OXA-58, a novel class D {beta}-lactamase involved in resistance to carbapenems in Acinetobacter baumannii

scientific article

OXA-58, a novel class D {beta}-lactamase involved in resistance to carbapenems in Acinetobacter baumannii is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1128/AAC.49.1.202-208.2005
P932PMC publication ID538857
P698PubMed publication ID15616297
P5875ResearchGate publication ID8114813

P50authorLaurent PoirelQ57551509
Patrice NordmannQ63214194
Claire HéritierQ114722292
P2093author name stringChristine Segonds
Gérard Chabanon
Sophie Marqué
P2860cites workCharacterization of a nosocomial outbreak caused by a multiresistant Acinetobacter baumannii strain with a carbapenem-hydrolyzing enzyme: high-level carbapenem resistance in A. baumannii is not due solely to the presence of beta-lactamases.Q39461202
Characterization of OXA-25, OXA-26, and OXA-27, molecular class D beta-lactamases associated with carbapenem resistance in clinical isolates of Acinetobacter baumanniiQ39476331
IMP-4, a novel metallo-beta-lactamase from nosocomial Acinetobacter spp. collected in Hong Kong between 1994 and 1998.Q39476492
Emergence in Klebsiella pneumoniae of a chromosome-encoded SHV beta-lactamase that compromises the efficacy of imipenemQ39740513
OXA-18, a class D clavulanic acid-inhibited extended-spectrum beta-lactamase from Pseudomonas aeruginosa.Q39785056
Imipenem resistance in Acinetobacter baumanii is due to altered penicillin-binding proteinsQ41171839
A comparative study of class-D beta-lactamasesQ42068354
Molecular characterization of bla(IMP-5), a new integron-borne metallo-beta-lactamase gene from an Acinetobacter baumannii nosocomial isolate in PortugalQ43169315
Molecular characterization of metallo-beta-lactamase-producing Acinetobacter baumannii and Acinetobacter genomospecies 3 from Korea: identification of two new integrons carrying the bla(VIM-2) gene cassettesQ43988737
AmpC cephalosporinase hyperproduction in Acinetobacter baumannii clinical strainsQ44570697
ARI 1: beta-lactamase-mediated imipenem resistance in Acinetobacter baumanniiQ47867439
Phylogeny of LCR-1 and OXA-5 with class A and class D beta-lactamasesQ48171154
Endemic carbapenem-resistant Acinetobacter species in Brooklyn, New York: citywide prevalence, interinstitutional spread, and relation to antibiotic usage.Q54043075
Limitation of Acinetobacter baumannii treatment by plasmid-mediated carbapenemase ARI-2.Q54148645
Transferable imipenem-resistance in Acinetobacter species from a clinical source.Q54162810
Factors affecting the isolation of CCC DNA from Streptomyces lividans and Escherichia coliQ70391537
Imipenem resistance among Acinetobacter baumannii: association with reduced expression of a 33-36 kDa outer membrane proteinQ71698688
Worldwide emergence of carbapenem-resistant Acinetobacter sppQ74661529
Sequence analysis of ARI-1, a novel OXA beta-lactamase, responsible for imipenem resistance in Acinetobacter baumannii 6B92Q95811508
OXA-type beta-lactamasesQ33762371
Emergence and rapid spread of carbapenem resistance during a large and sustained hospital outbreak of multiresistant Acinetobacter baumannii.Q33970252
Molecular and biochemical characterization of VEB-1, a novel class A extended-spectrum beta-lactamase encoded by an Escherichia coli integron geneQ33976426
Cloning, nucleotide sequencing, and analysis of the gene encoding an AmpC beta-lactamase in Acinetobacter baumanniiQ33978798
Characterization of the metallo-beta-lactamase determinant of Acinetobacter baumannii AC-54/97 reveals the existence of bla(IMP) allelic variants carried by gene cassettes of different phylogenyQ33979415
OXA-24, a novel class D beta-lactamase with carbapenemase activity in an Acinetobacter baumannii clinical strainQ33979698
OXA-28, an extended-spectrum variant of OXA-10 beta-lactamase from Pseudomonas aeruginosa and its plasmid- and integron-located geneQ33981359
Oxacillinase-mediated resistance to cefepime and susceptibility to ceftazidime in Pseudomonas aeruginosaQ33982181
Acquired carbapenem-hydrolyzing beta-lactamases and their genetic supportQ34647842
Genetic and functional analysis of the chromosome-encoded carbapenem-hydrolyzing oxacillinase OXA-40 of Acinetobacter baumanniiQ34723087
PCR typing of genetic determinants for metallo-beta-lactamases and integrases carried by gram-negative bacteria isolated in Japan, with focus on the class 3 integronQ34954694
Emergence of oxacillinase-mediated resistance to imipenem in Klebsiella pneumoniaeQ35005872
Chromosome-encoded ambler class D beta-lactamase of Shewanella oneidensis as a progenitor of carbapenem-hydrolyzing oxacillinaseQ35006279
Outbreak of carbapenem-resistant Acinetobacter baumannii producing the OXA-23 enzyme in Curitiba, BrazilQ35155708
Acinetobacter spp. as nosocomial pathogens: microbiological, clinical, and epidemiological featuresQ35369996
Genetic environment and transcription of ampC in an Acinetobacter baumannii clinical isolateQ35548390
Genetic and biochemical characterization of a chromosome-encoded carbapenem-hydrolyzing ambler class D beta-lactamase from Shewanella algaeQ37733827
Detection of carbapenemase-producing Acinetobacter baumannii in a hospitalQ39455145
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectAcinetobacter baumanniiQ3241189
carbapenem antibioticQ410897
P1104number of pages7
P304page(s)202-208
P577publication date2005-01-01
P1433published inAntimicrobial Agents and ChemotherapyQ578004
P1476titleOXA-58, a novel class D {beta}-lactamase involved in resistance to carbapenems in Acinetobacter baumannii
P478volume49

Reverse relations

cites work (P2860)
Q37501919"Roar" of blaNDM-1 and "silence" of blaOXA-58 co-exist in Acinetobacter pittii
Q21131125"Stormy waters ahead": global emergence of carbapenemases
Q45182367A nosocomial outbreak of Acinetobacter baumannii isolates expressing the carbapenem-hydrolysing oxacillinase OXA-58.
Q36949527A plasmid-borne blaOXA-58 gene confers imipenem resistance to Acinetobacter baumannii isolates from a Lebanese hospital.
Q96230611A single Proteus mirabilis lineage from human and animal sources: a hidden reservoir of OXA-23 or OXA-58 carbapenemases in Enterobacterales
Q33676136Acinetobacter baumannii increases tolerance to antibiotics in response to monovalent cations
Q37202840Acinetobacter baumannii: an emerging multidrug-resistant threat
Q34795807Acinetobacter baumannii: emergence of a successful pathogen
Q34073932Acinetobacter insertion sequence ISAba11 belongs to a novel family that encodes transposases with a signature HHEK motif
Q34735979Acinetobacter radioresistens as a silent source of carbapenem resistance for Acinetobacter spp.
Q37946953Acinetobacter: a potential reservoir and dispenser for β-lactamases
Q38792886Acquired Class D β-Lactamases
Q40083229Activity of the β-Lactamase inhibitor LN-1-255 against carbapenem-hydrolyzing class D β-lactamases from Acinetobacter baumannii
Q34568784Analysis of antibiotic resistance genes in multidrug-resistant Acinetobacter sp. isolates from military and civilian patients treated at the Walter Reed Army Medical Center
Q37544784Antimicrobial resistance determinants in Acinetobacter baumannii isolates taken from military treatment facilities
Q27024893Antimicrobial resistance in Acinetobacter baumannii: From bench to bedside
Q43010593Antimicrobial susceptibility and beta-lactamase production of selected gram-negative bacilli from two Croatian hospitals: MYSTIC study results
Q41878700Antimicrobial susceptibility profiling and genomic diversity of Acinetobacter baumannii isolates: A study in western Iran
Q26739860Antimicrobials: a global alliance for optimizing their rational use in intra-abdominal infections (AGORA).
Q42110570Biochemical and genetic characterization of carbapenem-hydrolyzing β-lactamase OXA-229 from Acinetobacter bereziniae
Q30235064Biology of Acinetobacter baumannii: Pathogenesis, Antibiotic Resistance Mechanisms, and Prospective Treatment Options
Q38243475Carbapenem resistance in Pseudomonas aeruginosa and Acinetobacter baumannii in the nosocomial setting in Latin America.
Q39361779Carbapenem-resistant Acinetobacter baumannii isolates from Tunisia producing the OXA-58-like carbapenem-hydrolyzing oxacillinase OXA-97.
Q40750806Carbapenem-resistant KPC-2-producing Escherichia coli in a Tel Aviv Medical Center, 2005 to 2008
Q38392082Carbapenemase-producing Gram-negative bacteria: current epidemics, antimicrobial susceptibility and treatment options
Q36967241Carbapenemases: molecular diversity and clinical consequences
Q24685034Carbapenemases: the versatile beta-lactamases
Q42249330Carboxylation and decarboxylation of active site Lys 84 controls the activity of OXA-24 β-lactamase of Acinetobacter baumannii: Raman crystallographic and solution evidence
Q34541346Changing carbapenemase gene pattern in an epidemic multidrug-resistant Acinetobacter baumannii lineage causing multiple outbreaks in central Italy.
Q41853577Characterization of a novel plasmid type and various genetic contexts of bla OXA-58 in Acinetobacter spp. from multiple cities in China
Q41338840Characterization of the carbapenem-hydrolyzing oxacillinase oxa-58 in an Acinetobacter genospecies 3 clinical isolate
Q34077024Characterization of the naturally occurring oxacillinase of Acinetobacter baumannii
Q39683488Class D β-lactamases: are they all carbapenemases?
Q39749477Clinical impact and molecular basis of antimicrobial resistance in non-baumannii Acinetobacter
Q41557857Clonal spread of carbapenem non-susceptible Acinetobacter baumannii in an intensive care unit in a teaching hospital in China
Q43194339Codetection of blaOXA-23-like gene (blaOXA-133) and blaOXA-58 in Acinetobacter radioresistens: report from the SENTRY antimicrobial surveillance program
Q33938042Contribution of acquired carbapenem-hydrolyzing oxacillinases to carbapenem resistance in Acinetobacter baumannii
Q27681472Crystal Structure of Carbapenemase OXA-58 from Acinetobacter baumannii
Q27333834Crystal Structure of OXA-58 with the Substrate-Binding Cleft in a Closed State: Insights into the Mobility and Stability of the OXA-58 Structure
Q24674712Crystal structure of the carbapenemase OXA-24 reveals insights into the mechanism of carbapenem hydrolysis
Q33676198Detection of KPC in Acinetobacter spp. in Puerto Rico
Q64283153Detection of co-harboring OXA-58 and NDM-1 carbapenemase producing genes resided on a same plasmid from an clinical isolate in China
Q38869114Development of a rapid diagnostic assay based on magnetic bead purification of OXA-β-lactamase mRNA.
Q46431902Dissemination of blaOXA-58 in Proteus mirabilis isolates from Germany.
Q37590023Diversity, epidemiology, and genetics of class D beta-lactamases
Q41791384Emergence of KPC-2 and KPC-3 in carbapenem-resistant Klebsiella pneumoniae strains in an Israeli hospital.
Q43152124Emergence of PER-2 and VEB-1a in Acinetobacter baumannii Strains in the Americas.
Q90624686Emergence, molecular mechanisms and global spread of carbapenem-resistant Acinetobacter baumannii
Q41946181Ertapenem resistance among extended-spectrum-beta-lactamase-producing Klebsiella pneumoniae isolates
Q42597325Evidence of diversity among epidemiologically related carbapenemase-producing Acinetobacter baumannii strains belonging to international clonal lineage II.
Q34568285Evolution of a pathogen: a comparative genomics analysis identifies a genetic pathway to pathogenesis in Acinetobacter
Q42576942Extended-spectrum cephalosporinase in Acinetobacter baumannii
Q43703033Fertilizing with Animal Manure Disseminates Antibiotic Resistance Genes to the Farm Environment.
Q43236886First identification of blaOXA-51-like in non-baumannii Acinetobacter spp.
Q37160172First occurrence of bla OXA-58 in Acinetobacter baumannii isolated from a clinical sample in Southern Brazil
Q47166452First report of OXA-143-lactamase producing Acinetobacter baumannii in Qom, Iran
Q57167678First report of colistin resistance among carbapenem-resistant isolates recovered from hospitalized patients in Egypt
Q42408826First report of the carbapenem-hydrolyzing oxacillinase OXA-58 in Acinetobacter baumannii isolates in Italy
Q35032131Genetic acquisition of NDM gene offers sustainability among clinical isolates of Pseudomonas aeruginosa in clinical settings
Q87258595Genetic diversity of OXA-51-like genes among multidrug-resistant Acinetobacter baumannii in Riyadh, Saudi Arabia
Q33770194Genetic environment and expression of the extended-spectrum beta-lactamase blaPER-1 gene in gram-negative bacteria
Q34510657Genetic structures at the origin of acquisition and expression of the carbapenem-hydrolyzing oxacillinase gene blaOXA-58 in Acinetobacter baumannii
Q42846108Genetics and expression of the carbapenem-hydrolyzing oxacillinase gene blaOXA-23 in Acinetobacter baumannii
Q39845137Gut colonization by multidrug-resistant and carbapenem-resistant Acinetobacter baumannii in neonates
Q40575020High prevalence of the PER-1 gene among carbapenem-resistant Acinetobacter baumannii in Riyadh, Saudi Arabia
Q52669151Host range of antibiotic resistance genes in wastewater treatment plant influent and effluent.
Q38795412Hydrolytic mechanism of OXA-58 enzyme, a carbapenem-hydrolyzing class D β-lactamase from Acinetobacter baumannii
Q48081749IMP-4 and OXA beta-lactamases in Acinetobacter baumannii from Singapore
Q34529149ISAba825, a functional insertion sequence modulating genomic plasticity and bla(OXA-58) expression in Acinetobacter baumannii
Q36971091Identification of blaOXA-₅₁-like, blaOXA-₅₈, blaDIM-₁, and blaVIM carbapenemase genes in hospital Enterobacteriaceae isolates from Sierra Leone
Q35840875Identification of the novel narrow-spectrum beta-lactamase SCO-1 in Acinetobacter spp. from Argentina
Q90391781Identifying Oxacillinase-48 Carbapenemase Inhibitors Using DNA-Encoded Chemical Libraries
Q42594626Imipenem-resistant Acinetobacter baumannii carrying the ISAba1-bla OXA-23,51 and ISAba1-bla ADC-7 genes in Monteria, Colombia
Q42056806In vivo selection of reduced susceptibility to carbapenems in Acinetobacter baumannii related to ISAba1-mediated overexpression of the natural bla(OXA-66) oxacillinase gene
Q28078376Insights on the Horizontal Gene Transfer of Carbapenemase Determinants in the Opportunistic Pathogen Acinetobacter baumannii
Q38086337Investigation of antibiotic resistance in the genomic era of multidrug-resistant Gram-negative bacilli, especially Enterobacteriaceae, Pseudomonas and Acinetobacter
Q79364706Low genetic diversity of the intrinsic OXA-51-like class D carbapenemases among Acinetobacter baumannii clinical isolates in Greece
Q39900310Molecular characterization of acinetobacter isolates collected in intensive care units of six hospitals in Florence, Italy, during a 3-year surveillance program: a population structure analysis
Q38672110Molecular epidemiology of carbapenem-resistant Acinetobacter baumannii in Greece: an extended review (2000-2015).
Q44290539Molecular epidemiology of carbapenem-resistant Acinetobacter spp. from XiangYa Hospital, in Hunan Province, China
Q41818312Multicopy blaOXA-58 gene as a source of high-level resistance to carbapenems in Acinetobacter baumannii
Q44724694New eight genes identified at the clinical multidrug-resistant Acinetobacter baumannii DMS06669 strain in a Vietnam hospital
Q38201699OXA β-lactamases
Q42363548OXA-134, a naturally occurring carbapenem-hydrolyzing class D beta-lactamase from Acinetobacter lwoffii
Q37450717OXA-143, a novel carbapenem-hydrolyzing class D beta-lactamase in Acinetobacter baumannii
Q35270559OXA-198, an acquired carbapenem-hydrolyzing class D beta-lactamase from Pseudomonas aeruginosa
Q28286208OXA-235, a novel class D β-lactamase involved in resistance to carbapenems in Acinetobacter baumannii
Q40781496OXA-372, a novel carbapenem-hydrolysing class D β-lactamase from a Citrobacter freundii isolated from a hospital wastewater plant
Q43181826OXA-58 and IMP-4 carbapenem-hydrolyzing beta-lactamases in an Acinetobacter junii blood culture isolate from Australia
Q36381840OXA-type carbapenemases
Q34352265Occurrence of OXA-58-like carbapenemases in Acinetobacter spp. collected over 10 years in three continents
Q34042432Outbreak of carbapenem-resistant Acinetobacter baumannii producing the carbapenemase OXA-23 in a tertiary care hospital of Papeete, French Polynesia
Q34564018Outbreak of infection by carbapenem-resistant Acinetobacter baumannii producing the carbapenemase OXA-58 in Belgium
Q46907740Outbreak of multiple clones of imipenem-resistant Acinetobacter baumannii isolates expressing OXA-58 carbapenemase in an intensive care unit
Q37485601Outbreaks of imipenem resistant Acinetobacter baumannii producing OXA-23 beta-lactamase in a tertiary care hospital in Korea
Q42142530Phenotypic, biochemical, and molecular techniques for detection of metallo-β-lactamase NDM in Acinetobacter baumannii
Q92127120Proteus mirabilis Producing the OXA-58 Carbapenemase in Poland
Q53291076Quantitative Proteomic Analysis of Cell Wall and Plasma Membrane Fractions from Multidrug-Resistant Acinetobacter baumannii
Q34042289Regional occurrence of plasmid-mediated carbapenem-hydrolyzing oxacillinase OXA-58 in Acinetobacter spp. in Europe
Q37204254Resistance plasmid families in Enterobacteriaceae
Q40646621Spread of carbapenem-resistant international clones of Acinetobacter baumannii in Turkey and Azerbaijan: a collaborative study.
Q37625333Spread of the blaOXA-23-Containing Tn2008 in Carbapenem-Resistant Acinetobacter baumannii Isolates Grouped in CC92 from China
Q37879199Status report on carbapenemases: challenges and prospects
Q27679881Structural Basis for Carbapenemase Activity of the OXA-23 β-Lactamase from Acinetobacter baumannii
Q35987600Structural Basis for Enhancement of Carbapenemase Activity in the OXA-51 Family of Class D β-Lactamases
Q28084628Structural basis for carbapenem-hydrolyzing mechanisms of carbapenemases conferring antibiotic resistance
Q35905605The Acinetobacter baumannii Oxymoron: Commensal Hospital Dweller Turned Pan-Drug-Resistant Menace
Q37608564The different inhibition mechanisms of OXA-1 and OXA-24 β-lactamases are determined by the stability of active site carboxylated lysine
Q40424743The epidemiology of carbapenemases in Latin America and the Caribbean
Q39240966The impact of insertion sequences on bacterial genome plasticity and adaptability.
Q35794409The role of vancomycin in addition with colistin and meropenem against colistin-sensitive multidrug resistant Acinetobacter baumannii causing severe infections in a Paediatric Intensive Care Unit
Q27666064Three factors that modulate the activity of class D β-lactamases and interfere with the post-translational carboxylation of Lys70
Q41808243VIM-1 metallo-beta-lactamase in Acinetobacter baumannii
Q36744796Whole-genome pyrosequencing of an epidemic multidrug-resistant Acinetobacter baumannii strain belonging to the European clone II group

Search more.