Young little mice express a premature cardiovascular aging phenotype

scientific article

Young little mice express a premature cardiovascular aging phenotype is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1093/GERONA/GLT055
P932PMC publication ID4038241
P698PubMed publication ID23682160
P5875ResearchGate publication ID236916629

P2093author name stringMark L Entman
Craig J Hartley
George E Taffet
Anilkumar K Reddy
Gretchen Darlington
Thuy T Pham
P2860cites workInherited Ateliotic Dwarfism in Mice: Characteristics of the mutation, little, on Chromosome 6Q28507826
Growth hormone deficiency in 'little' mice results in aberrant body composition, reduced insulin-like growth factor-I and insulin-like growth factor-binding protein-3 (IGFBP-3), but does not affect IGFBP-2, -1 or -4Q28508126
Lifespan extension and delayed immune and collagen aging in mutant mice with defects in growth hormone productionQ28511652
GHRH receptor of little mice contains a missense mutation in the extracellular domain that disrupts receptor functionQ28512102
Alterations in xenobiotic metabolism in the long-lived Little miceQ33809704
Genes that prolong life: relationships of growth hormone and growth to aging and life spanQ34327394
Phenotype and genetic analysis of a syndrome caused by an inactivating mutation in the growth hormone-releasing hormone receptor: Dwarfism of SindhQ34479974
Genetic mouse models of extended lifespanQ34544303
A critical analysis of the role of growth hormone and IGF-1 in aging and lifespan.Q34666727
Prevalence and demographic features of childhood growth hormone deficiency in Belgium during the period 1986-2001.Q35833863
The emerging role of IGF-1 deficiency in cardiovascular aging: recent advancesQ35947431
Aging, atherosclerosis, and IGF-1Q35947440
Diverse roles of growth hormone and insulin-like growth factor-1 in mammalian aging: progress and controversies.Q35947444
Growth hormone, inflammation and agingQ36159113
Longevity is associated with increased vascular resistance to high glucose-induced oxidative stress and inflammatory gene expression in Peromyscus leucopusQ37162511
Clinical achievements of impedance analysisQ37293293
Cardiac function in young and old Little miceQ37407734
Body composition in hypopituitary dwarfs before and during human growth hormone therapyQ40236222
Regional wave travel and reflections along the human aorta: a study with six simultaneous micromanometric pressuresQ41506392
Is growth hormone bad for your heart? Cardiovascular impact of GH deficiency and of acromegalyQ41656053
The oxidative stress theory of aging: embattled or invincible? Insights from non-traditional model organismsQ42129059
Relationships between serum IGF1 levels, blood pressure, and glucose tolerance: an observational, exploratory study in 404 subjectsQ44490881
Detection of premature atherosclerosis by high-resolution ultrasonography in symptom-free hypopituitary adultsQ44934235
Insulin-like growth factor-1 deficiency determines increased intima-media thickness at common carotid arteries in adult patients with growth hormone deficiencyQ45050050
Gene expression profile of long-lived Ames dwarf mice and Little miceQ45166257
Low thyroid function leads to cardiac atrophy with chamber dilatation, impaired myocardial blood flow, loss of arterioles, and severe systolic dysfunctionQ46795007
Big mice die young: early life body weight predicts longevity in genetically heterogeneous mice.Q47446794
Endothelial dysfunction in hypopituitary adults with growth hormone deficiencyQ49075956
Noninvasive determination of pulse-wave velocity in mice.Q51539464
Growth hormone receptor deficiency in mice results in reduced systolic blood pressure and plasma renin, increased aortic eNOS expression, and altered cardiovascular structure and function.Q51769556
Pulsed Doppler signal processing for use in mice: applications.Q51961959
Hypertension and cardiac hypertrophy in growth hormone-deficient rats.Q52215496
Obesity: age-associated weight gain and the development of disease. An interview with Nir Barzilai. Interview by Marc E. Weksler.Q52380524
Adrenoceptor-mediated cardiac and vascular responses in genetically growth hormone-deficient ratsQ70461681
Aortic Pulse-Wave Velocity in Chickens and DucksQ71071692
Aortic distensibility in growth hormone deficient adultsQ72209360
Vascular Ca overload produced by vitamin D3 plus nicotine diminishes arterial distensibility in ratsQ72324088
Echocardiographic assessment of cardiac morphology and function in mutant dwarf ratsQ73102961
Observational study in adult hypopituitary patients with untreated growth hormone deficiency (ODA study). Socio-economic impact and health status. Collaborative ODA (Observational GH Deficiency in Adults) GroupQ73216241
Measurement of aortic input impedance in mice: effects of age on aortic stiffnessQ73454919
Evaluation and characterization of congenital hypothyroidism in rdw dwarf ratsQ74630982
Insulin action in growth hormone-deficient and age-matched control rats: effect of growth hormone treatmentQ77686093
The effects of 10 years of recombinant human growth hormone (GH) in adult GH-deficient patientsQ78114977
Obese adults with primary growth hormone resistance (Laron Syndrome) have normal endothelial functionQ79826450
Diet and agingQ81743360
Mice severely deficient in growth hormone have normal hematopoiesisQ81865174
Thyroid hormone and the cardiovascular systemQ83736142
P433issue2
P407language of work or nameEnglishQ1860
P304page(s)152-159
P577publication date2013-05-16
P1433published inThe Journals of GerontologyQ7743644
P1476titleYoung little mice express a premature cardiovascular aging phenotype
P478volume69

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cites work (P2860)
Q64893979IGF-1 Deficiency Promotes Pathological Remodeling of Cerebral Arteries: A Potential Mechanism Contributing to the Pathogenesis of Intracerebral Hemorrhages in Aging.
Q41444071IGF-1 deficiency in a critical period early in life influences the vascular aging phenotype in mice by altering miRNA-mediated post-transcriptional gene regulation: implications for the developmental origins of health and disease hypothesis.
Q36231819SRC-1 Regulates Blood Pressure and Aortic Stiffness in Female Mice

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