2+-assisted metabotropic glutamate receptor subtype 1 to phospholipase Cbeta4 signaling cascade in the cerebellum.Q46610682
Effect of antipsychotic drugs on DISC1 and dysbindin expression in mouse frontal cortex and hippocampus.Q46931688
Dopamine receptor excess and mouse madnessQ46942967
Human dysbindin (DTNBP1) gene expression in normal brain and in schizophrenic prefrontal cortex and midbrainQ47378030
High dopamine turnover in the brains of Sandy mice.Q48147327
Abnormal dysbindin expression in cerebellar mossy fiber synapses in the mdx mouse model of Duchenne muscular dystrophy.Q48246615
Dysbindin (DTNBP1, 6p22.3) is associated with childhood-onset psychosis and endophenotypes measured by the Premorbid Adjustment Scale (PAS).Q50305183
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)e8773
P577publication date2010-01-19
P1433published inPLOS OneQ564954
P1476titleDysbindin regulates the transcriptional level of myristoylated alanine-rich protein kinase C substrate via the interaction with NF-YB in mice brain
P478volume5

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cites work (P2860)
Q37723680Alterations of the myristoylated, alanine-rich C kinase substrate (MARCKS) in prefrontal cortex in schizophrenia
Q30428226Behavioral characterization of mice overexpressing human dysbindin-1.
Q35875021Cell biology of the BLOC-1 complex subunit dysbindin, a schizophrenia susceptibility gene.
Q88667593Dysbindin-1 contributes to prefrontal cortical dendritic arbor pathology in schizophrenia
Q30474256Dysbindin-containing complexes and their proposed functions in brain: from zero to (too) many in a decade.
Q38321358Molecular basis of major psychiatric diseases such as schizophrenia and depression
Q37952284NF-Y and the transcriptional activation of CCAAT promoters.
Q24301877Nucleocytoplasmic Shuttling of Dysbindin-1, a Schizophrenia-related Protein, Regulates Synapsin I Expression
Q33803921Reduced rate of neural differentiation in the dentate gyrus of adult dysbindin null (sandy) mouse
Q24625434Schizophrenia susceptibility gene dysbindin regulates glutamatergic and dopaminergic functions via distinctive mechanisms in Drosophila
Q35690513The Schizophrenia-Related Protein Dysbindin-1A Is Degraded and Facilitates NF-Kappa B Activity in the Nucleus

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