Inflammatory response in islet transplantation

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Inflammatory response in islet transplantation is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1155/2014/451035
P932PMC publication ID4021753
P698PubMed publication ID24883060
P5875ResearchGate publication ID262781557

P50authorMorihito TakitaQ59191703
Marlon F LevyQ91479902
Bashoo NaziruddinQ91479906
P2093author name stringMichael C Lawrence
Faisal Kunnathodi
Mazhar A Kanak
P2860cites workImprovement of human islet cryopreservation by a p38 MAPK inhibitorQ46568676
Requirements of calcium fluxes and ERK kinase activation for glucose- and interleukin-1beta-induced beta-cell apoptosisQ46580612
Islet transplantation in type 1 diabetes mellitus using cultured islets and steroid-free immunosuppression: Miami experienceQ46582092
Insulin alters cytokine content in two pivotal organs after brain death: a porcine modelQ46639251
Islet transplantation outcomes in mice are better with fresh islets and exendin-4 treatmentQ46678794
Improved metabolic control and quality of life in seven patients with type 1 diabetes following islet after kidney transplantationQ46687469
Low molecular weight dextran sulfate: a strong candidate drug to block IBMIR in clinical islet transplantationQ46903624
Inhibition of p38 pathway suppresses human islet production of pro-inflammatory cytokines and improves islet graft function.Q47622122
Response of Encapsulated Rat Pancreatic Islets to HypoxiaQ47672854
Comparison of Fresh and Cultured Islets From Human and Porcine PancreataQ48096761
The effect of selective neutrophil elastase inhibitor on pancreatic islet yields and functions in rat with hypercytokinemia.Q48735212
Elevated levels of interleukin-8 in donor lungs is associated with early graft failure after lung transplantationQ49018255
Evidence for Induced Expression of HLA Class II on Human Islets: Possible Mechanism for HLA Sensitization in Transplant Recipients.Q51754090
Incompatibility between human blood and isolated islets of Langerhans: a finding with implications for clinical intraportal islet transplantation?Q52536571
The effect of composite pig islet-human endothelial cell grafts on the instant blood-mediated inflammatory reaction.Q53507473
Nitric oxide mediates cytokine-induced inhibition of insulin secretion by human islets of LangerhansQ24314701
Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimenQ28141785
Stable expression of manganese superoxide dismutase (MnSOD) in insulinoma cells prevents IL-1beta- induced cytotoxicity and reduces nitric oxide productionQ28379504
Regulation and function of NF-kappaB transcription factors in the immune systemQ29616427
HLA class I sensitization in islet transplant recipients: report from the Collaborative Islet Transplant RegistryQ30405787
Improvement in outcomes of clinical islet transplantation: 1999-2010.Q30418470
Current status of immunomodulatory and cellular therapies in preclinical and clinical islet transplantationQ30430008
OPTN/SRTR 2011 Annual Data Report: pancreasQ30581468
Analysis of beta-cell gene expression reveals inflammatory signaling and evidence of dedifferentiation following human islet isolation and cultureQ31047685
Synergistic activation of NF-kappab and inducible isoform of nitric oxide synthase induction by interferon-gamma and tumor necrosis factor-alpha in INS-1 cellsQ31386037
A novel C5a receptor-tissue factor cross-talk in neutrophils links innate immunity to coagulation pathways.Q53598537
Composite islet-endothelial cell grafts: a novel approach to counteract innate immunity in islet transplantation.Q53654471
Low antioxidant enzyme gene expression in pancreatic islets compared with various other mouse tissues.Q53787751
Auto- and alloimmune reactivity to human islet allografts transplanted into type 1 diabetic patients.Q53845716
Chronic pancreatitisQ56627343
Intracellular Stress Signaling Pathways Activated During Human Islet Preparation and Following Acute Cytokine ExposureQ57398169
HLA class II induction in human islet cells by interferon-γ plus tumour necrosis factor or lymphotoxinQ59083904
Islet Autotransplant Outcomes After Total Pancreatectomy: A Contrast to Islet Allograft OutcomesQ61651168
ENDOTOXIN CONTAMINATION MAY BE RESPONSIBLE FOR THE UNEXPLAINED FAILURE OF HUMAN PANCREATIC ISLET TRANSPLANTATION1Q61995626
Nuclear Factor κB Protects Pancreatic β-Cells From Tumor Necrosis Factor-α-Mediated ApoptosisQ64377783
The transgenic expression of human CD39 on murine islets inhibits clotting of human blood.Q64895051
Effect of transplantation site on the results of pancreatic islet isografts in diabetic ratsQ67273573
Cytotoxic effect of IFN-gamma plus TNF-alpha on human islet cellsQ67996902
Cytotoxicity of human pI 7 interleukin-1 for pancreatic islets of LangerhansQ70291006
The role of nitric oxide in IL-1 beta-mediated dysfunction of rodent islets of Langerhans. Implications for the function of intrahepatic islet graftsQ72409802
Modulation of JNK and p38 stress activated protein kinases in isolated islets of Langerhans: insulin as an autocrine survival signalQ73352727
Identification of novel cytokine-induced genes in pancreatic beta-cells by high-density oligonucleotide arraysQ73831600
Genetic deletion of chemokine receptor CXCR3 or antibody blockade of its ligand IP-10 modulates posttransplantation graft-site lymphocytic infiltrates and prolongs functional graft survival in pancreatic islet allograft recipientsQ73881896
Tumor necrosis factor-alpha is expressed in donor heart and predicts right ventricular failure after human heart transplantationQ74014433
Tissue factor: an enzyme cofactor and a true receptorQ74315010
Transplantation of allogeneic islets of Langerhans in the rat liver: effects of macrophage depletion on graft survival and microenvironment activationQ74371114
Thrombin perturbs neurite outgrowth and induces apoptotic cell death in enriched chick spinal motoneuron cultures through caspase activationQ77125943
Interleukin-8 release during early reperfusion predicts graft function in human lung transplantationQ77487113
Why do microencapsulated islet grafts fail in the absence of fibrotic overgrowth?Q77948203
Activation and expression of ERK, JNK, and p38 MAP-kinases in isolated islets of Langerhans: implications for cultured islet survivalQ78099795
Production of tissue factor by pancreatic islet cells as a trigger of detrimental thrombotic reactions in clinical islet transplantationQ78724482
Activation of c-Jun NH2-terminal kinase (JNK) pathway during islet transplantation and prevention of islet graft loss by intraportal injection of JNK inhibitorQ79563979
Pathophysiology of chronic pancreatitisQ80134001
Chronic pancreatitisQ80231426
Alloreactivity against repeated HLA mismatches of sequential islet grafts transplanted in non-uremic type 1 diabetes patientsQ80346010
Improving efficacy of clinical islet transplantation with iodixanol-based islet purification, thymoglobulin induction, and blockage of IL-1β and TNF-αQ83591286
Correlation of released HMGB1 levels with the degree of islet damage in mice and humans and with the outcomes of islet transplantation in miceQ84040421
Immune cell populations in nonhuman primate isletsQ84340259
Withaferin A inhibits pro-inflammatory cytokine-induced damage to islets in culture and following transplantationQ85896039
Evidence for instant blood-mediated inflammatory reaction in clinical autologous islet transplantationQ87137462
Markedly decreased oxygen tension in transplanted rat pancreatic islets irrespective of the implantation siteQ31879740
Measurements of oxygen tension in native and transplanted rat pancreatic isletsQ32058693
Genetic engineering of a suboptimal islet graft with A20 preserves beta cell mass and functionQ33187317
Multiple chromatin-bound protein kinases assemble factors that regulate insulin gene transcriptionQ33564350
Elevation of high-mobility group box 1 after clinical autologous islet transplantation and its inverse correlation with outcomesQ33894332
Regulation of CCAAT/enhancer-binding protein homologous protein (CHOP) expression by interleukin-1 beta in pancreatic beta cellsQ33924202
Alleviation of instant blood-mediated inflammatory reaction in autologous conditions through treatment of human islets with NF-κB inhibitorsQ34387239
Calcineurin/nuclear factor of activated T cells and MAPK signaling induce TNF-{alpha} gene expression in pancreatic islet endocrine cellsQ34488816
Natural history of intrahepatic canine islet cell autograftsQ34546886
Secretory products of macrophagesQ34557411
Calcineurin/NFAT signalling regulates pancreatic beta-cell growth and functionQ34567627
Islet transplantation for brittle type 1 diabetes: the UIC protocolQ34774804
Prolonged insulin independence after islet allotransplants in recipients with type 1 diabetesQ35032883
Prolyl hydroxylase-1 negatively regulates IkappaB kinase-beta, giving insight into hypoxia-induced NFkappaB activityQ35141643
NF-kappa B prevents beta cell death and autoimmune diabetes in NOD miceQ35629489
Inflammation-mediated dysfunction and apoptosis in pancreatic islet transplantation: implications for intrahepatic graftsQ36053215
Update on islet transplantationQ36065843
Potent induction immunotherapy promotes long-term insulin independence after islet transplantation in type 1 diabetesQ36077883
Evidence that hypoxia markers detect oxygen gradients in liver: pimonidazole and retrograde perfusion of rat liverQ36081607
Determinants of the selective toxicity of alloxan to the pancreatic B cellQ36280972
CXCR1/2 inhibition enhances pancreatic islet survival after transplantationQ36290283
Chemokine receptors and transplantationQ36347945
Intraislet release of interleukin 1 inhibits beta cell function by inducing beta cell expression of inducible nitric oxide synthaseQ36364369
Pancreatic beta cell-specific expression of thioredoxin, an antioxidative and antiapoptotic protein, prevents autoimmune and streptozotocin-induced diabetesQ36404284
Heme oxygenase 1 is required for mammalian iron reutilizationQ36601831
Reduced stress defense in heme oxygenase 1-deficient cells.Q36601994
Neonatal β cell development in mice and humans is regulated by calcineurin/NFATQ36655088
Formation of composite endothelial cell-mesenchymal stem cell islets: a novel approach to promote islet revascularizationQ36842592
Chromatin-bound mitogen-activated protein kinases transmit dynamic signals in transcription complexes in beta-cellsQ36869826
NF-kappaB and cancer-identifying targets and mechanismsQ36984251
Improvement in β-cell secretory capacity after human islet transplantation according to the CIT07 protocolQ37031038
Autologous pancreatic islet transplantation in human bone marrow.Q37193323
Interdependent roles for hypoxia inducible factor and nuclear factor-kappaB in hypoxic inflammation.Q37206832
Acute antibody-mediated complement activation mediates lysis of pancreatic islets cells and may cause tissue loss in clinical islet transplantationQ37217407
IKK/NF-kappaB signaling in intestinal epithelial cells controls immune homeostasis in the gut.Q37349789
Islet transplantation with alemtuzumab induction and calcineurin-free maintenance immunosuppression results in improved short- and long-term outcomesQ37381213
Activation of endothelial-leukocyte adhesion molecule 1 (ELAM-1) gene transcriptionQ37557587
State of the art of clinical islet transplantation and novel protocols of immunosuppressionQ37914760
Control of instant blood-mediated inflammatory reaction to improve islets of Langerhans engraftmentQ37942451
Free radicals in medicine. I. Chemical nature and biologic reactionsQ39192285
High-mobility group box 1 is involved in the initial events of early loss of transplanted islets in miceQ39251198
Xanthine oxidase: a critical mediator of myocardial injury during ischemia and reperfusion?Q39742543
Inhibition of MafA transcriptional activity and human insulin gene transcription by interleukin-1beta and mitogen-activated protein kinase kinase kinase in pancreatic islet beta cellsQ40116847
ERK1/2-dependent activation of transcription factors required for acute and chronic effects of glucose on the insulin gene promoterQ40421007
Central necrosis in isolated hypoxic human pancreatic islets: evidence for postisolation ischemiaQ40435647
Effect of brain death on gene expression and tissue activation in human donor kidneys.Q40476143
Inactivation of C5a anaphylatoxin by a peptide that is complementary to a region of C5a.Q40558699
Discovery of Gene Networks Regulating Cytokine-Induced Dysfunction and Apoptosis in Insulin-Producing INS-1 CellsQ40623131
Heme oxygenase-1 induction in islet cells results in protection from apoptosis and improved in vivo function after transplantationQ40783653
NF-kappa B and Rel: participants in a multiform transcriptional regulatory system.Q40884567
Adenovirus-mediated catalase gene transfer reduces oxidant stress in human, porcine and rat pancreatic isletsQ41006022
The bimodal effect of interleukin 1 on rat pancreatic beta-cells--stimulation followed by inhibition--depends upon dose, duration of exposure, and ambient glucose concentrationQ41374692
Pancreatic Islet Cell TransplantationQ41415689
Activation of human factor VII in the initiation of tissue factor-dependent coagulation.Q41446798
Suppression of p38 MAPK and JNK via Akt-mediated inhibition of apoptosis signal-regulating kinase 1 constitutes a core component of the beta-cell pro-survival effects of glucose-dependent insulinotropic polypeptideQ41766825
Diannexin decreases inflammatory cell infiltration into the islet graft, reduces β-cell apoptosis, and improves early graft functionQ42415943
Cloning and characterization of the 5'-transcriptional regulatory region of the human intercellular adhesion molecule 1 geneQ42464518
Attenuation of cross-talk between the complement and coagulation cascades by C5a blockade improves early outcomes after intraportal islet transplantationQ42768734
The sequential combination of a JNK inhibitor and simvastatin protects porcine islets from peritransplant apoptosis and inflammation.Q42774205
Immobilization of the soluble domain of human complement receptor 1 on agarose-encapsulated islets for the prevention of complement activationQ42925935
C5a-Inhibitory Peptide Combined with Gabexate Mesilate Prevents the Instant Blood-Mediated Inflammatory Reaction in a Rat Model of Islet TransplantationQ42943629
Islet Isolation From Human Pancreas With Extended Cold Ischemia TimeQ42943650
Dissecting the instant blood-mediated inflammatory reaction in islet xenotransplantationQ43239952
Positron emission tomography in clinical islet transplantationQ43257555
Bone marrow as an alternative site for islet transplantation.Q43272811
Increased plasma interleukin-6 in donors is associated with lower recipient hospital-free survival after cadaveric organ transplantationQ43639721
Serine-protease inhibition during islet isolation increases islet yield from human pancreases with prolonged ischemiaQ43729184
Exocrine contamination impairs implantation of pancreatic islets transplanted beneath the kidney capsuleQ43820105
Carbon monoxide protects pancreatic beta-cells from apoptosis and improves islet function/survival after transplantationQ43935412
Fresh islets are more effective for islet transplantation than cultured islets.Q43991450
Inhibition of thrombin abrogates the instant blood-mediated inflammatory reaction triggered by isolated human islets: possible application of the thrombin inhibitor melagatran in clinical islet transplantationQ44007209
Improvements in lung compliance after pulmonary transplantation: correlation with interleukin 8 expression.Q44403118
Regulation of ERK1 and ERK2 by glucose and peptide hormones in pancreatic beta cellsQ44463909
IL-1beta, IFN-gamma and TNF-alpha increase vulnerability of pancreatic beta cells to autoimmune destructionQ44468596
Nicotinamide inhibits tissue factor expression in isolated human pancreatic islets: implications for clinical islet transplantationQ44662213
Response of encapsulated rat pancreatic islets to hypoxiaQ44756098
Short-term storage of the ischemically damaged human pancreas by the two-layer method prior to islet isolationQ44811891
Role of CCL2/MCP-1 in islet transplantationQ45151585
Better vascular engraftment and function in pancreatic islets transplanted without prior cultureQ45254492
Single-donor, marginal-dose islet transplantation in patients with type 1 diabetesQ45267369
Life with oxygenQ45345070
Anakinra potentiates the protective effects of etanercept in transplantation of marginal mass human islets in immunodeficient miceQ45381912
Islet surface heparinization prevents the instant blood-mediated inflammatory reaction in islet transplantationQ45868552
Thrombin induces apoptosis in cultured neurons and astrocytes via a pathway requiring tyrosine kinase and RhoA activities.Q46007653
Hepatic IL-8 release during graft procurement is associated with impaired graft function after human liver transplantationQ46119682
Effect of short-term culture on functional and stress-related parameters in isolated human isletsQ46293013
Destruction of islet isografts by severe nonspecific inflammationQ46377623
P275copyright licenseCreative Commons Attribution 3.0 UnportedQ14947546
P6216copyright statuscopyrightedQ50423863
P304page(s)451035
P577publication date2014-04-30
P1433published inInternational journal of endocrinologyQ26842119
P1476titleInflammatory response in islet transplantation
P478volume2014

Reverse relations

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