A placebo-controlled trial of isoprinosine in patients with multiple sclerosis

scientific article

A placebo-controlled trial of isoprinosine in patients with multiple sclerosis is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1136/JNNP.57.2.164
P932PMC publication ID1072442
P698PubMed publication ID7510330
P5875ResearchGate publication ID15689435

P2093author name stringCompston DA
Miller DH
Milligan NM
P2860cites workAbility of isoprinosine to restore interleukin-2 production and T cell proliferation in autoimmune miceQ68942593
[Clinical and immunological improvement of remittent multiple sclerosis by isoprinosine. Randomized pilot study]Q68964394
Relative efficacy of intravenous methylprednisolone and ACTH in the treatment of acute relapse in MSQ69351477
Moderate efficacy of isoprinosine as a therapy for rheumatoid arthritisQ72383099
Inosiplex therapy in subacute sclerosing panencephalitis. A multicentre, non-randomised study in 98 patientsQ72665999
Long-term follow-up of patients with subacute sclerosing panencephalitis treated with inosiplexQ72672514
Immunomodulation by isoprinosine: effects on in vitro immune functions of lymphocytes from humans with autoimmune diseasesQ72700913
Rating neurologic impairment in multiple sclerosis: An expanded disability status scale (EDSS)Q22241644
Randomised double blind controlled trial of cyclosporin in multiple sclerosisQ30495856
Immunosuppressive effects of isoprinosine in man: a comparison to chlorambucil effects in multiple sclerosisQ33412934
Randomised, double blind, placebo controlled trial of inosine pranobex in rheumatoid arthritisQ33562594
A double-blind controlled trial of high dose methylprednisolone in patients with multiple sclerosis: 1. Clinical effectsQ33628316
Intensive immunosuppression in progressive multiple sclerosis. A randomized, three-arm study of high-dose intravenous cyclophosphamide, plasma exchange, and ACTH.Q34253953
New diagnostic criteria for multiple sclerosis: guidelines for research protocolsQ34271601
Partial restoration of impaired interleukin-2 production and Tac antigen (putative interleukin-2 receptor) expression in patients with acquired immune deficiency syndrome by isoprinosine treatment in vitroQ34627351
Interferon beta-1b is effective in relapsing-remitting multiple sclerosis. II. MRI analysis results of a multicenter, randomized, double-blind, placebo-controlled trial. UBC MS/MRI Study Group and the IFNB Multiple Sclerosis Study GroupQ34730962
Subacute sclerosing panencephalitis in black children--a review of 18 casesQ37969258
Inosine pranobex. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacyQ38169588
Inosiplex in the Treatment of Subacute Sclerosing PanencephalitisQ39552955
Progressive rubella panencephalitis: immunovirological studies and results of isoprinosine therapyQ39553444
Exacerbations of multiple sclerosis in patients treated with gamma interferonQ40797798
Limiting and repairing the damage in multiple sclerosisQ41602445
Overview of azathioprine treatment in multiple sclerosisQ42033600
Methisoprinol in the treatment of multiple sclerosis. A pilot studyQ43517712
Changes in visual evoked potentials in patients with multiple sclerosis treated with isoprinosine and amantadineQ43531006
A placebo-controlled, randomized, double-masked, variable dosage, clinical trial of azathioprine with and without methylprednisolone in multiple sclerosisQ43651803
The efficacy of inosine pranobex in preventing the acquired immunodeficiency syndrome in patients with human immunodeficiency virus infection. The Scandinavian Isoprinosine Study GroupQ45860274
Inosiplex and amyotrophic lateral sclerosis. Therapeutic trial in patients on Guam.Q54097797
Isoprinosine in treatment of acute viral encephalitisQ66703516
Cyclosporine versus azathioprine in the long-term treatment of multiple sclerosis--results of the German multicenter studyQ68127972
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectplaceboQ269829
placebo-controlled trialQ108853737
P304page(s)164-168
P577publication date1994-02-01
P1433published inJournal of Neurology, Neurosurgery and PsychiatryQ1599804
P1476titleA placebo-controlled trial of isoprinosine in patients with multiple sclerosis
P478volume57

Reverse relations

cites work (P2860)
Q39113644Associated Inosine to interferon: results of a clinical trial in multiple sclerosis.
Q35182733Clinical trials in progressive multiple sclerosis: lessons learned and future perspectives
Q41745131Current immunotherapy in multiple sclerosis
Q26782408Evaluation of Study and Patient Characteristics of Clinical Studies in Primary Progressive Multiple Sclerosis: A Systematic Review
Q92553174Inosine Pranobex: A Key Player in the Game Against a Wide Range of Viral Infections and Non-Infectious Diseases
Q33770448Magnetic resonance (MR) imaging as a marker for multiple sclerosis
Q72176233Neurology
Q36815380Novel oral agents for multiple sclerosis
Q33571873Outcomes assessment of drug treatment in multiple sclerosis clinical trials
Q29030703Primary progressive multiple sclerosis: current therapeutic strategies and future perspectives

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