Higher susceptibility to halothane modulation in open- than in closed-channel alpha4beta2 nAChR revealed by molecular dynamics simulations

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Higher susceptibility to halothane modulation in open- than in closed-channel alpha4beta2 nAChR revealed by molecular dynamics simulations is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1021/JP908944E
P8608Fatcat IDrelease_7scdegmlljaybh5bzepcnrbwry
P932PMC publication ID2805416
P698PubMed publication ID20014754
P5875ResearchGate publication ID40692139

P50authorYan XuQ44456770
P2093author name stringPei Tang
Esmael J Haddadian
Lu Tian Liu
Dan Willenbring
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Alpha 4 beta 2 neuronal nicotinic acetylcholine receptors in the central nervous system are inhibited by isoflurane and propofol, but alpha 7-type nicotinic acetylcholine receptors are unaffectedQ48748312
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Effects of alcohols and volatile anesthetics on the activation of nicotinic acetylcholine receptor channels.Q51633840
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Dynamics of heteropentameric nicotinic acetylcholine receptor: implications of the gating mechanismQ80424010
P4510describes a project that usesmolecular dynamics simulationQ901663
P433issue1
P407language of work or nameEnglishQ1860
P921main subjecthalothaneQ32921
P304page(s)626-632
P577publication date2010-01-01
P1433published inJournal of Physical Chemistry BQ668669
P1476titleHigher susceptibility to halothane modulation in open- than in closed-channel alpha4beta2 nAChR revealed by molecular dynamics simulations
P478volume114

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cites work (P2860)
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Q33923082Unresponsive correlated motion in alpha7 nAChR to halothane binding explains its functional insensitivity to volatile anesthetics

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