Abnormal P-selectin localization during megakaryocyte development determines thrombosis in the gata1low model of myelofibrosis

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Abnormal P-selectin localization during megakaryocyte development determines thrombosis in the gata1low model of myelofibrosis is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3109/09537104.2013.840720
P932PMC publication ID4045657
P698PubMed publication ID24176039

P50authorMaria ZingarielloQ57067419
P2093author name stringAnna Rita Migliaccio
Eva Zetterberg
Fabrizio Martelli
Emanuela D'Amore
Laura Sancillo
Rosa Alba Rana
Maria Verrucci
P2860cites workProteomic and functional characterisation of platelet microparticle size classesQ50312260
Leukocyte- and platelet-derived microparticles correlate with thrombus weight and tissue factor activity in an experimental mouse model of venous thrombosis.Q51732019
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Impact of antithrombin deficiency in thrombogenesis: lipopolysaccharide and stress-induced thrombus formation in heterozygous antithrombin-deficient miceQ58211924
Thrombosis in primary myelofibrosis: incidence and risk factorsQ61050096
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Ultrastructural characterization of maturation, platelet release, and senescence of human cultured megakaryocytesQ61819548
Markers of platelet activation and platelet-leukocyte interaction in patients with myeloproliferative syndromesQ73012008
Leukocyte-leukocyte interactions mediated by platelet microparticles under flowQ73426888
Myelofibrosis with myeloid metaplasiaQ73712758
Angiogenesis in P- and E-selectin-deficient miceQ77466532
Leukocytosis is a risk factor for thrombosis in essential thrombocythemia: interaction with treatment, standard risk factors, and Jak2 mutation statusQ79365558
Frequency and risk factors for thrombosis in idiopathic myelofibrosis: analysis in a series of 155 patients from a single institutionQ81528363
Leukocyte-platelet interaction in patients with essential thrombocythemia and polycythemia veraQ28174281
Indices of platelet activation and the stability of coronary artery diseaseQ28221194
Accumulation of tissue factor into developing thrombi in vivo is dependent upon microparticle P-selectin glycoprotein ligand 1 and platelet P-selectinQ31144359
Consequences of GATA-1 deficiency in megakaryocytes and plateletsQ33328560
Accentuated response to phenylhydrazine and erythropoietin in mice genetically impaired for their GATA-1 expression (GATA-1(low) mice).Q33337239
Effects of the R216Q mutation of GATA-1 on erythropoiesis and megakaryocytopoiesisQ33358292
Human phenotypes associated with GATA-1 mutationsQ33381670
X-linked thrombocytopenia with thalassemia in two families in Sweden. Consider hereditary causes of thrombocytopenia and bone marrow fibrosisQ33403427
Platelet - leukocyte interactions: multiple links between inflammation, blood coagulation and vascular risk.Q34549341
Microparticles in hemostasis and thrombosis.Q35131040
Pro-coagulant state resulting from high levels of soluble P-selectin in bloodQ35578042
The hypomorphic Gata1low mutation alters the proliferation/differentiation potential of the common megakaryocytic-erythroid progenitorQ35628909
Multiple, targeted deficiencies in selectins reveal a predominant role for P-selectin in leukocyte recruitment.Q35651662
A "knockdown" mutation created by cis-element gene targeting reveals the dependence of erythroid cell maturation on the level of transcription factor GATA-1.Q36240033
An upstream, DNase I hypersensitive region of the hematopoietic-expressed transcription factor GATA-1 gene confers developmental specificity in transgenic miceQ36299027
GATA-1 as a regulator of mast cell differentiation revealed by the phenotype of the GATA-1low mouse mutantQ36370557
New insights into the pathogenesis of JAK2 V617F-positive myeloproliferative disorders and consequences for the management of patients.Q36524052
Thrombosis in myeloproliferative disorders: prevalence, prognostic factors, and the role of leukocytes and JAK2V617F.Q36831712
Differential localization of P-selectin and von Willebrand factor during megakaryocyte maturationQ36979002
Gata1 expression driven by the alternative HS2 enhancer in the spleen rescues the hematopoietic failure induced by the hypomorphic Gata1low mutationQ37348257
Altered SDF-1/CXCR4 axis in patients with primary myelofibrosis and in the Gata1 low mouse model of the diseaseQ37353939
P-selectin glycoprotein ligand-1 plays a crucial role in the selective recruitment of leukocytes into the atherosclerotic arterial wall.Q37612342
Platelet–Leukocyte Interactions in Cardiovascular Disease and BeyondQ37808902
Incidence and risk factors for bleeding in 1104 patients with essential thrombocythemia or prefibrotic myelofibrosis diagnosed according to the 2008 WHO criteria.Q37934479
Platelet-leukocyte interactions in thrombosisQ37954861
Front-line therapy in polycythemia vera and essential thrombocythemiaQ38025532
Thrombotic disease in the myeloproliferative neoplasms.Q38066925
Bleeding and thrombosis in the myeloproliferative disordersQ40179485
Soluble P-selectin and the risk of future cardiovascular eventsQ40729226
Development of myelofibrosis in mice genetically impaired for GATA-1 expression (GATA-1(low) mice).Q44083612
Effect of P-selectin on phosphatidylserine exposure and surface-dependent thrombin generation on monocytesQ45261378
Platelet-derived microparticles promote invasiveness of prostate cancer cells via upregulation of MMP-2 production.Q46186672
Characterization of the in vivo antiplatelet activity of the antihypertensive agent losartanQ46674485
Increased platelet, leukocyte, and coagulation activation in primary myelofibrosisQ46979105
Markers of endothelial and in vivo platelet activation in patients with essential thrombocythemia and polycythemia veraQ47416647
P433issue7
P921main subjectthrombosisQ261327
myelofibrosisQ1752571
P304page(s)539-547
P577publication date2013-10-31
P1433published inPlateletsQ1573582
P1476titleAbnormal P-selectin localization during megakaryocyte development determines thrombosis in the gata1low model of myelofibrosis
P478volume25

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cites work (P2860)
Q50201003GATA1 insufficiencies in primary myelofibrosis and other hematopoietic disorders: consequences for therapy
Q58701086Megakaryocyte Contribution to Bone Marrow Fibrosis: many Arrows in the Quiver
Q60922706New insights into the causes of thrombotic events in patients with myeloproliferative neoplasms raise the possibility of novel therapeutic approaches
Q33438367The transcription factor GATA1 regulates NBEAL2 expression through a long-distance enhancer
Q90592727Thrombotic, inflammatory, and HIF-regulated genes and thrombosis risk in polycythemia vera and essential thrombocythemia
Q60922703Vascular endothelial cell expression of JAK2 is sufficient to promote a pro-thrombotic state due to increased P-selectin expression

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