| review article | Q7318358 |
| scholarly article | Q13442814 |
| P356 | DOI | 10.1016/S1074-7613(00)80087-4 |
| P8608 | Fatcat ID | release_e3gyaq375nebfdwwv3q4pz7gay |
| P698 | PubMed publication ID | 10485647 |
| P50 | author | Ken J. Ishii | Q30509977 |
| P2093 | author name string | Klinman DM | |
| Takeshita F | |||
| Verthelyi D | |||
| P2860 | cites work | Protection against malaria by immunization with plasmid DNA encoding circumsporozoite protein | Q24563514 |
| CpG motifs present in bacteria DNA rapidly induce lymphocytes to secrete interleukin 6, interleukin 12, and interferon gamma | Q24568172 | ||
| Sequence motifs in adenoviral DNA block immune activation by stimulatory CpG motifs | Q24644853 | ||
| Innate immunity: the virtues of a nonclonal system of recognition | Q29614428 | ||
| The medical threat of biological weapons | Q30233748 | ||
| The looming threat of bioterrorism | Q33536420 | ||
| CpG DNA can induce strong Th1 humoral and cell-mediated immune responses against hepatitis B surface antigen in young mice | Q33597242 | ||
| Bacterial CpG DNA activates immune cells to signal infectious danger. | Q33683211 | ||
| Immunization for Ebola virus infection | Q34065766 | ||
| CpG motifs in bacterial DNA trigger direct B-cell activation | Q34307394 | ||
| Immunostimulatory DNA sequences necessary for effective intradermal gene immunization | Q34384185 | ||
| Induction of cross-reactive anti-dsDNA antibodies in preautoimmune NZB/NZW mice by immunization with bacterial DNA. | Q35554410 | ||
| CpG oligodeoxynucleotides act as adjuvants that switch on T helper 1 (Th1) immunity | Q36380885 | ||
| Oligodeoxynucleotides enhance lipopolysaccharide-stimulated synthesis of tumor necrosis factor: dependence on phosphorothioate modification and reversal by heparin. | Q36437931 | ||
| Genetic to genomic vaccination | Q36872606 | ||
| Theoretical and experimental approaches to generalized autoimmunity | Q37783216 | ||
| Chlamydia infections and heart disease linked through antigenic mimicry | Q37878963 | ||
| CpG-DNA-specific activation of antigen-presenting cells requires stress kinase activity and is preceded by non-specific endocytosis and endosomal maturation | Q38331783 | ||
| Reduction of antigen expression from DNA vaccines by coadministered oligodeoxynucleotides | Q38333182 | ||
| Gene therapy by intramuscular injection of plasmid DNA: studies on firefly luciferase gene expression in mice | Q38566410 | ||
| Activation of human B cells by phosphorothioate oligodeoxynucleotides | Q39770135 | ||
| DNA methylation and its possible biological roles | Q40124163 | ||
| Subversion of the immune system by pathogens. | Q40807446 | ||
| Antisense oligonucleotides as therapeutic agents--is the bullet really magical? | Q40834751 | ||
| CpG DNA: a pathogenic factor in systemic lupus erythematosus? | Q40954780 | ||
| Immune responses to nucleic acid vaccines to rabies virus | Q41337967 | ||
| Innate immunity: impact on the adaptive immune response | Q41353080 | ||
| DNA immunization confers systemic, but not mucosal, protection against enteroinvasive bacteria | Q41483375 | ||
| Evaluation of the renal effects of an antisense phosphorothioate oligodeoxynucleotide in monkeys | Q41669806 | ||
| Type I interferon-mediated stimulation of T cells by CpG DNA | Q41824775 | ||
| Heterologous protection against influenza by injection of DNA encoding a viral protein | Q43828996 | ||
| DNA vaccines expressing either the GP or NP genes of Ebola virus protect mice from lethal challenge | Q44089592 | ||
| DNA-based immunization against hepatitis B virus | Q44567701 | ||
| Direct gene transfer into mouse muscle in vivo | Q44656494 | ||
| Humoral and cellular immunity to an encoded protein induced by direct DNA injection | Q44806502 | ||
| Macrophages sense pathogens via DNA motifs: induction of tumor necrosis factor-alpha-mediated shock | Q44931090 | ||
| CpG DNA, a novel immune enhancer for systemic and mucosal immunization with influenza virus | Q45754574 | ||
| Activity and safety of DNA plasmids encoding IL-4 and IFN gamma | Q45861110 | ||
| An improved plasmid DNA expression vector for direct injection into skeletal muscle | Q45878158 | ||
| Immunostimulatory DNA sequences function as T helper-1-promoting adjuvants. | Q45978807 | ||
| Immunostimulatory DNA is a potent mucosal adjuvant | Q46476023 | ||
| Induction of antigen-specific cytotoxic T lymphocytes in humans by a malaria DNA vaccine | Q47837811 | ||
| Plasmid DNA malaria vaccine: the potential for genomic integration after intramuscular injection | Q47845933 | ||
| Bacterial DNA and immunostimulatory CpG oligonucleotides trigger maturation and activation of murine dendritic cells | Q47915755 | ||
| Cellular cytotoxic response induced by DNA vaccination in HIV-1-infected patients | Q47918537 | ||
| Therapeutic applications of CpG-containing oligodeoxynucleotides | Q50131087 | ||
| Protection of chimpanzees from high-dose heterologous HIV-1 challenge by DNA vaccination. | Q52845358 | ||
| Induction of immune-mediated glomerulonephritis in normal mice immunized with bacterial DNA. | Q54651702 | ||
| Lessons from Iraq on bioweapons | Q58991132 | ||
| Bacterial DNA causes septic shock | Q59065014 | ||
| Immunostimulants | Q70477436 | ||
| Bacterial DNA induces murine interferon-gamma production by stimulation of interleukin-12 and tumor necrosis factor-alpha | Q70866576 | ||
| Amplification of antibody production by phosphorothioate oligodeoxynucleotides | Q71475786 | ||
| Cytokine gene expression in epidermis with biological effects following injection of naked DNA | Q71708643 | ||
| Manipulation of the immune response to a plasmid-encoded viral antigen by coinoculation with plasmids expressing cytokines | Q72641753 | ||
| Do DNA vaccines induce autoimmune disease? | Q73106011 | ||
| Expression of a viral protein by muscle cells in vivo induces protective cell-mediated immunity | Q73537545 | ||
| CpG-containing synthetic oligonucleotides promote B and cytotoxic T cell responses to protein antigen: a new class of vaccine adjuvants | Q73814892 | ||
| Modulation of amplitude and direction of in vivo immune responses by co-administration of cytokine gene expression cassettes with DNA immunogens | Q74442122 | ||
| CpG motifs as immune adjuvants | Q74607906 | ||
| Modulating the immune response to genetic immunization | Q77630763 | ||
| Protection against anthrax toxin by vaccination with a DNA plasmid encoding anthrax protective antigen | Q78164078 | ||
| P433 | issue | 2 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | bioterrorism | Q854975 |
| P304 | page(s) | 123-129 | |
| P577 | publication date | 1999-08-01 | |
| P1433 | published in | Immunity | Q6005457 |
| P1476 | title | Immune recognition of foreign DNA: a cure for bioterrorism? | |
| P478 | volume | 11 |
| Q24290668 | A Toll-like receptor recognizes bacterial DNA |
| Q37202396 | A role for NF-kappaB-dependent gene transactivation in sunburn. |
| Q28250104 | Adjuvant activity of CpG oligodeoxynucleotides |
| Q44565213 | Adjuvant effects of IL-1beta, IL-2, IL-8, IL-15, IFN-alpha, IFN-gamma TGF-beta4 and lymphotactin on DNA vaccination against Eimeria acervulina |
| Q40349551 | Anti-SARS-CoV immunity induced by a novel CpG oligodeoxynucleotide |
| Q36868322 | Antiinfective applications of toll-like receptor 9 agonists |
| Q27487859 | Broad-Spectrum Drugs Against Viral Agents |
| Q34592467 | Costimulation via lymphocyte function-associated antigen 1 in the absence of CD28 ligation promotes anergy of naive CD4+ T cells |
| Q35585084 | CpG DNA: Trigger of Sepsis, Mediator of Protection, or Both? |
| Q90055156 | CpG Oligonucleotides Protect Mice From Alphavirus Encephalitis: Role of NK Cells, Interferons, and TNF |
| Q35166828 | CpG motifs: the active ingredient in bacterial extracts? |
| Q34145320 | CpG oligodeoxynucleotides improve the survival of pregnant and fetal mice following Listeria monocytogenes infection. |
| Q38305300 | DNA-PKcs is required for activation of innate immunity by immunostimulatory DNA. |
| Q36228960 | Effect of CpG oligodeoxynucleotides on the immunogenicity of Pfs25, a Plasmodium falciparum transmission-blocking vaccine antigen |
| Q33957838 | Experimental therapy of filovirus infections |
| Q40752695 | Exposure to exogenous DNA can modify the sensitivity of the Fas apoptotic pathway |
| Q34556390 | HIV-1 Tat vaccines |
| Q35571281 | Immunoregulatory activity of CpG oligonucleotides in humans and nonhuman primates |
| Q53921727 | Immunostimulatory CpG oligodeoxynucleotides increase resistance against amoebic gill disease in Atlantic salmon, Salmo salar L. |
| Q34009351 | Induction of immune response in BALB/c mice with a DNA vaccine encoding bacterioferritin or P39 of Brucella spp. |
| Q35562180 | Innate immune activation as a broad-spectrum biodefense strategy Prospects and research challenges |
| Q36214504 | In Vivo Effect of Innate Immune Response Modulating Impurities on the Skin Milieu Using a Macaque Model: Impact on Product Immunogenicity |
| Q24522461 | Melioidosis: epidemiology, pathophysiology, and management |
| Q34785725 | Noncoding RNA danger motifs bridge innate and adaptive immunity and are potent adjuvants for vaccination |
| Q35165446 | Oral pretreatment of mice with CpG DNA reduces susceptibility to oral or intraperitoneal challenge with virulent Listeria monocytogenes |
| Q90288795 | Pharmacological modulation of nucleic acid sensors - therapeutic potential and persisting obstacles |
| Q36370825 | Potential role of phosphatidylinositol 3 kinase, rather than DNA-dependent protein kinase, in CpG DNA-induced immune activation |
| Q37157236 | Prodrugs for the treatment of neglected diseases. |
| Q38352474 | Ras participates in CpG oligodeoxynucleotide signaling through association with toll-like receptor 9 and promotion of interleukin-1 receptor-associated kinase/tumor necrosis factor receptor-associated factor 6 complex formation in macrophages |
| Q36941127 | TLR agonists regulate alloresponses and uncover a critical role for donor APCs in allogeneic bone marrow rejection |
| Q73458973 | The role of CpG motifs in innate immunity |
| Q74041131 | The role of the macrophage scavenger receptor in immune stimulation by bacterial DNA and synthetic oligonucleotides |
| Q74371034 | Therapeutic effects of BCG vaccination in adult asthmatic patients: a randomized, controlled trial |
| Q36501229 | Therapeutic potential of Toll-like receptor 9 activation |
| Q24811712 | Thermolytic CpG-containing DNA oligonucleotides as potential immunotherapeutic prodrugs |
| Q34717036 | Toll-like receptor adaptor molecules enhance DNA-raised adaptive immune responses against influenza and tumors through activation of innate immunity |
| Q42830856 | Transfection, but not retroviral transduction, upregulates apoptotic pathways in murine fibroblasts. |
| Q36171257 | Tweaking Innate Immunity: the Promise of Innate Immunologicals As Anti-infectives |
| Q35826404 | Use of CpG oligodeoxynucleotides as immune adjuvants |
| Q35790879 | Use of CpG oligodeoxynucleotides as immunoprotective agents |
| Q45012988 | Vaccination with DNA containing tat coding sequences and unmethylated CpG motifs protects cynomolgus monkeys upon infection with simian/human immunodeficiency virus (SHIV89.6P). |
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