scholarly article | Q13442814 |
review article | Q7318358 |
P6179 | Dimensions Publication ID | 1003142349 |
P356 | DOI | 10.1007/S00253-010-2578-3 |
P932 | PMC publication ID | 2872025 |
P698 | PubMed publication ID | 20396881 |
P5875 | ResearchGate publication ID | 43161372 |
P50 | author | Heinz Neumann | Q56843267 |
P2093 | author name string | Petra Neumann-Staubitz | |
P2860 | cites work | Functional coupling of mammalian receptors to the yeast mating pathway using novel yeast/mammalian G protein alpha-subunit chimeras | Q73323750 |
Creating bacterial strains from genomes that have been cloned and engineered in yeast | Q84441441 | ||
Production of the antimalarial drug precursor artemisinic acid in engineered yeast | Q22061873 | ||
One-step assembly in yeast of 25 overlapping DNA fragments to form a complete synthetic Mycoplasma genitalium genome | Q22066288 | ||
Combination bacteriolytic therapy for the treatment of experimental tumors | Q24555050 | ||
Expression in Escherichia coli of chemically synthesized genes for human insulin | Q24599184 | ||
Structural basis for the promiscuous biosynthetic prenylation of aromatic natural products | Q24608866 | ||
GenBank | Q24656173 | ||
Environmental signal integration by a modular AND gate | Q24670375 | ||
Solution structure and proposed domain-domain recognition interface of an acyl carrier protein domain from a modular polyketide synthase | Q27648476 | ||
Kemp elimination catalysts by computational enzyme design | Q27650119 | ||
Lysine acetylation targets protein complexes and co-regulates major cellular functions | Q27860589 | ||
Catalytic promiscuity and the evolution of new enzymatic activities | Q28140063 | ||
An expanded eukaryotic genetic code | Q28201981 | ||
Engineering a mevalonate pathway in Escherichia coli for production of terpenoids | Q28207854 | ||
Expanding the genetic code of Escherichia coli | Q28213675 | ||
Enzymatic assembly of DNA molecules up to several hundred kilobases | Q28241142 | ||
Fluorescent indicators for Ca2+ based on green fluorescent proteins and calmodulin | Q28247685 | ||
Programming cells by multiplex genome engineering and accelerated evolution | Q28253066 | ||
Substrate and functional diversity of lysine acetylation revealed by a proteomics survey | Q28258445 | ||
Complete chemical synthesis, assembly, and cloning of a Mycoplasma genitalium genome | Q28265807 | ||
Encoding multiple unnatural amino acids via evolution of a quadruplet-decoding ribosome | Q28273162 | ||
Synthetic biology: engineering Escherichia coli to see light | Q28283472 | ||
Environmentally controlled invasion of cancer cells by engineered bacteria | Q28285227 | ||
Protein-based organelles in bacteria: carboxysomes and related microcompartments | Q28289715 | ||
Mono- and sesquiterpenes and antifungal constituents from Artemisia species | Q28371893 | ||
Total Synthesis of Anticancer Agent Taxol Achieved by Two Different Routes | Q29027286 | ||
The structure of a ketoreductase determines the organization of the beta-carbon processing enzymes of modular polyketide synthases. | Q45952293 | ||
Genetic encoding and labeling of aliphatic azides and alkynes in recombinant proteins via a pyrrolysyl-tRNA Synthetase/tRNA(CUA) pair and click chemistry. | Q45974834 | ||
Microbial sensors for small molecules: development of a mevalonate biosensor | Q46076042 | ||
Engineering Escherichia coli for production of functionalized terpenoids using plant P450s | Q46094196 | ||
A novel semi-biosynthetic route for artemisinin production using engineered substrate-promiscuous P450(BM3). | Q46094956 | ||
High-level production of amorpha-4,11-diene in a two-phase partitioning bioreactor of metabolically engineered Escherichia coli | Q46213323 | ||
Genetically selected cyclic-peptide inhibitors of AICAR transformylase homodimerization | Q46437752 | ||
Recombinant expression of selectively sulfated proteins in Escherichia coli | Q46578070 | ||
Heterologous production of epothilone C and D in Escherichia coli. | Q46609321 | ||
Genetic engineering of taxol biosynthetic genes in Saccharomyces cerevisiae | Q46701927 | ||
Genetically encoding N(epsilon)-acetyllysine in recombinant proteins. | Q46751659 | ||
Combinatorial polyketide biosynthesis by de novo design and rearrangement of modular polyketide synthase genes. | Q46832912 | ||
Genetic incorporation of unnatural amino acids into proteins in mammalian cells | Q46866635 | ||
Programmed population control by cell-cell communication and regulated killing. | Q51693435 | ||
Controlling gene expression in living cells through small molecule-RNA interactions. | Q54122320 | ||
Evolved orthogonal ribosomes enhance the efficiency of synthetic genetic code expansion. | Q54439095 | ||
Functional aptamers and aptazymes in biotechnology, diagnostics, and therapy | Q36917651 | ||
Lysine acetylation is a highly abundant and evolutionarily conserved modification in Escherichia coli | Q37080670 | ||
Engineered biosynthesis of bacterial aromatic polyketides in Escherichia coli | Q37081542 | ||
De novo biosynthetic pathways: rational design of microbial chemical factories | Q37251461 | ||
Engineering the Salmonella type III secretion system to export spider silk monomers | Q37379494 | ||
Revisiting the modularity of modular polyketide synthases | Q37393154 | ||
De novo design of catalytic proteins | Q37415513 | ||
Green light to illuminate signal transduction events. | Q37439970 | ||
Computational design tools for synthetic biology | Q37598457 | ||
Emerging applications of riboswitches in chemical biology | Q37668585 | ||
Engineering signal transduction pathways | Q37677850 | ||
Use of two-component signal transduction systems in the construction of synthetic genetic networks | Q37690978 | ||
Functional coupling of a mammalian somatostatin receptor to the yeast pheromone response pathway. | Q38289907 | ||
Tetracycline-aptamer-mediated translational regulation in yeast | Q38350910 | ||
Conditional gene expression by controlling translation with tetracycline-binding aptamers | Q38356395 | ||
Genetically engineered Salmonella typhimurium as an imageable therapeutic probe for cancer | Q39760012 | ||
Next-generation synthetic gene networks | Q39919274 | ||
A method for genetically installing site-specific acetylation in recombinant histones defines the effects of H3 K56 acetylation | Q40097842 | ||
Engineering Escherichia coli for the synthesis of taxadiene, a key intermediate in the biosynthesis of taxol | Q40686859 | ||
A theophylline responsive riboswitch based on helix slipping controls gene expression in vivo | Q40773171 | ||
Eleutherobin, a novel cytotoxic agent that induces tubulin polymerization, is similar to paclitaxel (Taxol). | Q41056495 | ||
Clinical overview of the taxanes. | Q41606989 | ||
Improving lycopene production in Escherichia coli by engineering metabolic control | Q41734961 | ||
Synthetic biology: promises and challenges | Q42919282 | ||
Genetically encoding N(epsilon)-methyl-L-lysine in recombinant histones. | Q43273104 | ||
Production of ansamycin polyketide precursors in Escherichia coli | Q43718451 | ||
A simple conversion of artemisinic acid into artemisinin | Q43863386 | ||
In vivo imaging of the dynamics of glucose uptake in the cytosol of COS-7 cells by fluorescent nanosensors | Q44370241 | ||
Analysis of underivatized amino acids and their D/L-enantiomers by sheathless capillary electrophoresis/electrospray ionization mass spectrometry | Q44377902 | ||
Inhibition of HIV budding by a genetically selected cyclic peptide targeting the Gag-TSG101 interaction | Q44447645 | ||
Understanding substrate specificity of polyketide synthase modules by generating hybrid multimodular synthases. | Q44552141 | ||
Pilot trial of genetically modified, attenuated Salmonella expressing the E. coli cytosine deaminase gene in refractory cancer patients | Q44591603 | ||
A chemical toolkit for proteins--an expanded genetic code | Q44801045 | ||
Site-specific PEGylation of proteins containing unnatural amino acids | Q45121216 | ||
Functional expression of olfactory receptors in yeast and development of a bioassay for odorant screening | Q45227547 | ||
Radio-responsive recA promoter significantly increases TNFalpha production in recombinant clostridia after 2 Gy irradiation | Q45879277 | ||
Computational design of receptor and sensor proteins with novel functions | Q30332826 | ||
Production of cyclic peptides and proteins in vivo | Q30816360 | ||
Identification of allosteric peptide agonists of CXCR4. | Q30868390 | ||
Taxol biosynthetic genes | Q31004828 | ||
A systematic method for identifying small-molecule modulators of protein-protein interactions | Q31122646 | ||
A method for the generation of glycoprotein mimetics | Q31131271 | ||
Biosynthesis of complex polyketides in a metabolically engineered strain of E. coli | Q32075037 | ||
Tuning genetic control through promoter engineering | Q33222305 | ||
Synthetic promoter libraries--tuning of gene expression | Q33231382 | ||
Genome-wide high-throughput mining of natural-product biosynthetic gene clusters by phage display | Q33279697 | ||
Combinatorial biosynthesis for drug development | Q33286975 | ||
Discovery of antibacterial cyclic peptides that inhibit the ClpXP protease | Q33289276 | ||
Manipulation and potentiation of antimycobacterial immunity using recombinant bacille Calmette-Guérin strains that secrete cytokines | Q33591159 | ||
Macromolecular compartmentation and channeling. | Q33769793 | ||
Designed divergent evolution of enzyme function | Q33993746 | ||
Visualization of maltose uptake in living yeast cells by fluorescent nanosensors. | Q34075946 | ||
Process and metabolic strategies for improved production of Escherichia coli-derived 6-deoxyerythronolide B. | Q34101057 | ||
Engineered biosynthesis of aklanonic acid analogues | Q34293749 | ||
Programmable cells: interfacing natural and engineered gene networks | Q34322635 | ||
Taxol: biosynthesis, molecular genetics, and biotechnological applications | Q34427992 | ||
Genome transplantation in bacteria: changing one species to another | Q34643428 | ||
The chemistry of taxol and related taxoids | Q34753279 | ||
Metabolic engineering of taxadiene biosynthesis in yeast as a first step towards Taxol (Paclitaxel) production | Q34779126 | ||
Synthetic protein scaffolds provide modular control over metabolic flux. | Q34995237 | ||
The 2.7-Angstrom crystal structure of a 194-kDa homodimeric fragment of the 6-deoxyerythronolide B synthase. | Q35131209 | ||
Bacteria as tumour-targeting vectors | Q35215803 | ||
The use of live attenuated bacteria as a delivery system for heterologous antigens | Q35809240 | ||
Engineered biosynthesis of an ansamycin polyketide precursor in Escherichia coli. | Q35813522 | ||
Periplasmic binding proteins: a versatile superfamily for protein engineering | Q35863927 | ||
Prenylated flavonoids: pharmacology and biotechnology | Q36079822 | ||
Round and round we go: cyclic peptides in disease | Q36569984 | ||
Genetic parts to program bacteria | Q36595370 | ||
Construction of a fluorescent biosensor family | Q36639569 | ||
Application of functional genomics to pathway optimization for increased isoprenoid production. | Q36672684 | ||
P433 | issue | 1 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | biotechnology | Q7108 |
synthetic biology | Q862838 | ||
drug discovery | Q1418791 | ||
bacteria | Q10876 | ||
biomedical investigative technique | Q66648976 | ||
P304 | page(s) | 75-86 | |
P577 | publication date | 2010-04-16 | |
2010-06-01 | |||
P1433 | published in | Applied Microbiology and Biotechnology | Q13553694 |
P1476 | title | Synthetic biology approaches in drug discovery and pharmaceutical biotechnology | |
P478 | volume | 87 |
Q90253504 | An integrated bacterial system for the discovery of chemical rescuers of disease-associated protein misfolding |
Q35224044 | Artificially constructed quorum-sensing circuits are used for subtle control of bacterial population density |
Q28079519 | CRISPR-Cas9: Tool for Qualitative and Quantitative Plant Genome Editing |
Q33638221 | Catalytic Upgrading in Bacteria-Compatible Conditions via a Biocompatible Aldol Condensation. |
Q38994624 | Challenges for the European governance of synthetic biology for human health |
Q99731145 | Current approaches for target-specific drug discovery using natural compounds against SARS-CoV-2 infection |
Q46714174 | Databases of the thiotemplate modular systems (CSDB) and their in silico recombinants (r-CSDB). |
Q34215866 | Directed evolution as a powerful synthetic biology tool |
Q28080553 | Emerging concepts promising new horizons for marine biodiscovery and synthetic biology |
Q28646468 | Establishing Chlamydomonas reinhardtii as an industrial biotechnology host |
Q61983517 | Metagenomics as a Tool for Biodiscovery and Enhanced Production of Marine Bioactives |
Q51115409 | Opportunities in plant synthetic biology. |
Q38954652 | Pathway Design, Engineering, and Optimization |
Q42728840 | Synergistic Synthetic Biology: Units in Concert |
Q34675593 | Synthetic biology: putting synthesis into biology |
Q28706666 | Synthetic genomics and synthetic biology applications between hopes and concerns |
Q38153035 | Systems approaches for synthetic biology: a pathway toward mammalian design |
Q34258777 | Unexploited therapies in breast and prostate cancer: blockade of the prolactin receptor |
Q34459997 | mRNA display selection and solid-phase synthesis of Fc-binding cyclic peptide affinity ligands |
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