Vitamin D prevents endothelial progenitor cell dysfunction induced by sera from women with preeclampsia or conditioned media from hypoxic placenta

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Vitamin D prevents endothelial progenitor cell dysfunction induced by sera from women with preeclampsia or conditioned media from hypoxic placenta is …
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scholarly articleQ13442814

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P819ADS bibcode2014PLoSO...998527B
P356DOI10.1371/JOURNAL.PONE.0098527
P932PMC publication ID4041729
P698PubMed publication ID24887145
P5875ResearchGate publication ID262787999

P50authorConstantin von KaisenbergQ40928319
Frauke von Versen-HöynckQ56501716
Magdalena GrundmannQ89287798
Lars BrodowskiQ89288205
Carl A HubelQ89289297
P2093author name stringAshley C Myerski
Jennifer Burlakov
P2860cites workThe 2011 report on dietary reference intakes for calcium and vitamin D from the Institute of Medicine: what clinicians need to knowQ22306208
Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsiaQ29615916
Uterine vasculature remodeling in human pregnancy involves functional macrochimerism by endothelial colony forming cells of fetal origin.Q30555841
Maternal endothelial progenitor colony-forming units with macrophage characteristics are reduced in preeclampsiaQ33698023
Preeclampsia: what we know and what we do not knowQ33858363
Beyond oxygen: complex regulation and activity of hypoxia inducible factors in pregnancy.Q33894600
Maternal circulating CD34+VEGFR-2+ and CD133+VEGFR-2+ progenitor cells increase during normal pregnancy but are reduced in women with preeclampsiaQ33945532
Latest advances in understanding preeclampsiaQ34425288
Identification and regulation of 1,25-dihydroxyvitamin D3 receptor activity and biosynthesis of 1,25-dihydroxyvitamin D3. Studies in cultured bovine aortic endothelial cells and human dermal capillariesQ34574684
Maternal vitamin D deficiency increases the risk of preeclampsiaQ34579840
Endothelial progenitor cells for vascular regenerationQ34619706
Maternal vitamin D and fetal growth in early-onset severe preeclampsiaQ35106064
Vitamin D and placental-decidual functionQ35818765
Human placental explants in culture: approaches and assessments.Q36159671
Vitamin D improves the angiogenic properties of endothelial progenitor cells.Q36382400
Preeclampsia--a pressing problem: an executive summary of a National Institute of Child Health and Human Development workshopQ36981099
Human placental adenosine receptor expression is elevated in preeclampsia and hypoxia increases expression of the A2A receptor.Q37172666
Oxygen, the Janus gas; its effects on human placental development and functionQ37272104
Uric acid attenuates trophoblast invasion and integration into endothelial cell monolayersQ37298028
Endothelial colony-forming cells derived from pregnancies complicated by intrauterine growth restriction are fewer and have reduced vasculogenic capacityQ37361789
Role of vitamin D receptor in the antiproliferative effects of calcitriol in tumor-derived endothelial cells and tumor angiogenesis in vivoQ37363014
Pre-eclampsia and cardiovascular diseaseQ37615825
Endothelial progenitor cells: their potential in the placental vasculature and related complicationsQ37633745
Cardiovascular risk factors in children and young adults born to preeclamptic pregnancies: a systematic reviewQ38012024
Maternal vitamin D status and risk of pre-eclampsia: a systematic review and meta-analysisQ38115673
Endothelial colony-forming cells show a mature transcriptional response to shear stressQ39684920
Expression and activity of vitamin D receptor in the human placenta and in choriocarcinoma BeWo and JEG-3 cell linesQ39897223
1,25-dihydroxyvitamin D3 regulates VEGF production through a vitamin D response element in the VEGF promoterQ39932703
Changes in the metabolic footprint of placental explant-conditioned culture medium identifies metabolic disturbances related to hypoxia and pre-eclampsia.Q43272404
Does vitamin D supplementation in infancy reduce the risk of pre-eclampsia?Q44428753
Dietary vitamin D restriction in pregnant female mice is associated with maternal hypertension and altered placental and fetal development.Q44949281
Calcitriol inhibits TNF-alpha-induced inflammatory cytokines in human trophoblasts.Q45980113
In vitro hyperglycemia or a diabetic intrauterine environment reduces neonatal endothelial colony-forming cell numbers and function.Q46845293
Longitudinal changes in maternal serum 1,25-dihydroxyvitamin D and insulin like growth factor I levels in pregnant women who developed preeclampsia: comparison with normotensive pregnant womenQ47266952
Evidence of endothelial dysfunction in preeclampsia: decreased endothelial nitric oxide synthase expression is associated with increased cell permeability in endothelial cells from preeclampsiaQ47889158
Elevated placental soluble vascular endothelial growth factor receptor-1 inhibits angiogenesis in preeclampsiaQ47915288
Vitamin D insufficiency is associated with impaired vascular endothelial and smooth muscle function and hypertension in young rats.Q51431469
Effects of oxygen on cell turnover and expression of regulators of apoptosis in human placental trophoblast.Q53509352
Effects of 25-hydroxyvitamin D3 and 1,25-dihydroxyvitamin D3 on cytokine production by human decidual cells.Q53600837
1,25-Dihydroxyvitamin D3 stimulates vascular smooth muscle cell proliferation through a VEGF-mediated pathway.Q54612212
Formation of Syncytial Knots is Increased by Hyperoxia, Hypoxia and Reactive Oxygen SpeciesQ59366262
Vitamin D Supplementation and Reduced Risk of Preeclampsia in Nulliparous WomenQ62565327
Endothelial cell proliferation is suppressed by plasma but not serum from women with preeclampsiaQ71064218
Human placental syncytiotrophoblast microvillous membranes impair maternal vascular endothelial functionQ73154757
AT(1) receptor agonistic antibodies from preeclamptic patients cause vascular cells to express tissue factorQ73815485
1 alpha,25-dihydroxyvitamin D(3) inhibits angiogenesis in vitro and in vivoQ74113984
Strikingly different angiogenic properties of endothelial progenitor cell subpopulations: insights from a novel human angiogenesis assayQ80665054
Calcitriol inhibits interleukin-10 expression in cultured human trophoblasts under normal and inflammatory conditionsQ83061305
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectpre-eclampsiaQ61335
hypoxiaQ105688
endotheliumQ111140
vitamin DQ175621
P304page(s)e98527
P577publication date2014-06-02
P1433published inPLOS OneQ564954
P1476titleVitamin D prevents endothelial progenitor cell dysfunction induced by sera from women with preeclampsia or conditioned media from hypoxic placenta
P478volume9

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cites work (P2860)
Q92482726Evaluation of vitamin D status, parathyroid hormone, and calcium among Iranian pregnant women with preeclampsia: A case-control study
Q36618978ILs-3, 6 and 11 increase, but ILs-10 and 24 decrease stemness of human prostate cancer cells in vitro
Q33719143Impaired functional capacity of fetal endothelial cells in preeclampsia
Q40487285Low maternal 25-hydroxyvitamin D concentration increases the risk of severe and mild preeclampsia
Q37673219Maternal Vitamin D Status in the Late Second Trimester and the Risk of Severe Preeclampsia in Southeastern China
Q64074927Preeclampsia-Associated Alteration of DNA Methylation in Fetal Endothelial Progenitor Cells
Q33909763The role of vitamin D in pre-eclampsia: a systematic review
Q26801481Vitamin D and Inflammatory Cytokines in Healthy and Preeclamptic Pregnancies

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