A functional kinase homology domain is essential for the activity of photoreceptor guanylate cyclase 1

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A functional kinase homology domain is essential for the activity of photoreceptor guanylate cyclase 1 is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M109.061713
P932PMC publication ID2804348
P698PubMed publication ID19901021

P50authorKrzysztof PalczewskiQ6440188
Grzegorz P. BeretaQ85225438
Philip D KiserQ87943115
Benlian WangQ125251921
P2093author name stringWolfgang Baehr
Geeng-Fu Jang
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The function of guanylate cyclase 1 and guanylate cyclase 2 in rod and cone photoreceptorsQ28585678
Role of guanylate cyclase-activating proteins (GCAPs) in setting the flash sensitivity of rod photoreceptorsQ28593705
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Ca(2+)-binding proteins in the retina: structure, function, and the etiology of human visual diseasesQ33866720
Phosphorylation of the kinase homology domain is essential for activation of the A-type natriuretic peptide receptorQ33995684
GCAP1 rescues rod photoreceptor response in GCAP1/GCAP2 knockout miceQ34078737
Lecithin-retinol acyltransferase is essential for accumulation of all-trans-retinyl esters in the eye and in the liver.Q34313782
Kinetic and catalytic mechanisms of protein kinasesQ34465987
G protein-coupled receptor rhodopsinQ35017269
Site-directed and natural mutations in studying functional domains in guanylyl cyclase activating proteins (GCAPs).Q35070077
Target recognition of guanylate cyclase by guanylate cyclase-activating proteinsQ35070094
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Interaction of retinal guanylate cyclase with the alpha subunit of transducin: potential role in transducin localizationQ35851844
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A constitutively "phosphorylated" guanylyl cyclase-linked atrial natriuretic peptide receptor mutant is resistant to desensitizationQ36879609
Adenine nucleotides are required for activation of rat atrial natriuretic peptide receptor/guanylyl cyclase expressed in a baculovirus systemQ38336233
Adenine nucleotides decrease the apparent Km of endogenous natriuretic peptide receptors for GTP.Q40082312
GTP hydrolysis in intact rod outer segments and the transmitter cycle in visual excitationQ40240436
Atrial natriuretic peptide-dependent photolabeling of a regulatory ATP-binding site on the natriuretic peptide receptor-A.Q40355831
Conservation of the kinaselike regulatory domain is essential for activation of the natriuretic peptide receptor guanylyl cyclasesQ40655018
Crystal structure of hormone-bound atrial natriuretic peptide receptor extracellular domain: rotation mechanism for transmembrane signal transductionQ41166663
Turned on by Ca2+! The physiology and pathology of Ca(2+)-binding proteins in the retinaQ41265445
Phosphorylation of the polymeric immunoglobulin receptor required for its efficient transcytosisQ41734406
Free Magnesium Concentration in Salamander Photoreceptor Outer SegmentsQ42450393
cAMP-dependent protein kinase: crystallographic insights into substrate recognition and phosphotransferQ42844060
Interactions within the coiled-coil domain of RetGC-1 guanylyl cyclase are optimized for regulation rather than for high affinityQ43578129
Identification of proximate regions in a complex of retinal guanylyl cyclase 1 and guanylyl cyclase-activating protein-1 by a novel mass spectrometry-based methodQ43626735
Spontaneous activity of opsin apoprotein is a cause of Leber congenital amaurosisQ44601261
Rational scanning mutagenesis of a protein kinase identifies functional regions involved in catalysis and substrate interactionsQ46112210
Proper glycosylation and phosphorylation of the type A natriuretic peptide receptor are required for hormone-stimulated guanylyl cyclase activity.Q46123511
Structure of the atrial natriuretic peptide receptor extracellular domain in the unbound and hormone-bound states by single-particle electron microscopyQ46136567
A sensitive method for determining the phosphorylation status of natriuretic peptide receptors: cGK-Ialpha does not regulate NPR-A.Q46906529
Molecular cloning and characterization of retinal photoreceptor guanylyl cyclase-activating proteinQ48080751
Disruption of a retinal guanylyl cyclase gene leads to cone-specific dystrophy and paradoxical rod behavior.Q52535765
ATP signaling site in the ARM domain of atrial natriuretic factor receptor guanylate cyclase.Q53579099
Reproducible isolation of distinct, overlapping segments of the phosphoproteomeQ57205837
The protein kinase domain of the ANP receptor is required for signalingQ69374143
Nucleotide inhibitors and activators of retinal guanylyl cyclaseQ71614964
The photoreceptor guanylate cyclase is an autophosphorylating protein kinaseQ71742733
P4510describes a project that usesImageQuantQ112270642
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectphotoreceptor proteinQ7187894
P304page(s)1899-1908
P577publication date2009-11-09
P1433published inJournal of Biological ChemistryQ867727
P1476titleA functional kinase homology domain is essential for the activity of photoreceptor guanylate cyclase 1
P478volume285

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cites work (P2860)
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Q34062548High density and ligand affinity confer ultrasensitive signal detection by a guanylyl cyclase chemoreceptor.
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Q57492090Photoreceptor Guanylate Cyclase () Mutations Cause Retinal Dystrophies by Severe Malfunction of Ca-Dependent Cyclic GMP Synthesis
Q35502282Posttranslational modifications of the photoreceptor-specific ABC transporter ABCA4
Q36867743Regulation and therapeutic targeting of peptide-activated receptor guanylyl cyclases
Q38256004Retinal phototransduction
Q35489283Targeting of mouse guanylate cyclase 1 (Gucy2e) to Xenopus laevis rod outer segments

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