Cultivation of human keratinocyte stem cells: current and future clinical applications.

scientific article

Cultivation of human keratinocyte stem cells: current and future clinical applications. is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1007/BF02518885
P698PubMed publication ID10367472

P50authorMichele De LucaQ67571078
Graziella PellegriniQ39817850
P2093author name stringL Guerra
S Bondanza
P2860cites workMutations in the 180-kD bullous pemphigoid antigen (BPAG2), a hemidesmosomal transmembrane collagen (COL17A1), in generalized atrophic benign epidermolysis bullosaQ24308020
A homozygous mutation in the integrin alpha6 gene in junctional epidermolysis bullosa with pyloric atresiaQ24310172
Herlitz's junctional epidermolysis bullosa is linked to mutations in the gene (LAMC2) for the gamma 2 subunit of nicein/kalinin (LAMININ-5)Q24312169
Cloning of the laminin alpha 3 chain gene (LAMA3) and identification of a homozygous deletion in a patient with Herlitz junctional epidermolysis bullosaQ24319905
Characterization of point mutations in patients with X-linked ichthyosis. Effects on the structure and function of the steroid sulfatase proteinQ24321889
In vitro growth and differentiation of rabbit bulbar, fornix, and palpebral conjunctival epithelia. Implications on conjunctival epithelial transdifferentiation and stem cellsQ42511118
Suprabasal integrin expression in the epidermis of transgenic mice results in developmental defects and a phenotype resembling psoriasisQ42512612
Epithelial detachment due to absence of hemidesmosomes in integrin beta 4 null miceQ42519143
Non-Melanoma Skin Cancer Occurring in Patients Treated With PUVA Five to Ten Years After First TreatmentQ42519310
A common insertion mutation in COL7A1 in two Italian families with recessive dystrophic epidermolysis bullosaQ42629008
Laminin 5 binds the NC-1 domain of type VII collagenQ24676762
Integrins: versatility, modulation, and signaling in cell adhesionQ27860844
Integrin beta 4 mutations associated with junctional epidermolysis bullosa with pyloric atresiaQ28118736
A molecular defect in loricrin, the major component of the cornified cell envelope, underlies Vohwinkel's syndromeQ28282771
A Homozygous Nonsense Mutation in the β3 Chain Gene of Laminin 5 (LAMB3) in Herlitz Junctional Epidermolysis BullosaQ28298888
Mutations of keratinocyte transglutaminase in lamellar ichthyosisQ28305640
Beta4 integrin is required for hemidesmosome formation, cell adhesion and cell survivalQ28592841
Serial cultivation of strains of human epidermal keratinocytes: the formation of keratinizing colonies from single cellsQ29614425
Label-retaining cells reside in the bulge area of pilosebaceous unit: implications for follicular stem cells, hair cycle, and skin carcinogenesisQ29615762
Marrow stromal cells as stem cells for nonhematopoietic tissuesQ29618770
Polarized integrin mediates human keratinocyte adhesion to basal laminaQ33777898
Regulation of interleukin 1 and its receptor in human keratinocytesQ33837915
Alpha 6 beta 4 integrin heterodimer is a component of hemidesmosomesQ33899956
Growth of cultured human epidermal cells into multiple epithelia suitable for graftingQ33979849
Cell migration is essential for sustained growth of keratinocyte colonies: the roles of transforming growth factor-alpha and epidermal growth factorQ34181051
Molecular studies of deletions at the human steroid sulfatase locusQ34316988
Type VII collagen, anchoring fibrils, and epidermolysis bullosaQ34354365
Three clonal types of keratinocyte with different capacities for multiplicationQ34393745
Human keratin diseases: hereditary fragility of specific epithelial tissuesQ34416078
A model of corrective gene transfer in X-linked ichthyosisQ34428074
Frontiers in keratodermas: pushing the envelopeQ34430105
Genetic Skin Disorders of KeratinQ35159068
Molecular genetics of epidermolysis bullosaQ35319422
Survival of cultured allografts in patients with burns assessed with probe specific for Y chromosomeQ35710404
Genetically modified keratinocytes transplanted to wounds reconstitute the epidermisQ35779226
Compound heterozygosity for COL7A1 mutations in twins with dystrophic epidermolysis bullosa: a recessive paternal deletion/insertion mutation and a dominant negative maternal glycine substitution result in a severe phenotypeQ35881857
Transgenic studies with a keratin promoter-driven growth hormone transgene: prospects for gene therapyQ35906330
Culture of human epitheliumQ35949812
Differentiation-related expression of a major 64K corneal keratin in vivo and in culture suggests limbal location of corneal epithelial stem cellsQ36212986
Basic fibroblast growth factor from human keratinocytes is a natural mitogen for melanocytes.Q36219364
Epidermal differentiation: the bare essentialsQ36224142
α3β1 Integrin Is Required for Normal Development of the Epidermal Basement MembraneQ36274145
A recombinant tail-less integrin beta 4 subunit disrupts hemidesmosomes, but does not suppress alpha 6 beta 4-mediated cell adhesion to laminins.Q36382518
Evidence for keratinocyte stem cells in vitro: long term engraftment and persistence of transgene expression from retrovirus-transduced keratinocytesQ36472749
Integrin alpha 6/beta 4 complex is located in hemidesmosomes, suggesting a major role in epidermal cell-basement membrane adhesionQ36529725
Transforming growth factor-beta 1 modulates beta 1 and beta 5 integrin receptors and induces the de novo expression of the alpha v beta 6 heterodimer in normal human keratinocytes: implications for wound healing.Q42771319
Clinical application of autologous cultured epithelia for the treatment of burn wounds and burn scarsQ42803341
Growth and differentiation of human epidermal cultures used as auto- and allografts in humansQ42809155
Rabbit conjunctival and corneal epithelial cells belong to two separate lineages.Q42816176
Genetically modified skin to treat disease: potential and limitationsQ42832712
Conjunctival epithelial cells do not transdifferentiate in organotypic cultures: expression of K12 keratin is restricted to corneal epithelium.Q42833723
Cultured epithelial autografts for giant congenital neviQ43465884
Evaluation of Graftskin composite grafts on full-thickness wounds on athymic mice.Q43748892
Treatment of leg ulcers with cryopreserved allogeneic cultured epithelium. A multicenter studyQ43984937
Transplantation of retrovirus-transduced canine keratinocytes expressing the beta-galactosidase geneQ45867251
Gene transfer into cultured human epidermis and its transplantation onto immunodeficient mice: an experimental model for somatic gene therapyQ45872066
Ex vivo and in vivo gene transfer to the skin using replication-deficient recombinant adenovirus vectorsQ45872692
Towards gene therapy for haemophilia B using primary human keratinocytesQ45875232
Keratinocyte gene therapy for adenosine deaminase deficiency: a model approach for inherited metabolic disordersQ45882335
The importance of epidermal stem cells in keratinocyte-mediated gene therapy.Q45883224
Evaluation of artificial skin (Integra) in a rodent modelQ46578885
Corrective transduction of human epidermal stem cells in laminin-5-dependent junctional epidermolysis bullosa.Q47895646
Vitiligo: repigmentation with dermabrasion and thin split-thickness skin graft.Q51607109
Absence of integrin alpha 6 leads to epidermolysis bullosa and neonatal death in mice.Q52200996
Surgical combination therapy for vitiligo and piebaldism.Q53638047
Rejection, after a slightly prolonged survival time, of Langerhans cell-free allogeneic cultured epidermis used for wound coverage in humans.Q53760608
Epidermal grafting. An original technique and its application in achromic and granulating areas.Q53847940
Cultured epidermal autografts and allodermis combination for permanent burn wound coverage.Q54218209
Malignant melanoma in patients treated for psoriasis with methoxsalen (psoralen) and ultraviolet A radiation (PUVA). The PUVA Follow-Up Study.Q54340187
Separation of human epidermal stem cells from transit amplifying cells on the basis of differences in integrin function and expressionQ57385116
Cytokeratin patterns of human oral epithelia: Differences in cytokeratin synthesis in gingival epithelium and the adjacent alveolar mucosaQ58439244
Production and auto-induction of transforming growth factor-α in human keratinocytesQ59048981
Long-term restoration of damaged corneal surfaces with autologous cultivated corneal epitheliumQ60289643
Location of stem cells of human hair follicles by clonal analysisQ64450268
Biochemical transformation of regenerating ocular surface epitheliumQ67541512
Comparison of limbal and conjunctival autograft transplantation in corneal surface reconstruction in rabbitsQ67656979
New techniques for the grafting of cultured human epidermal cells onto athymic animalsQ67933124
Epidermal grafting using the tops of suction blisters in the treatment of vitiligoQ67946187
Treatment of refractory and stable vitiligo by transplantation of in vitro cultured epidermal autografts bearing melanocytesQ68079831
Permanent coverage of full skin thickness burns with autologous cultured epidermis and reepithelialization of partial skin thickness lesions induced by allogeneic cultured epidermis: a multicentre study in the treatment of childrenQ68083296
Wound bed preparation: approaches to replacement of dermisQ68106744
Cultured epithelium as a skin substituteQ68169643
Composite autologous-allogeneic skin replacement: development and clinical applicationQ68191467
Culture grafted leg ulcersQ68194512
Wound coverage with cultured autologous keratinocytes: use after burn wound excision, including biopsy followupQ68277171
The corneoscleral limbus in human corneal epithelial wound healingQ68615894
Fresh versus cryopreserved cultured allografts for the treatment of chronic skin ulcersQ68697437
Genital tumors among men with psoriasis exposed to psoralens and ultraviolet A radiation (PUVA) and ultraviolet B radiation. The Photochemotherapy Follow-up StudyQ68741721
Cultured epidermis for the coverage of massive burn wounds. A single center experienceQ68823489
Treatment of posterior hypospadias by the autologous graft of cultured urethral epitheliumQ68868964
Antigen presentation by Langerhans cells in vivo: donor-derived Ia+ Langerhans cells are required for induction of delayed-type hypersensitivity but not for cytotoxic T lymphocyte responses to alloantigensQ68878604
A parathyroid hormone-like protein from cultured human keratinocytesQ68951195
Use of cultured epidermal autografts and dermal allografts as skin replacement after burn injuryQ68961439
Progressive replacement of human cultured epithelial allografts by recipient cells as evidenced by HLA class I antigens expressionQ69005222
Reconstitution of structure and cell function in human skin grafts derived from cryopreserved allogeneic dermis and autologous cultured keratinocytesQ69042228
Rejection of cultured keratinocyte allografts in the rat. Clinical implications and a possible clue to the enigma of skin graft rejectionQ69088979
Response to cosmetic disfigurement: patients with vitiligoQ69125675
Autograft Repigmentation of LeukodermaQ69175297
Transplantation of human melanocytesQ69225821
Expression of an exogenous growth hormone gene by transplantable human epidermal cellsQ69249459
Multicentre experience in the treatment of burns with autologous and allogenic cultured epithelium, fresh or preserved in a frozen stateQ69557356
Limbal autograft transplantation for ocular surface disordersQ69657610
Transplantation of in vitro-cultured epidermis bearing melanocytes for repigmenting vitiligoQ69700752
Treatment of localized vitiligo by autologous minigraftingQ70219350
Permanent coverage of large burn wounds with autologous cultured human epitheliumQ70370012
Management of vitiligoQ70566739
Vitiligo: treatment by dermabrasion and epithelial sheet grafting--a preliminary reportQ70723435
The Bladder Mucosal Graft Technique for Hypospadias RepairQ70768585
Free autogenous gingival grafts. I. Principles of successful graftingQ70936532
One-stage urethroplasty for hypospadias using a tube constructed with bladder mucosa-- a new procedureQ71056768
Vitiligo: treatment by dermabrasion and epithelial sheet graftingQ72055707
Autotransplantation in vitiligo: treatment with epidermal grafts and cultured melanocytesQ72213241
Repigmentation of vitiligo by transplantation of cultured autologous melanocytesQ72213243
Treatment of stable vitiligo with autologous epidermal grafting and PUVAQ72239735
Label-retaining cells are preferentially located in fornical epithelium: implications on conjunctival epithelial homeostasisQ72410727
Grafting of burns with cultured epithelium prepared from autologous epidermal cellsQ72445637
Epidermal stem cellsQ72701775
Acceleration of skin regeneration from cultured epithelial autografts by transplantation to homograft dermisQ72755610
Approaches to gene transfer in keratinocytesQ72813269
Human allograft limbal transplantation for corneal surface reconstructionQ72894102
One-step treatment of proximal hypospadias by the autologous graft of cultured urethral epitheliumQ72923075
A multicenter clinical trial of a biosynthetic skin replacement, Dermagraft-TC, compared with cryopreserved human cadaver skin for temporary coverage of excised burn woundsQ73139370
The use of a permanent dermal allograft in full-thickness burns of the hand and foot: a report of three casesQ73206575
The non-MHC transplantation antigens: neither weak nor minorQ85699993
The integrin alpha 6 beta 4 is a laminin receptorQ36531324
Corneal re-epithelialization from the conjunctiva.Q36657308
A hyaluronic acid membrane delivery system for cultured keratinocytes: clinical "take" rates in the porcine kerato-dermal modelQ36863452
Clonal analysis of stably transduced human epidermal stem cells in cultureQ37339157
Cell size as a determinant of the clone-forming ability of human keratinocytesQ37528349
Revised clinical and laboratory criteria for subtypes of inherited epidermolysis bullosa. A consensus report by the Subcommittee on Diagnosis and Classification of the National Epidermolysis Bullosa RegistryQ37648655
Long-term transplantation of canine keratinocytes made resistant to G418 through retrovirus-mediated gene transferQ37723721
Evidence for an epidermal cytokine networkQ38010155
Terminal differentiation of epidermal keratinocytesQ38782850
Repigmentation in vitiligo vulgaris by autologous minigrafting: results in nineteen patientsQ39368984
Stem cell conceptsQ39806514
The keratinocyte as differentiated cell typeQ40099057
Immunobiology of tissue transplantation: a return to the passenger leukocyte conceptQ40216361
Expression, topography, and function of integrin receptors are severely altered in keratinocytes from involved and uninvolved psoriatic skinQ40343677
Defects in the barrierQ40396660
Hypospadias repairQ40782713
Integrins and their ligands.Q40817349
Vitiligo: where do we stand?Q40820967
Hair follicles, stem cells, and skin cancerQ40880047
Vitiligo. An overview of therapeutic approachesQ40898954
Transglutaminase 1 delivery to lamellar ichthyosis keratinocytesQ40919767
Corrective gene transfer in the human skin disorder lamellar ichthyosisQ40922828
Current treatment of severely burned patientsQ40941696
Molecular complexity of the cutaneous basement membrane zone. Revelations from the paradigms of epidermolysis bullosaQ40951954
Epidermis: an attractive target tissue for gene therapyQ41013053
Influence of matching for HLA-DR antigens on skin graft survivalQ41072827
Signal transduction by the alpha 6 beta 4 integrin: charting the path between laminin binding and nuclear eventsQ41107479
Conjunctival transdifferentiation is due to the incomplete removal of limbal basal epitheliumQ41206318
Hemidesmosomes: roles in adhesion, signaling and human diseasesQ41238874
Recent investigations on vitiligo vulgarisQ41321641
The alpha 6 beta 4 integrin is a receptor for both laminin and kalininQ41476163
Molecular basis of congenital hypopigmentary disorders in humans: a reviewQ41487071
Human epithelial cells induce human melanocyte growth in vitro but only skin keratinocytes regulate its proper differentiation in the absence of dermisQ41563414
Human growth hormone in the blood of athymic mice grafted with cultures of hormone-secreting human keratinocytesQ41716023
Evidence that human oral epithelium reconstituted in vitro and transplanted onto patients with defects in the oral mucosa retains properties of the original donor siteQ41844185
Use of human keratinocytes cultured on fibrin glue in the treatment of burn woundsQ41866681
A surgical treatment for vitiligo: autologous cultured-epithelial graftsQ41900575
Retrovirus-mediated transduction of cultured epidermal keratinocytesQ42003487
Sustainability of keratinocyte gene transfer and cell survival in vivoQ42440060
Treatment of extensive hypomelanosis with autologous cultured epitheliumQ42441610
Cultured epidermal autografts and allografts: A study of differentiation and allograft survivalQ42465915
Growth-regulated synthesis and secretion of biologically active nerve growth factor by human keratinocytesQ42467398
Polarized expression of integrin receptors (alpha 6 beta 4, alpha 2 beta 1, alpha 3 beta 1, and alpha v beta 5) and their relationship with the cytoskeleton and basement membrane matrix in cultured human keratinocytesQ42470291
Changes in keratinocyte adhesion during terminal differentiation: reduction in fibronectin binding precedes alpha 5 beta 1 integrin loss from the cell surfaceQ42479002
Nerve growth factor binds to normal human keratinocytes through high and low affinity receptors and stimulates their growth by a novel autocrine loopQ42483932
Identification of a homozygous one-basepair deletion in exon 14 of the LAMB3 gene in a patient with Herlitz junctional epidermolysis bullosa and prenatal diagnosis in a family at risk for recurrenceQ42484508
Coculture of human keratinocytes and melanocytes: differentiated melanocytes are physiologically organized in the basal layer of the cultured epithelium.Q42489193
Skin regenerated from cultured epithelial autografts on full-thickness burn wounds from 6 days to 5 years after grafting. A light, electron microscopic and immunohistochemical studyQ42490113
Existence of slow-cycling limbal epithelial basal cells that can be preferentially stimulated to proliferate: implications on epithelial stem cellsQ42497816
Correction of steroid sulfatase deficiency by gene transfer into basal cells of tissue-cultured epidermis from patients with recessive X-linked ichthyosisQ42503541
P433issue6
P921main subjectkeratinocyteQ1473931
P304page(s)778-790
P577publication date1998-11-01
P1433published inMedical & Biological Engineering & ComputingQ6806252
P1476titleCultivation of human keratinocyte stem cells: current and future clinical applications
P478volume36

Reverse relations

cites work (P2860)
Q51544904Bioreactor microcarrier cell culture system (Bio-MCCS) for large-scale production of autologous melanocytes.
Q30729472Culture of rat keratinocytes with acellular pig dermis
Q34168004Functional characterization of cultured keratinocytes after acute cutaneous burn injury
Q36685593High-level secretion of growth hormone by retrovirally transduced primary human keratinocytes: prospects for an animal model of cutaneous gene therapy.
Q54360046Human forniceal region is the stem cell-rich zone of the conjunctival epithelium.
Q35629072Hypopigmentary skin disorders: current treatment options and future directions
Q47831661Immunolocalisation of leukaemia inhibitory factor in the cornea.
Q44606542Increases in weight of growth hormone‐deficient and immunodeficient (lit/scid) dwarf mice after grafting of hGH‐ secreting, primary human keratinocytes
Q35152771Large-scale expansion of mammalian neural stem cells: a review
Q36256645Location and clonal analysis of stem cells and their differentiated progeny in the human ocular surface.
Q41956259Long-term type VII collagen restoration to human epidermolysis bullosa skin tissue
Q64890247Molecular markers for corneal epithelial cells in larval vs. adult Xenopus frogs.
Q36667441Multipotent adult progenitor cell and stem cell plasticity
Q38562423Oral keratinocyte stem/progenitor cells: specific markers, molecular signaling pathways and potential uses
Q33817019Reduced mitochondrial properties in putative progenitor/stem cells of human keratinocytes.
Q28066200Skin tissue engineering advances in severe burns: review and therapeutic applications
Q26779833Stem cells: An insight into the therapeutic aspects from medical and dental perspectives
Q35962945The engineering of tissues using progenitor cells
Q34769303The international workshop on meibomian gland dysfunction: report of the subcommittee on anatomy, physiology, and pathophysiology of the meibomian gland
Q40738230Tissue-specific expression and long-term deposition of human collagen VII in the skin of transgenic mice: implications for gene therapy
Q42455498Transfection of normal human epidermal keratinocytes with lipid/dna complexes in vitro.
Q81354683[Other surgical therapies for cornea burns]

Search more.