T cell factor 1 initiates the T helper type 2 fate by inducing the transcription factor GATA-3 and repressing interferon-gamma.

scientific article

T cell factor 1 initiates the T helper type 2 fate by inducing the transcription factor GATA-3 and repressing interferon-gamma. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/NI.1762
P932PMC publication ID2824257
P698PubMed publication ID19648923
P5875ResearchGate publication ID26711296

P50authorArchna SharmaQ48737705
P2093author name stringMarian L Waterman
Sun Young Oh
Beibei Wu
Qing Yu
Jyoti Misra Sen
Zhou Zhu
M Zulfiquer Hossain
Hyung-Geun Moon
Hansen Du
Karen E Leeds
Theresa M Salay
P2860cites workThe Xenopus Wnt effector XTcf-3 interacts with Groucho-related transcriptional repressorsQ22003989
Identification of BMP and activin membrane-bound inhibitor (BAMBI), an inhibitor of transforming growth factor-beta signaling, as a target of the beta-catenin pathway in colorectal tumor cellsQ24301259
Cutting edge: Identification of an alternative GATA-3 promoter directing tissue-specific gene expression in mouse and humanQ28215575
Anteriorization of neural fate by inhibitor of beta-catenin and T cell factor (ICAT), a negative regulator of Wnt signalingQ28585925
Deletion of β-catenin impairs T cell developmentQ28587501
Notch directly regulates Gata3 expression during T helper 2 cell differentiationQ28594834
Direct regulation of Gata3 expression determines the T helper differentiation potential of NotchQ28594879
XTcf-3 transcription factor mediates beta-catenin-induced axis formation in Xenopus embryosQ28619032
The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cellsQ29614226
Inhibitors of gamma-secretase block in vivo and in vitro T helper type 1 polarization by preventing Notch upregulation of Tbx21Q95814547
The lineage decisions of helper T cellsQ29614841
Mapping Wnt/beta-catenin signaling during mouse development and in colorectal tumorsQ29619814
Wnt signaling induces matrix metalloproteinase expression and regulates T cell transmigrationQ30479330
Notch and presenilin regulate cellular expansion and cytokine secretion but cannot instruct Th1/Th2 fate acquisitionQ33356044
T-cell priming by type-1 and type-2 polarized dendritic cells: the concept of a third signalQ33774232
Lineage commitment in the immune system: the T helper lymphocyte grows up.Q33970744
TCF: Lady Justice casting the final verdict on the outcome of Wnt signallingQ34122210
Inducible targeting of IL-13 to the adult lung causes matrix metalloproteinase- and cathepsin-dependent emphysemaQ34457903
Human naive CD8 T cells down-regulate expression of the WNT pathway transcription factors lymphoid enhancer binding factor 1 and transcription factor 7 (T cell factor-1) following antigen encounter in vitro and in vivoQ34486226
WNT signalling and haematopoiesis: a WNT-WNT situationQ35998797
A unique DNA binding domain converts T-cell factors into strong Wnt effectorsQ36315950
Beta 2-microglobulin-dependent NK1.1+ T cells are not essential for T helper cell 2 immune responsesQ36367480
Regulation of Th2 differentiation and Il4 locus accessibility.Q36427376
Beta-catenin regulates positive selection of thymocytes but not lineage commitmentQ36507467
A three-cell model for activation of naïve T helper cells.Q36546682
The proto-oncogene c-maf is responsible for tissue-specific expression of interleukin-4.Q36804149
The canonical Wnt signaling pathway plays an important role in lymphopoiesis and hematopoiesisQ36916471
ICAT expression disrupts beta-catenin-TCF interactions and impairs survival of thymocytes and activated mature T cellsQ36916479
Pre-TCR-induced beta-catenin facilitates traversal through beta-selectionQ37132613
WNT signalling in the immune system: WNT is spreading its wingsQ37212748
Conditional deletion of Gata3 shows its essential function in T(H)1-T(H)2 responses.Q39697358
Prostaglandin E2 promotes colon cancer cell growth through a Gs-axin-beta-catenin signaling axis.Q40350197
Prostaglandin E2 Stimulates the beta-catenin/T cell factor-dependent transcription in colon cancerQ40420990
Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin productionQ40849898
Transcription factor GATA-3 is differentially expressed in murine Th1 and Th2 cells and controls Th2-specific expression of the interleukin-5 geneQ41093086
Induction of interleukin 4 (IL-4) expression in T helper (Th) cells is not dependent on IL-4 from non-Th cellsQ42942261
Prostaglandin E(2) is a selective inducer of interleukin-12 p40 (IL-12p40) production and an inhibitor of bioactive IL-12p70 heterodimerQ43615371
Francisella tularensis-infected macrophages release prostaglandin E2 that blocks T cell proliferation and promotes a Th2-like responseQ44512637
beta-Catenin expression enhances generation of mature thymocytesQ47351273
Regulation of alphabeta/gammadelta T cell lineage commitment and peripheral T cell responses by Notch/RBP-J signalingQ47607371
Instruction of distinct CD4 T helper cell fates by different notch ligands on antigen-presenting cellsQ47619638
GFP transgenic mice reveal active canonical Wnt signal in neonatal brain and in adult liver and spleenQ48299832
Transcriptional regulation of GATA3 in T helper cells by the integrated activities of transcription factors downstream of the interleukin-4 receptor and T cell receptor.Q51945372
Stat6 is required for mediating responses to IL-4 and for development of Th2 cells.Q55066450
An HMG-box-containing T-cell factor required for thymocyte differentiation.Q59058515
Early production of IL-4 and induction of Th2 responses in the lymph node originate from an MHC class I-independent CD4+NK1.1- T cell populationQ71755877
Immunoglobulin E production in the absence of interleukin-4-secreting CD1-dependent cellsQ73038938
Tcf-1-mediated transcription in T lymphocytes: differential role for glycogen synthase kinase-3 in fibroblasts and T cellsQ77378921
Beta-catenin stabilization extends regulatory T cell survival and induces anergy in nonregulatory T cellsQ80622205
P433issue9
P407language of work or nameEnglishQ1860
P304page(s)992-999
P577publication date2009-08-02
P1433published inNature ImmunologyQ1071725
P1476titleT cell factor 1 initiates the T helper type 2 fate by inducing the transcription factor GATA-3 and repressing interferon-gamma
P478volume10

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