| P2093 | author name string | Jack A Roth | |
| | Lin Ji | |
| | Gitanjali Jayachandran | |
| | Bingbing Wang | |
| | Kentaro Ueda | |
| P2860 | cites work | High resolution chromosome 3p allelotyping of human lung cancer and preneoplastic/preinvasive bronchial epithelium reveals multiple, discontinuous sites of 3p allele loss and three regions of frequent breakpoints | Q73679061 |
| | Cellular and molecular determinants of cisplatin resistance | Q77809152 |
| | DNA damage tumor suppressor genes and genomic instability | Q35755997 |
| | Computerized polymorphic marker identification: experimental validation and a predicted human polymorphism catalog | Q36494289 |
| | H2AX haploinsufficiency modifies genomic stability and tumor susceptibility | Q36533572 |
| | Activation of programmed cell death by anticancer agents: cisplatin as a model system | Q37974752 |
| | Chk2 activation and phosphorylation-dependent oligomerization | Q39674829 |
| | Requirement for caspase-2 in stress-induced apoptosis before mitochondrial permeabilization | Q40708852 |
| | The DNA damage-dependent intra-S phase checkpoint is regulated by parallel pathways | Q40750310 |
| | Induction of apoptosis in cisplatin-sensitive and -resistant human ovarian cancer cell lines | Q41086518 |
| | Activation of programmed cell death (apoptosis) by cisplatin, other anticancer drugs, toxins and hyperthermia | Q41714603 |
| | Hyperphosphorylation of histone H2A.X and dephosphorylation of histone H1 subtypes in the course of apoptosis | Q42819537 |
| | Caspase-2 acts upstream of mitochondria to promote cytochrome c release during etoposide-induced apoptosis | Q44028668 |
| | Ataxia-telangiectasia-mutated (ATM) and NBS1-dependent phosphorylation of Chk1 on Ser-317 in response to ionizing radiation | Q44317026 |
| | Platinum-DNA adduct, nucleotide excision repair and platinum based anti-cancer chemotherapy. | Q54111946 |
| | Differential sensitivity to the induction of apoptosis by cisplatin in proliferating and quiescent immature rat thymocytes is independent of the levels of drug accumulation and DNA adduct formation. | Q54211342 |
| | Induction of apoptosis and inhibition of tumorigenicity and tumor growth by adenovirus vector-mediated fragile histidine triad (FHIT) gene overexpression | Q64381393 |
| | Analysis of events associated with cell cycle arrest at G2 phase and cell death induced by cisplatin | Q64390050 |
| | Linkage of ATM to cell cycle regulation by the Chk2 protein kinase | Q22008502 |
| | The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis | Q24291114 |
| | SMC1 is a downstream effector in the ATM/NBS1 branch of the human S-phase checkpoint | Q24292395 |
| | MDC1 is a mediator of the mammalian DNA damage checkpoint | Q24296229 |
| | ATR-mediated checkpoint pathways regulate phosphorylation and activation of human Chk1 | Q24550952 |
| | Expression of several genes in the human chromosome 3p21.3 homozygous deletion region by an adenovirus vector results in tumor suppressor activities in vitro and in vivo | Q24625463 |
| | A human Cds1-related kinase that functions downstream of ATM protein in the cellular response to DNA damage | Q24651421 |
| | Ataxia telangiectasia-mutated phosphorylates Chk2 in vivo and in vitro | Q24656275 |
| | Essential and dispensable roles of ATR in cell cycle arrest and genome maintenance | Q24672646 |
| | Anticancer drug resistance induced by disruption of the Saccharomyces cerevisiae NPR2 gene: a novel component involved in cisplatin- and doxorubicin-provoked cell kill | Q27936439 |
| | The DNA damage response: putting checkpoints in perspective | Q28131713 |
| | The 630-kb lung cancer homozygous deletion region on human chromosome 3p21.3: identification and evaluation of the resident candidate tumor suppressor genes. The International Lung Cancer Chromosome 3p21.3 Tumor Suppressor Gene Consortium | Q28138149 |
| | Initiation of DNA fragmentation during apoptosis induces phosphorylation of H2AX histone at serine 139 | Q28139691 |
| | Mammalian Chk2 is a downstream effector of the ATM-dependent DNA damage checkpoint pathway | Q28141324 |
| | ATM phosphorylates histone H2AX in response to DNA double-strand breaks | Q28188651 |
| | Phosphorylation of threonine 68 promotes oligomerization and autophosphorylation of the Chk2 protein kinase via the forkhead-associated domain | Q28207961 |
| | DNA damage-induced G2-M checkpoint activation by histone H2AX and 53BP1 | Q28215916 |
| | Conservation of the Chk1 checkpoint pathway in mammals: linkage of DNA damage to Cdk regulation through Cdc25 | Q28247761 |
| | Mitotic and G2 checkpoint control: regulation of 14-3-3 protein binding by phosphorylation of Cdc25C on serine-216 | Q28247771 |
| | Selective induction of E2F1 in response to DNA damage, mediated by ATM-dependent phosphorylation | Q28344288 |
| | Regulating mammalian checkpoints through Cdc25 inactivation | Q28387035 |
| | Genomic instability in mice lacking histone H2AX | Q28589826 |
| | Rapid destruction of human Cdc25A in response to DNA damage | Q28611930 |
| | Regulation of G(2)/M events by Cdc25A through phosphorylation-dependent modulation of its stability | Q28612074 |
| | Mammalian G1- and S-phase checkpoints in response to DNA damage | Q29013238 |
| | Histone H2AX phosphorylation is dispensable for the initial recognition of DNA breaks | Q29617463 |
| | Determination of substrate motifs for human Chk1 and hCds1/Chk2 by the oriented peptide library approach. | Q30804251 |
| | Mebendazole elicits a potent antitumor effect on human cancer cell lines both in vitro and in vivo | Q34149540 |
| | Is cisplatin-induced cell death always produced by apoptosis? | Q34190171 |
| | The 3p21.3 tumor suppressor NPRL2 plays an important role in cisplatin-induced resistance in human non-small-cell lung cancer cells | Q34571308 |
| | Tumor suppressor genes on chromosome 3p involved in the pathogenesis of lung and other cancers | Q34935968 |
| P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P433 | issue | 8 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | cisplatin | Q412415 |
| | non-small-cell lung carcinoma | Q3658562 |
| P304 | page(s) | e11994 | |
| P577 | publication date | 2010-08-05 | |
| P1433 | published in | PLOS One | Q564954 |
| P1476 | title | NPRL2 sensitizes human non-small cell lung cancer (NSCLC) cells to cisplatin treatment by regulating key components in the DNA repair pathway | |
| P478 | volume | 5 | |