PU.1 serves a critical role in the innate defense against Aspergillus fumigatus via dendritic cell-associated C-type lectin receptor-1 and toll-like receptors-2 and 4 in THP-1-derived macrophages

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PU.1 serves a critical role in the innate defense against Aspergillus fumigatus via dendritic cell-associated C-type lectin receptor-1 and toll-like receptors-2 and 4 in THP-1-derived macrophages is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3892/MMR.2017.6504
P932PMC publication ID5436209
P698PubMed publication ID28440496

P2093author name stringXin Su
Yi Shi
Min Wang
Wenkui Sun
Feng Cai
Chenyang Liu
Shen Geng
P2860cites workPathogenesis of Aspergillus fumigatus in Invasive AspergillosisQ24650911
Aspergillus fumigatus: principles of pathogenesis and host defenseQ24681995
Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT MethodQ25938999
Interference of Aspergillus fumigatus with the immune responseQ26865553
Allele-specific induction of IL-1β expression by C/EBPβ and PU.1 contributes to increased tuberculosis susceptibilityQ28396007
Why does the autoantibody against granulocyte-macrophage colony-stimulating factor cause lesions only in the lung?Q33232070
Downregulation of PU.1 leads to decreased expression of Dectin-1 in alveolar macrophages during Pneumocystis pneumoniaQ33676073
Gm-CSF regulates pulmonary surfactant homeostasis and alveolar macrophage-mediated innate host defenseQ34516299
Killing of Aspergillus fumigatus by alveolar macrophages is mediated by reactive oxidant intermediatesQ35011464
Aspergillus fumigatus and related speciesQ35045054
Functional PU.1 in macrophages has a pivotal role in NF-κB activation and neutrophilic lung inflammation during endotoxemiaQ35553597
Differential role of MyD88 in macrophage-mediated responses to opportunistic fungal pathogensQ35801720
Macrophage dectin-1 expression is controlled by leukotriene B4 via a GM-CSF/PU.1 axisQ36083704
Suppression of PU.1-linked TLR4 expression by cilostazol with decrease of cytokine production in macrophages from patients with rheumatoid arthritisQ36681771
Toll-like receptor 4 polymorphisms and aspergillosis in stem-cell transplantationQ37130676
Immune responses against Aspergillus fumigatus: what have we learned?Q37888393
The transcription factor PU.1 is a critical regulator of cellular communication in the immune systemQ37942506
Antifungal innate immunity: recognition and inflammatory networksQ38295131
miR-15a/16 regulates macrophage phagocytosis after bacterial infectionQ38433642
The innate immune response to Aspergillus fumigatus at the alveolar surface.Q38454116
Activation of NF-κB and respiratory burst following Aspergillus fumigatus stimulation of macrophagesQ39120431
Dectin-1 is inducible and plays a crucial role in Aspergillus-induced innate immune responses in human bronchial epithelial cellsQ39352928
Phagocytosis and intracellular fate of Aspergillus fumigatus conidia in alveolar macrophages.Q39714351
Aspergillus fumigatus antigens activate innate immune cells via toll-like receptors 2 and 4.Q40517084
Toll-like receptor (TLR) signaling in response to Aspergillus fumigatusQ40711523
An Adenoviral Vector Encoding Full-Length Dectin-1 Promotes Aspergillus-Induced Innate Immune Response in MacrophagesQ41257404
Epstein-Barr virus LMP2A suppresses MHC class II expression by regulating the B-cell transcription factors E47 and PU.1.Q41511529
Requisite role for the dectin-1 beta-glucan receptor in pulmonary defense against Aspergillus fumigatusQ42323203
Identification and characterization of enhancers controlling the inflammatory gene expression program in macrophages.Q43141233
TLR-2, TLR-4 and dectin-1 expression in human monocytes and neutrophils stimulated by Paracoccidioides brasiliensisQ43248755
GM-CSF regulates alveolar macrophage differentiation and innate immunity in the lung through PU.1.Q43774205
Binding of live conidia of Aspergillus fumigatus activates in vitro-generated human Langerhans cells via a lectin of galactomannan specificityQ44557364
Ehrlichia chaffeensis downregulates surface Toll-like receptors 2/4, CD14 and transcription factors PU.1 and inhibits lipopolysaccharide activation of NF-kappa B, ERK 1/2 and p38 MAPK in host monocytes.Q47284362
Transcriptional regulation of the human toll-like receptor 2 gene in monocytes and macrophagesQ48303295
The contribution of the Toll-like/IL-1 receptor superfamily to innate and adaptive immunity to fungal pathogens in vivo.Q51024797
Role of TNF-alpha in pulmonary host defense in murine invasive aspergillosis.Q54105543
Dectin-1 Y238X polymorphism associates with susceptibility to invasive aspergillosis in hematopoietic transplantation through impairment of both recipient- and donor-dependent mechanisms of antifungal immunityQ58855374
Toll-like receptor (TLR) 2 and TLR4 are essential for Aspergillus-induced activation of murine macrophagesQ73676366
Critical role of transcription factor PU.1 in the expression of CD80 and CD86 on dendritic cellsQ82674317
P433issue6
P921main subjectAspergillus fumigatusQ134359
toll-like receptorQ408004
dendritic cellQ506253
P304page(s)4084-4092
P577publication date2017-04-24
P1433published inMolecular Medicine ReportsQ26842180
P1476titlePU.1 serves a critical role in the innate defense against Aspergillus fumigatus via dendritic cell-associated C-type lectin receptor-1 and toll-like receptors-2 and 4 in THP-1-derived macrophages
P478volume15

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Q47099022Human and Murine Innate Immune Cell Populations Display Common and Distinct Response Patterns during Their In Vitro Interaction with the Pathogenic Mold Aspergillus fumigatuscites workP2860

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