Regulation of the mitochondrial permeability transition pore by the outer membrane does not involve the peripheral benzodiazepine receptor (Translocator Protein of 18 kDa (TSPO)).

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Regulation of the mitochondrial permeability transition pore by the outer membrane does not involve the peripheral benzodiazepine receptor (Translocator Protein of 18 kDa (TSPO)). is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M114.549634
P932PMC publication ID4022851
P698PubMed publication ID24692541
P5875ResearchGate publication ID261294679

P50authorPaolo BernardiQ16199016
Fernanda RicchelliQ115923577
Fabio Di LisaQ43050673
Justina SileikyteQ63992683
P2093author name stringRoberta Menabò
Michael Forte
Andrea Carpi
Elizabeth Blachly-Dyson
Randall Sewell
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Cyclophilin D controls mitochondrial pore-dependent Ca(2+) exchange, metabolic flexibility, and propensity for heart failure in miceQ24598637
Peripheral benzodiazepine receptor ligand, PK11195 induces mitochondria cytochrome c release and dissipation of mitochondria potential via induction of mitochondria permeability transitionQ79754296
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The ADP/ATP translocator is not essential for the mitochondrial permeability transition poreQ28241418
Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell deathQ28242641
Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell deathQ28242653
Dimers of mitochondrial ATP synthase form the permeability transition poreQ28287824
Voltage-dependent anion channels are dispensable for mitochondrial-dependent cell deathQ28297152
Regulation of the inner membrane mitochondrial permeability transition by the outer membrane translocator protein (peripheral benzodiazepine receptor)Q28297948
Translocator protein/peripheral benzodiazepine receptor is not required for steroid hormone biosynthesisQ28301125
2-Aryl-3-indoleacetamides (FGIN-1): a new class of potent and specific ligands for the mitochondrial DBI receptor (MDR)Q28326791
High throughput microplate respiratory measurements using minimal quantities of isolated mitochondriaQ28479257
Recombinant expression of the voltage-dependent anion channel enhances the transfer of Ca2+ microdomains to mitochondriaQ28565012
Targeted disruption of the peripheral-type benzodiazepine receptor gene inhibits steroidogenesis in the R2C Leydig tumor cell lineQ28571640
The peripheral-type benzodiazepine receptor is involved in control of Ca2+-induced permeability transition pore opening in rat brain mitochondriaQ28572594
Cyclophilin D is a component of mitochondrial permeability transition and mediates neuronal cell death after focal cerebral ischemiaQ28585666
Translocator protein 2 is involved in cholesterol redistribution during erythropoiesisQ28589759
A distinct pathway remodels mitochondrial cristae and mobilizes cytochrome c during apoptosisQ29620536
Macromolecular organization of ATP synthase and complex I in whole mitochondria.Q30503729
Fluctuations in mitochondrial membrane potential caused by repetitive gating of the permeability transition poreQ30785418
Opening of the mitochondrial permeability transition pore causes depletion of mitochondrial and cytosolic NAD+ and is a causative event in the death of myocytes in postischemic reperfusion of the heart.Q31552541
The mitochondrial permeability transition, release of cytochrome c and cell death. Correlation with the duration of pore openings in situQ31779663
Properties of the permeability transition in VDAC1(-/-) mitochondriaQ33240486
NMR studies of an immunomodulatory benzodiazepine binding to its molecular target on the mitochondrial F(1)F(0)-ATPaseQ33505368
The ATP synthase is involved in generating mitochondrial cristae morphologyQ34085619
The mitochondrion in apoptosis: how Pandora's box opensQ34286386
Properties of the permeability transition pore in mitochondria devoid of Cyclophilin D.Q34406704
Porphyrins are endogenous ligands for the mitochondrial (peripheral-type) benzodiazepine receptorQ34612661
The simplest statistical test: how to check for a difference between treatmentsQ34647269
Activation of the mitochondrial permeability transition pore modulates Ca2+ responses to physiological stimuli in adult neuronsQ35245867
Mitochondrial permeability transitions: how many doors to the house?Q35994123
Mitochondrial benzodiazepine receptor linked to inner membrane ion channels by nanomolar actions of ligandsQ36104257
An investigation of mitochondrial inner membranes by rapid-freeze deep-etch techniquesQ36220864
The mitochondrial permeability transition from in vitro artifact to disease targetQ36464595
The role of transporters in cellular heme and porphyrin homeostasisQ36763207
Singlet oxygen produced by photodynamic action causes inactivation of the mitochondrial permeability transition poreQ36878388
Superoxide flashes in single mitochondriaQ36900957
Shedding light on the mitochondrial permeability transition.Q37850094
Roles of mitochondrial benzodiazepine receptor in the heartQ37860663
Mechanisms by which mitochondria transport calciumQ37920440
Structural and functional evolution of the translocator protein (18 kDa).Q37987954
The permeability transition pore as a Ca(2+) release channel: new answers to an old questionQ38003544
Role of mitochondria in steroidogenesisQ38061274
The mitochondrial permeability transition pore: a mystery solved?Q38106976
Crucial role of sulfhydryl groups in the mitochondrial inner membrane structureQ38352354
Relationship between configuration, function, and permeability in calcium-treated mitochondriaQ39780520
Transient and long-lasting openings of the mitochondrial permeability transition pore can be monitored directly in intact cells by changes in mitochondrial calcein fluorescenceQ40137371
Inhibition of the mitochondrial F1F0-ATPase by ligands of the peripheral benzodiazepine receptorQ40179515
Peripheral benzodiazepine receptor agonists exhibit potent antiapoptotic activitiesQ40918233
Dimer ribbons of ATP synthase shape the inner mitochondrial membraneQ41623192
VDAC-dependent permeabilization of the outer mitochondrial membrane by superoxide induces rapid and massive cytochrome c releaseQ41764200
Mitochondrial non-specific pores remain closed during cardiac ischaemia, but open upon reperfusionQ41977320
Mitochondrial channel activity studied by patch-clamping mitoplastsQ42014495
Ca 2+ -dependent autophagy is enhanced by the pharmacological agent PK11195.Q43079159
Peripheral-type benzodiazepine receptor ligands: mitochondrial permeability transition induction in rat cardiac tissue.Q43552483
The effects of singlet oxygen produced by photodynamic action on the mitochondrial permeability transition differ in accordance with the localization of the sensitizerQ43614231
Temporally regulated and tissue-specific gene manipulations in the adult and embryonic heart using a tamoxifen-inducible Cre proteinQ43664631
Toxicity of alpidem, a peripheral benzodiazepine receptor ligand, but not zolpidem, in rat hepatocytes: role of mitochondrial permeability transition and metabolic activation.Q43768065
Platelet-activating factor induces permeability transition and cytochrome c release in isolated brain mitochondriaQ44059814
PK11195 inhibits mitophagy targeting the F1Fo-ATPsynthase in Bcl-2 knock-down cellsQ44154406
Phenylarsine oxide induces the cyclosporin A-sensitive membrane permeability transition in rat liver mitochondriaQ44286753
Mitochondrial benzodiazepine receptors mediate inhibition of mitochondrial respiratory controlQ44519611
The inner mitochondrial membrane contains ion-conducting channels similar to those found in bacteria.Q44810762
The giant channel of the inner mitochondrial membrane is inhibited by cyclosporin A.Q45215970
Effect of cyclosporine on reperfusion injury in acute myocardial infarctionQ46453592
Steroid hormone synthesis in mitochondriaQ46623699
The peripheral-type benzodiazepine receptor. Localization to the mitochondrial outer membraneQ50336006
Protoporphyrin IX, an endogenous ligand of the peripheral benzodiazepine receptor, potentiates induction of the mitochondrial permeability transition and the killing of cultured hepatocytes by rotenone.Q51617380
Switch from inhibition to activation of the mitochondrial permeability transition during hematoporphyrin-mediated photooxidative stress. Unmasking pore-regulating external thiols.Q51736462
Differentiation between two ligands for peripheral benzodiazepine binding sites, [3H]R05-4864 and [3H]PK 11195, by thermodynamic studiesQ51852591
Mitochondria Are Excitable Organelles Capable of Generating and Conveying Electrical and Calcium SignalsQ53967833
Evidence for complex binding profiles and species differences at the translocator protein (TSPO) (18 kDa).Q55462261
Lonidamine triggers apoptosis via a direct, Bcl-2-inhibited effect on the mitochondrial permeability transition poreQ57082833
Prevention of the oxygen paradox in hypoxic-reoxygenated heartsQ67954418
Characterization of porphyrin interactions with peripheral type benzodiazepine receptorsQ69844746
Control of the mitochondrial inner membrane permeability by sulfhydryl groupsQ70445279
Site-directed mutagenesis of the peripheral benzodiazepine receptor: identification of amino acids implicated in the binding site of Ro5-4864Q72377395
Peripheral-type benzodiazepine receptor function in cholesterol transport. Identification of a putative cholesterol recognition/interaction amino acid sequence and consensus patternQ77614441
P433issue20
P407language of work or nameEnglishQ1860
P304page(s)13769-13781
P577publication date2014-04-01
P1433published inJournal of Biological ChemistryQ867727
P1476titleRegulation of the mitochondrial permeability transition pore by the outer membrane does not involve the peripheral benzodiazepine receptor (Translocator Protein of 18 kDa (TSPO))
P478volume289

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