scholarly article | Q13442814 |
P50 | author | Motofumi Tanaka | Q90953497 |
Milind Javle | Q92719947 | ||
Donghui Li | Q112692814 | ||
James Lewis Abbruzzese | Q14947937 | ||
P2093 | author name string | Taro Okazaki | |
P2860 | cites work | Gemcitabine: a modulator of intracellular nucleotide and deoxynucleotide metabolism | Q71542211 |
Pharmacokinetics of gemcitabine in Japanese cancer patients: the impact of a cytidine deaminase polymorphism | Q79460532 | ||
Thirty novel genetic variations in the SLC29A1 gene encoding human equilibrative nucleoside transporter 1 (hENT1) | Q79955361 | ||
Gemcitabine pharmacogenomics: cytidine deaminase and deoxycytidylate deaminase gene resequencing and functional genomics | Q82903101 | ||
Resistance to gemcitabine in a human follicular lymphoma cell line is due to partial deletion of the deoxycytidine kinase gene | Q24794747 | ||
Human equilibrative nucleoside transporter 1 levels predict response to gemcitabine in patients with pancreatic cancer. | Q27863396 | ||
Assessing the probability that a positive report is false: an approach for molecular epidemiology studies | Q29616285 | ||
A "silent" polymorphism in the MDR1 gene changes substrate specificity | Q29619435 | ||
Gemcitabine chemoresistance and molecular markers associated with gemcitabine transport and metabolism in human pancreatic cancer cells | Q29937967 | ||
Transcription analysis of human equilibrative nucleoside transporter-1 predicts survival in pancreas cancer patients treated with gemcitabine. | Q33238550 | ||
Severe drug toxicity associated with a single-nucleotide polymorphism of the cytidine deaminase gene in a Japanese cancer patient treated with gemcitabine plus cisplatin | Q33365727 | ||
Cellular pharmacology of gemcitabine | Q34542801 | ||
Determinants of resistance to 2',2'-difluorodeoxycytidine (gemcitabine). | Q34750366 | ||
Molecular biomarkers: their increasing role in the diagnosis, characterization, and therapy guidance in pancreatic cancer. | Q36464111 | ||
Pharmacogenomics of gemcitabine: can genetic studies lead to tailor-made therapy? | Q36610851 | ||
Significant associations of mismatch repair gene polymorphisms with clinical outcome of pancreatic cancer | Q37158252 | ||
Preoperative gemcitabine and cisplatin followed by gemcitabine-based chemoradiation for resectable adenocarcinoma of the pancreatic head | Q40068712 | ||
Gemcitabine resistance due to deoxycytidine kinase deficiency can be reverted by fruitfly deoxynucleoside kinase, DmdNK, in human uterine sarcoma cells | Q40319699 | ||
Determinants of sensitivity and resistance to gemcitabine: the roles of human equilibrative nucleoside transporter 1 and deoxycytidine kinase in non-small cell lung cancer | Q40506711 | ||
Pretreatment deoxycytidine kinase levels predict in vivo gemcitabine sensitivity. | Q44245520 | ||
A functional single-nucleotide polymorphism in the human cytidine deaminase gene contributing to ara-C sensitivity. | Q44289169 | ||
Identification and analysis of single-nucleotide polymorphisms in the gemcitabine pharmacologic pathway | Q44956846 | ||
The absence of human equilibrative nucleoside transporter 1 is associated with reduced survival in patients with gemcitabine-treated pancreas adenocarcinoma. | Q45122012 | ||
Association between single nucleotide polymorphisms in deoxycytidine kinase and treatment response among acute myeloid leukaemia patients | Q45163411 | ||
Functional characterization in yeast of genetic variants in the human equilibrative nucleoside transporter, ENT1 | Q46042363 | ||
Preoperative gemcitabine-based chemoradiation for patients with resectable adenocarcinoma of the pancreatic head | Q46473461 | ||
Functional single nucleotide polymorphism haplotypes in the human equilibrative nucleoside transporter 1. | Q46491555 | ||
Identification of functional single nucleotide polymorphism haplotypes in the cytidine deaminase promoter | Q46919608 | ||
Structural and functional analysis of the cytidine deaminase gene in patients with acute myeloid leukaemia. | Q54109043 | ||
Preoperative chemoradiation and pancreaticoduodenectomy for adenocarcinoma of the pancreas | Q67523718 | ||
2'-Deoxy-2'-methylenecytidine and 2'-deoxy-2',2'-difluorocytidine 5'-diphosphates: potent mechanism-based inhibitors of ribonucleotide reductase | Q70215052 | ||
P433 | issue | 1 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | pancreatic cancer | Q212961 |
single-nucleotide polymorphism | Q501128 | ||
P304 | page(s) | 320-329 | |
P577 | publication date | 2009-12-22 | |
P1433 | published in | Clinical Cancer Research | Q332253 |
P1476 | title | Single nucleotide polymorphisms of gemcitabine metabolic genes and pancreatic cancer survival and drug toxicity | |
P478 | volume | 16 |
Q36600132 | A replication study and genome-wide scan of single-nucleotide polymorphisms associated with pancreatic cancer risk and overall survival |
Q53266946 | ATP assay-guided chemosensitivity testing for gemcitabine with biopsy specimens obtained from unresectable pancreatic cancer using endoscopic ultrasonography-guided fine-needle aspiration. |
Q38075827 | Adjuvant pharmacotherapy in the management of elderly patients with pancreatic cancer |
Q48257252 | An A/C germline single-nucleotide polymorphism in the TNFAIP3 gene is associated with advanced disease stage and survival in only surgically treated esophageal cancer. |
Q28076342 | An Overview of Genetic Changes and Risk of Pancreatic Ductal Adenocarcinoma |
Q42725709 | Association between DNA-repair polymorphisms and survival in pancreatic cancer patients treated with combination chemotherapy. |
Q40633085 | Association of genetic polymorphisms with survival of pancreatic ductal adenocarcinoma patients |
Q34474400 | Association of multi‐drug resistance gene polymorphisms with pancreatic cancer outcome |
Q35715498 | Chemotherapy outcomes for the treatment of unresectable intrahepatic and hilar cholangiocarcinoma: a retrospective analysis. |
Q47803255 | Chemotherapy-induced neutropenia and the prognosis of colorectal cancer: a meta-analysis of cohort studies |
Q50659752 | Chemotherapy-induced neutropenia as a prognostic factor in patients with metastatic pancreatic cancer treated with gemcitabine. |
Q38747834 | Cytidine Deaminase Deficiency Reveals New Therapeutic Opportunities against Cancer |
Q44546647 | Cytidine deaminase single-nucleotide polymorphism is predictive of toxicity from gemcitabine in patients with pancreatic cancer: RTOG 9704. |
Q47129097 | DCK expression, a potential predictive biomarker in the adjuvant gemcitabine chemotherapy for biliary tract cancer after surgical resection: results from a phase II study |
Q35584339 | DNA mismatch repair gene polymorphisms affect survival in pancreatic cancer |
Q54494355 | Effect of genetic polymorphisms on therapeutic response and clinical outcomes in pancreatic cancer patients treated with gemcitabine. |
Q36342657 | Enhancing Drug Efficacy and Therapeutic Index through Cheminformatics-Based Selection of Small Molecule Binary Weapons That Improve Transporter-Mediated Targeting: A Cytotoxicity System Based on Gemcitabine |
Q37876401 | Ethnic differences in the metabolism, toxicology and efficacy of three anticancer drugs |
Q34254837 | Gemcitabine metabolic and transporter gene polymorphisms are associated with drug toxicity and efficacy in patients with locally advanced pancreatic cancer |
Q34408283 | Gemcitabine-based chemoradiotherapy followed by surgery for borderline resectable and locally unresectable pancreatic ductal adenocarcinoma: significance of the CA19-9 reduction rate and intratumoral human equilibrative nucleoside transporter 1 expr |
Q35048269 | Genetic effects and modifiers of radiotherapy and chemotherapy on survival in pancreatic cancer |
Q38805564 | Genetic polymorphisms associated with pancreatic cancer survival: a genome-wide association study. |
Q28943489 | Genome-wide association study of survival in patients with pancreatic adenocarcinoma |
Q45220444 | Genomic polymorphisms of SLC29A3 associated with overall survival in advanced non-small-cell lung cancer treated with gemcitabine |
Q42486793 | Heme oxygenase-1 germ line GTn promoter polymorphism is an independent prognosticator of tumor recurrence and survival in pancreatic cancer |
Q38698643 | Human Concentrative Nucleoside Transporter 3 (hCNT3, SLC28A3) Forms a Cyclic Homotrimer. |
Q37342736 | Human Equilibrative Nucleoside Transporter 1 (hENT1) in Pancreatic Adenocarcinoma: Towards Individualized Treatment Decisions. |
Q47102782 | Impact of Polymorphic Variations of Gemcitabine Metabolism, DNA Damage Repair, and Drug-Resistance Genes on the Effect of High-Dose Chemotherapy for Relapsed or Refractory Lymphoid Malignancies |
Q53653257 | Impact of single nucleotide polymorphisms of cytarabine metabolic genes on drug toxicity in childhood acute lymphoblastic leukemia. |
Q83389944 | Integrating pharmacogenetics into gemcitabine dosing--time for a change? |
Q39250668 | Molecular predictors of gemcitabine response in pancreatic cancer |
Q38842938 | Nucleoside analogs: ready to enter the era of precision medicine? |
Q35066350 | Nucleoside transporter proteins as biomarkers of drug responsiveness and drug targets. |
Q49387560 | Overcoming tumor cell chemoresistance using nanoparticles: lysosomes are beneficial for (stearoyl) gemcitabine-incorporated solid lipid nanoparticles |
Q38067828 | Pancreatic cancer - cost for overtreatment with gemcitabine. |
Q54494358 | Pathway-based pharmacogenomics of gemcitabine pharmacokinetics in patients with solid tumors. |
Q42130469 | Patient-Specific Pluripotent Stem Cells in Doxorubicin Cardiotoxicity: A New Window Into Personalized Medicine |
Q36097060 | Personalized therapy for pancreatic cancer: Myth or reality in 2010? |
Q38003703 | Pharmacogenetics of chemotherapy efficacy in breast cancer |
Q30728815 | Pharmacogenomic characterization of gemcitabine response--a framework for data integration to enable personalized medicine |
Q38596926 | Pharmacogenomics in the treatment of lung cancer: an update |
Q26752368 | Pharmacokinetics and pharmacogenetics of Gemcitabine as a mainstay in adult and pediatric oncology: an EORTC-PAMM perspective |
Q41836511 | Preoperative therapies for resectable and borderline resectable pancreatic cancer |
Q36003248 | Ribonucleotide reductase M2 does not predict survival in patients with resectable pancreatic adenocarcinoma |
Q38236028 | Role of solute carrier transporters in pancreatic cancer: a review |
Q50053693 | Severe acute toxicity following gemcitabine administration: A report of four cases with cytidine deaminase polymorphisms evaluation |
Q49997308 | Stemness and anti-cancer drug resistance in ATP-binding cassette subfamily G member 2 highly expressed pancreatic cancer is induced in 3D culture conditions. |
Q27021716 | Systemic therapies for pancreatic cancer--the role of pharmacogenetics |
Q36525188 | Targeting ATR in vivo using the novel inhibitor VE-822 results in selective sensitization of pancreatic tumors to radiation. |
Q28550040 | The Metastatic Potential and Chemoresistance of Human Pancreatic Cancer Stem Cells |
Q43631694 | The association between neutropenia and prognosis in stage III colorectal cancer patients receiving adjuvant chemotherapy |
Q37663396 | Uptake carriers and oncology drug safety |
Q60957982 | Use of Germline Genetic Variability for Prediction of Chemoresistance and Prognosis of Breast Cancer Patients |
Q37207004 | dCK Expression and Gene Polymorphism With Gemcitabine Chemosensitivity in Patients With Pancreatic Ductal Adenocarcinoma: A Strobe-Compliant Observational Study |
Q26862139 | hENT1 expression is predictive of gemcitabine outcome in pancreatic cancer: a systematic review |