Characterization of a highly glycosylated form of the human cytomegalovirus HLA class I homologue gpUL18

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Characterization of a highly glycosylated form of the human cytomegalovirus HLA class I homologue gpUL18 is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1099/VIR.0.81126-0
P932PMC publication ID2844262
P698PubMed publication ID16227221
P5875ResearchGate publication ID7539602

P50authorEddie C. WangQ71829139
Gavin WilkinsonQ92228749
Brian P McSharryQ40125848
P2093author name stringCarole Rickards
Cora Griffin
Peter Tomasec
Helena Browne
P2860cites workULBPs, novel MHC class I-related molecules, bind to CMV glycoprotein UL16 and stimulate NK cytotoxicity through the NKG2D receptorQ24290906
A novel immunoglobulin superfamily receptor for cellular and viral MHC class I moleculesQ24309285
Cytomegalovirus induces sialyl Lewis(x) and Lewis(x) on human endothelial cellsQ73669757
Impaired spontaneous endocytosis of HLA-GQ73878090
Differential N-linked glycosylation of human immunodeficiency virus and Ebola virus envelope glycoproteins modulates interactions with DC-SIGN and DC-SIGNRQ24541155
Downregulation of natural killer cell-activating ligand CD155 by human cytomegalovirus UL141Q24616413
Human inhibitory receptors Ig-like transcript 2 (ILT2) and ILT4 compete with CD8 for MHC class I binding and bind preferentially to HLA-GQ24678795
Crystal structure of HLA-A2 bound to LIR-1, a host and viral major histocompatibility complex receptorQ27641776
Functional characterization of HLA-F and binding of HLA-F tetramers to ILT2 and ILT4 receptorsQ28199758
Molecular cloning, functional expression, and signaling characteristics of a C-C chemokine receptorQ28297700
Evasion of cellular antiviral responses by human cytomegalovirus TRS1 and IRS1Q33195896
The inhibitory receptor LIR-1 uses a common binding interaction to recognize class I MHC molecules and the viral homolog UL18.Q33883093
Down-regulation of MHC class I antigen presentation by HCMV; lessons for tumor immunologyQ33943132
A complex between the MHC class I homologue encoded by human cytomegalovirus and beta 2 microglobulinQ34197436
Insertion and deletion mutagenesis of the human cytomegalovirus genomeQ34354191
Murine cytomegalovirus with a transposon insertional mutation at open reading frame m155 is deficient in growth and virulence in miceQ34437908
Constitutive and enhanced expression from the CMV major IE promoter in a defective adenovirus vectorQ35068584
Glycosyltransferases encoded by virusesQ35901720
Modulation of natural killer cell cytotoxicity in human cytomegalovirus infection: the role of endogenous class I major histocompatibility complex and a viral class I homologQ36400815
Cytomegalovirus encodes a potent alpha chemokineQ36436978
Human cytomegalovirus harbors its own unique IL-10 homolog (cmvIL-10)Q37113833
Identification of proteins in human cytomegalovirus (HCMV) particles: the HCMV proteomeQ37568012
Analysis of the protein-coding content of the sequence of human cytomegalovirus strain AD169.Q37879797
Multiple independent loci within the human cytomegalovirus unique short region down-regulate expression of major histocompatibility complex class I heavy chainsQ39871175
Human cytomegalovirus IE1 and IE2 proteins block apoptosisQ39872769
An IgG-Fc receptor induced in cytomegalovirus-infected human fibroblastsQ39979714
Construction and characterization of a human cytomegalovirus mutant with the UL18 (class I homolog) gene deletedQ40060908
Genetic variability of the major histocompatibility complex class I homologue encoded by human cytomegalovirus leads to differential binding to the inhibitory receptor ILT2.Q40463753
Specific recognition of the viral protein UL18 by CD85j/LIR-1/ILT2 on CD8+ T cells mediates the non-MHC-restricted lysis of human cytomegalovirus-infected cellsQ40564304
Human cytomegalovirus UL18 alleviated human NK-mediated swine endothelial cell lysis.Q40580126
Differential effects of US2, US6 and US11 human cytomegalovirus proteins on HLA class Ia and HLA-E expression: impact on target susceptibility to NK cell subsetsQ40630666
Two novel spliced genes in human cytomegalovirusQ40655845
Direct recognition of cytomegalovirus by activating and inhibitory NK cell receptorsQ40738490
Differential expression of leukocyte receptor complex-encoded Ig-like receptors correlates with the transition from effector to memory CTL.Q40822163
Surface expression of HLA-E, an inhibitor of natural killer cells, enhanced by human cytomegalovirus gpUL40.Q40900792
Cutting edge: a novel viral TNF receptor superfamily member in virulent strains of human cytomegalovirus.Q40950579
The class I MHC homologue of human cytomegalovirus inhibits attack by natural killer cellsQ41116878
Inhibition of natural killer cells by a cytomegalovirus MHC class I homologue in vivo.Q42652565
The MHC class I homolog encoded by human cytomegalovirus binds endogenous peptidesQ45992897
Genetic content of wild-type human cytomegalovirusQ47709383
Human cytomegalovirus encodes a glycoprotein homologous to MHC class-I antigensQ48330648
Expression of KIR2DL1 on the entire NK cell population: a possible novel immunodeficiency syndrome.Q51026937
The MHC class I homolog of human cytomegalovirus is resistant to down-regulation mediated by the unique short region protein (US)2, US3, US6, and US11 gene products.Q53672251
Human cytomegalovirus (HCMV)-infected endothelial cells and macrophages are less susceptible to natural killer lysis independent of the downregulation of classical HLA class I molecules or expression of the HCMV class I homologue, UL18.Q53976561
Severe herpesvirus infections in an adolescent without natural killer cellsQ55984308
LIR-1 expression on lymphocytes, and cytomegalovirus disease in lung-transplant recipientsQ58321054
A simple technique for the rescue of early region I mutations into infectious human adenovirus type 5Q64379529
P433issuePt 11
P407language of work or nameEnglishQ1860
P921main subjectglycosylationQ898365
P304page(s)2999-3008
P577publication date2005-11-01
P1433published inJournal of General VirologyQ6295245
P1476titleCharacterization of a highly glycosylated form of the human cytomegalovirus HLA class I homologue gpUL18
P478volume86

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cites work (P2860)
Q39706964Adenovirus vector delivery stimulates natural killer cell recognition.
Q34269060Depletion of cellular pre-replication complex factors results in increased human cytomegalovirus DNA replication
Q52341713Global Aspects of Viral Glycosylation Enveloped viruses/herpesvirus/mass spectrometry/mucin type O-glycosylation/viral glycans.
Q35828380Human cytomegalovirus UL40 signal peptide regulates cell surface expression of the NK cell ligands HLA-E and gpUL18
Q36221684Human cytomegalovirus latency alters the cellular secretome, inducing cluster of differentiation (CD)4+ T-cell migration and suppression of effector function
Q33744384Modulation of natural killer cells by human cytomegalovirus
Q34090187Reconstruction of the complete human cytomegalovirus genome in a BAC reveals RL13 to be a potent inhibitor of replication.
Q33744070The human cytomegalovirus MHC class I homolog UL18 inhibits LIR-1+ but activates LIR-1- NK cells.
Q39792603The myeloid transcription factor GATA-2 regulates the viral UL144 gene during human cytomegalovirus latency in an isolate-specific manner
Q35671392Traditional biochemical assays for studying toll-like receptor 9.
Q33553680Two novel human cytomegalovirus NK cell evasion functions target MICA for lysosomal degradation

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