scholarly article | Q13442814 |
P819 | ADS bibcode | 2010PNAS..107.4573Z |
P356 | DOI | 10.1073/PNAS.0909133107 |
P932 | PMC publication ID | 2842023 |
P698 | PubMed publication ID | 20167798 |
P5875 | ResearchGate publication ID | 41486435 |
P50 | author | Scott G. Franzblau | Q39482766 |
Jie Xu | Q91794273 | ||
P2093 | author name string | Yong Luo | |
Yan Liu | |||
Zhong-Yin Zhang | |||
Bo Zhou | |||
Xian Zhang | |||
Rebecca J Chan | |||
Yantao He | |||
Yuehong Wang | |||
Jianyu Zheng | |||
Zhenyun Yang | |||
P2860 | cites work | Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence | Q22122411 |
Structural Basis for Selective Inhibition of Mycobacterium tuberculosis Protein Tyrosine Phosphatase PtpB | Q27644471 | ||
Click Chemistry: Diverse Chemical Function from a Few Good Reactions | Q28204398 | ||
Interferon-γ: an overview of signals, mechanisms and functions | Q28207081 | ||
Protein tyrosine phosphatases in the human genome | Q28265924 | ||
The magic bullets and tuberculosis drug targets. | Q30350532 | ||
Aurintricarboxylic acid blocks in vitro and in vivo activity of YopH, an essential virulent factor of Yersinia pestis, the agent of plague. | Q31151176 | ||
A potent and highly selective inhibitor of human alpha-1,3-fucosyltransferase via click chemistry | Q33188039 | ||
Rapid assembly and in situ screening of bidentate inhibitors of protein tyrosine phosphatases | Q33233529 | ||
A two stage click-based library of protein tyrosine phosphatase inhibitors | Q33260614 | ||
Parallel synthesis of a multi-substituted benzo[b]furan library. | Q33378183 | ||
Inhibition of MptpB phosphatase from Mycobacterium tuberculosis impairs mycobacterial survival in macrophages | Q33412046 | ||
In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis | Q33722005 | ||
Identification of p130Cas as a substrate of Yersinia YopH (Yop51), a bacterial protein tyrosine phosphatase that translocates into mammalian cells and targets focal adhesions | Q33886658 | ||
Protein tyrosine phosphatases: structure and function, substrate specificity, and inhibitor development | Q34110887 | ||
Combinatorial control of the specificity of protein tyrosine phosphatases | Q34180660 | ||
Protein tyrosine phosphatases: prospects for therapeutics | Q34318066 | ||
Interleukin-6 gene-deficient mice show impaired defense against pneumococcal pneumonia | Q34433776 | ||
Discovery of protein phosphatase inhibitor classes by biology-oriented synthesis | Q34771016 | ||
Interplay between mycobacteria and host signalling pathways | Q35745231 | ||
Targeting virulence: a new paradigm for antimicrobial therapy | Q36914994 | ||
Intracellular bacterial growth is controlled by a kinase network around PKB/AKT1. | Q40043123 | ||
Interferon-gamma induces C/EBP beta expression and activity through MEK/ERK and p38 in T84 colon epithelial cells. | Q40680288 | ||
ERK1 and ERK2 activate CCAAAT/enhancer-binding protein-beta-dependent gene transcription in response to interferon-gamma | Q40854135 | ||
The Salmonella effector SptP dephosphorylates host AAA+ ATPase VCP to promote development of its intracellular replicative niche | Q43074065 | ||
Fragment-based substrate activity screening method for the identification of potent inhibitors of the Mycobacterium tuberculosis phosphatase PtpB. | Q44448705 | ||
Disruption of mptpB impairs the ability of Mycobacterium tuberculosis to survive in guinea pigs. | Q44655558 | ||
In situ click chemistry: enzyme inhibitors made to their own specifications | Q45093957 | ||
Brunsvicamides A−C: Sponge-Related Cyanobacterial Peptides withMycobacteriumtuberculosisProtein Tyrosine Phosphatase Inhibitory Activity | Q57007066 | ||
New fronts in an old war | Q59097546 | ||
Structure-based discovery of small molecule inhibitors targeted to protein tyrosine phosphatase 1B | Q73390423 | ||
Click chemistry in situ: acetylcholinesterase as a reaction vessel for the selective assembly of a femtomolar inhibitor from an array of building blocks | Q78687582 | ||
P433 | issue | 10 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 4573-4578 | |
P577 | publication date | 2010-02-18 | |
P1433 | published in | Proceedings of the National Academy of Sciences of the United States of America | Q1146531 |
P1476 | title | Targeting mycobacterium protein tyrosine phosphatase B for antituberculosis agents | |
P478 | volume | 107 |
Q34407569 | A combinatorial strategy for the acquisition of potent and specific protein tyrosine phosphatase inhibitors |
Q34660114 | A facile hydroxyindole carboxylic acid based focused library approach for potent and selective inhibitors of Mycobacterium protein tyrosine phosphatase B |
Q35613113 | A potent and selective inhibitor for the UBLCP1 proteasome phosphatase |
Q38237517 | Agents of change - concepts in Mycobacterium tuberculosis Ser/Thr/Tyr phosphosignalling |
Q33736760 | Alterporriol-type dimers from the mangrove endophytic fungus, Alternaria sp. (SK11), and their MptpB inhibitions |
Q48115416 | An attenuated quadruple gene mutant of Mycobacterium tuberculosis imparts protection against tuberculosis in guinea pigs |
Q36296764 | Analysis of the complete genome sequence of Nocardia seriolae UTF1, the causative agent of fish nocardiosis: The first reference genome sequence of the fish pathogenic Nocardia species |
Q36757725 | Antimicrobial resistance and virulence: a successful or deleterious association in the bacterial world? |
Q89592353 | Antimycobacterial Rufomycin Analogues from Streptomyces atratus Strain MJM3502 |
Q35015361 | Asperlones A and B, dinaphthalenone derivatives from a mangrove endophytic fungus Aspergillus sp. 16-5C. |
Q39114153 | Bacterial Virulence Factors: Secreted for Survival. |
Q26768494 | Benzofuran as a promising scaffold for the synthesis of antimicrobial and antibreast cancer agents: A review |
Q30318128 | Better search strategies, hopeful candidates. The search for new antimycobacterial drugs |
Q35815528 | Bicyclic benzofuran and indole-based salicylic acids as protein tyrosine phosphatase inhibitors |
Q46762736 | Biochemical and functional characterizations of tyrosine phosphatases from pathogenic and nonpathogenic mycobacteria: indication of phenyl cyclopropyl methyl-/phenyl butenyl azoles as tyrosine phosphatase inhibitors |
Q36367311 | Cefsulodin Inspired Potent and Selective Inhibitors of mPTPB, a Virulent Phosphatase from Mycobacterium tuberculosis |
Q34210837 | CuAAC click chemistry accelerates the discovery of novel chemical scaffolds as promising protein tyrosine phosphatases inhibitors |
Q34437023 | Design and synthesis of nonpeptidic, small molecule inhibitors for the Mycobacterium tuberculosis protein tyrosine phosphatase PtpB |
Q36615919 | Discovery and evaluation of novel inhibitors of mycobacterium protein tyrosine phosphatase B from the 6-Hydroxy-benzofuran-5-carboxylic acid scaffold |
Q28534388 | Discovery of Mycobacterium tuberculosis protein tyrosine phosphatase B (PtpB) inhibitors from natural products |
Q42010235 | Diversity-Oriented Synthesis for Novel, Selective and Drug-like Inhibitors for a Phosphatase from Mycobacterium Tuberculosis |
Q35052636 | Double click reaction for the acquisition of a highly potent and selective mPTPB inhibitor |
Q40409054 | Drugging the Undruggable: Therapeutic Potential of Targeting Protein Tyrosine Phosphatases. |
Q47236283 | Glutathione-Responsive Selenosulfide Prodrugs as a Platform Strategy for Potent and Selective Mechanism-Based Inhibition of Protein Tyrosine Phosphatases |
Q57050890 | High-resolution crystal structures of the D1 and D2 domains of protein tyrosine phosphatase epsilon for structure-based drug design |
Q35030333 | Hydroxyindole carboxylic acid-based inhibitors for receptor-type protein tyrosine protein phosphatase beta |
Q34353151 | Identification and characterization of novel inhibitors of mPTPB, an essential virulent phosphatase from Mycobacterium tuberculosis |
Q54943520 | Identification of potent chromone embedded [1,2,3]-triazoles as novel anti-tubercular agents. |
Q38982765 | Inhibition of tumor growth by U0126 is associated with induction of interferon-γ production |
Q35621631 | Listeria monocytogenes tyrosine phosphatases affect wall teichoic acid composition and phage resistance |
Q27865268 | Mitogen-activated protein kinases in innate immunity |
Q55081012 | MptpB Promotes Mycobacteria Survival by Inhibiting the Expression of Inflammatory Mediators and Cell Apoptosis in Macrophages. |
Q37138650 | Mycobacterial Protein Tyrosine Phosphatases A and B Inhibitors Augment the Bactericidal Activity of the Standard Anti-tuberculosis Regimen |
Q92126564 | Mycobacterium tuberculosis Inhibits Autocrine Type I IFN Signaling to Increase Intracellular Survival |
Q34565203 | Mycobacterium tuberculosis Serine/Threonine Protein Kinases |
Q98164563 | New insights into the evasion of host innate immunity by Mycobacterium tuberculosis |
Q37855839 | New strategies in fighting TB: targeting Mycobacterium tuberculosis-secreted phosphatases MptpA & MptpB. |
Q33815443 | Nitropropenyl benzodioxole, an anti-infective agent with action as a protein tyrosine phosphatase inhibitor |
Q37780752 | Novel agents to inhibit microbial virulence and pathogenicity |
Q41662986 | Organocatalytic multicomponent reaction for the acquisition of a selective inhibitor of mPTPB, a virulence factor of tuberculosis |
Q34197585 | Oxime-based linker libraries as a general approach for the rapid generation and screening of multidentate inhibitors |
Q40075067 | PPAR-γ and Akt regulate GLUT1 and GLUT3 surface localization during Mycobacterium tuberculosis infection |
Q46515076 | Polymorphisms of 20 regulatory proteins between Mycobacterium tuberculosis and Mycobacterium bovis |
Q35571964 | Protein topology determines cysteine oxidation fate: the case of sulfenyl amide formation among protein families |
Q38600486 | RETRACTED: Targeting Mycobacterial Enzymes with Natural Products |
Q37451962 | Retracted: PknE, a Serine/Threonine Protein Kinase of Mycobacterium tuberculosis Initiates Survival Crosstalk That Also Impacts HIV Coinfection |
Q64098883 | Rufomycin Targets ClpC1 Proteolysis in Mycobacterium tuberculosis and M. abscessus |
Q27680167 | Rv2969c, essential for optimal growth inMycobacterium tuberculosis, is a DsbA-like enzyme that interacts with VKOR-derived peptides and has atypical features of DsbA-like disulfide oxidases |
Q47221711 | SOCS Proteins as Regulators of Inflammatory Responses Induced by Bacterial Infections: A Review. |
Q35035800 | Secretory phosphatases deficient mutant of Mycobacterium tuberculosis imparts protection at the primary site of infection in guinea pigs |
Q39272388 | Serine/Threonine Protein Phosphatase PstP of Mycobacterium tuberculosis Is Necessary for Accurate Cell Division and Survival of Pathogen |
Q26852276 | Small molecule tools for functional interrogation of protein tyrosine phosphatases |
Q33715761 | Structural insights into mode of actions of novel natural Mycobacterium protein tyrosine phosphatase B inhibitors |
Q57095370 | Structure-Based Design of MptpB Inhibitors That Reduce Multidrug-Resistant Mycobacterium tuberculosis Survival and Infection Burden in Vivo |
Q36011217 | Substituted aminopyrimidine protein kinase B (PknB) inhibitors show activity against Mycobacterium tuberculosis |
Q36820914 | Synthesis and Antiproliferative Activities of Benzimidazole-Based Sulfide and Sulfoxide Derivatives |
Q54523118 | Synthesis and evaluation of 6-aza-2'-deoxyuridine monophosphate analogs as inhibitors of thymidylate synthases, and as substrates or inhibitors of thymidine monophosphate kinase in Mycobacterium tuberculosis. |
Q59010578 | Synthesis of New Fluorine Substituted Heterocyclic Nitrogen Systems Derived fromp-Aminosalicylic Acid as Antimycobacterial Agents |
Q59011039 | Synthesis of Substituted Thioureas and Their Sulfur Heterocyclic Systems ofp-Amino Salicylic Acid as Antimycobacterial Agents |
Q36283574 | Systematic Analysis of Mycobacterial Acylation Reveals First Example of Acylation-mediated Regulation of Enzyme Activity of a Bacterial Phosphatase |
Q34660424 | The challenge of new drug discovery for tuberculosis |
Q35106042 | The cyclic peptide ecumicin targeting ClpC1 is active against Mycobacterium tuberculosis in vivo |
Q38930890 | The tyrosine kinase BceF and the phosphotyrosine phosphatase BceD of Burkholderia contaminans are required for efficient invasion and epithelial disruption of a cystic fibrosis lung epithelial cell line |
Q83620297 | Theoretical studies on the interaction of biphenyl inhibitors with Mycobacterium tuberculosis protein tyrosine phosphatase MptpB |
Q34061302 | Therapeutic potential of targeting the oncogenic SHP2 phosphatase |
Q27667338 | Utilization of Nitrophenylphosphates and Oxime-Based Ligation for the Development of Nanomolar Affinity Inhibitors of the Yersinia pestis Outer Protein H (YopH) Phosphatase ‡ |
Search more.