scholarly article | Q13442814 |
review article | Q7318358 |
P356 | DOI | 10.1097/00006534-199910000-00031 |
P698 | PubMed publication ID | 10513931 |
P2093 | author name string | J Schalkwijk | |
M Kon | |||
F B Niessen | |||
P H Spauwen | |||
P433 | issue | 5 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 1435-1458 | |
P577 | publication date | 1999-10-01 | |
P1433 | published in | Plastic and Reconstructive Surgery | Q7202071 |
P1476 | title | On the nature of hypertrophic scars and keloids: a review | |
P478 | volume | 104 |
Q50220929 | A Selenium-Enriched Ziyang Green Tea Polysaccharide Induces Bax-Dependent Mitochondrial Apoptosis and Inhibits TGF-β1-Stimulated Collagen Expression in Human Keloid Fibroblasts via NG2 Inactivation |
Q41966853 | A mathematical model for the simulation of the formation and the subsequent regression of hypertrophic scar tissue after dermal wounding. |
Q35884665 | A phase I/II trial of intraoperative breast radiotherapy in an Asian population: 5-year results of local control and cosmetic outcome |
Q35167749 | Ablative fractional photothermolysis for the treatment of hypertrophic burn scars in adult and pediatric patients: a single surgeon's experience |
Q34743644 | Acquired ear defects |
Q45870472 | Adenovirus-relaxin gene therapy for keloids: implication for reversing pathological fibrosis |
Q37145666 | Adipose tissue-derived stem cells suppress hypertrophic scar fibrosis via the p38/MAPK signaling pathway |
Q35100920 | Admixture mapping identifies a locus at 15q21.2-22.3 associated with keloid formation in African Americans. |
Q61806854 | Advances in the treatment of traumatic scars with laser, intense pulsed light, radiofrequency, and ultrasound |
Q35567201 | An abnormality in glucocorticoid receptor expression differentiates steroid responders from nonresponders in keloid disease |
Q28539207 | Anti-fibrotic actions of interleukin-10 against hypertrophic scarring by activation of PI3K/AKT and STAT3 signaling pathways in scar-forming fibroblasts |
Q92874811 | Antifibrotic Effects of High-Mobility Group Box 1 Protein Inhibitor (Glycyrrhizin) on Keloid Fibroblasts and Keloid Spheroids through Reduction of Autophagy and Induction of Apoptosis |
Q37256095 | Antimitotic drug injections and radiotherapy: a review of the effectiveness of treatment for hypertrophic scars and keloids |
Q34282426 | Apoptotic cell death induced by 5-aminolaevulinic acid-mediated photodynamic therapy of hypertrophic scar-derived fibroblasts |
Q33265273 | Application of mitomycin-C for head and neck keloids |
Q52664018 | Autologous chyle fat grafting for the treatment of hypertrophic scars and scar-related conditions. |
Q88811634 | Autologous fat grafting in keloids and hypertrophic scars: a review |
Q34655676 | Biological effects of silicone gel sheeting |
Q51222223 | Challenging the dogma: relationship between time to healing and formation of hypertrophic scars after burn injuries. |
Q35118003 | Chemokine and chemokine receptor expression in keloid and normal fibroblasts |
Q26778684 | Chemokines in Wound Healing and as Potential Therapeutic Targets for Reducing Cutaneous Scarring |
Q90396394 | Chondroitin Sulfate Promotes the Proliferation of Keloid Fibroblasts Through Activation of the Integrin and Protein Kinase B Pathways |
Q38260546 | Chondroitinase: A promising therapeutic enzyme |
Q37606506 | Clinical analysis of auricular benign masses |
Q37606792 | Clinical characteristics of auricular keloids treated with surgical excision |
Q53416611 | Clinical characteristics of facial keloids treated with surgical excision followed by intra- and postoperative intralesional steroid injections. |
Q43239163 | Collagen and Elastic Fiber Content Correlation Analysis between Horizontal and Vertical Orientations of Skin Samples of Human Body |
Q39707326 | Collagen bundle morphometry in skin and scar tissue: a novel distance mapping method provides superior measurements compared to Fourier analysis |
Q54365116 | Collagen triple helix repeat containing-1 inhibits transforming growth factor-b1-induced collagen type I expression in keloid. |
Q50097019 | Comparative evaluations of hypertrophic scar formation in in vivo models |
Q43168514 | Comparison of Intralesional Triamcinolone Acetonide, 5-Fluorouracil, and Their Combination for the Treatment of Keloids. |
Q97422458 | Comparison of hypertrophic scarring on a red Duroc pig and a Guangxi Mini Bama pig |
Q34340623 | Complications, salvage, and enhancement of local flaps in facial reconstruction |
Q51497321 | Conditioned medium from keloid keratinocyte/keloid fibroblast coculture induces contraction of fibroblast-populated collagen lattices. |
Q46078757 | Correction of complex facial scars |
Q90168909 | Cuprous oxide nanoparticles reduces hypertrophic scarring by inducing fibroblast apoptosis |
Q28709996 | Curative effects of oleanolic Acid on formed hypertrophic scars in the rabbit ear model |
Q39414298 | Current Therapeutic Approach to Hypertrophic Scars |
Q34092764 | Custom made pressure appliance for presurgical sustained compression of auricular keloid |
Q42149285 | Decorin-expressing adenovirus decreases collagen synthesis and upregulates MMP expression in keloid fibroblasts and keloid spheroids. |
Q47117290 | Decoy Wnt receptor (sLRP6E1E2)-expressing adenovirus induces anti-fibrotic effect via inhibition of Wnt and TGF-β signaling |
Q34694012 | Deep dermal fibroblast profibrotic characteristics are enhanced by bone marrow-derived mesenchymal stem cells |
Q55076212 | Determination of Spearman Correlation Coefficient (r) to Evaluate the Linear Association of Dermal Collagen and Elastic Fibers in the Perspectives of Skin Injury. |
Q35657756 | Development of a Best Evidence Statement for the Use of Pressure Therapy for Management of Hypertrophic Scarring |
Q47897523 | Different properties of skin of different body sites: The root of keloid formation? |
Q87259420 | Differential item functioning in the Observer Scale of the POSAS for different scar types |
Q39227149 | Differentiation of human embryonic stem cells into clinically amenable keratinocytes in an autogenic environment. |
Q55318930 | Distensibility and Gross Elasticity of the Skin at Various Body Sites and Association with Pathological Scarring: A Case Study. |
Q93055411 | Downregulation of CFTR Is Involved in the Formation of Hypertrophic Scars |
Q50557422 | Downregulation of β-catenin blocks fibrosis via Wnt2 signaling in human keloid fibroblasts. |
Q26827377 | Ear keloids: a review and update of treatment options |
Q37639780 | Effect of Extracts of Terminalia chebula on Proliferation of Keratinocytes and Fibroblasts Cells: An Alternative Approach for Wound Healing. |
Q51761606 | Effect of transforming growth factor-beta1 antisense oligonucleotides on matrix metalloproteinases and their inhibitors in keloid fibroblasts. |
Q36177977 | Effectiveness of onion extract gel on surgical scars in asians |
Q38981579 | Effects of lentiviral vector-mediated TRADD expression on the inhibition of hypertrophic scar formation |
Q51736672 | Effects of zafirlukast on capsular contracture: controlled study measuring the mammary compliance. |
Q51282357 | Effects of zafirlukast on capsular contracture: long-term results. |
Q30564100 | Efficacy and safety of an advanced formula silicone gel for prevention of post-operative scars |
Q92871317 | Efficacy of surgical excision and sub-dermal injection of triamcinolone acetonide for treatment of keloid scars after caesarean section: a single blind randomised controlled trial protocol |
Q45400761 | Elevated expression of pleiotrophin in human hypertrophic scars |
Q36407401 | Emerging new drugs for scar reduction |
Q33871524 | Endoscope-assisted submandibular sialadenectomy: a review of outcomes, complications, and ethical concerns. |
Q53556234 | Endothelial-to-mesenchymal transition induced by Wnt 3a in keloid pathogenesis. |
Q34834931 | Enhanced in vivo delivery of 5-fluorouracil by ethosomal gels in rabbit ear hypertrophic scar model |
Q43492054 | Epidemiology of keloids in normally pigmented Africans and African people with albinism: population-based cross-sectional survey |
Q38343232 | Epigenetically altered wound healing in keloid fibroblasts. |
Q53482048 | Epithelial-mesenchymal transition in keloid tissues and TGF-β1-induced hair follicle outer root sheath keratinocytes. |
Q84978364 | Essential oil from rhizomes ofLigusticum chuanxionginduces apoptosis in hypertrophic scar fibroblasts |
Q40443087 | Etk/Bmx mediates expression of stress-induced adaptive genes VEGF, PAI-1, and iNOS via multiple signaling cascades in different cell systems |
Q24295163 | Expression of keratin K2e in cutaneous and oral lesions: association with keratinocyte activation, proliferation, and keratinization |
Q45095856 | Extract of Aneilema keisak inhibits transforming growth factor-β-dependent signalling by inducing Smad2 downregulation in keloid fibroblasts |
Q38217742 | Extramarginal excision is preferable for hypertrophic scars. |
Q54312563 | FK506 inhibits the enhancing effects of transforming growth factor (TGF)-β1 on collagen expression and TGF-β/Smad signalling in keloid fibroblasts: implication for new therapeutic approach. |
Q35085228 | Fibroproliferative scars |
Q35167479 | Follicular and scarring disorders in skin of color: presentation and management |
Q35583617 | From scarless fetal wounds to keloids: Molecular studies in wound healing |
Q51584092 | Gene expression patterns in isolated keloid fibroblasts. |
Q34102567 | Gene profiling of keloid fibroblasts shows altered expression in multiple fibrosis-associated pathways. |
Q53702016 | Gene-based evaluation of low-frequency variation and genetically-predicted gene expression impacting risk of keloid formation. |
Q47981027 | Genetic susceptibility to keloid disease: transforming growth factor beta receptor gene polymorphisms are not associated with keloid disease |
Q34648643 | Genome-wide analysis using exon arrays demonstrates an important role for expression of extra-cellular matrix, fibrotic control and tissue remodelling genes in Dupuytren's disease |
Q53549097 | Going into surgery: Risk factors for hypertrophic scarring. |
Q97526646 | Healing of Bilateral Nipple Areolar Complex Necrosis by Secondary Intention |
Q34911441 | Heat shock proteins modulate keloid formation |
Q41076354 | Hepatocyte growth factor-expressing adenovirus upregulates matrix metalloproteinase-1 expression in keloid fibroblasts. |
Q37310602 | Hepatoma-derived growth factor and its role in keloid pathogenesis |
Q88512371 | High-resolution ultrasound in the diagnosis of trigger finger and evaluation of response to steroid injection |
Q26863376 | Human hypertrophic and keloid scar models: principles, limitations and future challenges from a tissue engineering perspective |
Q50952143 | Hydrated keratinocytes reduce collagen synthesis by fibroblasts via paracrine mechanisms. |
Q58564522 | Hyperbaric oxygen therapy improves the effect of keloid surgery and radiotherapy by reducing the recurrence rate |
Q90481973 | Hyperbaric oxygen therapy relieved pruritus and pain of keloid patients |
Q48345496 | Hypertrophic Scars: Are Vitamins and Inflammatory Biomarkers Related with the Pathophysiology of Wound Healing? |
Q24595036 | Hypertrophic scarring and keloids: pathomechanisms and current and emerging treatment strategies |
Q36154218 | Hypertrophic scarring: the greatest unmet challenge after burn injury |
Q33522033 | Hypertrophic versus non hypertrophic scars compared by immunohistochemistry and laser confocal microscopy: type I and III collagens |
Q36774975 | IL10 inhibits starvation-induced autophagy in hypertrophic scar fibroblasts via cross talk between the IL10-IL10R-STAT3 and IL10-AKT-mTOR pathways |
Q28542693 | In vivo early intervention and the therapeutic effects of 20(s)-ginsenoside rg3 on hypertrophic scar formation |
Q49038651 | Increased epidermal thickness and abnormal epidermal differentiation in keloid scars |
Q51726035 | Inhibited early immunologic response is associated with hypertrophic scarring. |
Q53192719 | Inhibitory effect of TGF-β peptide antagonist on the fibrotic phenotype of human hypertrophic scar fibroblasts. |
Q26800421 | Intralesional Cryotherapy for the Treatment of Keloid Scars: Evaluating Effectiveness |
Q84973959 | Intralesional Injection of Corticosteroids: A Lesson from Liposuction |
Q48211919 | Intralesional botulinum toxin type A equally effective and better tolerated than intralesional steroid in the treatment of keloids: a randomized controlled trial |
Q88811725 | Intralesional cryotherapy for hypertrophic scars and keloids: a review |
Q37426269 | Intralesional cryotherapy versus excision and corticosteroids or brachytherapy for keloid treatment: study protocol for a randomised controlled trial. |
Q35964625 | Intralesional injection of adipose-derived stem cells reduces hypertrophic scarring in a rabbit ear model |
Q38687388 | Investigating histological aspects of scars in children |
Q35957187 | Investigating the potential of Shikonin as a novel hypertrophic scar treatment |
Q53300940 | Keloid explant culture: a model for keloid fibroblasts isolation and cultivation based on the biological differences of its specific regions |
Q39977027 | Keloid formation after syndactyly release in patients with associated macrodactyly: management with methotrexate therapy |
Q33526081 | Keloid scarring: new treatments ahead. |
Q51375703 | Keloid-derived fibroblasts show increased secretion of factors involved in collagen turnover and depend on matrix metalloproteinase for migration. |
Q35928377 | Keloids and Hypertrophic Scars: A Spectrum of Clinical Challenges. |
Q92063767 | Keloids: A Review of Etiology, Prevention, and Treatment |
Q33910210 | Keloids: Pathogenesis, Clinical Features, and Management |
Q34512378 | Keloids: The paradigm of skin fibrosis - Pathomechanisms and treatment |
Q57892259 | Keratinocyte-derived growth factors play a role in the formation of hypertrophic scars |
Q33944720 | Laser and intense pulsed light therapy for the treatment of hypertrophic scars: a systematic review |
Q88811718 | Lasers and ancillary treatments for scar management Part 2: Keloid, hypertrophic, pigmented and acne scars |
Q35718769 | Levels of Evidence in the Plastic Surgery Literature: A Citation Analysis of the Top 50 'Classic' Papers |
Q36784280 | Low-dose enalapril in the treatment of surgical cutaneous hypertrophic scar and keloid--two case reports and literature review. |
Q50054263 | Lower energy radial shock wave therapy improves characteristics of hypertrophic scar in a rabbit ear model |
Q33871617 | Management of chest keloids |
Q48016975 | Management of external ear keloids using form-pressure therapy |
Q34699606 | Management of keloids and hypertrophic scars: current and emerging options |
Q37150483 | Matrix control of scarring. |
Q55036724 | Medical Needling: Effect on Moisture and Transepidermal Water Loss of Mature Hypertrophic Burn Scars. |
Q37233314 | MiR-21-5p Links Epithelial-Mesenchymal Transition Phenotype with Stem-Like Cell Signatures via AKT Signaling in Keloid Keratinocytes |
Q35251059 | MicroRNA 181b regulates decorin production by dermal fibroblasts and may be a potential therapy for hypertrophic scar |
Q47836814 | MicroRNA-192 regulates hypertrophic scar fibrosis by targeting SIP1. |
Q50054021 | MicroRNA-222 regulates the viability of fibroblasts in hypertrophic scars via matrix metalloproteinase 1. |
Q37720186 | MicroRNA‑185 regulates transforming growth factor‑β1 and collagen‑1 in hypertrophic scar fibroblasts |
Q43176471 | Morphine enhances tissue content of collagen and increases wound tensile strength |
Q50224711 | Morphological alterations of the tendon and pulley on ultrasound after intrasynovial injection of betamethasone for trigger digit. |
Q37228125 | N-(2-Aminoethyl) Ethanolamine-Induced Morphological, Biochemical, and Biophysical Alterations in Vascular Matrix Associated With Dissecting Aortic Aneurysm |
Q42679272 | Naringenin attenuates fibroblast activation and inflammatory response in a mechanical stretch-induced hypertrophic scar mouse model |
Q33193109 | New Therapies for the Management of Keloids |
Q93196211 | Nintedanib inhibits keloid fibroblast functions by blocking the phosphorylation of multiple kinases and enhancing receptor internalization |
Q37016359 | Observations on the procedural aspects and health effects of scarification in sub-Saharan Africa |
Q34071435 | Operative treatment of functional facial skin disorders |
Q33749141 | Overview of surgical scar prevention and management. |
Q51537407 | Peripheral nerve regeneration in the MRL/MpJ ear wound model. |
Q38128386 | Pharmacological treatment for keloids |
Q35650161 | Phase and Texture Characterizations of Scar Collagen Second-Harmonic Generation Images Varied with Scar Duration |
Q26779081 | Pleiotropic Effects of Immune Responses Explain Variation in the Prevalence of Fibroproliferative Diseases |
Q49358311 | Polymerization-Induced Phase Separation Formation of Structured Hydrogel Particles via Microfluidics for Scar Therapeutics. |
Q34655684 | Pressure therapy to treat burn scars |
Q38467096 | Protein-protein interaction network of gene expression in the hydrocortisone-treated keloid |
Q37292100 | Proteomic profiling reveals upregulated protein expression of hsp70 in keloids. |
Q33881965 | Quantification of scar margin in keloid different from atrophic scar by multiphoton microscopic imaging |
Q42915587 | Quantitative fraction evaluation of dermal collagen and elastic fibres in the skin samples obtained in two orientations from the trunk region |
Q35193572 | RUNX3 expression is associated with sensitivity to pheophorbide a-based photodynamic therapy in keloids. |
Q36083833 | Radiation Therapy Following Total Keloidectomy: A Retrospective Study over 11 Years |
Q24202117 | Radiotherapy and corticosteroids for preventing and treating keloid scars |
Q38268118 | Recent developments in the use of intralesional injections keloid treatment |
Q58108075 | Reconstructed human keloid models show heterogeneity within keloid scars |
Q45842108 | Reverse activated hyrax pressure appliance for treatment of a keloid located at auricula helix |
Q35480534 | Role of CD14 and TLR4 in type I, type III collagen expression, synthesis and secretion in LPS-induced normal human skin fibroblasts |
Q40666079 | Role of IGF system of mitogens in the induction of fibroblast proliferation by keloid-derived keratinocytes in vitro |
Q35834700 | Role of adjuvant radiotherapy in recurrent earlobe keloids |
Q35055573 | Salinomycin and other polyether ionophores are a new class of antiscarring agent |
Q36319281 | Scar evaluation and management: recommendations |
Q38649653 | Scar management in burn injuries using drug delivery and molecular signaling: Current treatments and future directions |
Q39126412 | Silk-fibroin-coated liposomes for long-term and targeted drug delivery |
Q24527236 | Skin scarring |
Q99237674 | Skin substitutes are more potent than dermal or epidermal substitutes in stimulating endothelial cell sprouting |
Q90600884 | Smad interacting protein 1 influences transforming growth factor-β1/Smad signaling in extracellular matrix protein production and hypertrophic scar formation |
Q36620519 | Smad ubiquitination regulatory factor 2 expression is enhanced in hypertrophic scar fibroblasts from burned children |
Q37314221 | Sorafenib exerts an anti-keloid activity by antagonizing TGF-β/Smad and MAPK/ERK signaling pathways |
Q34621935 | Spontaneous keloids: about a rare case |
Q38663516 | Stem Cell-Based Therapeutics to Improve Wound Healing. |
Q88811669 | Steroid tape: A promising adjunct to scar management |
Q35010481 | Strategic management of keloid disease in ethnic skin: a structured approach supported by the emerging literature. |
Q93272826 | Strategies to prevent hypertrophic scar formation: a review of therapeutic interventions based on molecular evidence |
Q37663312 | Studying intense pulsed light method along with corticosteroid injection in treating keloid scars. |
Q40290392 | Successful eradication of helical rim keloids with surgical excision followed by pressure therapy using a combination of magnets and silicone gel sheeting |
Q42438679 | Suppression of insulin-like growth factor signalling pathway and collagen expression in keloid-derived fibroblasts by quercetin: its therapeutic potential use in the treatment and/or prevention of keloids |
Q26795383 | Surgical Excision with Adjuvant Irradiation for Treatment of Keloid Scars: A Systematic Review |
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