Conversion of encapsulated 5-fluoro-2'-deoxyuridine 5'-monophosphate to the antineoplastic drug 5-fluoro-2'-deoxyuridine in human erythrocytes

scientific article

Conversion of encapsulated 5-fluoro-2'-deoxyuridine 5'-monophosphate to the antineoplastic drug 5-fluoro-2'-deoxyuridine in human erythrocytes is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1073/PNAS.85.9.3145
P932PMC publication ID280160
P698PubMed publication ID2966399
P5875ResearchGate publication ID20190660

P2093author name stringDe Flora A
Guida L
Zocchi E
Benatti U
Polvani C
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Phase I study of 5-fluorodeoxyuridine plus cytosine arabinoside infusions in patients with solid tumorsQ39892748
Encapsulation of exogenous agents in erythrocytes and the circulating survival of carrier erythrocytesQ40214899
Characteristics of a pyrimidine-specific 5'-nucleotidase in human erythrocytesQ40343321
In vitro correction of erythrocyte glucose 6-phosphate dehydrogenase (G6PD) deficiencyQ41128733
High-yield entrapment of proteins into erythrocytesQ41326312
Construction of glucose oxidase-loaded human erythrocytes: a model of oxidative cytotoxicity.Q43840706
The removal of leukocytes and platelets from whole blood.Q44677074
A prospective phase II clinical trial of continuous FUDR regional chemotherapy for colorectal metastases to the liver using a totally implantable drug infusion pump.Q52700835
Nucleoside transport in human erythrocytes. A simple carrier with directional symmetry and differential mobility of loaded and empty carrier.Q52713959
Physiological effects of high-P50 erythrocyte transfusion on piglets.Q53680867
Hepatic or splenic targeting of carrier erythrocytes: a murine modelQ69440231
Large-scale entrapment of drugs into resealed red blood cells using a continuous-flow dialysis systemQ69480253
Osmotic fragility of drug carrier erythrocytesQ70054182
Hepatic pharmacokinetics of glutaraldehyde-treated methotrexate-loaded carrier erythrocytes in dogsQ70457011
Circulating carrier erythrocytes: slow-release vehicle for an antileukemic drug, cytosine arabinosideQ70575637
Morphological alterations of red blood cells in favism. A study with Nomarski optics and electron microscopyQ70598219
Glutaraldehyde-treated carrier erythrocytes for organ targeting of methotrexate in dogsQ71593566
Resealed red blood cells as a new blood transfusion productQ93568216
Incorporation of allosteric effectors of hemoglobin in red blood cells. Physiological effectsQ93568223
P433issue9
P407language of work or nameEnglishQ1860
P921main subjectfloxuridineQ5462356
human erythrocyteQ111535219
P304page(s)3145-3149
P577publication date1988-05-01
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleConversion of encapsulated 5-fluoro-2'-deoxyuridine 5'-monophosphate to the antineoplastic drug 5-fluoro-2'-deoxyuridine in human erythrocytes
P478volume85

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cites work (P2860)
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Q90524204Erythrocytes as Carriers: From Drug Delivery to Biosensors
Q37707194Formulation and Drug Loading Features of Nano-Erythrocytes.
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Q24528271Homogeneous pyrimidine nucleotidase from human erythrocytes: enzymic and molecular properties
Q67478665Interactions of Carboplatin with Human Erythrocytes and Murine Erythroleukemic Cells
Q36994110Polymeric nanogels containing the triphosphate form of cytotoxic nucleoside analogues show antitumor activity against breast and colorectal cancer cell lines
Q24320120Pyrimidine nucleotidases from human erythrocyte possess phosphotransferase activities specific for pyrimidine nucleotides
Q37638602Synthesis and targeted delivery of an azidothymidine homodinucleotide conferring protection to macrophages against retroviral infection.

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