| scholarly article | Q13442814 |
| P50 | author | Mensud Hatunic | Q56850905 |
| María Isabel Hernández-Alvarez | Q57236666 | ||
| Deborah Naon | Q60312438 | ||
| P2093 | author name string | Antonio Zorzano | |
| Chiara Chiellini | |||
| Marc Liesa | |||
| Hood Thabit | |||
| Francis Finucane | |||
| John J Nolan | |||
| Nicole Burns | |||
| Syed Shah | |||
| Imad Brema | |||
| P2860 | cites work | Enzyme activity and fiber composition in skeletal muscle of untrained and trained men. | Q55061464 |
| Early-onset type 2 diabetes in obese white subjects is characterised by a marked defect in beta cell insulin secretion, severe insulin resistance and a lack of response to aerobic exercise training | Q60462189 | ||
| Evidence for a mitochondrial regulatory pathway defined by peroxisome proliferator-activated receptor-gamma coactivator-1 alpha, estrogen-related receptor-alpha, and mitofusin 2 | Q83862274 | ||
| Erralpha and Gabpa/b specify PGC-1alpha-dependent oxidative phosphorylation gene expression that is altered in diabetic muscle | Q24564824 | ||
| Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1 | Q24679555 | ||
| Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1 | Q28131760 | ||
| PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes | Q29547229 | ||
| Impaired mitochondrial activity in the insulin-resistant offspring of patients with type 2 diabetes | Q29614548 | ||
| Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes | Q29616567 | ||
| AMP-activated protein kinase-regulated activation of the PGC-1alpha promoter in skeletal muscle cells | Q33381651 | ||
| Mitochondrial fusion is increased by the nuclear coactivator PGC-1beta | Q33381654 | ||
| Type 2 diabetes among North American children and adolescents: an epidemiologic review and a public health perspective | Q33913377 | ||
| Effects of exercise on mitochondrial content and function in aging human skeletal muscle | Q34977262 | ||
| Non-CpG methylation of the PGC-1alpha promoter through DNMT3B controls mitochondrial density. | Q43282402 | ||
| AMP-activated protein kinase (AMPK) is activated in muscle of subjects with type 2 diabetes during exercise | Q43596055 | ||
| Adaptations of skeletal muscle to exercise: rapid increase in the transcriptional coactivator PGC-1. | Q44240302 | ||
| Genes involved in mitochondrial biogenesis/function are induced in response to bilio-pancreatic diversion in morbidly obese individuals with normal glucose tolerance but not in type 2 diabetic patients. | Q45979115 | ||
| The Charcot-Marie-Tooth type 2A gene product, Mfn2, up-regulates fuel oxidation through expression of OXPHOS system | Q46437005 | ||
| Early-onset insulin-resistant diabetes in obese Caucasians has features of typical type 2 diabetes, but 3 decades earlier | Q46458918 | ||
| Insulin-resistant muscle is exercise resistant: evidence for reduced response of nuclear-encoded mitochondrial genes to exercise | Q46817331 | ||
| Effects of physical activity and weight loss on skeletal muscle mitochondria and relationship with glucose control in type 2 diabetes. | Q47286039 | ||
| Characteristics of skeletal muscle mitochondrial biogenesis induced by moderate-intensity exercise and weight loss in obesity | Q47298918 | ||
| Changes induced by physical activity and weight loss in the morphology of intermyofibrillar mitochondria in obese men and women | Q47338109 | ||
| Expression of Mfn2, the Charcot-Marie-Tooth neuropathy type 2A gene, in human skeletal muscle: effects of type 2 diabetes, obesity, weight loss, and the regulatory role of tumor necrosis factor alpha and interleukin-6. | Q47370842 | ||
| P275 | copyright license | Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported | Q19125045 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P433 | issue | 3 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | type 2 diabetes | Q3025883 |
| P304 | page(s) | 645-651 | |
| P577 | publication date | 2009-12-23 | |
| P1433 | published in | Diabetes Care | Q5270111 |
| P1476 | title | Subjects with early-onset type 2 diabetes show defective activation of the skeletal muscle PGC-1{alpha}/Mitofusin-2 regulatory pathway in response to physical activity | |
| P478 | volume | 33 |
| Q42443101 | A form of mitofusin 2 (Mfn2) lacking the transmembrane domains and the COOH-terminal end stimulates metabolism in muscle and liver cells |
| Q41986963 | ATP synthase: from single molecule to human bioenergetics |
| Q37346132 | Acute exercise remodels mitochondrial membrane interactions in mouse skeletal muscle. |
| Q84965732 | Ageing brain abnormalities in young obese patients with type 2 diabetes: a cause for concern |
| Q42176144 | Alternative strategy for Alzheimer's disease: stress response triggers |
| Q47551144 | Axonal transport in a peripheral diabetic neuropathy model: sex-dimorphic features. |
| Q46772385 | Circulating serum irisin levels in obesity and type 2 diabetes mellitus |
| Q37073721 | Clinical significance of mitofusin-2 and its signaling pathways in hepatocellular carcinoma |
| Q37323662 | Coordinated Upregulation of Mitochondrial Biogenesis and Autophagy in Breast Cancer Cells: The Role of Dynamin Related Protein-1 and Implication for Breast Cancer Treatment. |
| Q34901529 | Curcumin restores mitochondrial functions and decreases lipid peroxidation in liver and kidneys of diabetic db/db mice. |
| Q38437166 | Diet impact on mitochondrial bioenergetics and dynamics |
| Q38171358 | Dietary stimulators of the PGC-1 superfamily and mitochondrial biosynthesis in skeletal muscle. A mini-review |
| Q34426000 | Different effects of oleate vs. palmitate on mitochondrial function, apoptosis, and insulin signaling in L6 skeletal muscle cells: role of oxidative stress |
| Q42388840 | Does p49/STRAP, a SRF-binding protein (SRFBP1), modulate cardiac mitochondrial function in aging? |
| Q91801581 | DsbA-L ameliorates high glucose induced tubular damage through maintaining MAM integrity |
| Q47114679 | Early-onset and classical forms of type 2 diabetes show impaired expression of genes involved in muscle branched-chain amino acids metabolism |
| Q43240375 | Effect of colon cancer and surgical resection on skeletal muscle mitochondrial enzyme activity in colon cancer patients: a pilot study |
| Q33669722 | Effects of high-intensity interval training and moderate-intensity continuous training on glycaemic control and skeletal muscle mitochondrial function in db/db mice. |
| Q35620492 | Gene and MicroRNA Expression Responses to Exercise; Relationship with Insulin Sensitivity |
| Q40901271 | Habitual physical activity is associated with circulating irisin in healthy controls but not in subjects with diabetes mellitus type 2. |
| Q27005955 | Heart failure and mitochondrial dysfunction: the role of mitochondrial fission/fusion abnormalities and new therapeutic strategies |
| Q64094437 | Higher Baseline Serum Irisin Decreases Risk for Body Mass Index Increment in Chinese Populations: A 3.2-Year Cohort Study |
| Q36200582 | IL-6 regulation on skeletal muscle mitochondrial remodeling during cancer cachexia in the ApcMin/+ mouse. |
| Q27313507 | Impaired mitochondrial dynamics and bioenergetics in diabetic skeletal muscle |
| Q34429185 | Impaired overload-induced hypertrophy is associated with diminished mTOR signaling in insulin-resistant skeletal muscle of the obese Zucker rat |
| Q64882905 | Inhibition of Mitofusin-2 Promotes Cardiac Fibroblast Activation via the PERK/ATF4 Pathway and Reactive Oxygen Species. |
| Q35569606 | Insight into the impact of dietary saturated fat on tissue-specific cellular processes underlying obesity-related diseases |
| Q37341971 | Insulin sensitivity and metabolic flexibility following exercise training among different obese insulin-resistant phenotypes. |
| Q55391745 | Intact regulation of muscle expression and circulating levels of myokines in response to exercise in patients with type 2 diabetes. |
| Q38846360 | Intersection of mitochondrial fission and fusion machinery with apoptotic pathways: Role of Mcl-1. |
| Q34974500 | Is there a metabolic program in the skeletal muscle of obese individuals? |
| Q85486168 | Leptin-induced mitochondrial fusion mediates hepatic lipid accumulation |
| Q33816920 | Loss of Pgc-1α expression in aging mouse muscle potentiates glucose intolerance and systemic inflammation |
| Q51650396 | Mechanical ventilation triggers abnormal mitochondrial dynamics and morphology in the diaphragm. |
| Q36349560 | Mechanism of Activation-Induced Downregulation of Mitofusin 2 in Human Peripheral Blood T Cells |
| Q92195093 | Mechanisms of obesity-induced metabolic and vascular dysfunctions |
| Q33749007 | Mfn2 is critical for brown adipose tissue thermogenic function |
| Q49907062 | MiRNA-binding site variants of type 2 diabetes candidate loci predispose to gestational diabetes mellitus in Chinese Han women. |
| Q37054672 | Mild fasting hyperglycemia shifts fuel reliance toward fat during exercise in adults with impaired glucose tolerance |
| Q26770420 | Mitochondrial Quality Control and Muscle Mass Maintenance |
| Q38189524 | Mitochondrial alteration in type 2 diabetes and obesity: an epigenetic link. |
| Q38247061 | Mitochondrial dynamics in the central regulation of metabolism |
| Q35607344 | Mitochondrial dysregulation in the pathogenesis of diabetes: potential for mitochondrial biogenesis-mediated interventions. |
| Q39090640 | Mitochondrial fission mediates ceramide-induced metabolic disruption in skeletal muscle. |
| Q39089107 | Mitochondrial fragmentation impairs insulin-dependent glucose uptake by modulating Akt activity through mitochondrial Ca2+ uptake. |
| Q28083322 | Mitochondrial metabolism and the control of vascular smooth muscle cell proliferation |
| Q36530942 | Mitochondrial morphology, topology, and membrane interactions in skeletal muscle: a quantitative three-dimensional electron microscopy study |
| Q35887283 | Mitofusin 2 (Mfn2) links mitochondrial and endoplasmic reticulum function with insulin signaling and is essential for normal glucose homeostasis |
| Q38974494 | Mitofusin 2 deficiency leads to oxidative stress that contributes to insulin resistance in rat skeletal muscle cells. |
| Q37339111 | Mitofusin 2 in POMC neurons connects ER stress with leptin resistance and energy imbalance. |
| Q36699198 | Mitofusin-2 ameliorates high-fat diet-induced insulin resistance in liver of rats |
| Q39026689 | Mitofusin-2 over-expresses and leads to dysregulation of cell cycle and cell invasion in lung adenocarcinoma |
| Q37407291 | Mitofusin-2 prevents skeletal muscle wasting in cancer cachexia |
| Q34906459 | Mitophagy: therapeutic potentials for liver disease and beyond |
| Q38572485 | Molecular insight and pharmacological approaches targeting mitochondrial dynamics in skeletal muscle during obesity |
| Q34598672 | Muscle oxidative capacity during IL-6-dependent cancer cachexia. |
| Q36126187 | Relationships between mitochondrial content and bioenergetics with obesity, body composition and fat distribution in healthy older adults |
| Q37949231 | Resistance to type 2 diabetes mellitus: a matter of hormesis? |
| Q55266104 | Resveratrol Improves Muscle Atrophy by Modulating Mitochondrial Quality Control in STZ-Induced Diabetic Mice. |
| Q90661070 | Role of mitochondrial quality control in the pathogenesis of nonalcoholic fatty liver disease |
| Q37405224 | Role of mitofusin 2 (Mfn2) in controlling cellular proliferation |
| Q91940246 | Role of surface ectoderm-specific mitofusin 2 in the corneal morphologic development of mice |
| Q99609879 | Serum Irisin Levels, Endothelial Dysfunction, and Inflammation in Pediatric Patients with Type 2 Diabetes Mellitus and Metabolic Syndrome |
| Q58553026 | Shenqi Fuzheng Injection Reverses Cisplatin Resistance through Mitofusin-2-Mediated Cell Cycle Arrest and Apoptosis in A549/DDP Cells |
| Q34925298 | Short term exercise induces PGC-1α, ameliorates inflammation and increases mitochondrial membrane proteins but fails to increase respiratory enzymes in aging diabetic hearts |
| Q26772781 | Skeletal Muscle Mitochondrial Bioenergetics and Morphology in High Fat Diet Induced Obesity and Insulin Resistance: Focus on Dietary Fat Source |
| Q36603044 | Skeletal intramyocellular lipid metabolism and insulin resistance |
| Q45071737 | Skeletal muscle autophagy and mitophagy in endurance-trained runners before and after a high-fat meal. |
| Q38905640 | Skeletal muscle mitochondria as a target to prevent or treat type 2 diabetes mellitus |
| Q38543545 | Targeting skeletal muscle mitochondria to prevent type 2 diabetes in youth |
| Q36473802 | The Association of Mitofusion-2 Gene Polymorphisms with Susceptibility of Essential Hypertension in Northern Han Chinese Population |
| Q36901945 | The emerging role of skeletal muscle oxidative metabolism as a biological target and cellular regulator of cancer-induced muscle wasting |
| Q37815475 | The interplay between mitochondrial dynamics and mitophagy |
| Q37665625 | Therapeutic potential of pterostilbene against pancreatic beta-cell apoptosis mediated through Nrf2. |
| Q38988240 | Tumour necrosis factor-α promotes liver ischaemia-reperfusion injury through the PGC-1α/Mfn2 pathway |
| Q50065521 | Turning Over the Hourglass |
| Q42046906 | mRNA PGC-1α levels in blood samples reliably correlates with its myocardial expression: study in patients undergoing cardiac surgery. |
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