Review article: anthranoid laxatives and their potential carcinogenic effects.

scientific article

Review article: anthranoid laxatives and their potential carcinogenic effects. is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P356DOI10.1046/J.1365-2036.1999.00468.X
P698PubMed publication ID10215727
P5875ResearchGate publication ID13082119

P50authorElisabeth de VriesQ64712784
P2093author name stringJ H Kleibeuker
A Karrenbeld
B A van Gorkom
P2860cites workApoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue KineticsQ24564912
Melanosis coli is associated with an increase in colonic epithelial apoptosis and not with laxative useQ28305744
Mutagenicity of anthraquinone and benzanthrone derivatives in the salmonella/microsome test: Activation of anthraquinone glycosides by enzymic extracts of rat cecal bacteriaQ28324698
Cell death: the significance of apoptosisQ29617620
Melanosis of the rectum in patients with chronic constipation.Q54799112
The effect of rhein and rhein anthrone on intestinal fluid transport and on large intestine transit in germ-free ratsQ56993388
Two-year carcinogenicity study with sennosides in the rat: emphasis on gastro-intestinal alterationsQ72590124
MELANOSIS COLI: A STUDY WITH THE ELECTRON MICROSCOPE.Q33191290
Effect of dietary fibre on stools and the transit-times, and its role in the causation of diseaseQ34202306
Methods for detecting carcinogens and mutagens with the Salmonella/mammalian-microsome mutagenicity testQ34306415
Anthranoid laxative abuse--a risk for colorectal cancer?Q34377402
Epidemiology of cancer of the colon and rectumQ34701839
Evaluation of the potential carcinogenic activity of Senna and Cascara glycosides for the rat colonQ34733019
Effect of irritant purgatives on the myenteric plexus in man and the mouseQ35003336
Induction of intestinal tumours in rats by chrysazinQ35992589
Gastro-intestinal cancer and the use of liquid paraffinQ36039576
The role of chronic constipation, diarrhea, and laxative use in the etiology of large-bowel cancer. Data from the Melbourne Colorectal Cancer StudyQ36453480
An electron-microscope and histochemical study of melanosis coliQ36581308
Anthraquinone laxatives and human cancer: an association in one caseQ36723091
A review of the genetic effects of naturally occurring flavonoids, anthraquinones and related compoundsQ40257471
Pharmacokinetics and metabolism of anthraquinone laxativesQ40619637
Anthraquinone derivatives in vegetable laxativesQ40619665
The senna drug and its chemistryQ40777271
Metabolism and pharmacokinetics of anthranoidsQ40777294
Biosocial correlates of colorectal cancer in GreeceQ41596643
Ultrastructure of mouse intestinal mucosa and changes observed after long term anthraquinone administrationQ42043578
Cell kinetic analysis of the mucosal epithelium and assay of ornithine decarboxylase activity during the process of 1-hydroxyanthraquinone-induced large bowel carcinogenesis in ratsQ42457641
The synergistic effect of 1-hydroxyanthraquinone on methylazoxymethanol acetate-induced carcinogenesis in ratsQ42470929
Carcinogenicity of naturally occurring 1-hydroxyanthraquinone in rats: induction of large bowel, liver and stomach neoplasmsQ42484438
Human aberrant crypt foci with carcinoma in situ from a patient with sporadic colon cancerQ42637286
Colonic and small intestinal response to intravenous prostaglandin F2 alpha and E2 in manQ43248780
The Physiological Basis of Laxative ActionQ43322965
Colorectal cancer and bowel habitsQ43323363
Influence of rhein anthrone and rhein on small intestine transit rate in rats: evidence of prostaglandin mediationQ43941942
Mutagenicity of crude senna and senna glycosides in Salmonella typhimuriumQ44792473
Laxatives: an update on mechanism of actionQ44949914
Melanosis coli: Studies of the toxic effects of irritant purgativesQ45329586
Light and electron-microscopic changes in the colon of the guinea pig after treatment with anthranoid and non-anthranoid laxativesQ46434890
2-Hydroxyemodin, an active metabolite of emodin in the hepatic microsomes of ratsQ50205880
Lack of activity of the bacterial mutagen emodin in HGPRT and SCE assay with V79 Chinese hamster cellsQ50207128
Mutagenicity of anthraquinones in the Salmonella preincubation testQ50211873
Mutagenicity screening of crude drugs with Bacillus subtilis rec-assay and Salmonella/microsome reversion assayQ50214203
Mutagenesis by 9,10-anthraquinone derivatives and related compounds in Salmonella typhimuriumQ50227354
Genotoxicity of naturally occurring hydroxyanthraquinones.Q50466689
Melanosis coli. Prevalence, distribution, and histologic features in 200 consecutive autopsies at Kuopio University Central Hospital.Q50889597
Sennosides do not kill myenteric neurons in the colon of the rat or mouse.Q50891936
Motor dysfunction of the small bowel and colon in patients with the carcinoid syndrome and diarrhea.Q51598634
Rhein Stimulates Active Chloride Secretion in the Short-Circuited Rat Colonic MucosaQ51776478
Effect of Rhein on Electrogenic Chloride Secretion in Rabbit Distal ColonQ53043222
Cell proliferation induced by laxatives and related compounds in the rat intestine.Q53470499
Effect of Intravenous Prostaglandin F2α on Small Intestinal Function in ManQ53883568
Mitochondrial uncoupling activity as a possible base for a laxative and antipsoriatic effect.Q53965310
Influence of rhein on rat colonic Na+,K+-ATPase and permeability in vitro.Q54130824
Retrospective study on laxative use and melanosis coli as risk factors for colorectal neoplasma.Q54650590
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectreview articleQ7318358
P304page(s)443-452
P577publication date1999-04-01
P1433published inAlimentary Pharmacology & TherapeuticsQ4726656
P1476titleReview article: anthranoid laxatives and their potential carcinogenic effects
P478volume13

Reverse relations

cites work (P2860)
Q35769895A Serendipitous Find: A Case of Cholangiocarcinoma Identified Incidentally After Acute Liver Injury Due to Cascara sagrada Ingestion
Q36526028A prospective study of the effect of bowel movement frequency, constipation, and laxative use on colorectal cancer risk
Q37013930Aloe vera non-decolorized whole leaf extract-induced large intestinal tumors in F344 rats share similar molecular pathways with human sporadic colorectal tumors.
Q38778158Aloe vera: A review of toxicity and adverse clinical effects
Q34524655An evaluation of the biological and toxicological properties of Aloe barbadensis (miller), Aloe vera
Q38816745Anthraquinones As Pharmacological Tools and Drugs
Q26749631Anthraquinones and Derivatives from Marine-Derived Fungi: Structural Diversity and Selected Biological Activities
Q59146190Antioxidant and Cytotoxicological Effects of Aloe vera Food Supplements
Q58544147Aquaporins Alteration Profiles Revealed Different Actions of Senna, Sennosides, and Sennoside A in Diarrhea-Rats
Q37908137Are constipation drugs effective and safe to be used in children? A review of the literature
Q92928342Association between anthraquinone laxatives and colorectal cancer: protocol for a systematic review and meta-analysis
Q36331712Astonishing diversity of natural surfactants: 5. Biologically active glycosides of aromatic metabolites
Q40976495Bioconcentration and Metabolism of Emodin in Zebrafish Eleutheroembryos
Q61022808Biological Activity of Quinones
Q33565801CFTR chloride channel as a molecular target of anthraquinone compounds in herbal laxatives
Q33522880Characterization of a novel class of polyphenolic inhibitors of plasminogen activator inhibitor-1
Q34033562Clear evidence of carcinogenic activity by a whole-leaf extract of Aloe barbadensis miller (aloe vera) in F344/N rats
Q35190666Contemporary understanding and management of reflux and constipation in the general population and pregnancy: a consensus meeting
Q42602651Distinguishing characteristics of urothelial carcinoma in kidney transplant recipients between China and Western countries
Q55953114Emodin - a secondary metabolite with multiple ecological functions in higher plants
Q38817374Emodin and Its Role in Chronic Diseases
Q64070859Immunomodulatory Effect of Food Supplement from
Q42514359Inhibition of azoxymethane-induced aberrant crypt foci formation in rat colorectum by whole leaf Aloe arborescens Miller var. natalensis Berger
Q35110306Is Chronic Use of Stimulant Laxatives Harmful to the Colon?
Q24630765Is protein phosphatase inhibition responsible for the toxic effects of okadaic Acid in animals?
Q54458690Is pseudomelanosis coli a marker of colonic neuropathy in severely constipated patients?
Q42362451Melanosis Coli After Long-Term Ingestion of Cape Aloe
Q60046776Melanosis Coli: A Helpful Contrast Effect or a Harmful Pigmentation?
Q38230008Message in a bottle: decoding medication injury patterns in the gastrointestinal tract
Q28302906Myths and misconceptions about chronic constipation
Q35219044Nanocrystalline cerium dioxide efficacy for gastrointestinal motility: potential for prokinetic treatment and prevention in elderly.
Q42923183Phytochemical and laxative studies of Globimetula braunii (Engle) Van Tiegh growing on Cola acuminata (Schott & Endl).
Q57241177Polyethylene glycol enhances colonic barrier function and ameliorates experimental colitis in rats
Q37098809Polyethylene glycol, unique among laxatives, suppresses aberrant crypt foci, by elimination of cells.
Q40396480Portal vein thrombosis related to Cassia angustifolia
Q38202665Potential antineoplastic effects of Aloe-emodin: a comprehensive review
Q46002408Potential risks associated with the use of herbal anti-obesity products.
Q36787973Prospective cohort studies of bowel movement frequency and laxative use and colorectal cancer incidence in US women and men
Q36677868Pseudo-obstruction with pitch black colon--a very rare presentation of melanosis coli.
Q39154995Putative mechanisms of kiwifruit on maintenance of normal gastrointestinal function.
Q34266216Review article: the therapy of constipation
Q73216669Selected bibliography
Q38606135The Genus Aloe: Phytochemistry and Therapeutic Uses Including Treatments for Gastrointestinal Conditions and Chronic Inflammation.
Q36564960The effect of cassia fistula emulsion on pediatric functional constipation in comparison with mineral oil: a randomized, clinical trial
Q50054146The role of gut microbiota in the modulation of drug action: a focus on some clinically significant issues
Q46665339Toxicity and antioxidant capacity of Frangula alnus Mill. bark and its active component emodin
Q35026463Understanding and modulating mammalian-microbial communication for improved human health
Q99630067What we already know about rhubarb: a comprehensive review

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