Phospholipase D2 Enhances Epidermal Growth Factor-Induced Akt Activation in EL4 Lymphoma Cells

scientific article

Phospholipase D2 Enhances Epidermal Growth Factor-Induced Akt Activation in EL4 Lymphoma Cells is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3390/PH3072045
P932PMC publication ID4036664
P698PubMed publication ID27713341
P5875ResearchGate publication ID45267244

P2093author name stringKathryn E Meier
Manpreet S Chahal
Daniel J Brauner
P2860cites workADP-ribosylation factor 4 small GTPase mediates epidermal growth factor receptor-dependent phospholipase D2 activationQ24320321
The direct interaction of phospholipase C-gamma 1 with phospholipase D2 is important for epidermal growth factor signalingQ28184932
Phospholipase D in cell proliferation and cancerQ28205631
The MARCKS family of phospholipid binding proteins: regulation of phospholipase D and other cellular componentsQ28253543
Phospholipase DQ28253553
Integrin regulation of epidermal growth factor (EGF) receptor and of EGF-dependent responsesQ28262897
Phospholipase D2 acts as an essential adaptor protein in the activation of Syk in antigen-stimulated mast cellsQ28570396
The cloning of a rat peptidoglycan recognition protein (PGRP) and its induction in brain by sleep deprivationQ28581199
EGFR antagonists in cancer treatmentQ29616740
Munc-18-1 inhibits phospholipase D activity by direct interaction in an epidermal growth factor-reversible manner.Q30273585
Comparative genomic sequence analysis and isolation of human and mouse alternative EGFR transcripts encoding truncated receptor isoforms.Q30650378
Down regulation of the PEDF gene in human lens epithelium cells changed the expression of proteins vimentin and alphaB-crystallinQ33608348
Expression of phospholipase D isoforms in mammalian cellsQ33698811
Localization and possible functions of phospholipase D isozymesQ33698828
Increased activity and intranuclear expression of phospholipase D2 in human renal cancerQ73456499
Phosphorylation of paxillin via the ERK mitogen-activated protein kinase cascade in EL4 thymoma cellsQ73643337
Regulation of phospholipase DQ78430629
Phospholipase D2-derived phosphatidic acid binds to and activates ribosomal p70 S6 kinase independently of mTORQ79622069
Receptor transactivation cascades. Focus on "Effects of alpha1D-adrenergic receptors on shedding of biologically active EGF in freshly isolated lacrimal gland epithelial cells"Q79999741
Role of phospholipase D2/phosphatidic acid signal transduction in micro- and delta-opioid receptor endocytosisQ95800345
Continual production of phosphatidic acid by phospholipase D is essential for antigen-stimulated membrane ruffling in cultured mast cellsQ34168797
Epidermal growth factor receptor: mechanisms of activation and signalling.Q34185055
Role of phospholipase D in agonist-stimulated lysophosphatidic acid synthesis by ovarian cancer cellsQ34210735
Regulation and possible role of mammalian phospholipase D in cellular functionsQ34548402
A novel pathway regulating the mammalian target of rapamycin (mTOR) signalingQ34863186
The regulation of phospholipase D by inositol phospholipids and small GTPasesQ34980705
Phospholipase D1 and potential targets of its hydrolysis product, phosphatidic acidQ35052937
Phospholipase D and choline kinase: their role in cancer development and their potential as drug targetsQ35573655
Biology of the epidermal growth factor receptor family.Q35784977
Effects of active and inactive phospholipase D2 on signal transduction, adhesion, migration, invasion, and metastasis in EL4 lymphoma cellsQ39975730
RasGRP1 confers the phorbol ester-sensitive phenotype to EL4 lymphoma cellsQ40215592
Alternative phospholipase D/mTOR survival signal in human breast cancer cellsQ40484574
Elevated phospholipase D activity induces apoptosis in normal rat fibroblastsQ40693370
Mitogenic phospholipase D activity is restricted to caveolin-enriched membrane microdomainsQ40871016
P2Y12 receptor signalling towards PKB proceeds through IGF-I receptor cross-talk and requires activation of Src, Pyk2 and Rap1.Q42485518
Phospholipase D overcomes cell cycle arrest induced by high-intensity Raf signalingQ42814716
Association of a polymorphism of the phospholipase D2 gene with the prevalence of colorectal cancerQ45858801
Calibrated user-friendly reverse transcriptase-PCR assay: quantitation of epidermal growth factor receptor mRNA.Q47980420
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue7
P1104number of pages14
P304page(s)2045-2058
P577publication date2010-07-02
P1433published inPharmaceuticalsQ15750667
P1476titlePhospholipase D2 Enhances Epidermal Growth Factor-Induced Akt Activation in EL4 Lymphoma Cells
P478volume3

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cites work (P2860)
Q37569984Differential Expression of Ccn4 and Other Genes Between Metastatic and Non-metastatic EL4 Mouse Lymphoma Cells
Q35353329Differential expression of FAK and Pyk2 in metastatic and non-metastatic EL4 lymphoma cell lines
Q58700915The role of CCN4/WISP-1 in the cancerous phenotype

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