What can we learn about the distribution of fitness effects of new mutations from DNA sequence data?

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What can we learn about the distribution of fitness effects of new mutations from DNA sequence data? is …
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scholarly articleQ13442814

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P356DOI10.1098/RSTB.2009.0266
P8608Fatcat IDrelease_ypldanrw3vfklcg4bwx5wuz42y
P932PMC publication ID2871813
P698PubMed publication ID20308093
P5875ResearchGate publication ID42389115

P50authorAdam Eyre-WalkerQ30001938
P2093author name stringPeter D Keightley
P2860cites workThe effect of background selection against deleterious mutations on weakly selected, linked variantsQ72180672
MUTATION AND EXTINCTION: THE ROLE OF VARIABLE MUTATIONAL EFFECTS, SYNERGISTIC EPISTASIS, BENEFICIAL MUTATIONS, AND DEGREE OF OUTCROSSINGQ88207432
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The pattern of neutral molecular variation under the background selection modelQ24533194
Imperfect genes, Fisherian mutation and the evolution of sexQ24533237
The genome sequence of Drosophila melanogasterQ27860796
Characterization of single-nucleotide polymorphisms in coding regions of human genesQ28138557
Adaptive protein evolution at the Adh locus in DrosophilaQ28302478
The distribution of mutation effects on viability in Drosophila melanogasterQ28769454
Estimating the distribution of selection coefficients from phylogenetic data with applications to mitochondrial and viral DNA.Q30798810
Assessing the evolutionary impact of amino acid mutations in the human genomeQ33339383
Estimating selection on nonsynonymous mutationsQ34587600
The other side of the nearly neutral theory, evidence of slightly advantageous back-mutationsQ36089115
Low nucleotide diversity in manQ42066951
Estimating the rate of adaptive molecular evolution in the presence of slightly deleterious mutations and population size changeQ42624915
Joint inference of the distribution of fitness effects of deleterious mutations and population demography based on nucleotide polymorphism frequenciesQ42986735
Contrasting patterns of X-linked and autosomal nucleotide variation in Drosophila melanogaster and Drosophila simulans.Q52586421
A Simplex Method for Function MinimizationQ55954356
The Nearly Neutral Theory of Molecular EvolutionQ55968685
Quantifying the Slightly Deleterious Mutation Model of Molecular EvolutionQ57675399
Background selection and patterns of genetic diversity in Drosophila melanogasterQ71827689
P433issue1544
P407language of work or nameEnglishQ1860
P1104number of pages7
P304page(s)1187-1193
P577publication date2010-04-01
P1433published inPhilosophical Transactions of the Royal Society BQ2153239
P1476titleWhat can we learn about the distribution of fitness effects of new mutations from DNA sequence data?
P478volume365

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cites work (P2860)
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