scholarly article | Q13442814 |
review article | Q7318358 |
P6179 | Dimensions Publication ID | 1039149383 |
P356 | DOI | 10.1007/S10555-010-9224-5 |
P932 | PMC publication ID | 4012531 |
P698 | PubMed publication ID | 20393783 |
P50 | author | Amato J. Giaccia | Q110591782 |
P2093 | author name string | Elizabeth C Finger | |
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Lysyl oxidase mediates hypoxic control of metastasis | Q28271667 | ||
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Inactivation of the lysyl oxidase gene Lox leads to aortic aneurysms, cardiovascular dysfunction, and perinatal death in mice | Q28510969 | ||
Fully processed lysyl oxidase catalyst translocates from the extracellular space into nuclei of aortic smooth-muscle cells | Q28568824 | ||
Metalloproteinase Activity Secreted by Fibrogenic Cells in the Processing of Prolysyl Oxidase | Q29544584 | ||
Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis | Q29547178 | ||
Normalization of tumor vasculature: an emerging concept in antiangiogenic therapy | Q29547379 | ||
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Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis | Q29617644 | ||
Stromal fibroblasts in cancer initiation and progression | Q29618873 | ||
Basement membranes: structure, assembly and role in tumour angiogenesis | Q29622882 | ||
An overview of epithelio-mesenchymal transformation | Q30014826 | ||
Matrix metalloproteinases: a tail of a frog that became a prince | Q33337157 | ||
Measurement of matrix metalloproteinases and tissue inhibitors of metalloproteinases in blood and tissues. Clinical and experimental applications | Q33692926 | ||
Infections as a major preventable cause of human cancer | Q33916455 | ||
The modular architecture of a new family of growth regulators related to connective tissue growth factor | Q34306420 | ||
Hypoxia, melanocytes and melanoma - survival and tumor development in the permissive microenvironment of the skin | Q34570988 | ||
Snail regulates cell-matrix adhesion by regulation of the expression of integrins and basement membrane proteins. | Q35676694 | ||
Volociximab, a chimeric monoclonal antibody that specifically binds alpha5beta1 integrin: a phase I, pharmacokinetic, and biological correlative study | Q36087887 | ||
Recombinant human erythropoietin in oncology: current status and further developments | Q36164274 | ||
The fallacy of epithelial mesenchymal transition in neoplasia | Q36197878 | ||
Ultrastructural immunolocalization of lysyl oxidase in vascular connective tissue | Q36215340 | ||
Matrix metalloproteinases: role in arthritis | Q36251020 | ||
Correlation between the tumoral expression of beta3-integrin and outcome in cervical cancer patients who had undergone radiotherapy | Q36615716 | ||
Hyperbaric oxygen therapy for malignancy: a review. | Q36653195 | ||
Hypoxia, gene expression, and metastasis | Q36801457 | ||
Prevention of hypoxia by myoglobin expression in human tumor cells promotes differentiation and inhibits metastasis | Q37143367 | ||
Genome-wide association of hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha DNA binding with expression profiling of hypoxia-inducible transcripts | Q37285034 | ||
Validation of lysyl oxidase as a prognostic marker for metastasis and survival in head and neck squamous cell carcinoma: Radiation Therapy Oncology Group trial 90-03. | Q37347497 | ||
The role of tumor cell-derived connective tissue growth factor (CTGF/CCN2) in pancreatic tumor growth | Q37353804 | ||
Prostate cancer specific integrin alphavbeta3 modulates bone metastatic growth and tissue remodeling | Q37365541 | ||
EMT, the cytoskeleton, and cancer cell invasion | Q37377630 | ||
Matrix metalloproteinases as novel biomarkers and potential therapeutic targets in human cancer | Q37412311 | ||
Role of hypoxia in the hallmarks of human cancer | Q37500308 | ||
Hypoxia, angiogenesis and cancer therapy: to breathe or not to breathe? | Q37601177 | ||
TNF-alpha/NF-kappaB/Snail pathway in cancer cell migration and invasion | Q37678189 | ||
Hypoxic induction of Ctgf is directly mediated by Hif-1. | Q38337618 | ||
Lo, and the niche is knit: lysyl oxidase activity and maintenance of lung, aorta, and skin integrity | Q38596551 | ||
Role of Wnt/beta-catenin signaling pathway in epithelial-mesenchymal transition of human prostate cancer induced by hypoxia-inducible factor-1alpha | Q40063538 | ||
Alterations in DNA repair gene expression under hypoxia: elucidating the mechanisms of hypoxia-induced genetic instability | Q40335526 | ||
beta-catenin signaling and regulation of cyclin D1 promoter in NRK-49F cells transformed by down-regulation of the tumor suppressor lysyl oxidase | Q40411627 | ||
The relationship between bone metastasis from human breast cancer and integrin alpha(v)beta3 expression. | Q40437776 | ||
Phase I evaluation of a fully human anti-alphav integrin monoclonal antibody (CNTO 95) in patients with advanced solid tumors. | Q40453891 | ||
Connective tissue growth factor increased by hypoxia may initiate angiogenesis in collaboration with matrix metalloproteinases. | Q40731011 | ||
Cadherin expression in carcinomas: role in the formation of cell junctions and the prevention of invasiveness | Q40760011 | ||
Connective tissue growth factor as a major angiogenic agent that is induced by hypoxia in a human breast cancer cell line | Q40772926 | ||
Extracellular matrix from embryonic myocardium elicits an early morphogenetic event in cardiac endothelial differentiation | Q41454169 | ||
Cancer and infection: estimates of the attributable fraction in 1990. | Q41498906 | ||
Post-translational glycosylation and proteolytic processing of a lysyl oxidase precursor. | Q41628295 | ||
Opposing effects of hypoxia on expression of the angiogenic inhibitor thrombospondin 1 and the angiogenic inducer vascular endothelial growth factor. | Q41750906 | ||
Desmoplastic reaction influences pancreatic cancer growth behavior | Q42468547 | ||
A switch from E-cadherin to N-cadherin expression indicates epithelial to mesenchymal transition and is of strong and independent importance for the progress of prostate cancer | Q42522113 | ||
Autocrine transforming growth factor-beta signaling mediates Smad-independent motility in human cancer cells. | Q42527689 | ||
The proteolytic processing site of the precursor of lysyl oxidase. | Q42824263 | ||
Lysyl oxidase expression is an independent marker of prognosis and a predictor of lymph node metastasis in oral and oropharyngeal squamous cell carcinoma (OSCC). | Q43264716 | ||
Expression of integrin alphaVbeta3 in pancreatic carcinoma: relation to MMP-2 activation and lymph node metastasis. | Q44079888 | ||
Role of prolyl hydroxylation in oncogenically stabilized hypoxia-inducible factor-1alpha | Q44108492 | ||
Lysyl oxidase is required for vascular and diaphragmatic development in mice | Q44243394 | ||
Levels of expression of CYR61 and CTGF are prognostic for tumor progression and survival of individuals with gliomas | Q44418604 | ||
Comparative immunocytochemical localization of lysyl oxidase (LOX) and the lysyl oxidase-like (LOXL) proteins: changes in the expression of LOXL during development and growth of mouse tissues | Q45194238 | ||
Expression of lysyl oxidase is correlated with lymph node metastasis and poor prognosis in esophageal squamous cell carcinoma. | Q45969475 | ||
Loss of HIF-1alpha in endothelial cells disrupts a hypoxia-driven VEGF autocrine loop necessary for tumorigenesis. | Q46033311 | ||
E-cadherin suppression accelerates squamous cell carcinoma progression in three-dimensional, human tissue constructs. | Q51531889 | ||
Regulation of E-cadherin expression by VHL and hypoxia-inducible factor. | Q53347755 | ||
Epithelial to mesenchymal transition: expression of the regulators snail, slug, and twist in pancreatic cancer. | Q55044320 | ||
Alpha(v)beta3 and alpha(v)beta5 integrin expression in glioma periphery. | Q55474171 | ||
Vessel cooption, regression, and growth in tumors mediated by angiopoietins and VEGF. | Q55476886 | ||
Expression and differential regulation of connective tissue growth factor in pancreatic cancer cells | Q60609535 | ||
Tumor oxygenation and reoxygenation during radiation therapy: their importance in predicting tumor response | Q69491072 | ||
Morphologic and hemodynamic comparison of tumor and healing normal tissue microvasculature | Q69651963 | ||
Connective tissue growth factor gene expression in tissue sections from localized scleroderma, keloid, and other fibrotic skin disorders | Q71049546 | ||
Integrin alpha V beta 3 expression by bone-residing breast cancer metastases | Q71312522 | ||
Histone H1 is a substrate for lysyl oxidase and contains endogenous sodium borotritide-reducible residues | Q72561527 | ||
Expression of connective tissue growth factor in cartilaginous tumors | Q73025432 | ||
P433 | issue | 2 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | hypoxia | Q105688 |
P304 | page(s) | 285-293 | |
P577 | publication date | 2010-06-01 | |
P1433 | published in | Cancer and Metastasis Reviews | Q2647982 |
P1476 | title | Hypoxia, inflammation, and the tumor microenvironment in metastatic disease | |
P478 | volume | 29 |
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Q24322269 | A Cullin3-KLHL20 Ubiquitin ligase-dependent pathway targets PML to potentiate HIF-1 signaling and prostate cancer progression |
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Q36040206 | ATF4-dependent induction of heme oxygenase 1 prevents anoikis and promotes metastasis. |
Q38114319 | Acid-sensing ion channels under hypoxia |
Q35810840 | Active roles of tumor stroma in breast cancer metastasis |
Q35085751 | Akt2 regulates all Akt isoforms and promotes resistance to hypoxia through induction of miR-21 upon oxygen deprivation |
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Q64941725 | Anti-inflammation and Anti-Cancer Activity of Ethanol Extract of Antarctic Freshwater Microalga, Micractinium sp. |
Q30399006 | Antiangiogenesis strategies revisited: from starving tumors to alleviating hypoxia |
Q52646033 | Antitumor effect of a Pt-loaded nanocomposite based on graphene quantum dots combats hypoxia-induced chemoresistance of oral squamous cell carcinoma. |
Q47137400 | BMPR2 and HIF1-α overexpression in resected osteosarcoma correlates with distant metastasis and patient survival |
Q37264934 | BRG1 and BRM chromatin-remodeling complexes regulate the hypoxia response by acting as coactivators for a subset of hypoxia-inducible transcription factor target genes |
Q40202794 | BRMS1 gene expression may be associated with clinico-pathological features of breast cancer |
Q35600151 | Bioengineering embryonic stem cell microenvironments for the study of breast cancer |
Q89765517 | Biophysical Regulation of Cancer Stem/Initiating Cells: Implications for Disease Mechanisms and Translation |
Q38259683 | Bone marrow-derived stem cell therapy for metastatic brain cancers |
Q37662627 | CTGF is a therapeutic target for metastatic melanoma. |
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Q37106779 | Cbl-b promotes cell detachment via ubiquitination of focal adhesion kinase |
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Q86911827 | Characterization of clear cell renal cell carcinoma by gene expression profiling |
Q39387590 | Chemokine C-C motif receptor 5 and C-C motif ligand 5 promote cancer cell migration under hypoxia |
Q90571077 | Chemoresistance of Cancer Cells: Requirements of Tumor Microenvironment-mimicking In Vitro Models in Anti-Cancer Drug Development |
Q35575974 | Chronic inflammation and immunologic-based constraints in malignant disease |
Q92840556 | Cisplatin inhibits the growth, migration and invasion of cervical cancer cells by down-regulating IL-17E/IL-17RB |
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Q92736052 | Decoding the Biology of Exosomes in Metastasis |
Q36261594 | Decreased expression of mucin 18 is associated with unfavorable postoperative prognosis in patients with clear cell renal cell carcinoma |
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Q51079367 | Dynamic contrast-enhanced MR imaging in predicting progression of enhancing lesions persisting after standard treatment in glioblastoma patients: a prospective study. |
Q36020972 | Elevated MARCKS phosphorylation contributes to unresponsiveness of breast cancer to paclitaxel treatment |
Q47098374 | Elevation of adenylate energy charge by angiopoietin-like 4 enhances epithelial-mesenchymal transition by inducing 14-3-3γ expression |
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Q28397739 | Exosomes reflect the hypoxic status of glioma cells and mediate hypoxia-dependent activation of vascular cells during tumor development |
Q37001207 | Expression and clinical significance of glucose transporter-1 in pancreatic cancer |
Q37610995 | Expression of metastasis suppressor BRMS1 in breast cancer cells results in a marked delay in cellular adhesion to matrix. |
Q51563028 | Expression of somatostatin receptor 2A in medullary thyroid carcinoma is associated with lymph node metastasis. |
Q38783439 | Extracellular Vesicles in Cancer: Cell-to-Cell Mediators of Metastasis |
Q39389732 | Extracellular Vesicles in Renal Pathophysiology. |
Q37580365 | Extracellular translationally controlled tumor protein promotes colorectal cancer invasion and metastasis through Cdc42/JNK/ MMP9 signaling. |
Q35938289 | Flavokawain B induced cytotoxicity in two breast cancer cell lines, MCF-7 and MDA-MB231 and inhibited the metastatic potential of MDA-MB231 via the regulation of several tyrosine kinases In vitro |
Q38867010 | Fucoidan Suppresses Hypoxia-Induced Lymphangiogenesis and Lymphatic Metastasis in Mouse Hepatocarcinoma |
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Q92631456 | Global extracellular vesicle proteomic signature defines U87-MG glioma cell hypoxic status with potential implications for non-invasive diagnostics |
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Q33611004 | HIFs enhance the transcriptional activation and splicing of adrenomedullin |
Q54354561 | Heme oxygenase 1 (HO-1) challenges the angiogenic switch in prostate cancer. |
Q49205660 | Herbal compound Teng-Long-Bu-Zhong-Tang inhibits metastasis in human RKO colon carcinoma |
Q36175681 | High-mobility group box 1 activates caspase-1 and promotes hepatocellular carcinoma invasiveness and metastases |
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Q37092893 | Hyperbaric oxygen preconditioning attenuates hyperglycemia-enhanced hemorrhagic transformation by inhibiting matrix metalloproteinases in focal cerebral ischemia in rats. |
Q34820282 | Hypoxia and the extracellular matrix: drivers of tumour metastasis |
Q38935440 | Hypoxia induced E-cadherin involving regulators of Hippo pathway due to HIF-1α stabilization/nuclear translocation in bone metastasis from breast carcinoma. |
Q35762937 | Hypoxia induced HMGB1 and mitochondrial DNA interactions mediate tumor growth in hepatocellular carcinoma through Toll-like receptor 9 |
Q35987892 | Hypoxia induces IGFBP3 in esophageal squamous cancer cells through HIF-1α-mediated mRNA transcription and continuous protein synthesis |
Q47218239 | Hypoxia induces epithelial-mesenchymal transition in colorectal cancer cells through ubiquitin-specific protease 47-mediated stabilization of Snail: A potential role of Sox9. |
Q47930181 | Hypoxia mediates mitochondrial biogenesis in hepatocellular carcinoma to promote tumor growth through HMGB1 and TLR9 interaction. |
Q34177914 | Hypoxia regulates alternative splicing of HIF and non-HIF target genes. |
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