| review article | Q7318358 |
| scholarly article | Q13442814 |
| P356 | DOI | 10.1016/S0014-2999(99)00330-1 |
| P698 | PubMed publication ID | 10443562 |
| P2093 | author name string | Skolnick P | |
| P2860 | cites work | Differential display of eukaryotic messenger RNA by means of the polymerase chain reaction | Q28131789 |
| Is the forced swimming test a suitable model for revealing antidepressant activity? | Q28290947 | ||
| Effect of pindolol in hastening response to fluoxetine in the treatment of major depression: a double-blind, placebo-controlled trial | Q71957986 | ||
| 1-Aminocyclopropanecarboxylic acid protects against dynorphin A-induced spinal injury | Q72389867 | ||
| Efficacy of papaverine addition for treatment-refractory major depression | Q73196332 | ||
| The AMPA receptor interacts with and signals through the protein tyrosine kinase Lyn | Q28294274 | ||
| Regulation of transcription by MAP kinase cascades | Q29618477 | ||
| Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses | Q29618915 | ||
| Recent advances in the phencyclidine model of schizophrenia | Q29618917 | ||
| Neurotrophins and depression | Q33547892 | ||
| Modulation of N-methyl-D-aspartate receptor function by glycine transport | Q33609600 | ||
| A molecular and cellular theory of depression | Q34064955 | ||
| Validity, reliability and utility of the chronic mild stress model of depression: a 10-year review and evaluation | Q34065888 | ||
| Functional antagonists at the NMDA receptor complex exhibit antidepressant actions | Q34196683 | ||
| Antidepressant activity of non-competitive and competitive NMDA receptor antagonists in a chronic mild stress model of depression | Q34315937 | ||
| The excitatory amino acid antagonist D-CPP-ene (SDZ EAA-494) in patients with epilepsy | Q34347037 | ||
| Potential antidepressive properties of amantadine, memantine and bifemelane | Q34353745 | ||
| Psychotogenicity and N-methyl-D-aspartate receptor antagonism: implications for neuroprotective pharmacotherapy. | Q34415261 | ||
| The antidepressant metapramine is a low-affinity antagonist at N-methyl-D-aspartic acid receptors | Q34419982 | ||
| Glutamate neurotoxicity and diseases of the nervous system | Q34560997 | ||
| Transsynaptic control of gene expression | Q40852594 | ||
| Chronic antidepressant administration increases the expression of cAMP response element binding protein (CREB) in rat hippocampus. | Q42556936 | ||
| A rapid method for evaluating the behavioral effects of phencyclidine-like dissociative anesthetics in mice | Q44334290 | ||
| Chronic treatment with 1-aminocyclopropanecarboxylic acid desensitizes behavioral responses to compounds acting at the N-methyl-D-aspartate receptor complex | Q45235868 | ||
| Amino-alkyl-cyclohexanes are novel uncompetitive NMDA receptor antagonists with strong voltage-dependency and fast blocking kinetics: in vitro and in vivo characterization | Q48244565 | ||
| Brain-derived neurotrophic factor (BDNF) protects cultured rat cerebellar granule neurons against glucose deprivation-induced apoptosis | Q48320220 | ||
| Chronic administration of imipramine and citalopram alters the expression of NMDA receptor subunit mRNAs in mouse brain. A quantitative in situ hybridization study | Q48377216 | ||
| Brain-derived neurotrophic factor and basic fibroblast growth factor downregulate NMDA receptor function in cerebellar granule cells. | Q48393485 | ||
| Chronic antidepressant treatments increase cytochrome b mRNA levels in mouse cerebral cortex | Q48524844 | ||
| 1-aminocyclopropanecarboxylates exhibit antidepressant and anxiolytic actions in animal models | Q48638368 | ||
| The receptor antagonist MK-801 induces increases in dopamine and serotonin metabolism in several brain regions of rats | Q48687180 | ||
| Single doses of MK-801, a non-competitive antagonist of NMDA receptors, increase the number of 5-HT1A serotonin receptors in the rat brain | Q48707737 | ||
| A novel mechanism of activity-dependent NMDA receptor antagonism describes the effect of ifenprodil in rat cultured cortical neurones | Q48829389 | ||
| Regulation of alternative splicing of NMDAR1 in the kindling model | Q48919909 | ||
| 1-Aminocyclopropane-carboxylic acid reduces NMDA-induced hippocampal neurodegeneration in vivo. | Q49160127 | ||
| Brain-derived neurotrophic factor promotes the survival and sprouting of serotonergic axons in rat brain. | Q50755884 | ||
| Lack of amnestic, psychotomimetic or impairing effect on psychomotor performance of eliprodil, a new NMDA antagonist. | Q51131840 | ||
| Regulation of BDNF and trkB mRNA in rat brain by chronic electroconvulsive seizure and antidepressant drug treatments. | Q52012874 | ||
| Repeated ECS induces GluR1 mRNA but not NMDAR1A-G mRNA in the rat hippocampus. | Q52050254 | ||
| The prevalence of depressive disorders in the United Kingdom. | Q52223970 | ||
| Antidepressant-like effects of a partial agonist at strychnine-insensitive glycine receptors and a competitive NMDA receptor antagonist. | Q53976705 | ||
| Norepinephrine-independent regulation of GRII mRNA in vivo by a tricyclic antidepressant. | Q55063897 | ||
| PDE 4 inhibitors: the use of molecular cloning in the design and development of novel drugs | Q57994824 | ||
| Adaptation of cortical but not hippocampal NMDA receptors after chronic citalopram treatment | Q60473708 | ||
| Pindolol Induces a Rapid Improvement of Depressed Patients Treated With Serotonin Reuptake Inhibitors | Q60641052 | ||
| Effects of MK-801 and antidepressant drugs in the forced swimming test in rats | Q68222773 | ||
| Ethanol inhibits NMDA-induced increases in free intracellular Ca2+ in dissociated brain cells | Q69375128 | ||
| Antidepressant-like actions of the polyamine site NMDA antagonist, eliprodil (SL-82.0715) | Q70853351 | ||
| 1-Aminocyclopropanecarboxylic acid: mouse to man interspecies pharmacokinetic comparisons and allometric relationships | Q71520718 | ||
| Ligand affinities at recombinant N-methyl-D-aspartate receptors depend on subunit composition | Q71665346 | ||
| Antidepressant-like effects of 1-aminocyclopropanecarboxylic acid and D-cycloserine in an animal model of depression | Q71943023 | ||
| P433 | issue | 1-3 | |
| P407 | language of work or name | English | Q1860 |
| P1104 | number of pages | 10 | |
| P304 | page(s) | 31-40 | |
| P577 | publication date | 1999-06-01 | |
| P1433 | published in | European Journal of Pharmacology | Q1376712 |
| P1476 | title | Antidepressants for the new millennium | |
| P478 | volume | 375 |
| Q44345436 | 2-(3,4-Dihydro-1H-isoquinolin-2yl)-pyridines as a novel class of NR1/2B subtype selective NMDA receptor antagonists |
| Q40619459 | A common role for psychotropic medications: memory impairment |
| Q38771892 | A complex interaction between glycine/NMDA receptors and serotonergic/noradrenergic antidepressants in the forced swim test in mice |
| Q36148434 | A pathophysiological paradigm for the therapy of psychiatric disease |
| Q30987882 | A pilot in vivo proton magnetic resonance spectroscopy study of amino acid neurotransmitter response to ketamine treatment of major depressive disorder. |
| Q35753372 | AMPA Receptor-mTOR Activation is Required for the Antidepressant-Like Effects of Sarcosine during the Forced Swim Test in Rats: Insertion of AMPA Receptor may Play a Role |
| Q41146080 | AVP and Glu systems interact to regulate levels of anxiety in BALB/cJ mice |
| Q44270223 | Activation of the TrkB neurotrophin receptor is induced by antidepressant drugs and is required for antidepressant-induced behavioral effects. |
| Q47691548 | Acute change in anterior cingulate cortex GABA, but not glutamine/glutamate, mediates antidepressant response to citalopram |
| Q44239962 | Adaptation of monoaminergic responses to phencyclidine in nucleus accumbens and prefrontal cortex following repeated treatment with fluoxetine or imipramine. |
| Q44407262 | Adaptive changes in the reactivity of 5-HT1A and 5-HT2 receptors induced in rat frontal cortex by repeated imipramine and citalopram |
| Q30457479 | Advances in the treatment of anxiety: targeting glutamate |
| Q78440735 | Antidepressant activity and calcium signaling cascades |
| Q34622363 | Antidepressant mechanisms: functional and molecular correlates of excitatory amino acid neurotransmission |
| Q37642659 | Antidepressant properties of aqueous macerate from Gladiolus dalenii corms |
| Q53972514 | Antidepressant-like actions of an AMPA receptor potentiator (LY392098). |
| Q44462663 | Antidepressant-like effect of agmatine and its possible mechanism |
| Q50524549 | Antidepressant-like effects of L-theanine in the forced swim and tail suspension tests in mice. |
| Q42602477 | Antidepressant-like effects of acute and chronic treatment with zinc in forced swim test and olfactory bulbectomy model in rats |
| Q43685912 | Antidepressant-like properties of zinc in rodent forced swim test |
| Q33751924 | Antidepressants are a rational complementary therapy for the treatment of Alzheimer's disease |
| Q34061082 | Antidepressants: past, present and future |
| Q36654331 | Are compounds acting at metabotropic glutamate receptors the answer to treating depression? |
| Q33231128 | Beyond monoamines: glutamatergic function in mood disorders |
| Q35106821 | Biochemical and molecular studies using human autopsy brain tissue |
| Q35237067 | Cellular and molecular mechanisms in the long-term action of antidepressants |
| Q34123893 | Cellular mechanisms in the vulnerability to depression and response to antidepressants |
| Q46829332 | Changes in AMPA subunit expression in the mouse brain after chronic treatment with the antidepressant maprotiline: a link between noradrenergic and glutamatergic function? |
| Q43800935 | Chronic administration of amitriptyline and caffeine in a rat model of neuropathic pain: multiple interactions |
| Q46979618 | Chronic antidepressants potentiate via sigma-1 receptors the brain-derived neurotrophic factor-induced signaling for glutamate release |
| Q46412677 | Chronic antidepressants reduce depolarization-evoked glutamate release and protein interactions favoring formation of SNARE complex in hippocampus. |
| Q51075863 | Chronic treatment with antidepressants affects glycine/NMDA receptor function: behavioral evidence. |
| Q44813046 | Comprehensive expression analysis of a rat depression model |
| Q28244223 | Current investigational drugs for major depression |
| Q38526070 | Depression-Related Behavioral Tests |
| Q48955474 | Effect of chronic administration of ketamine on the mitochondrial respiratory chain activity caused by chronic mild stress |
| Q48540752 | Effect of chronic imipramine or electroconvulsive shock on the expression of mGluR1a and mGluR5a immunoreactivity in rat brain hippocampus. |
| Q43244719 | Effect of repeated co-treatment with fluoxetine and amantadine on the behavioral reactivity of the central dopamine and serotonin system in rats |
| Q48189003 | Effectiveness of zinc in modulating lithium induced biochemical and behavioral changes in rat brain |
| Q41861044 | Effects of amantadine and budipine on antidepressant drug-evoked changes in extracellular 5-HT in the frontal cortex of freely moving rats |
| Q44920267 | Effects of antidepressant drug imipramine on gene expression in rat prefrontal cortex. |
| Q34065490 | Elevated levels of the NR2C subunit of the NMDA receptor in the locus coeruleus in depression |
| Q36730674 | Emerging treatments for major depression |
| Q44490783 | Enhancement of antidepressant potency by a potentiator of AMPA receptors |
| Q35111592 | Enhancing neuronal plasticity and cellular resilience to develop novel, improved therapeutics for Difficult-to-Treat depression |
| Q35236446 | Enhancing synaptic plasticity and cellular resilience to develop novel, improved treatments for mood disorders. |
| Q92534355 | Exposure and Response Prevention in the Treatment of Obsessive-Compulsive Disorder: Current Perspectives |
| Q61643450 | Expression of Neurotrophins BDNF and NT-3, and Their Receptors in Rat Brain After Administration of Antipsychotic and Psychotrophic Agents |
| Q28769065 | Facts, interpretations, and explanations: a review of Evelyn Fox Keller's Making sense of life |
| Q48308828 | Glia mechanisms in mood regulation: a novel model of mood disorders |
| Q44456005 | Glutamate release in the nucleus accumbens is involved in behavioral depression during the PORSOLT swim test |
| Q38895017 | Glutamate-Based Drug Discovery for Novel Antidepressants |
| Q47831328 | Glutamatergic system and mTOR-signaling pathway participate in the antidepressant-like effect of inosine in the tail suspension test. |
| Q38344660 | Identification of genes regulated by memantine and MK-801 in adult rat brain by cDNA microarray analysis |
| Q73088643 | Imipramine and phenelzine decrease glutamate overflow in the prefrontal cortex--a possible mechanism of neuroprotection in major depression? |
| Q48509791 | Increased stress-evoked nitric oxide signalling in the Flinders sensitive line (FSL) rat: a genetic animal model of depression |
| Q33231185 | Inhibition of N-methyl-D-aspartate receptor function appears to be one of the common actions for antidepressants |
| Q43884683 | Inhibition of glutamate release by fluspirilene in cerebrocortical nerve terminals (synaptosomes). |
| Q28241221 | Invited review: the evolution of antidepressant mechanisms |
| Q44567452 | Involvement of NMDA receptors and L-arginine-nitric oxide pathway in the antidepressant-like effects of zinc in mice. |
| Q37147169 | Is major depressive disorder a metabolic encephalopathy? |
| Q38189551 | Is the mGlu5 receptor a possible target for new antidepressant drugs? |
| Q34978041 | Ketamine and the next generation of antidepressants with a rapid onset of action |
| Q43061598 | Ketamine induces rapid onset of antidepressant action: neurophysiological biomarkers as predictors of effect |
| Q38254452 | Ketamine: promising path or false prophecy in the development of novel therapeutics for mood disorders? |
| Q53441048 | Lack of metabolism in (R)-ketamine's antidepressant actions in a chronic social defeat stress model. |
| Q34615607 | Lamotrigine update and its use in mood disorders |
| Q42528653 | Local, but not systemic, administration of serotonergic antidepressants decreases hippocampal nitric oxide synthase activity |
| Q34071706 | Low nNOS protein in the locus coeruleus in major depression |
| Q44443003 | Melatonin exerts an antidepressant-like effect in the tail suspension test in mice: evidence for involvement of N-methyl-D-aspartate receptors and the L-arginine-nitric oxide pathway. |
| Q47777693 | Methoxetamine affects brain processing involved in emotional response in rats. |
| Q46327960 | Methylene blue and its analogues as antidepressant compounds. |
| Q80188585 | Modulation of antidepressant-like activity of magnesium by serotonergic system |
| Q34110275 | Modulation of defensive behavior by periaqueductal gray NMDA/glycine-B receptor |
| Q34785753 | Modulation of synaptic plasticity by stress and antidepressants |
| Q35001313 | Molecular targets in the treatment of anxiety |
| Q34147832 | Multiple MPEP administrations evoke anxiolytic- and antidepressant-like effects in rats |
| Q38211107 | NMDA antagonists under investigation for the treatment of major depressive disorder |
| Q44000229 | NMDA receptor involvement in imipramine withdrawal-associated effects on swim stress, GABA levels and NMDA receptor binding in rat hippocampus |
| Q92993515 | NMDA receptors and L-arginine/nitric oxide/cyclic guanosine monophosphate pathway contribute to the antidepressant-like effect of Yueju pill in mice |
| Q37323300 | NMDA receptors and the L-arginine-nitric oxide-cyclic guanosine monophosphate pathway are implicated in the antidepressant-like action of the ethanolic extract from Tabebuia avellanedae in mice |
| Q35587678 | Neurobiology of antidepressant withdrawal: implications for the longitudinal outcome of depression |
| Q28238686 | Neurobiology of mood, anxiety, and emotions as revealed by studies of a unique antidepressant: tianeptine |
| Q24656267 | Neurochemistry of the nucleus accumbens and its relevance to depression and antidepressant action in rodents |
| Q42754399 | Neuroprotective potential of mGluR5 antagonist MTEP: effects on kainate-induced excitotoxicity in the rat hippocampus |
| Q44519524 | Neurotransmitters, neurosteroids and neurotrophins: new models of the pathophysiology and treatment of depression |
| Q35794547 | Neurotrophins as mediators of drug effects on mood, addiction, and neuroprotection |
| Q34507177 | New targets for rapid antidepressant action |
| Q35045542 | Nicotine and nicotinic receptor antagonists potentiate the antidepressant-like effects of imipramine and citalopram. |
| Q30494165 | Nitric oxide as inflammatory mediator in post-traumatic stress disorder (PTSD): evidence from an animal model. |
| Q95643364 | Novel Targets for Fast Antidepressant Responses: Possible Role of Endogenous Neuromodulators |
| Q77291802 | Novel treatments for anxiety and depression: hurdles in bringing them to the market |
| Q38155089 | Nutritional strategies for dealing with depression |
| Q34517414 | Pharmacological profile of the "triple" monoamine neurotransmitter uptake inhibitor, DOV 102,677. |
| Q34458418 | Potential and current use of N-methyl-D-aspartate (NMDA) receptor antagonists in diseases of aging |
| Q24673932 | Potential anxiolytic- and antidepressant-like effects of MPEP, a potent, selective and systemically active mGlu5 receptor antagonist |
| Q58795712 | Pre-reproductive stress and fluoxetine treatment in rats affect offspring A-to-I RNA editing, gene expression and social behavior |
| Q36472992 | Prospects for the treatment of depression |
| Q46165761 | Proteomic-based genotyping in a mouse model of trait anxiety exposes disease-relevant pathways |
| Q44666870 | Reduced isolation-induced aggressiveness in mice following NAALADase inhibition. |
| Q44535421 | Repeated administration of antidepressants decreases field potentials in rat frontal cortex |
| Q37271539 | Role of zinc in maternal and child mental health |
| Q44340961 | Selective regulation of presynaptic calcium/calmodulin-dependent protein kinase II by psychotropic drugs |
| Q60473700 | Serum trace elements in animal models and human depression: Part III. Magnesium. Relationship with copper |
| Q36101382 | Strategies for producing faster acting antidepressants. |
| Q44284822 | Stress- and antidepressant treatment-induced modifications of 5-HT₇ receptor functions in the rat brain |
| Q44590996 | Subunit selective decrease of AMPA and metabotropic glutamate receptor mRNA expression in rat brain by systemic administration of the NMDA receptor blocker MK-801. |
| Q44071645 | Synergistic effect of uncompetitive NMDA receptor antagonists and antidepressant drugs in the forced swimming test in rats |
| Q37481603 | Targeting glutamatergic signaling for the development of novel therapeutics for mood disorders |
| Q33989695 | The N-methyl-D-aspartate receptor, synaptic plasticity, and depressive disorder. A critical review |
| Q34528009 | The antidepressant tianeptine persistently modulates glutamate receptor currents of the hippocampal CA3 commissural associational synapse in chronically stressed rats. |
| Q48143108 | The effects of fluoxetine treatment in a chronic mild stress rat model on depression-related behavior, brain neurotrophins and ERK expression |
| Q43676192 | The effects of reboxetine treatment on depression-like behavior, brain neurotrophins, and ERK expression in rats exposed to chronic mild stress |
| Q39202075 | The failure of the antidepressant drug discovery process is systemic. |
| Q41630586 | The modulation of NMDA receptors and L-arginine/nitric oxide pathway is implicated in the anti-immobility effect of creatine in the tail suspension test. |
| Q34075093 | Therapeutic potential of NMDA receptor antagonists in the treatment of alcohol and substance use disorders |
| Q24632936 | Towards a glutamate hypothesis of depression: an emerging frontier of neuropsychopharmacology for mood disorders |
| Q35743638 | Trends in the development of new antidepressants. Is there a light at the end of the tunnel? |
| Q48436906 | Zinc deficiency alters responsiveness to antidepressant drugs in mice |
| Q26786214 | Zinc in the Glutamatergic Theory of Depression |
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