No strict alignment is required between a transcriptional activator binding site and the "TATA box" of a yeast gene

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No strict alignment is required between a transcriptional activator binding site and the "TATA box" of a yeast gene is …
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scholarly articleQ13442814

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P819ADS bibcode1988PNAS...85.4262R
P356DOI10.1073/PNAS.85.12.4262
P932PMC publication ID280407
P698PubMed publication ID3132708
P5875ResearchGate publication ID20022996

P2093author name stringJ Ma
M Ptashne
D M Ruden
P2860cites workProtein-DNA recognitionQ22065421
Transformation of intact yeast cells treated with alkali cationsQ24672708
Functional dissection of a eukaryotic transcriptional activator protein, GCN4 of yeastQ27933378
Separation of DNA binding from the transcription-activating function of a eukaryotic regulatory proteinQ27936825
Amino terminus of the yeast GAL4 gene product is sufficient for nuclear localizationQ27937444
Specific DNA binding of GAL4, a positive regulatory protein of yeastQ27939693
Extensive homology among the largest subunits of eukaryotic and prokaryotic RNA polymerasesQ29617053
A new class of yeast transcriptional activatorsQ29620215
Deletion analysis of GAL4 defines two transcriptional activating segmentsQ29620547
A GAL family of upstream activating sequences in yeast: roles in both induction and repression of transcriptionQ33879592
lac repressor forms loops with linear DNA carrying two suitably spaced lac operatorsQ33930312
Yeast mRNA initiation sites are determined primarily by specific sequences, not by the distance from the TATA elementQ33932034
Mutants of GAL4 protein altered in an activation functionQ34166478
A eukaryotic transcriptional activator bearing the DNA specificity of a prokaryotic repressorQ34194676
Isolation and preliminary characterization of the GAL4 gene, a positive regulator of transcription in yeastQ36320254
Isolation of the yeast regulatory gene GAL4 and analysis of its dosage effects on the galactose/melibiose regulonQ36321195
Use of lacZ fusions to delimit regulatory elements of the inducible divergent GAL1-GAL10 promoter in Saccharomyces cerevisiaeQ36948243
Saccharomyces cerevisiae GAL1-GAL10 divergent promoter region: location and function of the upstream activating sequence UASG.Q36950051
Cooperative DNA binding of the yeast transcriptional activator GAL4.Q37482164
The relationship between the "TATA" sequence and transcription initiation sites at the HIS4 gene of Saccharomyces cerevisiaeQ37540236
Each of three "TATA elements" specifies a subset of the transcription initiation sites at the CYC-1 promoter of Saccharomyces cerevisiaeQ37540263
An operator at -280 base pairs that is required for repression of araBAD operon promoter: addition of DNA helical turns between the operator and promoter cyclically hinders repressionQ37562777
Gene regulation by proteins acting nearby and at a distanceQ39504312
DNA supercoiling changes the spacing requirement of two lac operators for DNA loop formation with lac repressor.Q41091317
Regulation of genes controlling synthesis of the galactose pathway enzymes in yeast.Q41821687
Genetic evidence that zinc is an essential co-factor in the DNA binding domain of GAL4 proteinQ43410990
Cooperative binding of lambda repressors to sites separated by integral turns of the DNA helixQ43484354
DNA loops induced by cooperative binding of lambda repressorQ44068391
Requirement of stereospecific alignments for initiation from the simian virus 40 early promoterQ45837537
Functional redundancy and structural polymorphism in the large subunit of RNA polymerase II.Q48338515
Transcription initiation of the Saccharomyces cerevisiae iso-1-cytochrome c gene. Multiple, independent T-A-T-A sequencesQ48368650
A Drosophila RNA polymerase II transcription factor binds to the regulatory site of an hsp 70 geneQ48390690
A Drosophila RNA polymerase II transcription factor contains a promoter-region-specific DNA-binding activityQ48392773
Transcription of Escherichia coli ara in vitro. The cyclic AMP receptor protein requirement for PBAD induction that depends on the presence and orientation of the araO2 site.Q54146636
Interaction of a gene-specific transcription factor with the adenovirus major late promoter upstream of the TATA box region.Q54739833
Photofootprinting in vivo detects transcription-dependent changes in yeast TATA boxesQ59073930
Formation of stable preinitiation complexes between eukaryotic class B transcription factors and promoter sequencesQ59074628
An octamer oligonucleotide upstream of a TATA motif is sufficient for lymphoid-specific promoter activityQ59094880
Transcription in yeast activated by a putative amphipathic α helix linked to a DNA binding unitQ59097327
The adenovirus major late transcription factor activates the rat gamma-fibrinogen promoterQ64379675
Normal and mutant human β-globin pre-mRNAs are faithfully and efficiently spliced in vitroQ70196254
P433issue12
P407language of work or nameEnglishQ1860
P304page(s)4262-4266
P577publication date1988-06-01
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleNo strict alignment is required between a transcriptional activator binding site and the "TATA box" of a yeast gene
P478volume85

Reverse relations

cites work (P2860)
Q68110839Activating regions of yeast transcription factors must have both acidic and hydrophobic amino acids
Q47846286Actively seeking activating sequences
Q37680899Allosteric mechanism of enhancer action?
Q42821723An inverted TATA box directs downstream transcription of the bone sialoprotein gene
Q28732365Distance and helical phase dependence of synergistic transcription activation in cis-regulatory module
Q45085958Distinct upstream activation regions for glucose-repressed and derepressed expression of the yeast citrate synthase gene CIT1.
Q40646895Functional domains of a negative regulatory protein, GAL80, of Saccharomyces cerevisiae
Q34047887GAL4 is regulated by a glucose-responsive functional domain.
Q36710932GAL4 protein: purification, association with GAL80 protein, and conserved domain structure
Q34012305HMG proteins and DNA flexibility in transcription activation
Q44004756Host versus in vitro signals and intrastrain allelic differences in the expression of a Candida albicans virulence gene
Q36755102Identification of Schizosaccharomyces pombe transcription factor PGA4, which binds cooperatively to Saccharomyces cerevisiae GAL4-binding sites
Q36695042In vivo stimulation of a chimeric promoter by binding sites for nuclear factor I.
Q27931896Isolation and analysis of the yeast TEA1 gene, which encodes a zinc cluster Ty enhancer-binding protein
Q40504337Lack of a requirement for strict rotational alignment among transcription factor binding sites in yeast
Q35864691Liver cell specific gene transcription in vitro: the promoter elements HP1 and TATA box are necessary and sufficient to generate a liver-specific promoter
Q33850755Mutations in RNA polymerase II enhance or suppress mutations in GAL4.
Q36731788Opposing regulatory functions of positive and negative elements in UASG control transcription of the yeast GAL genes.
Q37401017Phased cis-acting promoter elements interact at short distances to direct avian skeletal alpha-actin gene transcription
Q36695907Promoter elements determining weak expression of the GAL4 regulatory gene of Saccharomyces cerevisiae
Q47141163SAGA mediates transcription from the TATA-like element independently of Taf1p/TFIID but dependent on core promoter structures in Saccharomyces cerevisiae.
Q40453410Stereospecific relationships between elements in an SV40/adenovirus-2 heterologous promoter
Q36717450Synergy between the NF-E1 erythroid-specific transcription factor and the CACCC factor in the erythroid-specific promoter of the human porphobilinogen deaminase gene
Q35931254Synthetic Transcription Amplifier System for Orthogonal Control of Gene Expression in Saccharomyces cerevisiae
Q37608414The chemistry of regulation of genes and other things
Q37593329The initiator directs the assembly of a transcription factor IID-dependent transcription complex
Q54578628The role of multiple binding sites in the activation of zein gene expression by Opaque-2.
Q33919791Transcription factor Oct-2A contains functionally redundant activating domains and works selectively from a promoter but not from a remote enhancer position in non-lymphoid (HeLa) cells
Q35801189Transcription factor binding and spacing constraints in the human β-actin proximal promoter
Q35955508Two closely spaced promoters are equally activated by a remote enhancer: evidence against a scanning model for enhancer action

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