Cold-inducible RNA-binding protein contributes to human antigen R and cyclin E1 deregulation in breast cancer

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Cold-inducible RNA-binding protein contributes to human antigen R and cyclin E1 deregulation in breast cancer is …
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scholarly articleQ13442814

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P356DOI10.1002/MC.20582
P932PMC publication ID2813375
P698PubMed publication ID19777567
P5875ResearchGate publication ID26834608

P2093author name stringRebecca S Hartley
Xun Guo
Yuehan Wu
P2860cites workThe UV-inducible RNA-binding protein A18 (A18 hnRNP) plays a protective role in the genotoxic stress responseQ24291731
Post-transcriptional regulation of thioredoxin by the stress inducible heterogenous ribonucleoprotein A18.Q24306489
A glycine-rich RNA-binding protein mediating cold-inducible suppression of mammalian cell growthQ24321515
Protein ligands mediate the CRM1-dependent export of HuR in response to heat shockQ24540046
HuR regulates p21 mRNA stabilization by UV lightQ24554331
RNA granulesQ24683783
Low-molecular-weight cyclin E: the missing link between biology and clinical outcomeQ24806316
Involvement of KSRP in the post-transcriptional regulation of human iNOS expression-complex interplay of KSRP with TTP and HuR.Q24816506
Differential expression and localization of the mRNA binding proteins, AU-rich element mRNA binding protein (AUF1) and Hu antigen R (HuR), in neoplastic lung tissueQ28141156
Relief of microRNA-mediated translational repression in human cells subjected to stressQ28246349
RNA-binding proteins: modular design for efficient functionQ28300258
The cold-inducible RNA-binding protein migrates from the nucleus to cytoplasmic stress granules by a methylation-dependent mechanism and acts as a translational repressorQ28506482
HuR and mRNA stabilityQ29615185
Cold-inducible RNA-binding protein bypasses replicative senescence in primary cells through extracellular signal-regulated kinase 1 and 2 activationQ33401471
HuR binding to cytoplasmic mRNA is perturbed by heat shockQ33895914
Expression of cold-inducible RNA-binding protein in the normal endometrium, endometrial hyperplasia, and endometrial carcinomaQ34207703
Oxygen-regulated expression of the RNA-binding proteins RBM3 and CIRP by a HIF-1-independent mechanismQ34312334
Cyclin E in normal and neoplastic cell cyclesQ34412356
Identification of several human homologs of hamster DNA damage-inducible transcripts. Cloning and characterization of a novel UV-inducible cDNA that codes for a putative RNA-binding protein.Q34442607
Cloning and characterization of human CIRP (cold-inducible RNA-binding protein) cDNA and chromosomal assignment of the geneQ34452765
Translational control of cytochrome c by RNA-binding proteins TIA-1 and HuRQ34563086
Expression of cyclin D1 and cyclin E in human gastric carcinoma and its clinicopathologic significanceQ34656308
Cyclin E and its low molecular weight forms in human cancer and as targets for cancer therapy.Q35542762
Redundant cyclin overexpression and gene amplification in breast cancer cellsQ36090819
Cyclin E as a prognostic and predictive marker in breast cancerQ36206979
HuR, an RNA-binding protein, involved in the control of cellular differentiation.Q36376209
Stress-induced reversal of microRNA repression and mRNA P-body localization in human cells.Q36768209
Persistent redistribution of poly-adenylated mRNAs correlates with translation arrest and cell death following global brain ischemia and reperfusionQ36807293
Translation regulatory factor RBM3 is a proto-oncogene that prevents mitotic catastropheQ37180861
HuR contributes to cyclin E1 deregulation in MCF-7 breast cancer cellsQ38310628
Cold-inducible RNA binding protein is required for the expression of adhesion molecules and embryonic cell movement in Xenopus laevisQ38314423
Overexpression of the embryonic-lethal abnormal vision-like protein HuR in ovarian carcinoma is a prognostic factor and is associated with increased cyclooxygenase 2 expressionQ38345875
Role of the RNA-binding protein HuR in colon carcinogenesisQ38349167
Detection of low molecular weight derivatives of cyclin E1 is a function of cyclin E1 protein levels in breast cancer.Q40253957
Tumor-specific low molecular weight forms of cyclin E induce genomic instability and resistance to p21, p27, and antiestrogens in breast cancerQ40559137
HuR regulates cyclin A and cyclin B1 mRNA stability during cell proliferationQ40749123
Processing of cyclin E differs between normal and tumor breast cellsQ40900933
The RNA-binding protein HuR promotes cell migration and cell invasion by stabilizing the beta-actin mRNA in a U-rich-element-dependent mannerQ41977826
Cirp protects against tumor necrosis factor-alpha-induced apoptosis via activation of extracellular signal-regulated kinaseQ42803898
ELAV protein HuA (HuR) can redistribute between nucleus and cytoplasm and is upregulated during serum stimulation and T cell activation.Q42825905
Xenopus cold-inducible RNA-binding protein 2 interacts with ElrA, the Xenopus homolog of HuR, and inhibits deadenylation of specific mRNAs.Q44588566
Diurnal change of the cold-inducible RNA-binding protein (Cirp) expression in mouse brainQ48478517
Cytoplasmic HuR expression is a prognostic factor in invasive ductal breast carcinoma.Q53359627
Cyclin E, a potential prognostic marker for breast cancerQ72662855
Expression of cell-cycle regulators p27Kip1 and cyclin E, alone and in combination, correlate with survival in young breast cancer patientsQ73034313
Implication of malignancy and prognosis of p27(kip1), Cyclin E, and Cdk2 expression in epithelial ovarian tumorsQ74590448
Activation of cyclin E-dependent kinase activity in colorectal cancerQ77073467
Expression of the ELAV-like protein HuR is associated with higher tumor grade and increased cyclooxygenase-2 expression in human breast carcinomaQ80489785
P433issue2
P921main subjectRNA-binding proteinsQ3928341
P304page(s)130-140
P577publication date2010-02-01
P1433published inMolecular CarcinogenesisQ15724597
P1476titleCold-inducible RNA-binding protein contributes to human antigen R and cyclin E1 deregulation in breast cancer
P478volume49

Reverse relations

cites work (P2860)
Q36962542Cold inducible RNA binding protein upregulation in pituitary corticotroph adenoma induces corticotroph cell proliferation via Erk signaling pathway
Q50096603Cold-inducible RNA binding protein in cancer and inflammation
Q50089799Cold-inducible RNA-binding protein (CIRP) induces translation of the cell-cycle inhibitor p27Kip1.
Q36532681Cold-inducible RNA-binding protein CIRP/hnRNP A18 regulates telomerase activity in a temperature-dependent manner
Q28079941Cold-inducible proteins CIRP and RBM3, a unique couple with activities far beyond the cold
Q28075325Current Evidence and Future Perspectives on HuR and Breast Cancer Development, Prognosis, and Treatment
Q51054802Cytoplasmic HuR expression correlates with P-gp, HER-2 positivity, and poor outcome in breast cancer.
Q35229441Environmental stress induces trinucleotide repeat mutagenesis in human cells
Q55180524Expression of cold-inducible RNA-binding protein (CIRP) in renal cell carcinoma and the effect of CIRP downregulation cell proliferation and chemosensitivity to gemcitabine.
Q89574388Extracellular CIRP induces macrophage endotoxin tolerance through IL-6R-mediated STAT3 activation
Q26744134Hallmarks of cancer and AU-rich elements
Q92626753Loss of Cirbp expression is correlated with the malignant progression and poor prognosis in nasopharyngeal carcinoma
Q21559691NF-κB-dependent role for cold-inducible RNA binding protein in regulating interleukin 1β
Q28248667Posttranscriptional regulation of cancer traits by HuR
Q44780842Protein overexpression of CIRP and TLR4 in oral squamous cell carcinoma: an immunohistochemical and clinical correlation analysis
Q26748745RNA-binding proteins in eye development and disease: implication of conserved RNA granule components
Q46262130Recent progress in the research of cold-inducible RNA-binding protein
Q64996748The MAPK Pathway-Based Drug Therapeutic Targets in Pituitary Adenomas.
Q89451776The Mechanism of CIRP in Regulation of STAT3 Phosphorylation and Bag-1/S Expression Upon UVB Radiation
Q36792659Three-dimensional collagen represses cyclin E1 via β1 integrin in invasive breast cancer cells
Q55508834V-ATPase-dependent repression of androgen receptor in prostate cancer cells.

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