| review article | Q7318358 |
| scholarly article | Q13442814 |
| P356 | DOI | 10.1016/S1081-1206(10)63281-4 |
| P698 | PubMed publication ID | 10227331 |
| P2093 | author name string | Ahmed AR | |
| Lalani T | |||
| Simmons RK | |||
| P2860 | cites work | Cloning of cDNA for human T-cell replacing factor (interleukin-5) and comparison with the murine homologue | Q24295260 |
| Expression cloning of the human IL-3 receptor cDNA reveals a shared beta subunit for the human IL-3 and GM-CSF receptors | Q24309058 | ||
| Molecular cloning, nucleotide sequence, and expression of the gene encoding human eosinophil differentiation factor (interleukin 5) | Q24594391 | ||
| Interleukin 5 synthesis by eosinophils: association with granules and immunoglobulin-dependent secretion | Q24680147 | ||
| Purified interleukin 5 supports the terminal differentiation and proliferation of murine eosinophilic precursors | Q24682536 | ||
| Murine eosinophil differentiation factor. An eosinophil-specific colony-stimulating factor with activity for human cells | Q24682893 | ||
| A novel dimer configuration revealed by the crystal structure at 2.4 A resolution of human interleukin-5 | Q27732152 | ||
| Interleukin-4, -5, and -6 and tumor necrosis factor-alpha in normal and asthmatic airways: evidence for the human mast cell as a source of these cytokines | Q28253247 | ||
| Identification of a Cys motif in the common beta chain of the interleukin 3, granulocyte-macrophage colony-stimulating factor, and interleukin 5 receptors essential for disulfide-linked receptor heterodimerization and activation of all three recepto | Q28258401 | ||
| Recombinant interferon gamma therapy for atopic dermatitis | Q28266125 | ||
| Critical cytoplasmic domains of the common beta subunit of the human GM-CSF, IL-3 and IL-5 receptors for growth signal transduction and tyrosine phosphorylation | Q28608970 | ||
| The mechanism of action of cyclosporin A and FK506 | Q30014847 | ||
| Interleukin 5 (IL-5) provides a signal that is required in addition to IL-4 for isotype switching to immunoglobulin (Ig) G1 and IgE | Q30435016 | ||
| Interleukin 5 and interleukin 2 cooperate with interleukin 4 to induce IgG1 secretion from anti-Ig-treated B cells | Q30442732 | ||
| The biological role of interleukin 5. | Q33351960 | ||
| Cloning of complementary DNA encoding T-cell replacing factor and identity with B-cell growth factor II. | Q34162731 | ||
| The eosinophilic leukocyte: structure and function | Q34182912 | ||
| Identification of thyroid stimulating hormone receptor-specific T cells in Graves' disease thyroid using autoantigen-transfected Epstein-Barr virus-transformed B cell lines. | Q35749842 | ||
| Prednisolone treatment in asthma is associated with modulation of bronchoalveolar lavage cell interleukin-4, interleukin-5, and interferon-gamma cytokine gene expression | Q72860726 | ||
| Relationships among numbers of bronchoalveolar lavage cells expressing messenger ribonucleic acid for cytokines, asthma symptoms, and airway methacholine responsiveness in atopic asthma | Q72900769 | ||
| The role of eosinophils in the pathobiology of Hodgkin's disease | Q73481560 | ||
| Eosinophilia and intracranial worm recovery in interleukin-5 transgenic and interleukin-5 receptor α chain-knockout mice infected with Angiostrongylus cantonensis | Q73485194 | ||
| IL-5 synthesis is upregulated in human nasal polyp tissue1 | Q73493393 | ||
| Effects of rapamycin, cyclosporin A, and dexamethasone on interleukin 5-induced eosinophil degranulation and prolonged survival | Q73954087 | ||
| Interleukin-12 inhibits production of interleukin-5 but not of granulocyte/macrophage colony-stimulating factor by antigen-stimulated blood mononuclear cells in allergic bronchial asthmatics | Q74046798 | ||
| Granulocyte-macrophage colony-stimulating factor and IL-5 activate mitogen-activated protein kinase through Jak2 kinase and phosphatidylinositol 3-kinase in human eosinophils | Q74082215 | ||
| Interleukin 5 signals through Shc and Grb2 in human eosinophils | Q74111166 | ||
| Correlation of house dust mite-specific lymphocyte proliferation with IL-5 production, eosinophilia, and the severity of symptoms in infants with atopic dermatitis | Q74116731 | ||
| IL-4- and IL-5-positive T lymphocytes, eosinophils, and mast cells in allergen-induced late-phase cutaneous reactions in atopic subjects | Q74310705 | ||
| Prostaglandin E2 differentially modulates IL-5 gene expression in activated human T lymphocytes depending on the costimulatory signal | Q74310710 | ||
| Increased serum concentration of interleukin-5 in patients with Graves' disease and Hashimoto's thyroiditis | Q74450244 | ||
| Evidence that eosinophil infiltration in the OK-432/fibrinogen-injected Meth-A tumor in mice is mediated by locally produced IL-5 | Q74501909 | ||
| Interleukin-5 mRNA stability in human T cells is regulated differently than interleukin-2, interleukin-3, interleukin-4, granulocyte/macrophage colony-stimulating factor, and interferon-gamma | Q74503183 | ||
| Th2-like cytokine activity in dermatitis herpetiformis | Q74592519 | ||
| Eosinophils, bronchial hyperreactivity and late-phase asthmatic reactions | Q93630485 | ||
| Human lung mast cell IL-5 gene and protein expression: temporal analysis of upregulation following IgE-mediated activation | Q93864369 | ||
| Messenger RNA expression of the cytokine gene cluster, interleukin 3 (IL-3), IL-4, IL-5, and granulocyte/macrophage colony-stimulating factor, in allergen-induced late-phase cutaneous reactions in atopic subjects | Q36229928 | ||
| Identification of a lymphokine that stimulates eosinophil differentiation in vitro. Its relationship to interleukin 3, and functional properties of eosinophils produced in cultures | Q36350409 | ||
| Interleukin 5 modifies histamine release and leukotriene generation by human basophils in response to diverse agonists | Q36354173 | ||
| Highly purified murine interleukin 5 (IL-5) stimulates eosinophil function and prolongs in vitro survival. IL-5 as an eosinophil chemotactic factor | Q36354998 | ||
| The intracellular signal transduction mechanism of interleukin 5 in eosinophils: the involvement of lyn tyrosine kinase and the Ras-Raf-1-MEK-microtubule-associated protein kinase pathway | Q36364828 | ||
| Interleukin 5 deficiency abolishes eosinophilia, airways hyperreactivity, and lung damage in a mouse asthma model | Q36366104 | ||
| Molecular Events Mediating T Cell Activation | Q36578210 | ||
| Confocal laser scanning microscopic and immunoelectron microscopic studies of the anatomical distribution of fibrillar IgA deposits in dermatitis herpetiformis | Q36779711 | ||
| A functional bipartite nuclear localisation signal in the cytokine interleukin-5. | Q36858506 | ||
| Regulation and biological function of helminth-induced cytokine responses | Q37094111 | ||
| Tumour-associated eosinophilia: a review | Q37096566 | ||
| Recombinant interferon-alpha selectively inhibits the production of interleukin-5 by human CD4+ T cells | Q37350150 | ||
| Suppression of in vivo polyclonal IgE responses by monoclonal antibody to the lymphokine B-cell stimulatory factor 1. | Q37412303 | ||
| Asthma and inflammation | Q37712415 | ||
| Assessment of cytokines by immunofluorescence and the paraformaldehyde-saponin procedure | Q37745396 | ||
| Eosinophils are the major effector cells of immunity to microfilariae in a mouse model of onchocerciasis | Q39007355 | ||
| Combinations of interleukins 2, 4 and 5 regulate the secretion of murine immunoglobulin isotypes | Q39521898 | ||
| Allergen-specific human T cell clones produce interleukin-5 upon stimulation with the Th1 cytokine interleukin-2. | Q40445701 | ||
| Inhibition of pulmonary eosinophilia and hyperreactivity by antibodies to interleukin-5. | Q40445772 | ||
| Characterization of the mouse granulocyte-macrophage colony-stimulating factor (GM-CSF) gene promoter: nuclear factors that interact with an element shared by three lymphokine genes--those for GM-CSF, interleukin-4 (IL-4), and IL-5. | Q40642206 | ||
| The biology of interleukin-5 and its receptor. | Q40860972 | ||
| Hodgkin's disease: a cytokine-producing tumor--a review | Q40921657 | ||
| Interleukin-5 binds to heparin/heparan sulfate. A model for an interaction with extracellular matrix | Q41058692 | ||
| Biology of interleukin-5 and its relevance to allergic disease | Q41062106 | ||
| The activation of the JAK2/STAT5 pathway is commonly involved in signaling through the human IL-5 receptor | Q41080230 | ||
| Cyclosporin A and FK506 reduce interleukin-5 mRNA abundance by inhibiting gene transcription | Q41096837 | ||
| Suppression of interleukin-2 and interleukin-2 receptor biosynthesis by gold compounds in in vitro activated human peripheral blood mononuclear cells | Q41575613 | ||
| Inhibition of interleukin-5 with a monoclonal antibody attenuates allergic inflammation | Q41585449 | ||
| Role of the C-terminus in the biological activity of human interleukin 5 | Q41673676 | ||
| Analysis of three human interleukin 5 structures suggests a possible receptor binding mechanism | Q41737199 | ||
| Enhancement of human basophil histamine release by interleukin 5 | Q42099445 | ||
| Transforming growth factor beta abrogates the effects of hematopoietins on eosinophils and induces their apoptosis | Q42205820 | ||
| Requirement of Lyn and Syk tyrosine kinases for the prevention of apoptosis by cytokines in human eosinophils | Q42943439 | ||
| Onchocerciasis and immunity in humans: enhanced T cell responsiveness to parasite antigen in putatively immune individuals | Q43448197 | ||
| Defining protective responses to pathogens: cytokine profiles in leprosy lesions | Q43702135 | ||
| Mutated interleukin-5 monomers are biologically inactive | Q44055276 | ||
| Inhibitory effect of the TRFK-5 anti-IL-5 antibody in a guinea pig model of asthma | Q46610552 | ||
| Inhibitory effect of F-1322 on allergic eosinophil infiltration in airways | Q46888120 | ||
| Bronchial reactivities to acetylcholine and IgE levels in asthmatic subjects after long-term remissions | Q47862740 | ||
| New directions in understanding interleukin-5 gene expression | Q48011177 | ||
| Ablation of eosinophils with anti-IL-5 antibody enhances the survival of intracranial worms of Angiostrongylus cantonensis in the mouse | Q48273722 | ||
| Airways inflammation in nocturnal asthma | Q48910207 | ||
| Inhibitory effect of cetirizine on cytokine-enhanced in vitro eosinophil survival. | Q50528236 | ||
| Gold sodium thiomalate selectivity inhibits interleukin-5-mediated eosinophil survival. | Q50759471 | ||
| T lymphocytes in lesional skin of patients with dermatitis herpetiformis. | Q52055774 | ||
| Expression of interleukin-5 by human bone marrow microvascular endothelial cells: implications for the regulation of eosinophilopoiesis in vivo. | Q52191198 | ||
| Recombinant human interleukin 5 is an eosinophil differentiation factor but has no activity in standard human B cell growth factor assays | Q58862697 | ||
| Interleukin-5 Messenger RNA and Immunoreactive Protein Expression by Activated Eosinophils in Lesional Atopic Dermatitis Skin | Q59413220 | ||
| In vitro anti-tumor activity of eosinophils from cancer patients treated with subcutaneous administration of interleukin 2. Role of interleukin 5 | Q61693070 | ||
| Expression and function of the Fas receptor on human blood and tissue eosinophils | Q61959869 | ||
| Recombinant gamma interferon in treatment of patients with atopic dermatitis and elevated IgE levels | Q67285108 | ||
| Engineering Antibodies for Therapy | Q67470988 | ||
| Increased immunoreactive interleukin-5 levels in blister fluids of bullous pemphigoid | Q67587752 | ||
| Cytokine receptors and signal transduction | Q68132796 | ||
| Induction of antibody synthesis by CD4+ T cells: IL 5 is essential for induction of antigen-specific antibody responses by TH2 but not TH1 clones | Q68162329 | ||
| Structure of recombinant human interleukin 5 produced by Chinese hamster ovary cells | Q68834664 | ||
| Recombinant human interleukin 5 is a selective eosinophil chemoattractant | Q69506407 | ||
| Malignant tumor and eosinophils. I. Prognostic significance in gastric cancer | Q69587598 | ||
| Characterization of the human IL-5 receptors on eosinophils | Q70138650 | ||
| Respiratory burst of normal human eosinophils | Q70175812 | ||
| Bullous pemphigoid: A cause of peripheral blood eosinophilia | Q70263888 | ||
| Inhibition of in vitro proliferative response of cultured T lymphocytes to interleukin-2 by gold sodium thiomalate | Q70380360 | ||
| Human interleukin-5 induces staphylococcal A Cowan 1 strain-activated human B cells to secrete IgM | Q70567383 | ||
| Juvenile Diabetes Mellitus and Atopy | Q70671737 | ||
| Nasal polyps--a model of chronic respiratory mucosal inflammation | Q70786288 | ||
| Strongyloides stercoralis: eosinophil-dependent immune-mediated killing of third stage larvae in BALB/cByJ mice | Q71080603 | ||
| Regulation of disease susceptibility: decreased prevalence of IgE-mediated allergic disease in patients with multiple sclerosis | Q71120328 | ||
| Eosinophilic pustular folliculitis effectively treated with recombinant interferon-gamma: suppression of mRNA expression of interleukin 5 in peripheral blood mononuclear cells | Q71330509 | ||
| Different cytokine mRNA profiles in Graves' disease, Hashimoto's thyroiditis, and nonautoimmune thyroid disorders determined by quantitative reverse transcriptase polymerase chain reaction (RT-PCR) | Q71331630 | ||
| Direct measurement of cytokines (IFN-gamma, IL-4, -5, and -6) from organs after antigenic challenge | Q71754643 | ||
| Eosinophil infiltration precedes development of airway hyperreactivity and mucosal exudation after intranasal administration of interleukin-5 to mice | Q71922369 | ||
| Effects of an antibody to interleukin-5 in a monkey model of asthma | Q71954025 | ||
| Involvement of IL-5 in a murine model of allergic pulmonary inflammation: prophylactic and therapeutic effect of an anti-IL-5 antibody | Q72007976 | ||
| Clinical significance of measuring levels of sputum and serum ECP and serum IL-5 in bronchial asthma | Q72246101 | ||
| Electron microscopic study of dermatitis herpetiformis | Q72335066 | ||
| Antibody to interleukin 5 prevents blood and tissue eosinophilia but not liver trapping in murine larval toxocariasis | Q72597200 | ||
| Histamine increases anti-CD3 induced IL-5 production of TH2-type T cells via histamine H2-receptors | Q72604488 | ||
| Cytokines in the peritoneal fluid of patients with endometriosis | Q72665342 | ||
| Allergen-induced changes in bone marrow progenitors and airway responsiveness in dogs and the effect of inhaled budesonide on these parameters | Q72769846 | ||
| P433 | issue | 4 | |
| P304 | page(s) | 317-32; quiz 332-3 | |
| P577 | publication date | 1999-04-01 | |
| P1433 | published in | Annals of Allergy, Asthma & Immunology | Q13429696 |
| P1476 | title | Biology of IL-5 in health and disease | |
| P478 | volume | 82 |
| Q45415273 | A T2 cytokine environment may not limit T1 responses in human immunodeficiency virus patients with a favourable response to antiretroviral therapy |
| Q33883632 | Advances in immunopharmacology of asthma |
| Q34014352 | Asthma: where beyond steroids? |
| Q50235175 | Beware the "red herring". |
| Q40237834 | Differential engagement of modules 1 and 4 of vascular cell adhesion molecule-1 (CD106) by integrins alpha4beta1 (CD49d/29) and alphaMbeta2 (CD11b/18) of eosinophils |
| Q36608105 | Genome-wide expression profiles identify potential targets for gene-environment interactions in asthma severity |
| Q36076384 | Inhibitory effect of heparin-derived oligosaccharides on secretion of interleukin-4 and interleukin-5 from human peripheral blood T lymphocytes |
| Q37958696 | Innate and adaptive immunity to the nematode Strongyloides stercoralis in a mouse model. |
| Q36955887 | Roles of integrin activation in eosinophil function and the eosinophilic inflammation of asthma |
| Q46609922 | Serum interleukin-5 measurements for monitoring acute asthma in children |
| Q28552440 | The Immunomodulatory Role of Adjuvants in Vaccines Formulated with the Recombinant Antigens Ov-103 and Ov-RAL-2 against Onchocerca volvulus in Mice |
| Q34881155 | Treating the allergic patient: think globally, treat globally |
| Q38587334 | Update on reslizumab for eosinophilic asthma |
| Q37838791 | Update on strongyloidiasis in the immunocompromised host |
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