Saikosaponins induced hepatotoxicity in mice via lipid metabolism dysregulation and oxidative stress: a proteomic study

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Saikosaponins induced hepatotoxicity in mice via lipid metabolism dysregulation and oxidative stress: a proteomic study is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1084927425
P356DOI10.1186/S12906-017-1733-0
P932PMC publication ID5395759
P698PubMed publication ID28420359

P2093author name stringLili Lv
Xiaoyu Li
Rong Sun
Runping Liu
Xiaojiaoyang Li
Youyi Huang
Yongfu Luan
Junxian Lu
P2860cites workAssociations between prescribed Chinese herbal medicine and risk of hepatocellular carcinoma in patients with chronic hepatitis B: a nationwide population-based cohort studyQ37612137
Drug-induced toxicity on mitochondria and lipid metabolism: mechanistic diversity and deleterious consequences for the liverQ37818983
Genus Bupleurum: a review of its phytochemistry, pharmacology and modes of actionQ37900329
Compatibility art of traditional Chinese medicine: from the perspective of herb pairsQ38032665
A systematic review of the active saikosaponins and extracts isolated from Radix Bupleuri and their applicationsQ39036489
Incidence and clinical features of liver injury related to Kampo (Japanese herbal) medicine in 2,496 cases between 1979 and 1999: problems of the lymphocyte transformation test as a diagnostic methodQ40578707
Adjunctive traditional Chinese medicine therapy improves survival of liver cancer patientsQ41070315
"Dose-toxicity" relationship study on rat's chronic hepatoxicity of refined products of saikosaponin by alcohol elutionQ42784585
Study on hepatotoxicity on rats caused by crude extracts of total saikosaponins and correlation with oxidative damage mechanismQ42878581
Comparative research of different Bupleurum chinense composition to influence of hepatotoxicity of rats and oxidative damage mechanismQ43210790
Proteomic analysis of hepatic ischemia/reperfusion injury and ischemic preconditioning in mice revealed the protective role of ATP5betaQ44063165
Effect of sho-saiko-to(xiao-chai-hu-tang) on HBeAg clearance in children with chronic hepatitis B virus infection and with sustained liver diseaseQ44207078
Prospective study of chemoprevention of hepatocellular carcinoma with Sho-saiko-to (TJ-9).Q45101191
Fast determination of saikosaponins in Bupleurum by rapid resolution liquid chromatography with evaporative light scattering detectionQ46129406
High performance liquid chromatographic assay of saikosaponins from radix Bupleuri in ChinaQ46686284
Liver injury induced by a Japanese herbal medicine, sairei-to (TJ-114, Bupleurum and Hoelen Combination, Chai-Ling-Tang) R1.Q53558468
Expression and activity of the cytochrome P450 2E1 in patients with nonalcoholic steatosis and steatohepatitisQ80580858
A hospital clinic-based survey on traditional Chinese medicine usage among chronic hepatitis B patientsQ81186446
Effects of a high-fat diet on energy metabolism and ROS production in rat liverQ82615002
Acute hepatitis induced by Chinese hepatoprotective herb, xiao-chai-hu-tangQ82999297
Plasma and liver proteomic analysis of 3Z-3-[(1H-pyrrol-2-yl)-methylidene]-1-(1-piperidinylmethyl)-1,3-2H-indol-2-one-induced hepatotoxicity in Wistar ratsQ84397513
Risk of liver injury associated with Chinese herbal products containing radix bupleuri in 639,779 patients with hepatitis B virus infectionQ21135574
BAG5 protects against mitochondrial oxidative damage through regulating PINK1 degradationQ24324175
Sorting out the roles of PPAR alpha in energy metabolism and vascular homeostasisQ24541529
Current Status of Herbal Medicines in Chronic Liver Disease Therapy: The Biological Effects, Molecular Targets and Future ProspectsQ26775055
The anti-apoptotic effect of regucalcin is mediated through multisignaling pathwaysQ27004426
Palmitate induces insulin resistance in H4IIEC3 hepatocytes through reactive oxygen species produced by mitochondriaQ28573343
"Dose-time-toxicity" relationship study on hepatotoxicity caused by multiple dose of total Bupleurum saponin crude extracts to ratsQ33856148
ER calcium release promotes mitochondrial dysfunction and hepatic cell lipotoxicity in response to palmitate overloadQ33906433
GProX, a user-friendly platform for bioinformatics analysis and visualization of quantitative proteomics dataQ33908099
Reduced endoplasmic reticulum luminal calcium links saturated fatty acid-mediated endoplasmic reticulum stress and cell death in liver cellsQ33974369
A multicenter randomized controlled clinical trial of Shosaiko-to in chronic active hepatitis.Q34675881
Liver injuries induced by herbal medicine, syo-saiko-to (xiao-chai-hu-tang).Q34721069
Minireview: lipid metabolism, metabolic diseases, and peroxisome proliferator-activated receptorsQ35127251
Inhibition of fatty acid oxidation enhances oxidative protein folding and protects hepatocytes from endoplasmic reticulum stressQ35790896
Endoplasmic reticulum stress in liver diseaseQ36031838
Structural and functional hepatocyte polarity and liver diseaseQ36090717
Utilization and prescription patterns of traditional Chinese medicine for patients with hepatitis C in Taiwan: a population-based studyQ36171377
Taurocholate Induces Cyclooxygenase-2 Expression via the Sphingosine 1-phosphate Receptor 2 in a Human Cholangiocarcinoma Cell LineQ36407288
Functionally defective high-density lipoprotein: a new therapeutic target at the crossroads of dyslipidemia, inflammation, and atherosclerosisQ36591939
Practical points in urinary proteomicsQ36933641
Advances in urinary proteome analysis and biomarker discovery in pediatric renal diseaseQ37551660
P433issue1
P921main subjecthepatotoxicityQ1349821
P304page(s)219
P577publication date2017-04-19
P1433published inBMC Complementary and Alternative MedicineQ15755965
P1476titleSaikosaponins induced hepatotoxicity in mice via lipid metabolism dysregulation and oxidative stress: a proteomic study
P478volume17

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cites work (P2860)
Q42177619Comparative Evaluation between Sulfasalazine Alone and in Combination with Herbal Medicine on DSS-Induced Ulcerative Colitis Mice
Q60916025Differential proteomics for studying action mechanisms of traditional Chinese medicines
Q58742281Molecular Mechanisms Involved in Oxidative Stress-Associated Liver Injury Induced by Chinese Herbal Medicine: An Experimental Evidence-Based Literature Review and Network Pharmacology Study
Q93241696Saikosaponin d causes apoptotic death of cultured neocortical neurons by increasing membrane permeability and elevating intracellular Ca2+ concentration
Q90330418Sample Multiplexing Strategies in Quantitative Proteomics

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