Cell biology of the osteoclast

scientific article

Cell biology of the osteoclast is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1016/S0301-472X(99)00061-2
P698PubMed publication ID10428500

P2093author name stringRoodman GD
P2860cites workMolecular cloning of a cDNA encoding interleukin 11, a stromal cell-derived lymphopoietic and hematopoietic cytokineQ24298662
Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activationQ24311588
Osteoprotegerin: a novel secreted protein involved in the regulation of bone densityQ24313918
Expression of two human skeletal calcitonin receptor isoforms cloned from a giant cell tumor of bone. The first intracellular domain modulates ligand binding and signal transductionQ24320379
Soluble interleukin-6 receptor triggers osteoclast formation by interleukin 6Q24563585
Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKLQ24682139
Carbonic anhydrase II deficiency in 12 families with the autosomal recessive syndrome of osteopetrosis with renal tubular acidosis and cerebral calcificationQ28307228
Expression of the calcitonin receptor in bone marrow cell cultures and in bone: a specific marker of the differentiated osteoclast that is regulated by calcitoninQ28511417
Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in miceQ29547898
Transforming growth factor beta inhibits formation of osteoclast-like cells in long-term human marrow culturesQ33636797
Inducible production of nitric oxide in osteoblast-like cells and in fetal mouse bone explants is associated with suppression of osteoclastic bone resorptionQ34138159
Interleukin-11: a new cytokine critical for osteoclast developmentQ34138407
Downregulation of calcitonin receptor mRNA expression by calcitonin during human osteoclast-like cell differentiationQ34193938
Interleukin-6 enhances hypercalcemia and bone resorption mediated by parathyroid hormone-related protein in vivoQ34224284
Osteoclastic bone resorption by a polarized vacuolar proton pumpQ34441726
Identity of osteoclastogenesis inhibitory factor (OCIF) and osteoprotegerin (OPG): a mechanism by which OPG/OCIF inhibits osteoclastogenesis in vitroQ34459310
Bidirectional regulation of osteoclast function by nitric oxide synthase isoformsQ34520984
Recombinant human transforming growth factor-alpha stimulates the formation of osteoclast-like cells in long-term human marrow culturesQ34540942
Modulation of type beta transforming growth factor activity in bone cultures by osteotropic hormonesQ34610078
Rescue of osteoclast function by transgenic expression of kinase-deficient Src in src-/- mutant miceQ35194925
Human giant cell tumors of the bone (osteoclastomas) are estrogen target cellsQ35412006
Interleukin 6. A potential autocrine/paracrine factor in Paget's disease of boneQ35595884
Requirement of pp60c-src expression for osteoclasts to form ruffled borders and resorb bone in miceQ35607627
Transforming growth factor-beta 1 as a signal for induction of cell death by apoptosisQ35975984
Identification and characterization of osteoclast-like cells and their progenitors in cultures of feline marrow mononuclear cellsQ36210851
Essential role of macrophage colony-stimulating factor in the osteoclast differentiation supported by stromal cellsQ36230062
Substrate recognition by osteoclast precursors induces C-src/microtubule association.Q36274033
Osteopetrosis in Src-deficient mice is due to an autonomous defect of osteoclasts.Q36301037
In vitro formation of osteoclasts from long-term cultures of bone marrow mononuclear phagocytesQ36347206
Osteoblasts mediate interleukin 1 stimulation of bone resorption by rat osteoclastsQ36352137
Osteoblastic cells mediate osteoclastic responsiveness to parathyroid hormoneQ36458074
Characterization of the osteoclast vacuolar H+-ATPase B-subunitQ36690409
New resorption assay with mouse osteoclast-like multinucleated cells formed in vitroQ36697460
Osteoporosis induced in mice by overproduction of interleukin 4.Q36716814
Interleukin 18 inhibits osteoclast formation via T cell production of granulocyte macrophage colony-stimulating factor.Q37377903
Immortalization of osteoclast precursors by targeting Bcl -XL and Simian virus 40 large T antigen to the osteoclast lineage in transgenic miceQ37387048
Avian osteoclasts as estrogen target cellsQ37557847
1,25-Dihydroxyvitamin D3 causes formation of multinucleated cells with several osteoclast characteristics in cultures of primate marrowQ37557858
Homologous regulation of the calcitonin receptor in mouse osteoclast-like cells and human breast cancer T47D cellsQ38294720
Calcitonin receptor isoforms in mouse and rat osteoclastsQ38300547
c-Cbl is downstream of c-Src in a signalling pathway necessary for bone resorption.Q38352423
Osteoclast differentiation factor mediates an essential signal for bone resorption induced by 1 alpha,25-dihydroxyvitamin D3, prostaglandin E2, or parathyroid hormone in the microenvironment of boneQ39116021
Severe osteoporosis in mice lacking osteoclastogenesis inhibitory factor/osteoprotegerinQ39116155
Evidence that tumor necrosis factor plays a pathogenetic role in the paraneoplastic syndromes of cachexia, hypercalcemia, and leukocytosis in a human tumor in nude miceQ40512172
Generation of mouse osteoclastogenic cell lines immortalized with SV40 large T antigenQ41026072
Inhibitory and stimulatory effects of prostaglandins on osteoclast differentiationQ41141652
Role of osteoblasts in hormonal control of bone resorption—A hypothesisQ41551873
Macrophage colony-stimulating factor stimulates survival and chemotactic behavior in isolated osteoclastsQ41773356
Interleukin-6 is produced by bone and modulated by parathyroid hormoneQ43600464
Carbonic anhydrase and bone remodeling: sulfonamide inhibition of bone resorption in organ cultureQ44036900
Formation of multinucleated cells that respond to osteotropic hormones in long term human bone marrow culturesQ44145438
Humoral and ionic regulation of osteoclast acidityQ44647666
Parathyroid hormone-related protein and interleukin-1 alpha synergistically stimulate bone resorption in vitro and increase the serum calcium concentration in mice in vivoQ44903982
Production of lymphotoxin, a bone-resorbing cytokine, by cultured human myeloma cellsQ45211461
Inhibiting and stimulating effects of TGF-beta 1 on osteoclastic bone resorption in fetal mouse bone organ culturesQ46192845
Estrogen promotes apoptosis of murine osteoclasts mediated by TGF-beta.Q51005281
Osteoclastogenesis inhibitory factor (OCIF) directly inhibits bone-resorbing activity of isolated mature osteoclasts.Q52532345
Interleukin-4 inhibits spontaneous and parathyroid hormone-related protein-stimulated osteoclast formation in mice.Q53955397
Osteoclast differentiation factor (ODF) induces osteoclast-like cell formation in human peripheral blood mononuclear cell cultures.Q54137269
Preparation and characterization of a mouse osteoclast-like multinucleated cell population.Q54259715
1,25(OH)2D3 induces differentiation of osteoclast-like cells from human bone marrow cultures.Q54296184
Formation of osteoclasts and osteoblast-like cells in long-term human bone marrow cultures.Q54300589
Osteoblastic cells are involved in osteoclast formation.Q54374668
c-Fos: a key regulator of osteoclast-macrophage lineage determination and bone remodelingQ58326943
The murine mutation osteopetrosis is in the coding region of the macrophage colony stimulating factor geneQ59092154
Isolated osteoclasts in primary culture: first observations on structure and survival in culture media.Q64937800
Expression of human transforming growth factor alpha by Chinese hamster ovarian tumors in nude mice causes hypercalcemia and increased osteoclastic bone resorptionQ68231184
Osteoclast-like cell formation and its regulation by osteotropic hormones in mouse bone marrow culturesQ68274092
Identification of committed mononuclear precursors for osteoclast-like cells formed in long term human marrow culturesQ68504882
Interleukin-4 as a potent inhibitor of bone resorptionQ68610452
Prostaglandin E2 inhibits formation of osteoclastlike cells in long-term human marrow cultures but is not a mediator of the inhibitory effects of transforming growth factor betaQ68911249
A synthetic analogue of vitamin D3, 22-oxa-1 alpha,25-dihydroxyvitamin D3, is a potent modulator of in vivo immunoregulating activity without inducing hypercalcemia in miceQ69340235
Two squamous cell carcinomas not associated with humoral hypercalcemia produce a potent bone resorption-stimulating factor which is interleukin-1 alphaQ69353084
Parathyroid hormone (PTH) and PTH-like protein (PLP) stimulate interleukin-6 production by osteogenic cells: a possible role of interleukin-6 in osteoclastogenesisQ69354510
The bone marrow-derived stromal cell lines MC3T3-G2/PA6 and ST2 support osteoclast-like cell differentiation in cocultures with mouse spleen cellsQ69541163
Interleukin-1 and tumor necrosis factor stimulate the formation of human osteoclastlike cells in vitroQ69738552
Isolated osteoclasts and their presumed progenitor cells, the monocyte, in cultureQ70545151
Bisphosphonates promote apoptosis in murine osteoclasts in vitro and in vivoQ71207806
Ultrastructural immunocytochemical localization of carbonic anhydrase in normal and calcitonin-treated chick osteoclastsQ71632492
Comparative study of inhibitory effects by murine interferon ? and a new bisphosphonate (alendronate) in hypercalcemic, nude mice bearing human tumor (LJC-1-JCK)Q71649346
Stimulation of bone resorption in vitro by a non-prostanoid factor released by human monocytes in cultureQ71731720
Isolation and Characterization of Highly Enriched, Prefusion Mouse Osteoclastic CellsQ71975600
Osteoclast synthesis and secretion and activation of latent transforming growth factor betaQ72058811
Use of an in vivo model to determine the effects of interleukin-1 on cells at different stages in the osteoclast lineageQ72248104
Interleukin-4 modulates osteoclast differentiation and inhibits the formation of resorption pits in mouse osteoclast culturesQ72607646
Macrophage colony-stimulating factor release and receptor expression in bone cellsQ72763632
Ovariectomy decreases the mRNA levels of transforming growth factor-beta 1 and increases the mRNA levels of osteocalcin in rat bone in vivoQ72883377
Osteoprotegerin and its cognate ligand: a new paradigm of osteoclastogenesisQ77180502
P433issue8
P921main subjectcell biologyQ7141
P304page(s)1229-1241
P577publication date1999-08-01
P1433published inExperimental HematologyQ5421109
P1476titleCell biology of the osteoclast
P478volume27