Ca2+ sparks act as potent regulators of excitation-contraction coupling in airway smooth muscle

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Ca2+ sparks act as potent regulators of excitation-contraction coupling in airway smooth muscle is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M109.067546
P932PMC publication ID2804376
P698PubMed publication ID19920135

P50authorLawrence M LifshitzQ88861999
P2093author name stringKevin E Fogarty
Ronghua Zhuge
Rongfeng Bao
P2860cites workA new generation of Ca2+ indicators with greatly improved fluorescence propertiesQ27860793
Local Ca(2+) transients and distribution of BK channels and ryanodine receptors in smooth muscle cells of guinea-pig vas deferens and urinary bladderQ28343998
Overactive bladder and incontinence in the absence of the BK large conductance Ca2+-activated K+ channelQ28507619
Diminished surface clustering and increased perinuclear accumulation of large conductance Ca2+-activated K+ channel in mouse myometrium with pregnancyQ28585308
Ionic mechanisms and Ca(2+) regulation in airway smooth muscle contraction: do the data contradict dogma?Q30692245
Voltage dependence of the coupling of Ca(2+) sparks to BK(Ca) channels in urinary bladder smooth muscleQ31919329
Relationship between force and Ca2+ concentration in smooth muscle as revealed by measurements on single cellsQ33579650
Calcium sparksQ34014173
Chloride in smooth muscleQ34166922
Action potential refractory period in ureter smooth muscle is set by Ca sparks and BK channelsQ34437712
Ca2+ currents in cerebral artery smooth muscle cells of rat at physiological Ca2+ concentrationsQ36411749
Dynamics of signaling between Ca(2+) sparks and Ca(2+)- activated K(+) channels studied with a novel image-based method for direct intracellular measurement of ryanodine receptor Ca(2+) currentQ36440883
Spontaneous transient outward currents arise from microdomains where BK channels are exposed to a mean Ca(2+) concentration on the order of 10 microM during a Ca(2+) sparkQ36558172
A close association of RyRs with highly dense clusters of Ca2+-activated Cl- channels underlies the activation of STICs by Ca2+ sparks in mouse airway smooth muscleQ36741199
Diabetes downregulates large-conductance Ca2+-activated potassium beta 1 channel subunit in retinal arteriolar smooth muscleQ37000197
Ca2+ sparks activate K+ and Cl- channels, resulting in spontaneous transient currents in guinea-pig tracheal myocytesQ39480338
Ca(2+) spark sites in smooth muscle cells are numerous and differ in number of ryanodine receptors, large-conductance K(+) channels, and coupling ratio between themQ39691990
Potentiation of large conductance KCa channels by niflumic, flufenamic, and mefenamic acidsQ43005711
Ca2+-activated Cl- channels in corpus cavernosum smooth muscle: a novel mechanism for control of penile erectionQ44187559
Functional coupling between the Na+/Ca2+ exchanger and nonselective cation channels during histamine stimulation in guinea pig tracheal smooth muscleQ46357360
Vasoregulation by the beta1 subunit of the calcium-activated potassium channelQ46410172
Downregulation of the BK Channel β1 Subunit in Genetic HypertensionQ47449758
Mice with disrupted BK channel beta1 subunit gene feature abnormal Ca(2+) spark/STOC coupling and elevated blood pressure.Q52541601
Photobleaching of fura-2 and its effect on determination of calcium concentrations.Q52587567
Reduced rather than enhanced cholinergic airway constriction in mice with ablation of the large conductance Ca2+-activated K+ channelQ57987892
Properties of spontaneous inward currents recorded in smooth muscle cells isolated from the rabbit portal veinQ67559305
Spontaneous transient inward currents and rhythmicity in canine and guinea-pig tracheal smooth muscle cellsQ71658398
Relaxation of arterial smooth muscle by calcium sparksQ71768395
Pacemaker potentials in lymphatic smooth muscle of the guinea-pig mesenteryQ72274905
Ion currents in smooth muscle cells from human small bronchioles: presence of an inward rectifier K+ current and three types of large conductance K+ channelQ73032049
Defective excitation-contraction coupling in experimental cardiac hypertrophy and heart failureQ73257762
Modulation of maxi-K+ channels by voltage-dependent Ca2+ channels and methacholine in single airway myocytesQ73322656
Release of Ca2+ from the sarcoplasmic reticulum increases mitochondrial [Ca2+] in rat pulmonary artery smooth muscle cellsQ74583857
Uncontrolled calcium sparks act as a dystrophic signal for mammalian skeletal muscleQ81657096
P433issue3
P407language of work or nameEnglishQ1860
P1104number of pages8
P304page(s)2203-2210
P577publication date2009-11-17
P1433published inJournal of Biological ChemistryQ867727
P1476titleCa2+ sparks act as potent regulators of excitation-contraction coupling in airway smooth muscle
P478volume285

Reverse relations

cites work (P2860)
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