review article | Q7318358 |
scholarly article | Q13442814 |
P356 | DOI | 10.1016/S0889-8553(05)70041-8 |
P698 | PubMed publication ID | 10198776 |
P2093 | author name string | R T Stravitz | |
W M Pandak | |||
Z R Vlahcevic | |||
P2860 | cites work | Activation of the nuclear receptor LXR by oxysterols defines a new hormone response pathway | Q24316367 |
Transfected human liver cytochrome P-450 hydroxylates vitamin D analogs at different side-chain positions | Q24561465 | ||
Frameshift and splice-junction mutations in the sterol 27-hydroxylase gene cause cerebrotendinous xanthomatosis in Jews or Moroccan origin | Q24564653 | ||
The rat hepatic leukemia factor (HLF) gene encodes two transcriptional activators with distinct circadian rhythms, tissue distributions and target preferences | Q24598584 | ||
Cloning of the human cholesterol 7 alpha-hydroxylase gene (CYP7) and localization to chromosome 8q11-q12 | Q28183761 | ||
Regulation of bile acid synthesis | Q28260543 | ||
Circadian transcription of the cholesterol 7 alpha hydroxylase gene may involve the liver-enriched bZIP protein DBP | Q28264406 | ||
Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXR alpha | Q28273937 | ||
Molecular cloning of cDNA for vitamin D3 25-hydroxylase from rat liver mitochondria | Q28279965 | ||
Molecular cloning and expression of rabbit sterol 12alpha-hydroxylase | Q28298355 | ||
Delta 4-3-oxosteroid 5 beta-reductase deficiency described in identical twins with neonatal hepatitis. A new inborn error in bile acid synthesis | Q28361181 | ||
3 alpha-hydroxysteroid dehydrogenase activity of the Y' bile acid binders in rat liver cytosol. Identification, kinetics, and physiologic significance | Q28361617 | ||
Familial giant cell hepatitis associated with synthesis of 3 beta, 7 alpha-dihydroxy-and 3 beta,7 alpha, 12 alpha-trihydroxy-5-cholenoic acids | Q28361624 | ||
Bile Acid Synthesis in the Isolated, Perfused Rabbit Liver | Q28364763 | ||
Suppression of sterol 27-hydroxylase mRNA and transcriptional activity by bile acids in cultured rat hepatocytes | Q28368343 | ||
Atherosclerosis and sterol 27-hydroxylase: evidence for a role of this enzyme in elimination of cholesterol from human macrophages | Q28369414 | ||
A cDNA encoding a rat mitochondrial cytochrome P450 catalyzing both the 26-hydroxylation of cholesterol and 25-hydroxylation of vitamin D3: gonadotropic regulation of the cognate mRNA in ovaries | Q28567277 | ||
Regulation of the mevalonate pathway | Q29547763 | ||
Structural Aspects of Bile Acids Involved in the Regulation of Cholesterol 7alpha-Hydroxylase and Sterol 27-Hydroxylase | Q63916805 | ||
Effect of lymphatic drainage on 7alpha-hydroxylation of cholesterol in rat liver | Q67435250 | ||
7 alpha-hydroxylation of 27-hydroxycholesterol in human liver microsomes | Q67550110 | ||
7α-Hydroxylation of 26-hydroxycholesterol, 3β-hydroxy-5-cholestenoic acid and 3β-hydroxy-5-cholenoic acid by cytochromeP-450 in pig liver microsomes | Q67727197 | ||
Normal plasma cholesterol in an 88-year-old man who eats 25 eggs a day. Mechanisms of adaptation | Q68061644 | ||
Effect of thyroid hormone on hepatic cholesterol 7 alpha hydroxylase, LDL receptor, HMG-CoA reductase, farnesyl pyrophosphate synthetase and apolipoprotein A-I mRNA levels in hypophysectomized rats | Q68366770 | ||
Potential bile acid precursors in plasma--possible indicators of biosynthetic pathways to cholic and chenodeoxycholic acids in man | Q68562278 | ||
Control of circadian activity of cholesterol-7 alpha-hydroxylase by glucocorticosteroids | Q69669056 | ||
Effect of bile acid feeding on hepatic steroid 12 alpha-hydroxylase activity in hamsters | Q70459867 | ||
Hepatic cholesterol 7 alpha-hydroxylase activity and serum 7 alpha-hydroxy-cholesterol level during liver regeneration after partial hepatectomy in rats | Q70840962 | ||
7 alpha-Hydroxylation of 25-hydroxycholesterol and 27-hydroxycholesterol in human fibroblasts | Q72327248 | ||
Thyroid hormone rapidly increases cholesterol 7 alpha-hydroxylase mRNA levels in hypophysectomized rats | Q72697049 | ||
Effects of bile acids and steroid/thyroid hormones on the expression of cholesterol 7 alpha-hydroxylase mRNA and the CYP7 gene in HepG2 cells | Q72748098 | ||
Biliary excretion of cholic acid and cholesterol in hyper-, hypo-, and euthyroid rats | Q73190586 | ||
Increased bile acid pool inhibits cholesterol 7 alpha-hydroxylase in cholesterol-fed rabbits | Q73933606 | ||
Biliary excretion of bile acids and cholesterol in bile fistula rats; bile acids and steroids | Q74428268 | ||
Effects of thyroidectomy and thyroxine treatment on the activity of 12alpha-hydroxylase and of some components of microsomal electron transfer chains in rat liver | Q77913530 | ||
Excretion of 3beta-hydroxy-5-cholenoic and 3a-hydroxy-5a-cholanoic acids in urine of infants with biliary atresia | Q77916740 | ||
Cloning and 5'-flanking sequence of a rat cholesterol 7 alpha-hydroxylase gene | Q33192110 | ||
Effect of Biliary Drainage on Individual Reactions in the Conversion of Cholesterol to Taurocholic Acid. Bile Acids and Steroids 180 | Q34054626 | ||
Dietary cholesterol and downregulation of cholesterol 7 alpha-hydroxylase and cholesterol absorption in African green monkeys | Q34150907 | ||
7 alpha hydroxylation of 25-hydroxycholesterol in liver microsomes. Evidence that the enzyme involved is different from cholesterol 7 alpha-hydroxylase | Q34323275 | ||
Bile acid synthesis from cholesterol: regulatory and auxiliary pathways | Q34328308 | ||
Identification and characterization of a mouse oxysterol 7alpha-hydroxylase cDNA. | Q34439033 | ||
Effect of Oral Chenodeoxycholic Acid on Bile Acid Kinetics and Biliary Lipid Composition in Women with Cholelithiasis | Q34513427 | ||
Function and regulation of hydroxylases involved in the bile acid biosynthesis pathways | Q35600517 | ||
Disruption of cholesterol 7alpha-hydroxylase gene in mice. II. Bile acid deficiency is overcome by induction of oxysterol 7alpha-hydroxylase. | Q35671417 | ||
Adenovirus-mediated transfer of a gene encoding cholesterol 7 alpha-hydroxylase into hamsters increases hepatic enzyme activity and reduces plasma total and low density lipoprotein cholesterol | Q35752007 | ||
Bile acid biosynthesis | Q36136767 | ||
Molecular cloning of cDNA for cholesterol 7 alpha-hydroxylase from rat liver microsomes. Nucleotide sequence and expression | Q36243934 | ||
Cholesterol and bile acids regulate cholesterol 7 alpha-hydroxylase expression at the transcriptional level in culture and in transgenic mice. | Q36651232 | ||
Structure of the mouse cholesterol 7 alpha-hydroxylase gene | Q36740472 | ||
Genomic cloning, sequencing, and analysis of the hamster cholesterol 7 alpha-hydroxylase gene (CYP7). | Q36742002 | ||
Cholic acid biosynthesis: the enzymatic defect in cerebrotendinous xanthomatosis | Q37034717 | ||
Unexpected inhibition of cholesterol 7 alpha-hydroxylase by cholesterol in New Zealand white and Watanabe heritable hyperlipidemic rabbits. | Q40342532 | ||
The P450 superfamily: update on new sequences, gene mapping, accession numbers, early trivial names of enzymes, and nomenclature | Q40484461 | ||
Intracellular cholesterol transport and compartmentation | Q40554276 | ||
Heterogeneous expression of cholesterol 7 alpha-hydroxylase and sterol 27-hydroxylase genes in the rat liver lobulus | Q41010263 | ||
The opposing effects of retinoic acid and phorbol esters converge to a common response element in the promoter of the rat cholesterol 7 alpha-hydroxylase gene (CYP7A). | Q41175415 | ||
Bile acid synthesis in humans: regulation of hepatic microsomal cholesterol 7 alpha-hydroxylase activity | Q41280585 | ||
Transcriptional regulation of the human cholesterol 7.alpha.-hydroxylase gene | Q41635456 | ||
Cyclosporin A blocks bile acid synthesis in cultured hepatocytes by specific inhibition of chenodeoxycholic acid synthesis | Q42023326 | ||
Differential feedback regulation of cholesterol 7 alpha-hydroxylase mRNA and transcriptional activity by rat bile acids in primary monolayer cultures of rat hepatocytes | Q42161320 | ||
Regulation of cholesterol and bile acid homoeostasis in bile-obstructed rats | Q42286090 | ||
Transcriptional regulation of the gene encoding cholesterol 7 alpha-hydroxylase in the rat. | Q42288372 | ||
24-, 25- and 27-hydroxylation of cholesterol by a purified preparation of 27-hydroxylase from pig liver | Q42289399 | ||
Formation of 7 alpha- and 7 beta-hydroxylated bile acid precursors from 27-hydroxycholesterol in human liver microsomes and mitochondria | Q42289409 | ||
A novel nonhepatic hydroxycholesterol 7 alpha-hydroxylase that is markedly stimulated by interleukin-1 beta. Characterization in the immature rat ovary | Q42481640 | ||
Characterization of hepatic-specific regulatory elements in the promoter region of the human cholesterol 7alpha-hydroxylase gene | Q42528946 | ||
Localization of sterol 27-hydroxylase immuno-reactivity in human atherosclerotic plaques | Q42550894 | ||
The formation of cholest-5-ene-3 ,26-diol as an intermediate in the conversion of cholesterol into bile acids by liver mitochondria | Q42919405 | ||
Down-regulation of the rat hepatic sterol 27-hydroxylase gene by bile acids in transfected primary hepatocytes: possible role of hepatic nuclear factor 1alpha | Q44865122 | ||
Regulation of bile acid synthesis. II. Effect of bile acid feeding on enzymes regulating hepatic cholesterol and bile acid synthesis in the rat | Q45078863 | ||
Failure of intravenous infusion of taurocholate to down-regulate cholesterol 7 alpha-hydroxylase in rats with biliary fistulas. | Q45084966 | ||
Regulation of sterol 27-hydroxylase and an alternative pathway of bile acid biosynthesis in primary cultures of rat hepatocytes | Q45096819 | ||
Quantitative estimations of the contribution of different bile acid pathways to total bile acid synthesis in the rat. | Q45108263 | ||
Overexpression of the HDL receptor SR-BI alters plasma HDL and bile cholesterol levels | Q45881945 | ||
Structure and nucleotide sequences of the human cholesterol 7 alpha-hydroxylase gene (CYP7). | Q48084175 | ||
Structure of the rat gene encoding cholesterol 7 alpha-hydroxylase | Q48256658 | ||
Hepatic cholesterol metabolism in patients with cholesterol gallstones: enhanced intracellular transport of cholesterol | Q50165823 | ||
Disruption of cholesterol 7alpha-hydroxylase gene in mice. I. Postnatal lethality reversed by bile acid and vitamin supplementation. | Q52519814 | ||
Different effects on the expression of CYP7 and CYP27 in rabbit liver by cholic acid and cholestyramine. | Q53371746 | ||
On the regulation of bile acid formation in the rat liver. | Q53759940 | ||
Elimination of cholesterol in macrophages and endothelial cells by the sterol 27-hydroxylase mechanism. Comparison with high density lipoprotein-mediated reverse cholesterol transport | Q59307006 | ||
P433 | issue | 1 | |
P304 | page(s) | 1-25, v | |
P577 | publication date | 1999-03-01 | |
P1433 | published in | Gastroenterology Clinics of North America | Q15756082 |
P1476 | title | Regulation of bile acid biosynthesis | |
P478 | volume | 28 |
Q40644245 | A serum metabolomic analysis for diagnosis and biomarker discovery of primary biliary cirrhosis and autoimmune hepatitis |
Q35760231 | Adaptive regulation of the ileal apical sodium dependent bile acid transporter (ASBT) in patients with obstructive cholestasis |
Q51750906 | Ameliorative effect of Pracparatum mungo extract on high cholesterol diets in hamsters. |
Q40773905 | Antagonism of the actions of peroxisome proliferator-activated receptor-alpha by bile acids |
Q44300002 | Appearance of atypical 3 alpha,6 beta,7 beta,12 alpha-tetrahydroxy-5 beta-cholan-24-oic acid in spgp knockout mice |
Q30571181 | Application of faecal metabonomics on an experimental model of tubulointerstitial fibrosis by ultra performance liquid chromatography/high-sensitivity mass spectrometry with MS(E) data collection technique |
Q39156569 | Bile Acid Uptake Transporters as Targets for Therapy. |
Q37365040 | Bile Acid sulfation: a pathway of bile acid elimination and detoxification |
Q73023452 | Bile acids go nuclear! |
Q46410501 | CYP7A1 promoter polymorphism -203A>C affects bile salt synthesis rate in patients after ileal resection |
Q36765756 | Characterization of the acyl-adenylate linked metabolite of mefenamic Acid |
Q55052281 | Chronic diarrhea caused by idiopathic bile acid malabsorption: an explanation at last. |
Q44229547 | Chronic renal failure-induced changes in serum and urine bile acid profiles. |
Q57149194 | Combination of intrauterine growth restriction and a high-fat diet impairs cholesterol elimination in rats |
Q44683463 | Deoxycholic acid activates the c-Jun N-terminal kinase pathway via FAS receptor activation in primary hepatocytes. Role of acidic sphingomyelinase-mediated ceramide generation in FAS receptor activation |
Q46645436 | Dietary fatty acids regulate cholesterol induction of liver CYP7alpha1 expression and bile acid production |
Q28217573 | Differences in the regulation of the classical and the alternative pathway for bile acid synthesis in human liver. No coordinate regulation of CYP7A1 and CYP27A1 |
Q43559873 | Down-regulation of cholesterol 7alpha-hydroxylase (CYP7A1) gene expression by bile acids in primary rat hepatocytes is mediated by the c-Jun N-terminal kinase pathway |
Q46120408 | Effect of chronic renal failure on the hepatic, intestinal, and renal expression of bile acid transporters |
Q43737827 | Effects of CYP7A1 overexpression on cholesterol and bile acid homeostasis |
Q47103055 | FXR controls CHOP expression in steatohepatitis |
Q28204827 | Farnesoid X Receptor Regulates Bile Acid-Amino Acid Conjugation |
Q35044846 | Genetic background of cholesterol gallstone disease |
Q44626804 | Hepatic overexpression of murine Abcb11 increases hepatobiliary lipid secretion and reduces hepatic steatosis |
Q44635530 | Hepatocyte Nuclear Factor 4α Is a Central Regulator of Bile Acid Conjugation |
Q34793071 | Human cholesterol 7alpha-hydroxylase (CYP7A1) deficiency has a hypercholesterolemic phenotype |
Q50865980 | Hypolipidaemic effect and mechanism of paprika seed oil on Sprague-Dawley rats. |
Q40547550 | Identification of DRIP205 as a coactivator for the Farnesoid X receptor. |
Q43640406 | In vivo and in vitro regulation of sterol 27-hydroxylase in the liver during the acute phase response. potential role of hepatocyte nuclear factor-1. |
Q45045440 | In vivo regulation of murine CYP7A1 by HNF-6: a novel mechanism for diminished CYP7A1 expression in biliary obstruction |
Q35595954 | Inappropriate ileal conservation of bile acids in cholestatic liver disease: homeostasis gone awry |
Q44279101 | Increases in biliary cholesterol-to-bile acid ratio in pregnant hamsters fed low and high levels of cholesterol |
Q44598587 | Influence of newly synthesized cholesterol on bile acid synthesis during chronic inhibition of bile acid absorption |
Q53659466 | Mechanism underlying an elevated serum bile acid level in chronic renal failure patients. |
Q37199631 | Mechanisms of disease: Inborn errors of bile acid synthesis |
Q40783838 | Metabolism of an oxysterol, 7-ketocholesterol, by sterol 27-hydroxylase in HepG2 cells |
Q44119079 | Mice expressing the human CYP7A1 gene in the mouse CYP7A1 knock-out background lack induction of CYP7A1 expression by cholesterol feeding and have increased hypercholesterolemia when fed a high fat diet |
Q45934040 | Monoketocholate can decrease transcellular permeation of methotrexate across Caco-2 cell monolayers and reduce its intestinal absorption in rat. |
Q41845141 | New horizons in the regulation of bile acid and lipid homeostasis: critical role of the nuclear receptor FXR as an intracellular bile acid sensor |
Q33796274 | Nuclear receptor regulation of cholesterol and bile acid metabolism. |
Q37677097 | Orphan nuclear receptor oestrogen-related receptor γ (ERRγ) plays a key role in hepatic cannabinoid receptor type 1-mediated induction of CYP7A1 gene expression |
Q24295748 | Participation of two members of the very long-chain acyl-CoA synthetase family in bile acid synthesis and recycling |
Q34736335 | Potency of individual bile acids to regulate bile acid synthesis and transport genes in primary human hepatocyte cultures |
Q55181509 | Prenatal Exposure to a Maternal High Fat Diet Increases Hepatic Cholesterol Accumulation in Intrauterine Growth Restricted Rats in Part Through MicroRNA-122 Inhibition of Cyp7a1. |
Q44761114 | Programming of initial steps in bile acid synthesis by breast-feeding vs. formula-feeding in the baboon |
Q44296512 | Rapid and improved method for the determination of bile acids in human feces using MS. |
Q40041443 | Recent understanding of cholesterol gallstone pathogenesis: implication to non-surgical therapeutic strategy |
Q44869232 | Regulation of sterol 12alpha-hydroxylase and cholic acid biosynthesis in the rat. |
Q37961649 | Role of dietary proteins and peptides in cardiovascular disease |
Q90760888 | Sheep and cattle exposed to Mycobacterium avium subspecies paratuberculosis exhibit altered total serum cholesterol profiles during the early stages of infection |
Q36197677 | Structural characterization of human cholesterol 7α-hydroxylase |
Q51042606 | Sulfated polysaccharides from Enteromorpha prolifera suppress SREBP-2 and HMG-CoA reductase expression and attenuate non-alcoholic fatty liver disease induced by a high-fat diet. |
Q37575402 | Sulfation of 25-hydroxycholesterol regulates lipid metabolism, inflammatory responses, and cell proliferation |
Q33867812 | Suppression of bile acid synthesis by thyroid hormone in primary human hepatocytes |
Q52541251 | Targeted disruption of the nuclear receptor FXR/BAR impairs bile acid and lipid homeostasis. |
Q34118792 | Targeted inactivation of sister of P-glycoprotein gene (spgp) in mice results in nonprogressive but persistent intrahepatic cholestasis |
Q43781435 | The Diet1 locus confers protection against hypercholesterolemia through enhanced bile acid metabolism |
Q38751170 | The beneficial effects of taurine in preventing metabolic syndrome |
Q38014766 | The effect of taurine on cholesterol metabolism |
Q33896932 | The human liver-specific homolog of very long-chain acyl-CoA synthetase is cholate:CoA ligase |
Q46057040 | The hypocholesterolemic effect of capsaicinoids in ovariectomized rats fed with a cholesterol-free diet was mediated by inhibition of hepatic cholesterol synthesis |
Q46066977 | The mechanism of the cholesterol-lowering effect of water-insoluble fish protein in ovariectomised rats |
Q37251999 | The nonenzymatic reactivity of the acyl-linked metabolites of mefenamic acid toward amino and thiol functional group bionucleophiles |
Q41743620 | The nuclear matrix protein CDP represses hepatic transcription of the human cholesterol-7alpha hydroxylase gene. |
Q36422902 | The solute carrier family SLC10: more than a family of bile acid transporters regarding function and phylogenetic relationships. |
Q41780489 | Transient receptor potential canonical 5 channels plays an essential role in hepatic dyslipidemia associated with cholestasis. |
Q44170609 | Transport of cholesterol into mitochondria is rate-limiting for bile acid synthesis via the alternative pathway in primary rat hepatocytes |
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