| scholarly article | Q13442814 |
| P2093 | author name string | Jeffrey S Rubin | |
| Robert Callahan | |||
| Ten-Yang Yen | |||
| Malgorzata Klauzinska | |||
| Yoshimi Endo | |||
| Bolormaa Baljinnyam | |||
| Sheng-Jian Li | |||
| Bruce Macher | |||
| P2860 | cites work | RSPO4 is the major gene in autosomal-recessive anonychia and mutations cluster in the furin-like cysteine-rich domains of the Wnt signaling ligand R-spondin 4. | Q34698254 |
| Wnt-3a and Dickkopf-1 stimulate neurite outgrowth in Ewing tumor cells via a Frizzled3- and c-Jun N-terminal kinase-dependent mechanism | Q36498025 | ||
| R-Spondin family members regulate the Wnt pathway by a common mechanism | Q36678039 | ||
| R-spondin1--discovery of the long-missing, mammalian female-determining gene? | Q36764828 | ||
| Wnt/beta-catenin signaling: new (and old) players and new insights | Q37109729 | ||
| Mouse R-spondin2 is required for apical ectodermal ridge maintenance in the hindlimb | Q37216344 | ||
| DKK1 antagonizes Wnt signaling without promotion of LRP6 internalization and degradation | Q39978358 | ||
| R-spondin1 synergizes with Wnt3A in inducing osteoblast differentiation and osteoprotegerin expression | Q40017828 | ||
| Initiation of Wnt signaling: control of Wnt coreceptor Lrp6 phosphorylation/activation via frizzled, dishevelled and axin functions. | Q40036004 | ||
| Analysis of endogenous LRP6 function reveals a novel feedback mechanism by which Wnt negatively regulates its receptor | Q40094304 | ||
| MMTV insertional mutagenesis identifies genes, gene families and pathways involved in mammary cancer. | Q40139233 | ||
| R-spondin1, a novel intestinotrophic mitogen, ameliorates experimental colitis in mice. | Q43409960 | ||
| R-spondin1 is a high affinity ligand for LRP6 and induces LRP6 phosphorylation and beta-catenin signaling | Q50336904 | ||
| Syndromic true hermaphroditism due to an R-spondin1 (RSPO1) homozygous mutation. | Q50454068 | ||
| Dynamic expression of R-spondin family genes in mouse development | Q52004865 | ||
| R-spondin1 tips the balance in sex determination | Q55671190 | ||
| R-spondin2 expression in the apical ectodermal ridge is essential for outgrowth and patterning in mouse limb development | Q80166382 | ||
| Novel mechanism of Wnt signalling inhibition mediated by Dickkopf-1 interaction with LRP6/Arrow | Q24291392 | ||
| Head inducer Dickkopf-1 is a ligand for Wnt coreceptor LRP6 | Q24291433 | ||
| R-Spondin1 regulates Wnt signaling by inhibiting internalization of LRP6 | Q24292884 | ||
| Mouse cristin/R-spondin family proteins are novel ligands for the Frizzled 8 and LRP6 receptors and activate beta-catenin-dependent gene expression | Q24308067 | ||
| Wnt induces LRP6 signalosomes and promotes dishevelled-dependent LRP6 phosphorylation | Q24310980 | ||
| Vascular development in the retina and inner ear: control by Norrin and Frizzled-4, a high-affinity ligand-receptor pair | Q24318751 | ||
| Crystal structure of the TSP-1 type 1 repeats | Q27639866 | ||
| Wnt/beta-catenin signaling in development and disease | Q27860784 | ||
| The Wnt signaling pathway in development and disease | Q27861019 | ||
| LDL-receptor-related protein 6 is a receptor for Dickkopf proteins | Q28116567 | ||
| Mutations in R-spondin 4 (RSPO4) underlie inherited anonychia | Q28118698 | ||
| Kremen proteins are Dickkopf receptors that regulate Wnt/beta-catenin signalling | Q28202812 | ||
| Casein kinase 1 gamma couples Wnt receptor activation to cytoplasmic signal transduction | Q28286117 | ||
| R-spondin3 is required for mouse placental development | Q28512828 | ||
| R-spondin, a novel gene with thrombospondin type 1 domain, was expressed in the dorsal neural tube and affected in Wnts mutants | Q28589493 | ||
| R-spondin 2 is required for normal laryngeal-tracheal, lung and limb morphogenesis | Q28590027 | ||
| Targeted disruption of the Wnt regulator Kremen induces limb defects and high bone density | Q28975610 | ||
| A dual-kinase mechanism for Wnt co-receptor phosphorylation and activation | Q29618700 | ||
| Determination of glycosylation sites and disulfide bond structures using LC/ESI-MS/MS analysis. | Q30358167 | ||
| Cloning and identification of a cDNA that encodes a novel human protein with thrombospondin type I repeat domain, hPWTSR. | Q30872613 | ||
| A new common integration site, Int7, for the mouse mammary tumor virus in mouse mammary tumors identifies a gene whose product has furin-like and thrombospondin-like sequences | Q33908673 | ||
| R-Spondin proteins: a novel link to beta-catenin activation | Q33992278 | ||
| R-Spondin2 is a secreted activator of Wnt/beta-catenin signaling and is required for Xenopus myogenesis | Q34356591 | ||
| Mitogenic influence of human R-spondin1 on the intestinal epithelium | Q34444196 | ||
| R-spondin1 is essential in sex determination, skin differentiation and malignancy. | Q34573938 | ||
| The gene encoding R-spondin 4 (RSPO4), a secreted protein implicated in Wnt signaling, is mutated in inherited anonychia | Q34573951 | ||
| Mutations in the gene encoding the Wnt-signaling component R-spondin 4 (RSPO4) cause autosomal recessive anonychia | Q34594194 | ||
| P433 | issue | 6 | |
| P1104 | number of pages | 10 | |
| P304 | page(s) | 916-925 | |
| P577 | publication date | 2009-06-01 | |
| P1433 | published in | Cellular Signalling | Q1524097 |
| P1476 | title | Loss-of-function point mutations and two-furin domain derivatives provide insights about R-spondin2 structure and function | |
| P478 | volume | 21 |
| Q26991478 | Adult mammalian stem cells: the role of Wnt, Lgr5 and R-spondins |
| Q27023891 | Cellular signaling and biological functions of R-spondins |
| Q34233989 | Computational biophysical, biochemical, and evolutionary signature of human R-spondin family proteins, the member of canonical Wnt/β-catenin signaling pathway |
| Q26747432 | Control of Wnt Receptor Turnover by R-spondin-ZNRF3/RNF43 Signaling Module and Its Dysregulation in Cancer |
| Q27679218 | Crystal Structures of Lgr4 and Its Complex with R-Spondin1 |
| Q30399043 | Intrinsic disorder in spondins and some of their interacting partners |
| Q92778325 | Production, purification and characterization of recombinant human R-spondin1 (RSPO1) protein stably expressed in human HEK293 cells |
| Q64099227 | R-spondin signaling as a pivotal regulator of tissue development and homeostasis |
| Q59065150 | RSPO2 inhibition of RNF43 and ZNRF3 governs limb development independently of LGR4/5/6 |
| Q28478701 | Recombinant R-spondin2 and Wnt3a Up- and Down-Regulate Novel Target Genes in C57MG Mouse Mammary Epithelial Cells |
| Q37546875 | Regulation of the follistatin gene by RSPO-LGR4 signaling via activation of the WNT/β-catenin pathway in skeletal myogenesis |
| Q39512092 | Rspo2/Int7 regulates invasiveness and tumorigenic properties of mammary epithelial cells. |
| Q27680600 | Structural and molecular basis of ZNRF3/RNF43 transmembrane ubiquitin ligase inhibition by the Wnt agonist R-spondin |
| Q58745021 | Tales from the crypt: intestinal niche signals in tissue renewal, plasticity and cancer |
| Q36392765 | The R-spondin family of proteins: emerging regulators of WNT signaling |
| Q27021525 | The R-spondin protein family |
| Q34159158 | The canonical Wnt signaling activator, R-spondin2, regulates craniofacial patterning and morphogenesis within the branchial arch through ectodermal–mesenchymal interaction |
| Q27678577 | The structural basis of R-spondin recognition by LGR5 and RNF43 |
| Q90675233 | Wnt/β-Catenin Signaling and Obesity |
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