DNA Methylation Dynamics and Cocaine in the Brain: Progress and Prospects

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DNA Methylation Dynamics and Cocaine in the Brain: Progress and Prospects is …
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scholarly articleQ13442814
review articleQ7318358

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P356DOI10.3390/GENES8050138
P932PMC publication ID5448012
P698PubMed publication ID28498318

P50authorDeborah MashQ545893
Gustavo TureckiQ3121397
Carl ErnstQ107855650
P2093author name stringKathryn Vaillancourt
P2860cites workAlterations in the morphology of dendrites and dendritic spines in the nucleus accumbens and prefrontal cortex following repeated treatment with amphetamine or cocaineQ48228519
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Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2Q22337290
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Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosineQ24614582
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MeCP2 binds to 5hmC enriched within active genes and accessible chromatin in the nervous system.Q40680118
Exposure to cocaine regulates inhibitory synaptic transmission in the nucleus accumbensQ40924471
Epigenomic Signatures of Neuronal Diversity in the Mammalian BrainQ41116966
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Neuronal activity modifies the chromatin accessibility landscape in the adult brainQ42319910
Cocaine-mediated downregulation of microglial miR-124 expression involves promoter DNA methylation.Q42975744
Effect of 5-aza-2-deoxycytidine microinjecting into hippocampus and prelimbic cortex on acquisition and retrieval of cocaine-induced place preference in C57BL/6 miceQ43020868
CDKL5 is a brain MeCP2 target gene regulated by DNA methylationQ43138683
Exploring the epigenetics of cocaine resistanceQ43741263
Effect of chronic heroin and cocaine administration on global DNA methylation in brain and liver.Q44521498
Decreased methylation of the NK3 receptor coding gene (TACR3) after cocaine-induced place preference in marmoset monkeysQ44862058
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Role of DNA methylation in the nucleus accumbens in incubation of cocaine cravingQ47647657
Prenatal cocaine exposure impairs cognitive function of progeny via insulin growth factor II epigenetic regulationQ47692726
Differential regulation of MeCP2 and PP1 in passive or voluntary administration of cocaine or foodQ47758281
S-adenosylmethionine modifies cocaine-induced DNA methylation and increases locomotor sensitization in miceQ48007297
MeCP2 and the enigmatic organization of brain chromatin. Implications for depression and cocaine addictionQ26747013
Extra-coding RNAs regulate neuronal DNA methylation dynamicsQ27339453
CTCF-promoted RNA polymerase II pausing links DNA methylation to splicingQ28249503
Subregional, dendritic compartment, and spine subtype specificity in cocaine regulation of dendritic spines in the nucleus accumbensQ28266784
Phosphorylation of DARPP-32 at Threonine-34 is required for cocaine actionQ28269125
Neuronal and behavioural abnormalities in striatal function in DARPP-32-mutant miceQ28372752
Gene expression changes in the medial prefrontal cortex and nucleus accumbens following abstinence from cocaine self-administrationQ28394162
Gene expression in human hippocampus from cocaine abusers identifies genes which regulate extracellular matrix remodelingQ28471583
Reversal of cocaine-conditioned place preference through methyl supplementation in mice: altering global DNA methylation in the prefrontal cortexQ28481559
Cocaine represses protein phosphatase-1Cβ through DNA methylation and Methyl-CpG Binding Protein-2 recruitment in adult rat brainQ28565994
Fluoxetine and cocaine induce the epigenetic factors MeCP2 and MBD1 in adult rat brainQ28579363
MeCP2 controls BDNF expression and cocaine intake through homeostatic interactions with microRNA-212.Q28909710
A translational profiling approach for the molecular characterization of CNS cell typesQ29615252
Conserved role of intragenic DNA methylation in regulating alternative promotersQ29616289
Brain-specific phosphorylation of MeCP2 regulates activity-dependent Bdnf transcription, dendritic growth, and spine maturationQ29616327
Methylation-induced repression--belts, braces, and chromatinQ29617487
Global epigenomic reconfiguration during mammalian brain developmentQ29617800
Linking DNA methylation and histone modification: patterns and paradigmsQ29617801
Chromatin modification and epigenetic reprogramming in mammalian developmentQ29617802
Distribution, recognition and regulation of non-CpG methylation in the adult mammalian brainQ30433875
DNA methylation regulates cocaine-induced behavioral sensitization in miceQ30498534
Epigenetic inheritance of a cocaine-resistance phenotypeQ30530759
Ontological analysis of gene expression data: current tools, limitations, and open problemsQ30993399
Maternal cocaine administration in mice alters DNA methylation and gene expression in hippocampal neurons of neonatal and prepubertal offspringQ33326645
PcG proteins, DNA methylation, and gene repression by chromatin looping.Q33389249
Developmental and behavioral consequences of prenatal cocaine exposure: a reviewQ34083725
MeCP2 in the nucleus accumbens contributes to neural and behavioral responses to psychostimulantsQ34086410
Dnmt3a regulates emotional behavior and spine plasticity in the nucleus accumbensQ34086476
Dnmt3a and Dnmt1 functionally cooperate during de novo methylation of DNA.Q34154656
Regulation of transcription and chromatin by methyl-CpG binding protein MBD1.Q34460587
Reprogrammable CRISPR/Cas9-based system for inducing site-specific DNA methylation.Q34526213
Cocaine and the AP-1 transcription factor complexQ34749449
Substance-specific and shared transcription and epigenetic changes in the human hippocampus chronically exposed to cocaine and alcoholQ34836140
Differences in DNA methylation between human neuronal and glial cells are concentrated in enhancers and non-CpG sitesQ34993956
IL-4/IL-13-dependent and independent expression of miR-124 and its contribution to M2 phenotype of monocytic cells in normal conditions and during allergic inflammationQ35072554
Neuronal MeCP2 is expressed at near histone-octamer levels and globally alters the chromatin state.Q35114553
Cocaine increases phosphorylation of MeCP2 in the rat striatum in vivo: a differential role of NMDA receptorsQ35223882
5-Hydroxymethylcytosine is a predominantly stable DNA modification.Q35244114
Methyl supplementation attenuates cocaine-seeking behaviors and cocaine-induced c-Fos activation in a DNA methylation-dependent mannerQ35707940
Characterizing 5-hydroxymethylcytosine in human prefrontal cortex at single base resolutionQ35763026
Substantial DNA methylation differences between two major neuronal subtypes in human brainQ35854307
Forced Abstinence from Cocaine Self-Administration is Associated with DNA Methylation Changes in Myelin Genes in the Corpus Callosum: a Preliminary StudyQ36031125
Role of Tet1 and 5-hydroxymethylcytosine in cocaine actionQ36197525
Genome-wide base-resolution mapping of DNA methylation in single cells using single-cell bisulfite sequencing (scBS-seq).Q36275051
Widespread promoter methylation of synaptic plasticity genes in long-term potentiation in the adult brain in vivo.Q36320826
The role of mammalian DNA methyltransferases in the regulation of gene expression.Q36338053
Gene expression profile of the nucleus accumbens of human cocaine abusers: evidence for dysregulation of myelinQ36408206
TET-catalyzed oxidation of intragenic 5-methylcytosine regulates CTCF-dependent alternative splicingQ36543721
Correspondence of DNA Methylation Between Blood and Brain Tissue and Its Application to Schizophrenia ResearchQ36579945
Demethylation of c-MYB binding site mediates upregulation of Bdnf IV in cocaine-conditioned place preferenceQ36615988
DNA Methylation in Memory Formation: Emerging InsightsQ36629627
Identification of long noncoding RNAs dysregulated in the midbrain of human cocaine abusersQ36795258
Persistent variations in neuronal DNA methylation following cocaine self-administration and protracted abstinence in mice.Q36921311
The role of active DNA demethylation and Tet enzyme function in memory formation and cocaine actionQ36995366
Expression of transcripts for myelin related genes in postmortem brain from cocaine abusersQ37042476
Single-cell genome-wide bisulfite sequencing uncovers extensive heterogeneity in the mouse liver methylomeQ37067909
Repurposing the CRISPR-Cas9 system for targeted DNA methylationQ37076267
CRISPR-dCas9 mediated TET1 targeting for selective DNA demethylation at BRCA1 promoter.Q37564798
Activity-dependent calcium signaling and ERK-MAP kinases in neurons: a link to structural plasticity of the nucleus and gene transcription regulation.Q37821580
Emerging roles of TET proteins and 5-hydroxymethylcytosines in active DNA demethylation and beyondQ37910671
The evidence for functional non-CpG methylation in mammalian cellsQ38203384
New concepts in DNA methylationQ38221707
Dopamine reuptake transporter (DAT) "inverse agonism"--a novel hypothesis to explain the enigmatic pharmacology of cocaineQ38222327
Function and information content of DNA methylationQ38319920
The alternative role of DNA methylation in splicing regulationQ38402670
Methyl-CpG-Binding Protein (MBD) Family: Epigenomic Read-Outs Functions and Roles in Tumorigenesis and Psychiatric Diseases.Q38553124
Transgenerational epigenetic inheritance: an open discussionQ38582112
Neuronal activity modifies the DNA methylation landscape in the adult brainQ38594616
Inhibition of DNA methyltransferases regulates cocaine self-administration by rats: a genome-wide DNA methylation studyQ39268218
In vivo activity of murine de novo methyltransferases, Dnmt3a and Dnmt3bQ39449285
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue5
P921main subjectDNA methylationQ874745
P577publication date2017-05-12
P1433published inGenesQ5532699
P1476titleDNA Methylation Dynamics and Cocaine in the Brain: Progress and Prospects
P478volume8

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cites work (P2860)
Q90643182AgeGuess, a Methylomic Prediction Model for Human Ages
Q100526145Cocaine-related DNA methylation in caudate neurons alters 3D chromatin structure of the IRXA gene cluster
Q49912035Environmental, genetic and epigenetic contributions to cocaine addiction
Q104509567Exposure to different early-life stress experiences results in differentially altered DNA methylation in the brain and immune system
Q92212835Genome-wide DNA methylation profile in the peripheral blood of cocaine and crack dependents
Q60636106MiR-9, miR-153 and miR-124 are down-regulated by acute exposure to cocaine in a dopaminergic cell model and may contribute to cocaine dependence
Q57133609Molecular Genetics and New Medication Strategies for Opioid Addiction
Q91829800OPRM1 A118G Polymorphisms and Its Role in Opioid Addiction: Implication on Severity and Treatment Approaches
Q99413708Regulation of dopamine-dependent transcription and cocaine action by Gadd45b
Q92849587The Molecular Basis of Drug Addiction: Linking Epigenetic to Synaptic and Circuit Mechanisms

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