Musashi-1 promotes a cancer stem cell lineage and chemoresistance in colorectal cancer cells

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Musashi-1 promotes a cancer stem cell lineage and chemoresistance in colorectal cancer cells is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1085436603
P356DOI10.1038/S41598-017-02057-9
P932PMC publication ID5438397
P698PubMed publication ID28526879

P50authorYuh-Jyh JongQ59681568
P2093author name stringChi-Chou Huang
Chun-Che Lin
Guang-Yuh Chiou
Ming-Chang Tsai
Hsuan-Yi Chen
Tzu-Wei Yang
Chia-Ying Tang
Jung-Yi Yen
Nurul Fadhilah
P2860cites workInhibition of mTORC1 by astrin and stress granules prevents apoptosis in cancer cellsQ24318126
Aldehyde dehydrogenase 1 is a marker for normal and malignant human colonic stem cells (SC) and tracks SC overpopulation during colon tumorigenesisQ24645253
Stress granules and processing bodies are dynamically linked sites of mRNP remodelingQ24678779
Discovery of colorectal cancer PIK3CA mutation as potential predictive biomarker: power and promise of molecular pathological epidemiologyQ27011884
Identification of stem cells in small intestine and colon by marker gene Lgr5Q28131701
Stress granules: the Tao of RNA triageQ29615263
The Wnt/beta-catenin pathway regulates growth and maintenance of colonospheresQ34075159
Increased Src activity disrupts cadherin/catenin-mediated homotypic adhesion in human colon cancer and transformed rodent cells.Q34125882
Formation of stress granules inhibits apoptosis by suppressing stress-responsive MAPK pathwaysQ34845865
p53 binding to nucleosomes within the p21 promoter in vivo leads to nucleosome loss and transcriptional activationQ35081442
Stress-Triggered Phase Separation Is an Adaptive, Evolutionarily Tuned Response.Q50963829
Induction of the stem-like cell regulator CD44 by Rho kinase inhibition contributes to the maintenance of colon cancer-initiating cells.Q53143685
Expression of variant CD44-messenger RNA in colorectal adenocarcinomas and adenomatous polyps in humans.Q53457031
Microsatellite instability in aberrant crypt foci from human colonsQ71900049
Inhibition of cyclo-oxygenase 2 expression in colon cells by the chemopreventive agent curcumin involves inhibition of NF-kappaB activation via the NIK/IKK signalling complexQ73171123
Cyclooxygenase 2 expression is increased in the stroma of colon carcinomas from IL-10(-/-) miceQ73386832
Knockdown of RNA binding protein musashi-1 leads to tumor regression in vivoQ81253069
The impact of Aldehyde dehydrogenase 1 expression on prognosis for metastatic colon cancerQ88130239
HIF induces human embryonic stem cell markers in cancer cells.Q35085958
Musashi-1 maintains blood-testis barrier structure during spermatogenesis and regulates stress granule formation upon heat stressQ35621986
Targeting of KRAS mutant tumors by HSP90 inhibitors involves degradation of STK33.Q35894216
Differential effects of oncogenic K-Ras and N-Ras on proliferation, differentiation and tumor progression in the colonQ36697241
The Msi Family of RNA-Binding Proteins Function Redundantly as Intestinal OncoproteinsQ36972882
IL-4-mediated drug resistance in colon cancer stem cellsQ37072312
Colorectal cancer expression of peroxisome proliferator-activated receptor gamma (PPARG, PPARgamma) is associated with good prognosisQ37146010
A two-step model for colon adenoma initiation and progression caused by APC lossQ37251442
Epigenetic and genetic features of 24 colon cancer cell linesQ37275764
Musashi-1 regulates AKT-derived IL-6 autocrinal/paracrinal malignancy and chemoresistance in glioblastomaQ37520595
Incidence trends and predictors for cost and average lengths of stay in colorectal cancer surgeryQ37581369
Colon cancer stem cells: promise of targeted therapy.Q37737414
Tests and investigations for colorectal cancer screeningQ38207418
SNAIL regulates interleukin-8 expression, stem cell-like activity, and tumorigenicity of human colorectal carcinoma cellsQ38334630
Musashi signaling in stem cells and cancerQ38632808
TIA1 oxidation inhibits stress granule assembly and sensitizes cells to stress-induced apoptosisQ38806111
Principles and Properties of Stress GranulesQ38862341
5-Fluorouracil affects assembly of stress granules based on RNA incorporationQ39004547
NOTCH3 signaling regulates MUSASHI-1 expression in metastatic colorectal cancer cellsQ39024084
Maintenance of the stemness in CD44(+) HCT-15 and HCT-116 human colon cancer cells requires miR-203 suppressionQ39075158
Musashi RNA-Binding Proteins as Cancer Drivers and Novel Therapeutic TargetsQ39112430
TGF-beta receptor inactivation and mutant Kras induce intestinal neoplasms in mice via a beta-catenin-independent pathwayQ39885215
CD44-positive colorectal adenoma cells express the potential stem cell markers musashi antigen (msi1) and ephrin B2 receptor (EphB2).Q40091567
Molecular pathways: PI3K pathway phosphatases as biomarkers for cancer prognosis and therapyQ40740686
Mutant p53 DNA clones from human colon carcinomas cooperate with ras in transforming primary rat cells: a comparison of the "hot spot" mutant phenotypesQ41946290
Clues to the pathogenesis of familial colorectal cancerQ42622043
Musashi1 cooperates in abnormal cell lineage protein 28 (Lin28)-mediated let-7 family microRNA biogenesis in early neural differentiationQ42730615
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesImageJQ1659584
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectcolorectal cancerQ188874
neoplastic stem cellsQ1638475
colorectal carcinomaQ25493920
P304page(s)2172
P577publication date2017-05-19
P1433published inScientific ReportsQ2261792
P1476titleMusashi-1 promotes a cancer stem cell lineage and chemoresistance in colorectal cancer cells
P478volume7

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cites work (P2860)
Q61795967AU-rich element-binding proteins in colorectal cancer
Q52571378Cancer Stem Cells (CSCs) in Drug Resistance and their Therapeutic Implications in Cancer Treatment.
Q58784185Identification of a novel splice variant of the human musashi-1 gene
Q90737551Musashi-1: An Example of How Polyalanine Tracts Contribute to Self-Association in the Intrinsically Disordered Regions of RNA-Binding Proteins
Q48016360Structural Insight into the Recognition of r(UAG) by Musashi-1 RBD2, and Construction of a Model of Musashi-1 RBD1-2 Bound to the Minimum Target RNA.
Q90472168Tex10 is upregulated and promotes cancer stem cell properties and chemoresistance in hepatocellular carcinoma
Q99241248Understanding the roles of stress granule during chemotherapy for patients with malignant tumors
Q92331491Upregulation of musashi1 increases malignancy of hepatocellular carcinoma via the Wnt/β-catenin signaling pathway and predicts a poor prognosis
Q92153514microRNA: The Impact on Cancer Stemness and Therapeutic Resistance