Regulation of bile acid biosynthesis

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Regulation of bile acid biosynthesis is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1016/S0889-8553(05)70041-8
P698PubMed publication ID10198776

P2093author name stringR T Stravitz
W M Pandak
Z R Vlahcevic
P2860cites workActivation of the nuclear receptor LXR by oxysterols defines a new hormone response pathwayQ24316367
Transfected human liver cytochrome P-450 hydroxylates vitamin D analogs at different side-chain positionsQ24561465
Frameshift and splice-junction mutations in the sterol 27-hydroxylase gene cause cerebrotendinous xanthomatosis in Jews or Moroccan originQ24564653
The rat hepatic leukemia factor (HLF) gene encodes two transcriptional activators with distinct circadian rhythms, tissue distributions and target preferencesQ24598584
Cloning of the human cholesterol 7 alpha-hydroxylase gene (CYP7) and localization to chromosome 8q11-q12Q28183761
Regulation of bile acid synthesisQ28260543
Circadian transcription of the cholesterol 7 alpha hydroxylase gene may involve the liver-enriched bZIP protein DBPQ28264406
Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXR alphaQ28273937
Molecular cloning of cDNA for vitamin D3 25-hydroxylase from rat liver mitochondriaQ28279965
Molecular cloning and expression of rabbit sterol 12alpha-hydroxylaseQ28298355
Delta 4-3-oxosteroid 5 beta-reductase deficiency described in identical twins with neonatal hepatitis. A new inborn error in bile acid synthesisQ28361181
3 alpha-hydroxysteroid dehydrogenase activity of the Y' bile acid binders in rat liver cytosol. Identification, kinetics, and physiologic significanceQ28361617
Familial giant cell hepatitis associated with synthesis of 3 beta, 7 alpha-dihydroxy-and 3 beta,7 alpha, 12 alpha-trihydroxy-5-cholenoic acidsQ28361624
Bile Acid Synthesis in the Isolated, Perfused Rabbit LiverQ28364763
Suppression of sterol 27-hydroxylase mRNA and transcriptional activity by bile acids in cultured rat hepatocytesQ28368343
Atherosclerosis and sterol 27-hydroxylase: evidence for a role of this enzyme in elimination of cholesterol from human macrophagesQ28369414
A cDNA encoding a rat mitochondrial cytochrome P450 catalyzing both the 26-hydroxylation of cholesterol and 25-hydroxylation of vitamin D3: gonadotropic regulation of the cognate mRNA in ovariesQ28567277
Regulation of the mevalonate pathwayQ29547763
Structural Aspects of Bile Acids Involved in the Regulation of Cholesterol 7alpha-Hydroxylase and Sterol 27-HydroxylaseQ63916805
Effect of lymphatic drainage on 7alpha-hydroxylation of cholesterol in rat liverQ67435250
7 alpha-hydroxylation of 27-hydroxycholesterol in human liver microsomesQ67550110
7α-Hydroxylation of 26-hydroxycholesterol, 3β-hydroxy-5-cholestenoic acid and 3β-hydroxy-5-cholenoic acid by cytochromeP-450 in pig liver microsomesQ67727197
Normal plasma cholesterol in an 88-year-old man who eats 25 eggs a day. Mechanisms of adaptationQ68061644
Effect of thyroid hormone on hepatic cholesterol 7 alpha hydroxylase, LDL receptor, HMG-CoA reductase, farnesyl pyrophosphate synthetase and apolipoprotein A-I mRNA levels in hypophysectomized ratsQ68366770
Potential bile acid precursors in plasma--possible indicators of biosynthetic pathways to cholic and chenodeoxycholic acids in manQ68562278
Control of circadian activity of cholesterol-7 alpha-hydroxylase by glucocorticosteroidsQ69669056
Effect of bile acid feeding on hepatic steroid 12 alpha-hydroxylase activity in hamstersQ70459867
Hepatic cholesterol 7 alpha-hydroxylase activity and serum 7 alpha-hydroxy-cholesterol level during liver regeneration after partial hepatectomy in ratsQ70840962
7 alpha-Hydroxylation of 25-hydroxycholesterol and 27-hydroxycholesterol in human fibroblastsQ72327248
Thyroid hormone rapidly increases cholesterol 7 alpha-hydroxylase mRNA levels in hypophysectomized ratsQ72697049
Effects of bile acids and steroid/thyroid hormones on the expression of cholesterol 7 alpha-hydroxylase mRNA and the CYP7 gene in HepG2 cellsQ72748098
Biliary excretion of cholic acid and cholesterol in hyper-, hypo-, and euthyroid ratsQ73190586
Increased bile acid pool inhibits cholesterol 7 alpha-hydroxylase in cholesterol-fed rabbitsQ73933606
Biliary excretion of bile acids and cholesterol in bile fistula rats; bile acids and steroidsQ74428268
Effects of thyroidectomy and thyroxine treatment on the activity of 12alpha-hydroxylase and of some components of microsomal electron transfer chains in rat liverQ77913530
Excretion of 3beta-hydroxy-5-cholenoic and 3a-hydroxy-5a-cholanoic acids in urine of infants with biliary atresiaQ77916740
Cloning and 5'-flanking sequence of a rat cholesterol 7 alpha-hydroxylase geneQ33192110
Effect of Biliary Drainage on Individual Reactions in the Conversion of Cholesterol to Taurocholic Acid. Bile Acids and Steroids 180Q34054626
Dietary cholesterol and downregulation of cholesterol 7 alpha-hydroxylase and cholesterol absorption in African green monkeysQ34150907
7 alpha hydroxylation of 25-hydroxycholesterol in liver microsomes. Evidence that the enzyme involved is different from cholesterol 7 alpha-hydroxylaseQ34323275
Bile acid synthesis from cholesterol: regulatory and auxiliary pathwaysQ34328308
Identification and characterization of a mouse oxysterol 7alpha-hydroxylase cDNA.Q34439033
Effect of Oral Chenodeoxycholic Acid on Bile Acid Kinetics and Biliary Lipid Composition in Women with CholelithiasisQ34513427
Function and regulation of hydroxylases involved in the bile acid biosynthesis pathwaysQ35600517
Disruption of cholesterol 7alpha-hydroxylase gene in mice. II. Bile acid deficiency is overcome by induction of oxysterol 7alpha-hydroxylase.Q35671417
Adenovirus-mediated transfer of a gene encoding cholesterol 7 alpha-hydroxylase into hamsters increases hepatic enzyme activity and reduces plasma total and low density lipoprotein cholesterolQ35752007
Bile acid biosynthesisQ36136767
Molecular cloning of cDNA for cholesterol 7 alpha-hydroxylase from rat liver microsomes. Nucleotide sequence and expressionQ36243934
Cholesterol and bile acids regulate cholesterol 7 alpha-hydroxylase expression at the transcriptional level in culture and in transgenic mice.Q36651232
Structure of the mouse cholesterol 7 alpha-hydroxylase geneQ36740472
Genomic cloning, sequencing, and analysis of the hamster cholesterol 7 alpha-hydroxylase gene (CYP7).Q36742002
Cholic acid biosynthesis: the enzymatic defect in cerebrotendinous xanthomatosisQ37034717
Unexpected inhibition of cholesterol 7 alpha-hydroxylase by cholesterol in New Zealand white and Watanabe heritable hyperlipidemic rabbits.Q40342532
The P450 superfamily: update on new sequences, gene mapping, accession numbers, early trivial names of enzymes, and nomenclatureQ40484461
Intracellular cholesterol transport and compartmentationQ40554276
Heterogeneous expression of cholesterol 7 alpha-hydroxylase and sterol 27-hydroxylase genes in the rat liver lobulusQ41010263
The opposing effects of retinoic acid and phorbol esters converge to a common response element in the promoter of the rat cholesterol 7 alpha-hydroxylase gene (CYP7A).Q41175415
Bile acid synthesis in humans: regulation of hepatic microsomal cholesterol 7 alpha-hydroxylase activityQ41280585
Transcriptional regulation of the human cholesterol 7.alpha.-hydroxylase geneQ41635456
Cyclosporin A blocks bile acid synthesis in cultured hepatocytes by specific inhibition of chenodeoxycholic acid synthesisQ42023326
Differential feedback regulation of cholesterol 7 alpha-hydroxylase mRNA and transcriptional activity by rat bile acids in primary monolayer cultures of rat hepatocytesQ42161320
Regulation of cholesterol and bile acid homoeostasis in bile-obstructed ratsQ42286090
Transcriptional regulation of the gene encoding cholesterol 7 alpha-hydroxylase in the rat.Q42288372
24-, 25- and 27-hydroxylation of cholesterol by a purified preparation of 27-hydroxylase from pig liverQ42289399
Formation of 7 alpha- and 7 beta-hydroxylated bile acid precursors from 27-hydroxycholesterol in human liver microsomes and mitochondriaQ42289409
A novel nonhepatic hydroxycholesterol 7 alpha-hydroxylase that is markedly stimulated by interleukin-1 beta. Characterization in the immature rat ovaryQ42481640
Characterization of hepatic-specific regulatory elements in the promoter region of the human cholesterol 7alpha-hydroxylase geneQ42528946
Localization of sterol 27-hydroxylase immuno-reactivity in human atherosclerotic plaquesQ42550894
The formation of cholest-5-ene-3 ,26-diol as an intermediate in the conversion of cholesterol into bile acids by liver mitochondriaQ42919405
Down-regulation of the rat hepatic sterol 27-hydroxylase gene by bile acids in transfected primary hepatocytes: possible role of hepatic nuclear factor 1alphaQ44865122
Regulation of bile acid synthesis. II. Effect of bile acid feeding on enzymes regulating hepatic cholesterol and bile acid synthesis in the ratQ45078863
Failure of intravenous infusion of taurocholate to down-regulate cholesterol 7 alpha-hydroxylase in rats with biliary fistulas.Q45084966
Regulation of sterol 27-hydroxylase and an alternative pathway of bile acid biosynthesis in primary cultures of rat hepatocytesQ45096819
Quantitative estimations of the contribution of different bile acid pathways to total bile acid synthesis in the rat.Q45108263
Overexpression of the HDL receptor SR-BI alters plasma HDL and bile cholesterol levelsQ45881945
Structure and nucleotide sequences of the human cholesterol 7 alpha-hydroxylase gene (CYP7).Q48084175
Structure of the rat gene encoding cholesterol 7 alpha-hydroxylaseQ48256658
Hepatic cholesterol metabolism in patients with cholesterol gallstones: enhanced intracellular transport of cholesterolQ50165823
Disruption of cholesterol 7alpha-hydroxylase gene in mice. I. Postnatal lethality reversed by bile acid and vitamin supplementation.Q52519814
Different effects on the expression of CYP7 and CYP27 in rabbit liver by cholic acid and cholestyramine.Q53371746
On the regulation of bile acid formation in the rat liver.Q53759940
Elimination of cholesterol in macrophages and endothelial cells by the sterol 27-hydroxylase mechanism. Comparison with high density lipoprotein-mediated reverse cholesterol transportQ59307006
P433issue1
P304page(s)1-25, v
P577publication date1999-03-01
P1433published inGastroenterology Clinics of North AmericaQ15756082
P1476titleRegulation of bile acid biosynthesis
P478volume28

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