Therapeutic potential of anti-interleukin-17A aptamer: suppression of interleukin-17A signaling and attenuation of autoimmunity in two mouse models.

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Therapeutic potential of anti-interleukin-17A aptamer: suppression of interleukin-17A signaling and attenuation of autoimmunity in two mouse models. is …
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scholarly articleQ13442814

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P356DOI10.1002/ART.30108
P698PubMed publication ID20967861
P5875ResearchGate publication ID47521526

P50authorAkira IshiguroQ85227034
P2093author name stringJun-ichiro Inoue
Taishin Akiyama
Yoshikazu Nakamura
Hironori Adachi
P2860cites workRequirement of tumor necrosis factor receptor-associated factor (TRAF)6 in interleukin 17 signal transductionQ24676400
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IL-17 is increased in asthmatic airways and induces human bronchial fibroblasts to produce cytokinesQ34090258
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RNA aptamers to mammalian initiation factor 4G inhibit cap-dependent translation by blocking the formation of initiation factor complexesQ35057518
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Interleukin-17: a novel inflammatory cytokine that bridges innate and adaptive immunityQ36991727
Aptamers as candidate therapeutics for cardiovascular indicationsQ37068323
Increased osteopontin expression in dendritic cells amplifies IL-17 production by CD4+ T cells in experimental autoimmune encephalomyelitis and in multiple sclerosisQ37121507
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Blocking of interleukin-17 during reactivation of experimental arthritis prevents joint inflammation and bone erosion by decreasing RANKL and interleukin-1.Q38594831
Identification of an interleukin 17F/17A heterodimer in activated human CD4+ T cellsQ42170048
RNA aptamers to initiation factor 4A helicase hinder cap-dependent translation by blocking ATP hydrolysisQ43171380
Low prevalence of antibodies to glucose-6-phosphate isomerase in patients with rheumatoid arthritis and a spectrum of other chronic autoimmune disorders.Q44398367
Immunization with glucose-6-phosphate isomerase induces T cell-dependent peripheral polyarthritis in genetically unaltered miceQ44807490
Crucial role of the interleukin-6/interleukin-17 cytokine axis in the induction of arthritis by glucose-6-phosphate isomeraseQ46724756
P433issue2
P921main subjectinterleukinsQ194908
P304page(s)455-466
P577publication date2011-02-01
P1433published inArthritis and RheumatismQ23929027
P1476titleTherapeutic potential of anti-interleukin-17A aptamer: suppression of interleukin-17A signaling and attenuation of autoimmunity in two mouse models
P478volume63