scholarly article | Q13442814 |
review article | Q7318358 |
P356 | DOI | 10.1016/S1367-5931(99)00007-1 |
P698 | PubMed publication ID | 10508675 |
P50 | author | Janet Thornton | Q6153626 |
Christine Orengo | Q21572185 | ||
P2093 | author name string | Todd AE | |
P2860 | cites work | Structural comparisons of TIM barrel proteins suggest functional and evolutionary relationships between beta-galactosidase and other glycohydrolases | Q30175782 |
alpha/beta barrel evolution and the modular assembly of enzymes: emerging trends in the flavin oxidase/dehydrogenase family | Q30194547 | ||
Three-dimensional structure of the bifunctional enzyme N-(5'-phosphoribosyl)anthranilate isomerase-indole-3-glycerol-phosphate synthase from Escherichia coli | Q30196182 | ||
From protein structure to function. | Q30322099 | ||
DOMPLOT: a program to generate schematic diagrams of the structural domain organization within proteins, annotated by ligand contacts. | Q30322162 | ||
Analogous enzymes: independent inventions in enzyme evolution | Q32028978 | ||
Moonlighting proteins. | Q33543960 | ||
An evolutionary treasure: unification of a broad set of amidohydrolases related to urease | Q34425600 | ||
Convergent evolution of Trichomonas vaginalis lactate dehydrogenase from malate dehydrogenase | Q37204360 | ||
On the origin of enzymatic species | Q40787968 | ||
Evolutionary divergence of substrate specificity within the chymotrypsin-like serine protease fold | Q41646804 | ||
Understanding enzyme superfamilies. Chemistry As the fundamental determinant in the evolution of new catalytic activities | Q41655286 | ||
From fold predictions to function predictions: automation of functional site conservation analysis for functional genome predictions | Q41666691 | ||
Derivation of 3D coordinate templates for searching structural databases: application to Ser-His-Asp catalytic triads in the serine proteinases and lipases | Q42136534 | ||
CORA--topological fingerprints for protein structural families | Q42847036 | ||
The enolase superfamily: a general strategy for enzyme-catalyzed abstraction of the alpha-protons of carboxylic acids | Q44192562 | ||
Protein folds and functions | Q47625259 | ||
The recruitment of crystallins: new functions precede gene duplication. | Q52236837 | ||
Mechanistically diverse enzyme superfamilies: the importance of chemistry in the evolution of catalysis | Q56902483 | ||
Role of enzyme-substrate flexibility in catalytic activity: an evolutionary perspective | Q56902495 | ||
From genome sequences to protein function | Q56918719 | ||
The enzyme lactate dehydrogenase as a structural protein in avian and crocodilian lenses | Q59056658 | ||
Crystal structure of human α-lactalbumin at 1·7 Å resolution | Q60304615 | ||
What we do not know about sequence analysis and sequence databases | Q60309515 | ||
Domain assignment for protein structures using a consensus approach: characterization and analysis | Q24673293 | ||
Structure of the adenylation domain of an NAD+-dependent DNA ligase | Q27618601 | ||
Crystal structure of D-amino acid oxidase: a case of active site mirror-image convergent evolution with flavocytochrome b2 | Q27733284 | ||
Determinants of substrate specificity in the superfamily of amino acid dehydrogenases | Q27748444 | ||
Crystallographic study of steps along the reaction pathway of D-amino acid aminotransferase | Q27749055 | ||
The crystal structure of benzoylformate decarboxylase at 1.6 A resolution: diversity of catalytic residues in thiamin diphosphate-dependent enzymes | Q27764622 | ||
Evolution of an enzyme active site: the structure of a new crystal form of muconate lactonizing enzyme compared with mandelate racemase and enolase | Q27765259 | ||
Evolution of enzymatic activities in the enolase superfamily: crystal structure of (D)-glucarate dehydratase from Pseudomonas putida | Q27765687 | ||
Redesigning the substrate specificity of an enzyme by cumulative effects of the mutations of non-active site residues | Q27766665 | ||
SCOP: a structural classification of proteins database for the investigation of sequences and structures | Q27860689 | ||
The Protein Data Bank: a computer-based archival file for macromolecular structures | Q27860989 | ||
CATH--a hierarchic classification of protein domain structures | Q27861100 | ||
The relationship between protein structure and function: a comprehensive survey with application to the yeast genome | Q28144049 | ||
The alpha/beta hydrolase fold | Q28156084 | ||
Gene duplications in the structural evolution of chymotrypsin | Q28239251 | ||
Protein superfamilies and domain superfolds | Q28242652 | ||
One thousand families for the molecular biologist | Q28266140 | ||
The anatomy and taxonomy of protein structure | Q28277011 | ||
Predicting function: from genes to genomes and back | Q28286883 | ||
The molecular biology of multidomain proteins. Selected examples | Q28289043 | ||
Comparative anatomy of the aldo-keto reductase superfamily | Q30043211 | ||
P433 | issue | 5 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | protein evolution | Q59870539 |
P304 | page(s) | 548-556 | |
P577 | publication date | 1999-10-01 | |
P1433 | published in | Current Opinion in Chemical Biology | Q15758415 |
P1476 | title | Evolution of protein function, from a structural perspective | |
P478 | volume | 3 |
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