Role of p62 in the suppression of inflammatory cytokine production by adiponectin in macrophages: Involvement of autophagy and p21/Nrf2 axis

scientific article

Role of p62 in the suppression of inflammatory cytokine production by adiponectin in macrophages: Involvement of autophagy and p21/Nrf2 axis is …
instance of (P31):
scholarly articleQ13442814

External links are
P6179Dimensions Publication ID1084130588
P356DOI10.1038/S41598-017-00456-6
P8608Fatcat IDrelease_kgdxiv23kbawrccauybcbj5rwq
P932PMC publication ID5428427
P698PubMed publication ID28341848

P2093author name stringPil-Hoon Park
Nirmala Tilija Pun
P2860cites workThe atypical protein kinase C-interacting protein p62 is a scaffold for NF-kappaB activation by nerve growth factorQ24290913
p62/SQSTM1 is a target gene for transcription factor NRF2 and creates a positive feedback loop by inducing antioxidant response element-driven gene transcriptionQ24310885
Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate proteasomal degradation of Nrf2Q24563807
Autophagy protects against active tuberculosis by suppressing bacterial burden and inflammationQ24609294
The atypical PKC-interacting protein p62 channels NF-kappaB activation by the IL-1-TRAF6 pathwayQ24630760
Direct interaction between Nrf2 and p21(Cip1/WAF1) upregulates the Nrf2-mediated antioxidant responseQ24646029
Value of monitoring Nrf2 activity for the detection of chemical and oxidative stressQ26778360
Autophagy and disease: always two sides to a problemQ26995401
Globular adiponectin modulates expression of programmed cell death 4 and miR-21 in RAW 264.7 macrophages through the MAPK/NF-κB pathway.Q51062140
Regulation of macrophage activation and septic shock susceptibility via p21(WAF1/CIP1).Q51815091
Adiponectin suppresses angiotensin II-induced inflammation and cardiac fibrosis through activation of macrophage autophagy.Q54215442
Suppression of autophagy sensitizes Kupffer cells to endotoxin.Q54511206
A possible involvement of p62/sequestosome-1 in the process of biliary epithelial autophagy and senescence in primary biliary cirrhosis.Q54548926
Targeted disruption of AdipoR1 and AdipoR2 causes abrogation of adiponectin binding and metabolic actionsQ57249776
NBR1 and p62 as cargo receptors for selective autophagy of ubiquitinated targetsQ57269938
Autophagy is activated by apoptotic signalling in sympathetic neurons: an alternative mechanism of death executionQ73216536
Short-term treatment of RAW264.7 macrophages with adiponectin increases tumor necrosis factor-alpha (TNF-alpha) expression via ERK1/2 activation and Egr-1 expression: role of TNF-alpha in adiponectin-stimulated interleukin-10 productionQ38301259
Adiponectin stimulates autophagy and reduces oxidative stress to enhance insulin sensitivity during high-fat diet feeding in mice.Q38970746
Modulation of Atg5 expression by globular adiponectin contributes to autophagy flux and suppression of ethanol-induced cell death in liver cellsQ39019837
Knockdown of p62/sequestosome 1 attenuates autophagy and inhibits colorectal cancer cell growthQ39092070
Activation of autophagy by globular adiponectin attenuates ethanol-induced apoptosis in HepG2 cells: involvement of AMPK/FoxO3A axisQ39149665
Autophagy protein p62/SQSTM1 is involved in HAMLET-induced cell death by modulating apotosis in U87MG cellsQ39177430
Anti-inflammatory activity of a globular adiponectin function on RAW 264 cells stimulated by lipopolysaccharide from Aggregatibacter actinomycetemcomitans.Q39833816
Pivotal role of the cyclin-dependent kinase inhibitor p21WAF1/CIP1 in apoptosis and autophagyQ40062826
The p62 scaffold regulates nerve growth factor-induced NF-kappaB activation by influencing TRAF6 polyubiquitinationQ40389327
Generation of globular fragment of adiponectin by leukocyte elastase secreted by monocytic cell line THP-1.Q40495451
Adiponectin induces the anti-inflammatory cytokines IL-10 and IL-1RA in human leukocytesQ40515404
Transcription factor NFE2L2/NRF2 is a regulator of macroautophagy genes.Q41575678
Inhibitory Effect of 3-(4-Hydroxyphenyl)-1-(thiophen-2-yl) prop-2-en-1-one, a Chalcone Derivative on MCP-1 Expression in Macrophages via Inhibition of ROS and Akt SignalingQ42182595
Both adiponectin and interleukin-10 inhibit LPS-induced activation of the NF-κB pathway in 3T3-L1 adipocytes.Q42803687
Plasma adiponectin concentrations predict insulin sensitivity of both glucose and lipid metabolismQ44286338
Adiponectin inhibits endothelial synthesis of interleukin-8.Q46790564
P21Cip1/WAF1 downregulation is required for efficient PCNA ubiquitination after UV irradiationQ46890870
The helminth product ES-62 protects against septic shock via Toll-like receptor 4-dependent autophagosomal degradation of the adaptor MyD88Q28115132
Oxidative stress and autophagy: the clash between damage and metabolic needsQ28387805
Bcl-2-dependent upregulation of autophagy by sequestosome 1/p62 in vitroQ28397812
Keap1 recruits Neh2 through binding to ETGE and DLG motifs: characterization of the two-site molecular recognition modelQ28910182
Paradoxical decrease of an adipose-specific protein, adiponectin, in obesityQ29616103
Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndromeQ29619211
Adiponectin and adiponectin receptorsQ29620248
Nrf2 induces cisplatin resistance through activation of autophagy in ovarian carcinomaQ33582954
Caspase-independent programmed cell death with necrotic morphologyQ33669492
The sequestosome 1/p62 attenuates cytokine gene expression in activated macrophages by inhibiting IFN regulatory factor 8 and TNF receptor-associated factor 6/NF-kappaB activityQ34118232
Proteolytic cleavage product of 30-kDa adipocyte complement-related protein increases fatty acid oxidation in muscle and causes weight loss in miceQ34118282
Regulation of MyD88 Aggregation and the MyD88-dependent Signaling Pathway by Sequestosome 1 and Histone Deacetylase 6Q34285271
Nrf2-mediated induction of p62 controls Toll-like receptor-4-driven aggresome-like induced structure formation and autophagic degradationQ34533982
The adaptor protein p62 is involved in RANKL-induced autophagy and osteoclastogenesisQ34572745
Effect of adiponectin on kidney crystal formation in metabolic syndrome model mice via inhibition of inflammation and apoptosisQ34695462
Adiponectin increases secretion of rat submandibular gland via adiponectin receptors-mediated AMPK signalingQ34718458
The signaling adaptor p62 is an important NF-kappaB mediator in tumorigenesisQ34768397
Obesity, adiponectin and vascular inflammatory diseaseQ35587168
Globular Adiponectin Causes Tolerance to LPS-Induced TNF-α Expression via Autophagy Induction in RAW 264.7 Macrophages: Involvement of SIRT1/FoxO3A AxisQ35626616
Regulation of Toll-like receptor signaling by NDP52-mediated selective autophagy is normally inactivated by A20Q35775604
Adiponectin normalizes LPS-stimulated TNF-alpha production by rat Kupffer cells after chronic ethanol feedingQ35989242
Cytotoxic effects of bortezomib in myelodysplastic syndrome/acute myeloid leukemia depend on autophagy-mediated lysosomal degradation of TRAF6 and repression of PSMA1.Q36141927
CDK inhibitors (p16/p19/p21) induce senescence and autophagy in cancer-associated fibroblasts, "fueling" tumor growth via paracrine interactions, without an increase in neo-angiogenesisQ36338756
Resveratrol overcomes gefitinib resistance by increasing the intracellular gefitinib concentration and triggering apoptosis, autophagy and senescence in PC9/G NSCLC cellsQ36346111
Autophagy is activated to protect against endotoxic acute kidney injuryQ36621399
Structure, function and regulation of the Toll/IL-1 receptor adaptor proteinsQ36898672
Mechanisms for the anti-inflammatory effects of adiponectin in macrophagesQ37108874
Autophagy and aging: keeping that old broom workingQ37321185
Lipopolysaccharide stimulates p62-dependent autophagy-like aggregate clearance in hepatocytesQ37603188
Physiological significance of selective degradation of p62 by autophagyQ37691820
Modulation of inflammation by autophagy: consequences for Crohn's disease.Q37985184
p62: a versatile multitasker takes on cancerQ37994350
Adiponectin as a tissue regenerating hormone: more than a metabolic functionQ38169963
The machinery of macroautophagyQ38173673
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectautophagyQ288322
P304page(s)393
P577publication date2017-03-24
P1433published inScientific ReportsQ2261792
P1476titleRole of p62 in the suppression of inflammatory cytokine production by adiponectin in macrophages: Involvement of autophagy and p21/Nrf2 axis
P478volume7

Reverse relations

cites work (P2860)
Q96348526Alpha1-antitrypsin protects lung cancer cells from staurosporine-induced apoptosis: the role of bacterial lipopolysaccharide
Q58715955Andrographolide Protects PC12 Cells Against β-Amyloid-Induced Autophagy-Associated Cell Death Through Activation of the Nrf2-Mediated p62 Signaling Pathway
Q47099058Cordyceps militaris improves the survival of Dahl salt-sensitive hypertensive rats possibly via influences of mitochondria and autophagy functions
Q91719344Glycoconjugates of Gram-negative bacteria and parasitic protozoa - are they similar in orchestrating the innate immune response?
Q59329245Selective Autophagy and Xenophagy in Infection and Disease
Q49960522Variations in ADIPOR1 But Not ADIPOR2 are Associated With Hypertriglyceridemia and Diabetes in an Admixed Latin American Population.
Q90002304ZFP36L1 and AUF1 Induction Contribute to the Suppression of Inflammatory Mediators Expression by Globular Adiponectin via Autophagy Induction in Macrophages
Q58697771p62 /SQSTM1 coding plasmid prevents age related macular degeneration in a rat model
Q91691903p62 Negatively Regulates TLR4 Signaling via Functional Regulation of the TRAF6-ECSIT Complex

Search more.