Alternation in the glycolipid transfer protein expression causes changes in the cellular lipidome

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Alternation in the glycolipid transfer protein expression causes changes in the cellular lipidome is …
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scholarly articleQ13442814

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P819ADS bibcode2014PLoSO...997263K
P356DOI10.1371/JOURNAL.PONE.0097263
P932PMC publication ID4019525
P698PubMed publication ID24824606
P5875ResearchGate publication ID262305009

P50authorPeter MattjusQ46967043
P2093author name stringMatti A Kjellberg
Anders P E Backman
Henna Ohvo-Rekilä
P2860cites workProtein measurement with the Folin phenol reagentQ20900776
Molecular cloning of globotriaosylceramide/CD77 synthase, a glycosyltransferase that initiates the synthesis of globo series glycosphingolipidsQ22253437
Molecular machinery for non-vesicular trafficking of ceramideQ24302195
Identification of a family of animal sphingomyelin synthasesQ24302262
Glycosphingolipid synthesis requires FAPP2 transfer of glucosylceramideQ24337032
FAPPs control Golgi-to-cell-surface membrane traffic by binding to ARF and PtdIns(4)PQ24337930
Oxysterol-binding protein and vesicle-associated membrane protein-associated protein are required for sterol-dependent activation of the ceramide transport proteinQ24547407
Regulation of oxysterol-binding protein Golgi localization through protein kinase D-mediated phosphorylationQ24625904
Structural basis for glycosphingolipid transfer specificityQ24654053
Casein kinase I{gamma}2 down-regulates trafficking of ceramide in the synthesis of sphingomyelinQ24654811
Regulation of secretory transport by protein kinase D-mediated phosphorylation of the ceramide transfer proteinQ24682866
The complexity of sphingolipid biosynthesis in the endoplasmic reticulumQ26823045
The role of phospholipids in the biological activity and structure of the endoplasmic reticulumQ27008152
Crystal structures of the CERT START domain with inhibitors provide insights into the mechanism of ceramide transferQ27658781
Formation and function of phosphatidylserine and phosphatidylethanolamine in mammalian cellsQ28274690
Glycolipid transfer proteins and membrane interactionQ28300786
LASS5 is a bona fide dihydroceramide synthase that selectively utilizes palmitoyl-CoA as acyl donorQ28506699
Coordinated lipid transfer between the endoplasmic reticulum and the Golgi complex requires the VAP proteins and is essential for Golgi-mediated transportQ30483267
Quantitative profiling of phospholipids by multiple precursor ion scanning on a hybrid quadrupole time-of-flight mass spectrometerQ30700823
Human glycolipid transfer protein (GLTP) expression modulates cell shapeQ33916757
The intermembrane ceramide transport catalyzed by CERT is sensitive to the lipid environment.Q54378609
Binding of verocytotoxin 1 to its receptor is influenced by differences in receptor fatty acid contentQ54683456
Automated Identification and Quantification of Glycerophospholipid Molecular Species by Multiple Precursor Ion ScanningQ57364873
Charting molecular composition of phosphatidylcholines by fatty acid scanning and ion trap MS3fragmentationQ57375067
Changes in composition of newly synthesized sphingolipids of HeLa cells during the cell cycle -- suppression of sphingomyelin and higher-glycosphingolipid synthesis and accumulation of ceramide and glucosylceramide in mitotic cellsQ73881444
Analysis of the key elements of FFAT-like motifs identifies new proteins that potentially bind VAP on the ER, including two AKAPs and FAPP2.Q34140627
Ceramide synthases: roles in cell physiology and signalingQ34141622
A unique mitochondria-associated membrane fraction from rat liver has a high capacity for lipid synthesis and contains pre-Golgi secretory proteins including nascent lipoproteinsQ34325693
CERT mediates intermembrane transfer of various molecular species of ceramides.Q34376027
Maintenance of the diacylglycerol level in the Golgi apparatus by the Nir2 protein is critical for Golgi secretory function.Q34396325
Human glycolipid transfer protein gene (GLTP) expression is regulated by Sp1 and Sp3: involvement of the bioactive sphingolipid ceramideQ34488985
When do Lasses (longevity assurance genes) become CerS (ceramide synthases)?: Insights into the regulation of ceramide synthesisQ34541094
The VAP protein family: from cellular functions to motor neuron diseaseQ34777648
Glycolipid transfer protein expression is affected by glycosphingolipid synthesis.Q34876081
Knockout of Arabidopsis accelerated-cell-death11 encoding a sphingosine transfer protein causes activation of programmed cell death and defenseQ35005430
The ether lipid precursor hexadecylglycerol causes major changes in the lipidome of HEp-2 cellsQ35010145
Inactivation of the Podospora anserina vegetative incompatibility locus het-c, whose product resembles a glycolipid transfer protein, drastically impairs ascospore productionQ35542286
Enzymatic synthesis of Gb3 and iGb3 ceramides.Q35767520
Sphingolipidomics: high-throughput, structure-specific, and quantitative analysis of sphingolipids by liquid chromatography tandem mass spectrometryQ36127968
Molecular mechanisms and regulation of ceramide transportQ36133985
High-throughput shotgun lipidomics by quadrupole time-of-flight mass spectrometryQ37415000
High throughput quantitative molecular lipidomicsQ37902290
Co-evolution of sphingomyelin and the ceramide transport protein CERT.Q38120926
Membranes and mammalian glycolipid transferring proteins.Q38162052
Vesicular and non-vesicular transport feed distinct glycosylation pathways in the GolgiQ39115655
Pre- and post-Golgi translocation of glucosylceramide in glycosphingolipid synthesis.Q39751424
Sphingolipid uptake by cultured cells: complex aggregates of cell sphingolipids with serum proteins and lipoproteins are rapidly catabolized.Q40490817
Role of multiple drug resistance protein 1 in neutral but not acidic glycosphingolipid biosynthesisQ40609398
[14C]serine from phosphatidylserine labels ceramide and sphingomyelin in L929 cells: evidence for a new metabolic relationship between glycerophospholipids and sphingolipidsQ40673753
Glucosylceramide is synthesized at the cytosolic surface of various Golgi subfractionsQ41632006
Determination of the intracellular sites and topology of glucosylceramide synthesis in rat liverQ41950312
Quantitative analysis of phospholipids by thin-layer chromatographyQ42959176
The mitochondria-associated endoplasmic-reticulum subcompartment (MAM fraction) of rat liver contains highly active sphingolipid-specific glycosyltransferasesQ43002828
The glycolipid transfer protein interacts with the vesicle-associated membrane protein-associated protein VAP-A.Q43295626
Identification of a glycosphingolipid transfer protein GLTP1 in Arabidopsis thaliana.Q46529623
Human glycolipid transfer protein--intracellular localization and effects on the sphingolipid synthesisQ46916222
High throughput quantification of cholesterol and cholesteryl ester by electrospray ionization tandem mass spectrometry (ESI-MS/MS).Q46928125
Long-term performance and stability of molecular shotgun lipidomic analysis of human plasma samplesQ47848884
Glycolipid transfer protein from pig brain transfers glycolipids with beta-linked sugars but not with alpha-linked sugars at the sugar-lipid linkage.Q48265615
Properties of a specific glycolipid transfer protein from bovine brain.Q48460671
A modified procedure for thin-layer chromatography of phospholipids.Q48864278
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue5
P407language of work or nameEnglishQ1860
P304page(s)e97263
P577publication date2014-05-13
P1433published inPLOS OneQ564954
P1476titleAlternation in the glycolipid transfer protein expression causes changes in the cellular lipidome
P478volume9

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cites work (P2860)
Q60302246Glucosylceramide acyl chain length is sensed by the glycolipid transfer protein
Q88035802MicroRNA 196B Regulates HOXA5, HOXB6 and GLTP Expression Levels in Colorectal Cancer Cells
Q64108493Proteomics of the corpus callosum to identify novel factors involved in hypomyelinated Niemann-Pick Type C disease mice
Q47976198Purification and Validation of Lipid Transfer Proteins.
Q38266425Sphingolipid metabolism and interorganellar transport: localization of sphingolipid enzymes and lipid transfer proteins
Q36406344Sphingolipid transfer proteins defined by the GLTP-fold
Q92081718Sphingolipid-Transporting Proteins as Cancer Therapeutic Targets
Q93345471Upregulation of human glycolipid transfer protein (GLTP) induces necroptosis in colon carcinoma cells

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