Legionella pneumophila pangenome reveals strain-specific virulence factors.

scientific article

Legionella pneumophila pangenome reveals strain-specific virulence factors. is …
instance of (P31):
scholarly articleQ13442814

External links are
P6179Dimensions Publication ID1019648386
P356DOI10.1186/1471-2164-11-181
P932PMC publication ID2859405
P698PubMed publication ID20236513
P5875ResearchGate publication ID42254575

P50authorGiuseppe D'AuriaQ79769477
Andrés MoyaQ28097651
Amparo LatorreQ28322693
Nuria Jiménez HernándezQ60006187
P2093author name stringFrancesc Peris-Bondia
P2860cites workRole of the Legionella pneumophila rtxA gene in amoebaeQ74261517
Legionella pneumophila CsrA is a pivotal repressor of transmission traits and activator of replicationQ79293753
A community outbreak of Legionnaires' disease: evidence of a cooling tower as the sourceQ83993275
Virulence factor rtx in Legionella pneumophila, evidence suggesting it is a modular multifunctional proteinQ21263201
The CRISPRdb database and tools to display CRISPRs and to generate dictionaries of spacers and repeatsQ21284230
The COG database: an updated version includes eukaryotesQ21284294
CRISPR Provides Acquired Resistance Against Viruses in ProkaryotesQ21508827
Genome analysis of multiple pathogenic isolates of Streptococcus agalactiae: implications for the microbial "pan-genome"Q22066389
Evidence in the Legionella pneumophila genome for exploitation of host cell functions and high genome plasticityQ22122047
tRNAscan-SE: a program for improved detection of transfer RNA genes in genomic sequenceQ24544402
GenomeViz: visualizing microbial genomesQ24799422
Basic local alignment search toolQ25938991
Improved microbial gene identification with GLIMMERQ27860463
Comparative and functional genomic analysis of prokaryotic nickel and cobalt uptake transporters: evidence for a novel group of ATP-binding cassette transportersQ28563578
Cd-hit: a fast program for clustering and comparing large sets of protein or nucleotide sequencesQ29547172
Mauve: multiple alignment of conserved genomic sequence with rearrangementsQ29547292
KAAS: an automatic genome annotation and pathway reconstruction serverQ29617232
Non-opsonic phagocytosis of Legionella pneumophila by macrophages is mediated by phosphatidylinositol 3-kinaseQ33373341
Distribution of Legionella pneumophila serogroups, monoclonal antibody subgroups and DNA sequence types in recent clinical and environmental isolates from England and Wales (2000-2008).Q33401288
Proteomic analysis of Legionella-containing phagosomes isolated from DictyosteliumQ33456567
Legionella and Legionnaires' disease: 25 years of investigationQ33906852
Distribution of Legionella species and serogroups isolated by culture in patients with sporadic community-acquired legionellosis: an international collaborative surveyQ34136087
Programmed cell death in bacteria: proteic plasmid stabilization systemsQ34289952
The microbial pan-genomeQ34453982
Genetic and phenotypic differences between Legionella pneumophila strainsQ34455524
The pangenome structure of Escherichia coli: comparative genomic analysis of E. coli commensal and pathogenic isolatesQ34803749
Involvement of an essential gene, mviN, in murein synthesis in Escherichia coliQ34809747
Bioinformatics identification of MurJ (MviN) as the peptidoglycan lipid II flippase in Escherichia coliQ34843809
A 65-kilobase pathogenicity island is unique to Philadelphia-1 strains of Legionella pneumophilaQ35162381
The SmtB/ArsR family of metalloregulatory transcriptional repressors: Structural insights into prokaryotic metal resistanceQ35164001
Kinase activity of overexpressed HipA is required for growth arrest and multidrug tolerance in Escherichia coliQ35220633
Environmental mimics and the Lvh type IVA secretion system contribute to virulence-related phenotypes of Legionella pneumophilaQ35689293
Evolution of the core and pan-genome of Streptococcus: positive selection, recombination, and genome compositionQ35906447
A comparison of virulence of two strains of Legionella pneumophila based on experimental aerosol infection of guinea-pigsQ36250179
Multigenome analysis identifies a worldwide distributed epidemic Legionella pneumophila clone that emerged within a highly diverse speciesQ36484295
The Staden sequence analysis packageQ36823231
Evolutionary patterns in prokaryotic genomesQ37288034
Legionella pneumophila Dot/Icm translocated substrates: a sum of partsQ37340940
Legionella pneumophila: population genetics, phylogeny and genomicsQ37486976
The perplexing functions and surprising origins of Legionella pneumophila type IV secretion effectors.Q37534884
Ectopic overexpression of wild-type and mutant hipA genes in Escherichia coli: effects on macromolecular synthesis and persister formationQ38313217
Differential annotation of tRNA genes with anticodon CAT in bacterial genomesQ39081828
Contributions of the AmpC beta-lactamase and the AcrAB multidrug efflux system in intrinsic resistance of Escherichia coli K-12 to beta-lactamsQ39473900
A family of stability determinants in pathogenic bacteriaQ39568877
The Legionella pneumophila hel locus encodes intracellularly induced homologs of heavy-metal ion transporters of Alcaligenes spp.Q39824822
Synthesis of bacilysin by Bacillus subtilis branches from prephenate of the aromatic amino acid pathwayQ39951584
The mviN homolog in Burkholderia pseudomallei is essential for viability and virulenceQ40207329
Clinical study of an outbreak of Legionnaire's disease in Alcoy, Southeastern SpainQ40571490
A Dot/Icm-translocated ankyrin protein of Legionella pneumophila is required for intracellular proliferation within human macrophages and protozoa.Q42175516
The complete sequence and analysis of the large virulence plasmid pSS of Shigella sonneiQ42665743
Thiocyanate hydrolase, the primary enzyme initiating thiocyanate degradation in the novel obligately chemolithoautotrophic halophilic sulfur-oxidizing bacterium Thiohalophilus thiocyanoxidans.Q43023511
Dynamic properties of Legionella-containing phagosomes in Dictyostelium amoebaeQ43959366
Comparison of clinical and environmental samples of Legionella pneumophila at the nucleotide sequence levelQ47736281
Relationships between a new type IV secretion system and the icm/dot virulence system of Legionella pneumophilaQ47910965
Identification and characterization of a new conjugation/type IVA secretion system (trb/tra) of Legionella pneumophila Corby localized on two mobile genomic islandsQ48077439
Various bacterial pathogens and symbionts infect the amoeba Dictyostelium discoideum.Q50109694
Antimicrobial activities and antagonists of bacilysin and anticapsin.Q50227602
Phagocytosis of the Legionnaires' disease bacterium (Legionella pneumophila) occurs by a novel mechanism: engulfment within a pseudopod coil.Q54228644
Growth-phase-dependent mobility of the lvh-encoding region in Legionella pneumophila strain Paris.Q54568001
The Genomic Sequence of the Accidental Pathogen Legionella pneumophilaQ57265781
P407language of work or nameEnglishQ1860
P921main subjectLegionella pneumophilaQ147885
P304page(s)181
P577publication date2010-03-17
P1433published inBMC GenomicsQ15765854
P1476titleLegionella pneumophila pangenome reveals strain-specific virulence factors
P478volume11

Reverse relations

cites work (P2860)
Q41190166A Unique cis-Encoded Small Noncoding RNA Is Regulating Legionella pneumophila Hfq Expression in a Life Cycle-Dependent Manner
Q27022300A brief review of software tools for pangenomics
Q35072676A distinct and divergent lineage of genomic island-associated Type IV Secretion Systems in Legionella
Q34276373A neutral theory of genome evolution and the frequency distribution of genes
Q31140251A structural comparison of lipopolysaccharide biosynthesis loci of Legionella pneumophila serogroup 1 strains
Q38618052A supervised statistical learning approach for accurate Legionella pneumophila source attribution during outbreaks.
Q39952605Active and adaptive Legionella CRISPR-Cas reveals a recurrent challenge to the pathogen
Q44148902Analysis of the transcriptome of Legionella pneumophila hfq mutant reveals a new mobile genetic element.
Q92540723Assessing the impact, genomics and evolution of type II secretion across a large, medically important genus: the Legionella type II secretion paradigm
Q28831366CRISPR System Acquisition and Evolution of an Obligate Intracellular Chlamydia-Related Bacterium
Q42119806Ciliates expel environmental Legionella-laden pellets to stockpile food
Q34796849Comparative Genomics Reveal That Host-Innate Immune Responses Influence the Clinical Prevalence of Legionella pneumophila Serogroups.
Q34636578Comparative analyses of Legionella species identifies genetic features of strains causing Legionnaires' disease
Q35465763Comparative and functional genomics of legionella identified eukaryotic like proteins as key players in host-pathogen interactions
Q34450692Comparative genomics of Serratia spp.: two paths towards endosymbiotic life.
Q35074539Comparison of the Legionella pneumophila population structure as determined by sequence-based typing and whole genome sequencing
Q34837417Cytochrome c4 is required for siderophore expression by Legionella pneumophila, whereas cytochromes c1 and c5 promote intracellular infection
Q40117160Different distribution patterns of ten virulence genes in Legionella reference strains and strains isolated from environmental water and patients
Q38708729Dynamics and impact of homologous recombination on the evolution of Legionella pneumophila
Q37260857Dynamics of genome change among Legionella species
Q36952614Epidemiology and associations with climatic conditions of Mycoplasma pneumoniae and Chlamydophila pneumoniae infections among Chinese children hospitalized with acute respiratory infections
Q43321086Expanding our view of genomic diversity in Candidatus Accumulibacter clades
Q35555593Extensive recombination events and horizontal gene transfer shaped the Legionella pneumophila genomes
Q30951614FuncTree: Functional Analysis and Visualization for Large-Scale Omics Data
Q34853375Functional type 1 secretion system involved in Legionella pneumophila virulence
Q39103166Gene flow in environmental Legionella pneumophila leads to genetic and pathogenic heterogeneity within a Legionnaires' disease outbreak
Q34698118Genetic Characterization of Legionella pneumophila Isolated from a Common Watershed in Comunidad Valenciana, Spain
Q36909874Genome Sequence of an Environmental Isolate of the Bacterial Pathogen Legionella pneumophila
Q34456313Genome analysis of Legionella pneumophila strains using a mixed-genome microarray
Q27002940Genome dynamics in Legionella: the basis of versatility and adaptation to intracellular replication
Q37296968Genomic Analysis Reveals Novel Diversity among the 1976 Philadelphia Legionnaires' Disease Outbreak Isolates and Additional ST36 Strains
Q36485107Genomic Investigation of a Legionellosis Outbreak in a Persistently Colonized Hotel
Q35390426Genomic analysis of a Mycobacterium bovis bacillus [corrected] Calmette-Guérin strain isolated from an adult patient with pulmonary tuberculosis..
Q34020362Genomic characterization of a large outbreak of Legionella pneumophila serogroup 1 strains in Quebec City, 2012
Q33792686Genomic fluidity: an integrative view of gene diversity within microbial populations
Q58601556Genomic heterogeneity differentiates clinical and environmental subgroups of Legionella pneumophila sequence type 1
Q35271436High-throughput typing method to identify a non-outbreak-involved Legionella pneumophila strain colonizing the entire water supply system in the town of Rennes, France
Q41564837Identification and characterization of genes, encoding the 3-hydroxybutyrate dehydrogenase and a putative lipase, in an avirulent spontaneous Legionella pneumophila serogroup 6 mutant
Q42870374Identification and functional characterization of K(+) transporters encoded by Legionella pneumophila kup genes.
Q34065404Insight into cross-talk between intra-amoebal pathogens
Q35315784Intragenic recombination has a critical role on the evolution of Legionella pneumophila virulence-related effector sidJ
Q37129897Iron Limitation Triggers Early Egress by the Intracellular Bacterial Pathogen Legionella pneumophila
Q40307539Isolation and identification of Legionella spp. from different aquatic sources in south-west of Iran by molecular &culture methods
Q37827559Lateral genetic transfer and the construction of genetic exchange communities
Q35075799Lcl of Legionella pneumophila is an immunogenic GAG binding adhesin that promotes interactions with lung epithelial cells and plays a crucial role in biofilm formation.
Q36053598Legionella pneumophila Effector LpdA Is a Palmitoylated Phospholipase D Virulence Factor
Q30155870Legionella pneumophila LbtU acts as a novel, TonB-independent receptor for the legiobactin siderophore
Q35807062Legionella pneumophila sequence type 1/Paris pulsotype subtyping by spoligotyping
Q34291207Legionella pneumophila strain 130b possesses a unique combination of type IV secretion systems and novel Dot/Icm secretion system effector proteins
Q36915737Legionella pneumophila strain associated with the first evidence of person-to-person transmission of Legionnaires' disease: a unique mosaic genetic backbone
Q42650291Legionnaires' Disease Outbreak Caused by Endemic Strain of Legionella pneumophila, New York, New York, USA, 2015
Q39092099Live genomics for pathogen monitoring in public health.
Q37142298Metabolism of myo-Inositol by Legionella pneumophila Promotes Infection of Amoebae and Macrophages
Q34154218Metabolism of the vacuolar pathogen Legionella and implications for virulence
Q35202685Minimization of the Legionella pneumophila genome reveals chromosomal regions involved in host range expansion
Q51735031Modules of co-occurrence in the cyanobacterial pan-genome reveal functional associations between groups of ortholog genes.
Q35029116Molecular Detection of Legionella: Moving on From mip.
Q47247130Molecular evolution of key genes for type II secretion in Legionella pneumophila
Q41577231Nuclease activity of Legionella pneumophila Cas2 promotes intracellular infection of amoebal host cells
Q26864957Nutrient salvaging and metabolism by the intracellular pathogen Legionella pneumophila
Q30362369Oligomerization inhibits Legionella pneumophila PlaB phospholipase A activity.
Q35708459PGAP: pan-genomes analysis pipeline
Q58729059PGAweb: A Web Server for Bacterial Pan-Genome Analysis
Q36738428PanCoreGen - Profiling, detecting, annotating protein-coding genes in microbial genomes
Q59798430PanDelos: a dictionary-based method for pan-genome content discovery
Q35891241Pangenome-wide and molecular evolution analyses of the Pseudomonas aeruginosa species.
Q34438667Phenylalanine hydroxylase from Legionella pneumophila is a thermostable enzyme with a major functional role in pyomelanin synthesis
Q35067041Post-translational modifications are key players of the Legionella pneumophila infection strategy
Q34931764Protein kinase LegK2 is a type IV secretion system effector involved in endoplasmic reticulum recruitment and intracellular replication of Legionella pneumophila
Q42226717Real-time investigation of a Legionella pneumophila outbreak using whole genome sequencing
Q35301668Recombination drives genome evolution in outbreak-related Legionella pneumophila isolates.
Q39797873Regulation, integrase-dependent excision, and horizontal transfer of genomic islands in Legionella pneumophila
Q33847885Sequencing illustrates the transcriptional response of Legionella pneumophila during infection and identifies seventy novel small non-coding RNAs
Q35155330Small Regulatory RNA and Legionella pneumophila.
Q38930726Soluble NSF attachment protein receptor molecular mimicry by a Legionella pneumophila Dot/Icm effector.
Q28078953Space: A Final Frontier for Vacuolar Pathogens
Q39022294Suppressing the CRISPR/Cas adaptive immune system in bacterial infections
Q36706289The CRISPR-associated gene cas2 of Legionella pneumophila is required for intracellular infection of amoebae
Q35042786The Legionella pneumophila Chaperonin - An Unusual Multifunctional Protein in Unusual Locations
Q36053556The Legionella pneumophila Siderophore Legiobactin Is a Polycarboxylate That Is Identical in Structure to Rhizoferrin
Q36004904The bacterial pangenome as a new tool for analysing pathogenic bacteria
Q30152955The composition of the global and feature specific cyanobacterial core-genomes
Q41922057The evolutionary divergence of Shiga toxin-producing Escherichia coli is reflected in clustered regularly interspaced short palindromic repeat (CRISPR) spacer composition
Q54350018The htpAB operon of Legionella pneumophila cannot be deleted in the presence of the groE chaperonin operon of Escherichia coli.
Q35959585The major facilitator superfamily-type protein LbtC promotes the utilization of the legiobactin siderophore by Legionella pneumophila
Q41727068The novel Legionella pneumophila type II secretion substrate NttC contributes to infection of amoebae Hartmannella vermiformis and Willaertia magna
Q35362525The surfactant of Legionella pneumophila Is secreted in a TolC-dependent manner and is antagonistic toward other Legionella species
Q92641282Type I-F CRISPR-Cas Distribution and Array Dynamics in Legionella pneumophila
Q37899756Type IVB Secretion Systems of Legionella and Other Gram-Negative Bacteria.
Q33899930Validation of a microbead-based format for spoligotyping of Legionella pneumophila.
Q51148471Virulence traits of environmental and clinical Legionella pneumophila MLVA genotypes.
Q35806034Whole-genome sequence of the human pathogen Legionella pneumophila serogroup 12 strain 570-CO-H.
Q41953518Zinc metalloproteinase ProA directly activates Legionella pneumophila PlaC glycerophospholipid:cholesterol acyltransferase

Search more.