High density DNA array analysis reveals distinct genomic profiles in a subset of gastrointestinal stromal tumors

scientific article

High density DNA array analysis reveals distinct genomic profiles in a subset of gastrointestinal stromal tumors is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/GCC.20689
P932PMC publication ID2830286
P698PubMed publication ID19585585
P5875ResearchGate publication ID26654978

P50authorMargaret von MehrenQ66809438
Andrew K GodwinQ89896596
P2093author name stringDavid Riddell
Kathy Q Cai
Joseph R Testa
Jianming Pei
Lori Rink
Martin G Belinsky
Burton L Eisenberg
Lisa A Vanderveer
Erin Merkel
Chi Tarn
Yuliya V Skorobogatko
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DNA sequence copy number changes in gastrointestinal stromal tumors: tumor progression and prognostic significanceQ74088062
Interstitial cells of Cajal as precursors of gastrointestinal stromal tumorsQ77311208
An oncogenetic tree model in gastrointestinal stromal tumours (GISTs) identifies different pathways of cytogenetic evolution with prognostic implicationsQ79568269
Array comparative genomic hybridization reveals distinct DNA copy number differences between gastrointestinal stromal tumors and leiomyosarcomasQ80283497
Early effects of imatinib mesylate on the expression of insulin-like growth factor binding protein-3 and positron emission tomography in patients with gastrointestinal stromal tumorQ80298660
Insulin-like growth factor (IGF) 1 and 2 help to predict disease outcome in GIST patientsQ80971360
Pediatric KIT wild-type and platelet-derived growth factor receptor alpha-wild-type gastrointestinal stromal tumors share KIT activation but not mechanisms of genetic progression with adult gastrointestinal stromal tumorsQ81381492
Loss of p16 protein defines high-risk patients with gastrointestinal stromal tumors: a tissue microarray studyQ81383348
KIT mutations are common in incidental gastrointestinal stromal tumors one centimeter or less in sizeQ27824783
Kinase mutations and imatinib response in patients with metastatic gastrointestinal stromal tumorQ27824804
Gain-of-Function Mutations of c- kit in Human Gastrointestinal Stromal TumorsQ28118852
Gastrointestinal stromal tumors: review on morphology, molecular pathology, prognosis, and differential diagnosisQ28272917
Efficacy and safety of imatinib mesylate in advanced gastrointestinal stromal tumorsQ29618610
Clinical and molecular characteristics of gastrointestinal stromal tumors in the pediatric and young adult populationQ33654872
Novel V600E BRAF mutations in imatinib-naive and imatinib-resistant gastrointestinal stromal tumorsQ33988695
PDGFRA activating mutations in gastrointestinal stromal tumors.Q34169772
Use of c-KIT/PDGFRA mutational analysis to predict the clinical response to imatinib in patients with advanced gastrointestinal stromal tumours entered on phase I and II studies of the EORTC Soft Tissue and Bone Sarcoma GroupQ34546186
Gastrointestinal stromal tumors of the stomach: a clinicopathologic, immunohistochemical, and molecular genetic study of 1765 cases with long-term follow-upQ34553656
Array comparative genomic hybridization analysis of chromosomal imbalances and their target genes in gastrointestinal stromal tumorsQ34576648
Diagnosis of gastrointestinal stromal tumors: a consensus approachQ34697685
Gastrointestinal pacemaker cell tumor (GIPACT): gastrointestinal stromal tumors show phenotypic characteristics of the interstitial cells of CajalQ34747216
Improved detection of KIT exon 11 duplications in formalin-fixed, paraffin-embedded gastrointestinal stromal tumorsQ35789573
Biology of gastrointestinal stromal tumors.Q35886298
Clinical and molecular characteristics of pediatric gastrointestinal stromal tumors (GISTs).Q36082596
Gastrointestinal stromal tumors in children and young adults: a clinicopathologic, molecular, and genomic study of 15 cases and review of the literatureQ36101673
Gastrointestinal stromal tumors of the stomach in children and young adults: a clinicopathologic, immunohistochemical, and molecular genetic study of 44 cases with long-term follow-up and review of the literatureQ36256478
Immunohistochemical expression of p16INK4A, Ki-67, and Mcm2 proteins in gastrointestinal stromal tumors: prognostic implications and correlations with risk stratification of NIH consensus criteriaQ36609605
Insulin-like growth factor 1 receptor is a potential therapeutic target for gastrointestinal stromal tumorsQ36751533
p16 expression differentiates high-risk gastrointestinal stromal tumor and predicts poor outcomeQ36897784
Molecular pathobiology of gastrointestinal stromal sarcomas.Q37014848
Phase II trial of neoadjuvant/adjuvant imatinib mesylate (IM) for advanced primary and metastatic/recurrent operable gastrointestinal stromal tumor (GIST): early results of RTOG 0132/ACRIN 6665.Q37023177
Therapeutic strategies for targeting BRAF in human cancerQ37161265
Molecular characterization of pediatric gastrointestinal stromal tumors.Q37247100
The insulin-like growth factor system as a potential therapeutic target in gastrointestinal stromal tumorsQ37279733
Safety and efficacy of imatinib (STI571) in metastatic gastrointestinal stromal tumours: a phase I studyQ43797374
KIT activation is a ubiquitous feature of gastrointestinal stromal tumorsQ43806543
Diagnostic and prognostic markers for gastrointestinal stromal tumors in NorwayQ45023853
Analysis of KIT mutations in sporadic and familial gastrointestinal stromal tumors: therapeutic implications through protein modelingQ46493673
Altered expression of cell cycle regulatory proteins in gastrointestinal stromal tumors: markers with potential prognostic implicationsQ53620654
P433issue10
P304page(s)886-896
P577publication date2009-10-01
P1433published inGenes, Chromosomes and CancerQ5532697
P1476titleHigh density DNA array analysis reveals distinct genomic profiles in a subset of gastrointestinal stromal tumors
P478volume48

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cites work (P2860)
Q43465485A molecular portrait of gastrointestinal stromal tumors: an integrative analysis of gene expression profiling and high-resolution genomic copy number
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Q38119931An overview on molecular biology of KIT/PDGFRA wild type (WT) gastrointestinal stromal tumours (GIST).
Q39148688Bench to Bedside and Back Again: Personalizing Treatment for Patients with GIST
Q36125976Beyond standard therapy: drugs under investigation for the treatment of gastrointestinal stromal tumor
Q35562510Copy-neutral loss of heterozygosity and chromosome gains and losses are frequent in gastrointestinal stromal tumors.
Q37001194Drug Repurposing for Gastrointestinal Stromal Tumor
Q34289180Drug repurposing identifies a synergistic combination therapy with imatinib mesylate for gastrointestinal stromal tumor
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Q37716749Tumor-derived exosomes: A message delivery system for tumor progression.

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