Identification of pel, a Streptococcus pyogenes locus that affects both surface and secreted proteins

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Identification of pel, a Streptococcus pyogenes locus that affects both surface and secreted proteins is …
instance of (P31):
scholarly articleQ13442814

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P932PMC publication ID103629
P698PubMed publication ID10498714

P2093author name stringZ Li
A Podbielski
B Kreikemeyer
M D Boyle
D D Sledjeski
P2860cites workHyaluronic acid capsule is a virulence factor for mucoid group A streptococciQ24561897
A small RNA acts as an antisilencer of the H-NS-silenced rcsA gene of Escherichia coliQ24563821
Synthesis of staphylococcal virulence factors is controlled by a regulatory RNA moleculeQ24564360
Detection of specific sequences among DNA fragments separated by gel electrophoresisQ25939003
Association of phenotypic and genotypic characteristics of invasive Streptococcus pyogenes isolates with clinical components of streptococcal toxic shock syndromeQ33605090
Protein F, a fibronectin-binding protein, is an adhesin of the group A streptococcus Streptococcus pyogenesQ33613212
Molecular analysis of the capsule gene region of group A Streptococcus: the hasAB genes are sufficient for capsule expressionQ33737149
Reduced virulence of group A streptococcal Tn916 mutants that do not produce streptolysin SQ33752582
A role for trigger factor and an rgg-like regulator in the transcription, secretion and processing of the cysteine proteinase of Streptococcus pyogenesQ33889824
A response regulator that represses transcription of several virulence operons in the group A streptococcusQ33992290
Streptococcal infections of skin and soft tissuesQ34368541
Identification of a gene that regulates expression of M protein, the major virulence determinant of group A streptococciQ34373919
PCR amplification of up to 35-kb DNA with high fidelity and high yield from lambda bacteriophage templatesQ35100239
An extracellular factor regulating expression of the chromosomal aminoglycoside 2'-N-acetyltransferase of Providencia stuartiiQ35137673
The group A streptococcal virR49 gene controls expression of four structural vir regulon genesQ35377101
Temporal production of streptococcal erythrogenic toxin B (streptococcal cysteine proteinase) in response to nutrient depletionQ35547623
Insertional mutagenesis and recovery of interrupted genes of Streptococcus mutans by using transposon Tn917: preliminary characterization of mutants displaying acid sensitivity and nutritional requirementsQ35609637
Insertional inactivation of Streptococcus pyogenes sod suggests that prtF is regulated in response to a superoxide signalQ35610655
Physical and genetic chromosomal map of an M type 1 strain of Streptococcus pyogenesQ35613533
Role of mga in growth phase regulation of virulence genes of the group A streptococcusQ35628204
A rapid and convenient method for the preparation and storage of competent bacterial cellsQ36001361
Mry, a trans-acting positive regulator of the M protein gene of Streptococcus pyogenes with similarity to the receptor proteins of two-component regulatory systemsQ36144820
Coregulation of type 12 M protein and streptococcal C5a peptidase genes in group A streptococci: evidence for a virulence regulon controlled by the virR locusQ36157887
Complete nucleotide sequence of macrolide-lincosamide-streptogramin B-resistance transposon Tn917 in Streptococcus faecalisQ36279329
Insertional inactivation of streptolysin S expression in Streptococcus pyogenesQ36332336
Genetic manipulation of pathogenic streptococciQ36439609
Molecular characterization of group A streptococcal (GAS) oligopeptide permease (opp) and its effect on cysteine protease productionQ36828672
Expression of M type 12 protein by a group A streptococcus exhibits phaselike variation: evidence for coregulation of colony opacity determinants and M proteinQ37024048
Regulation of the pAD1 sex pheromone response of Enterococcus faecalis by direct interaction between the cAD1 peptide mating signal and the negatively regulating, DNA-binding TraA proteinQ37420850
Identification of key gene products required for acquisition of plasmin-like enzymatic activity by group A streptococciQ38346528
Use of the lactococcal nisA promoter to regulate gene expression in gram-positive bacteria: comparison of induction level and promoter strength.Q39563595
Production of stabilized virulence factor-negative variants by group A streptococci during stationary phase.Q39572415
Controlled gene expression systems for lactic acid bacteria: transferable nisin-inducible expression cassettes for Lactococcus, Leuconostoc, and Lactobacillus spp.Q39803517
Distinct profiles of immunoglobulin G-binding-protein expression by invasive serotype M1 isolates of Streptococcus pyogenesQ39809814
Regulation of virulence by environmental signals in group A streptococci: influence of osmolarity, temperature, gas exchange, and iron limitation on emm transcriptionQ39823542
Environmental regulation of virulence in group A streptococci: transcription of the gene encoding M protein is stimulated by carbon dioxideQ39936355
M protein and protein F act as important determinants of cell-specific tropism of Streptococcus pyogenes in skin tissueQ40340242
Severe invasive group A streptococcal disease: clinical description and mechanisms of pathogenesisQ40964384
Electrotransformation of Streptococcus pyogenes with plasmid and linear DNA.Q41145871
Streptococcal competence for genetic transformation: regulation by peptide pheromonesQ41435667
Quorum sensing by peptide pheromones and two-component signal-transduction systems in Gram-positive bacteriaQ41529090
Pheromone-induced production of antimicrobial peptides in LactobacillusQ42447553
Characterization of nra, a global negative regulator gene in group A streptococciQ42595830
The identification of rofA, a positive-acting regulatory component of prtF expression: use of an m gamma delta-based shuttle mutagenesis strategy in Streptococcus pyogenesQ42606655
What is the size of the group A streptococcal vir regulon? The Mga regulator affects expression of secreted and surface virulence factorsQ42648623
Molecular epidemiology of group A streptococcus M type 1 infectionsQ44175485
The group A streptococcal dipeptide permease (Dpp) is involved in the uptake of essential amino acids and affects the expression of cysteine proteaseQ47782491
Characterization of a two-component system in Streptococcus pyogenes which is involved in regulation of hyaluronic acid productionQ47988355
Identification of csrR/csrS, a genetic locus that regulates hyaluronic acid capsule synthesis in group A StreptococcusQ48014401
A small, stable RNA induced by oxidative stress: role as a pleiotropic regulator and antimutatorQ48047346
Bacterial interference caused by autoinducing peptide variantsQ48048389
Enzymatic iodination of polypeptides with 125I to high specific activityQ49184249
Surface protein-CAT reporter fusions demonstrate differential gene expression in the vir regulon of Streptococcus pyogenesQ54265347
Regulation of exoprotein gene expression in Staphylococcus aureus by agar.Q54438418
Genetic and phenotypic diversity among isolates of Streptococcus pyogenes from invasive infectionsQ71007492
Insertional inactivation of virR in Streptococcus pyogenes M49 demonstrates that VirR functions as a positive regulator of ScpA, FcRA, OF, and M proteinQ72221878
Cysteine endopeptidases of parasitic protozoaQ72519401
Adherence and fibronectin binding are environmentally regulated in the group A streptococciQ72738487
Insertional inactivation of streptolysin S expression is associated with altered riboflavin metabolism in Streptococcus pyogenesQ73318821
Pheromone-inducible expression of an aggregation protein in Enterococcus faecalis requires interaction of a plasmid-encoded RNA with components of the ribosomeQ73356103
Role of emm and mrp genes in the virulence of group A streptococcal isolate 64/14 in a mouse model of skin infectionQ74422408
Kinase-phosphatase competition regulates Bacillus subtilis developmentQ77432414
P433issue19
P407language of work or nameEnglishQ1860
P921main subjectStreptococcus pyogenesQ131271
P1104number of pages9
P304page(s)6019-6027
P577publication date1999-10-01
P1433published inJournal of BacteriologyQ478419
P1476titleIdentification of pel, a Streptococcus pyogenes locus that affects both surface and secreted proteins
P478volume181

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cites work (P2860)
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Q33557725CcpA and LacD.1 affect temporal regulation of Streptococcus pyogenes virulence genes
Q36804317CcpA-mediated repression of streptolysin S expression and virulence in the group A streptococcus.
Q35106098Combined contributions of streptolysin O and streptolysin S to virulence of serotype M5 Streptococcus pyogenes strain Manfredo
Q34160197Comparative genome-wide analysis of small RNAs of major Gram-positive pathogens: from identification to application
Q33768828Effects of oligopeptide permease in group a streptococcal infection
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Q35133183Extracellular enzymes with immunomodulating activities: variations on a theme in Streptococcus pyogenes
Q39529596Generation and surface localization of intact M protein in Streptococcus pyogenes are dependent on sagA.
Q33598605Genetic locus for streptolysin S production by group A streptococcus
Q39110664Identification and characterization of bicistronic speB and prsA gene expression in the group A Streptococcus
Q30658605Identification of Rgg-regulated exoproteins of Streptococcus pyogenes
Q31109211Identification of a streptolysin S-associated gene cluster and its role in the pathogenesis of Streptococcus iniae disease
Q24595810Identification of small RNAs in Francisella tularensis
Q33769440Impact of the SpeB protease on binding of the complement regulatory proteins factor H and factor H-like protein 1 by Streptococcus pyogenes
Q34120910Influence of recombination and niche separation on the population genetic structure of the pathogen Streptococcus pyogenes
Q34005015Inverse relation between disease severity and expression of the streptococcal cysteine protease, SpeB, among clonal M1T1 isolates recovered from invasive group A streptococcal infection cases
Q24797800Mouse skin passage of a Streptococcus pyogenes Tn917 mutant of sagA/pel restores virulence, beta-hemolysis and sagA/pel expression without altering the position or sequence of the transposon
Q34350583Novel regulatory small RNAs in Streptococcus pyogenes
Q34008621Reciprocal, temporal expression of SpeA and SpeB by invasive M1T1 group a streptococcal isolates in vivo
Q34006146Restoration of Mga function to a Streptococcus pyogenes strain (M Type 50) that is virulent in mice
Q34118071Rgg influences the expression of multiple regulatory loci to coregulate virulence factor expression in Streptococcus pyogenes
Q41770404Role for sagA and siaA in quorum sensing and iron regulation in Streptococcus pyogenes
Q33749178Streptolysin S Contributes to Group A Streptococcal Translocation across an Epithelial Barrier
Q37592194Streptolysin S-like virulence factors: the continuing sagA.
Q33793995The M protein is dispensable for maturation of streptococcal cysteine protease SpeB.
Q41930343The Regulatory Small RNA MarS Supports Virulence of Streptococcus pyogenes.
Q24624170The group A Streptococcus small regulatory RNA FasX enhances streptokinase activity by increasing the stability of the ska mRNA transcript
Q40488735The majority of 9,729 group A streptococcus strains causing disease secrete SpeB cysteine protease: pathogenesis implications.
Q37586990The sagA/pel locus does not regulate the expression of the M protein of the M1T1 lineage of group A Streptococcus
Q43127899vfr, a novel locus affecting cysteine protease production in Streptococcus pyogenes

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