Statin pharmacogenomics: pursuing biomarkers for predicting clinical outcomes

scientific article

Statin pharmacogenomics: pursuing biomarkers for predicting clinical outcomes is …
instance of (P31):
scholarly articleQ13442814

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P932PMC publication ID4039562
P698PubMed publication ID23911231

P2093author name stringDamiano Baldassarre
Joseph P Kitzmiller
Philip F Binkley
Adam M Suhy
Katherine Hartmann
Saurabh R Pandey
P2860cites workNewly identified loci that influence lipid concentrations and risk of coronary artery diseaseQ28264535
High plasma pravastatin concentrations are associated with single nucleotide polymorphisms and haplotypes of organic anion transporting polypeptide-C (OATP-C, SLCO1B1)Q28269517
Cholesteryl Ester Transfer Protein (CETP) polymorphisms affect mRNA splicing, HDL levels, and sex-dependent cardiovascular riskQ28731522
SLCO1B1 variants and statin-induced myopathy--a genomewide studyQ29619028
Growing epidemic of coronary heart disease in low- and middle-income countriesQ33828135
The use of phenome-wide association studies (PheWAS) for exploration of novel genotype-phenotype relationships and pleiotropy discoveryQ35049307
Intronic polymorphism in CYP3A4 affects hepatic expression and response to statin drugsQ35642257
Autoantibodies against 3-hydroxy-3-methylglutaryl-coenzyme A reductase in patients with statin-associated autoimmune myopathyQ35909737
Common nonsynonymous substitutions in SLCO1B1 predispose to statin intolerance in routinely treated individuals with type 2 diabetes: a go-DARTS studyQ35964012
Genetic variation at the LDL receptor and HMG-CoA reductase gene loci, lipid levels, statin response, and cardiovascular disease incidence in PROSPER.Q36045787
Antibody levels correlate with creatine kinase levels and strength in anti-3-hydroxy-3-methylglutaryl-coenzyme A reductase-associated autoimmune myopathy.Q36434543
Effect of cytochrome P450 3A5 genotype on atorvastatin pharmacokinetics and its interaction with clarithromycin.Q37017426
Lipid management in the prevention of stroke: review and updated meta-analysis of statins for stroke preventionQ37449898
Lack of effect of genetic polymorphisms of SLCO1B1 on the lipid-lowering response to pitavastatin in Chinese patientsQ37728163
Differential effect of the rs4149056 variant in SLCO1B1 on myopathy associated with simvastatin and atorvastatin.Q42757090
Pharmacogenetic interactions between ABCB1 and SLCO1B1 tagging SNPs and the effectiveness of statins in the prevention of myocardial infarctionQ42936467
Comprehensive whole-genome and candidate gene analysis for response to statin therapy in the Treating to New Targets (TNT) cohortQ43209469
Novel CYP3A4 intron 6 single nucleotide polymorphism is associated with simvastatin-mediated cholesterol reduction in the Rotterdam StudyQ44077542
Pharmacogenetic study of statin therapy and cholesterol reductionQ44938097
Lipid-lowering response to statins is affected by CYP3A5 polymorphismQ45000633
Cholesteryl ester transfer protein TaqIB variant, high-density lipoprotein cholesterol levels, cardiovascular risk, and efficacy of pravastatin treatment: individual patient meta-analysis of 13,677 subjects.Q45227730
ABCB1 haplotypes differentially affect the pharmacokinetics of the acid and lactone forms of simvastatin and atorvastatin.Q46111557
CETP genotype predicts increased mortality in statin-treated men with proven cardiovascular disease: an adverse pharmacogenetic interactionQ46289075
A paucimorphic variant in the HMG-CoA reductase gene is associated with lipid-lowering response to statin treatment in diabetes: a GoDARTS study.Q46348510
CYP3A53A allele is associated with reduced lowering-lipid response to atorvastatin in individuals with hypercholesterolemiaQ46410827
Variation in the 3-hydroxyl-3-methylglutaryl coenzyme a reductase gene is associated with racial differences in low-density lipoprotein cholesterol response to simvastatin treatmentQ46520652
An association study of 43 SNPs in 16 candidate genes with atorvastatin responseQ46653214
The role of common variants of ABCB1, CYP3A4, and CYP3A5 genes in lipid-lowering efficacy and safety of simvastatin treatmentQ46830670
Effect of polymorphic CYP3A5 genotype on the single-dose simvastatin pharmacokinetics in healthy subjects.Q53581879
Regulation of plasma HDL cholesterol and subfraction distribution by genetic and environmental factors. Associations between the TaqI B RFLP in the CETP gene and smoking and obesity.Q54103484
Genetic analysis of fluvastatin response and dyslipidemia in renal transplant recipientsQ57750555
The Role of a Common Variant of the Cholesteryl Ester Transfer Protein Gene in the Progression of Coronary AtherosclerosisQ60233014
Contribution of cytochrome P450 3A4 and 3A5 to the metabolism of atorvastatinQ94705921
Multidrug resistance polypeptide 1 (MDR1, ABCB1) variant 3435C>T affects mRNA stabilityQ95805177
P433issue86
P921main subjectbiomarkerQ864574
pharmacogenomicsQ1152227
P304page(s)45-51
P577publication date2013-08-01
P1433published inDiscovery MedicineQ5281940
P1476titleStatin pharmacogenomics: pursuing biomarkers for predicting clinical outcomes
P478volume16

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cites work (P2860)
Q35799847ABCB1 C3435T polymorphism and the lipid-lowering response in hypercholesterolemic patients on statins: a meta-analysis
Q30490270Economic Evaluation of a Pharmacogenomics Test for Statin-Induced Myopathy in Cardiovascular High-Risk Patients Initiating a Statin.
Q39514336Frequency distribution of polymorphisms of CYP2C19, CYP2C9, VKORC1 and SLCO1B1 genes in the Yakut population
Q57285996KIF6 gene as a pharmacogenetic marker for lipid-lowering effect in statin treatment
Q26771550Lipids, blood pressure and kidney update 2015
Q63443841Sub-optimal cholesterol response to initiation of statins and future risk of cardiovascular disease

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