Stimulation of bone healing by sustained bone morphogenetic protein 2 (BMP-2) delivery

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Stimulation of bone healing by sustained bone morphogenetic protein 2 (BMP-2) delivery is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3390/IJMS15058539
P932PMC publication ID4057747
P698PubMed publication ID24830556
P5875ResearchGate publication ID262381651

P50authorBritt WildemannQ47175956
P2093author name stringGerhard Schmidmaier
Catrin Strobel
Susann Minkwitz
Mirja Faßbender
P2860cites workEndocultivation: the influence of delayed vs. simultaneous application of BMP-2 onto individually formed hydroxyapatite matrices for heterotopic bone inductionQ84263446
The effect of a slow mode of BMP-2 delivery on the inflammatory response provoked by bone-defect-filling polymeric scaffoldsQ84575628
Distinct and overlapping patterns of localization of bone morphogenetic protein (BMP) family members and a BMP type II receptor during fracture healing in ratsQ28567049
Biodegradable poly(D,L-lactide) coating of implants for continuous release of growth factorsQ31926776
Characterization of a rat osteotomy model with impaired healingQ33374632
Molecular mechanisms controlling bone formation during fracture healing and distraction osteogenesisQ35029178
Emerging role of bone morphogenetic proteins in angiogenesisQ37510292
Growth factors: beyond bone morphogenetic proteinsQ37782221
Fracture healing under healthy and inflammatory conditionsQ37980336
Polycaprolactone scaffold and reduced rhBMP-7 dose for the regeneration of critical-sized defects in sheep tibiae.Q39342901
Sequential release kinetics of two (gentamicin and BMP-2) or three (gentamicin, IGF-I and BMP-2) substances from a one-component polymeric coating on implantsQ39504972
Altered relative expression of BMPs and BMP inhibitors in cartilaginous areas of human fractures progressing towards nonunionQ42044773
The kinetic and biological activity of different loaded rhBMP-2 calcium phosphate cement implants in ratsQ42642549
Local application of zoledronic acid incorporated in a poly(D,L-lactide)-coated implant accelerates fracture healing in ratsQ43677840
Bone regeneration using a bone morphogenetic protein-2 saturated slow-release gelatin hydrogel sheet: evaluation in a canine orbital floor fracture modelQ44798665
Delayed administration of adenoviral BMP-2 vector improves the formation of bone in osseous defectsQ45867586
Influence of short-term adenoviral vector and prolonged lentiviral vector mediated bone morphogenetic protein-2 expression on the quality of bone repair in a rat femoral defect modelQ45875445
Global gene profiling reveals a downregulation of BMP gene expression in experimental atrophic nonunions compared to standard healing fracturesQ46277132
Immunolocalization of BMPs, BMP antagonists, receptors, and effectors during fracture repair.Q46582416
Recombinant human bone morphogenetic protein-2 for treatment of open tibial fractures: a prospective, controlled, randomized study of four hundred and fifty patientsQ46954545
IGF-I and TGF-beta 1 incorporated in a poly(D,L-lactide) implant coating maintain their activity over long-term storage-cell culture studies on primary human osteoblast-like cellsQ47953188
Deproteinized bovine bone functionalized with the slow delivery of BMP-2 for the repair of critical-sized bone defects in sheep.Q50940548
Local gentamicin application does not interfere with bone healing in a rat model.Q51247256
Short term in vivo biocompatibility testing of biodegradable poly(D,L-lactide)--growth factor coating for orthopaedic implants.Q51559907
BMP2 activity, although dispensable for bone formation, is required for the initiation of fracture healing.Q52002102
Application of BMP-7 to tibial non-unions: a 3-year multicenter experience.Q52850799
Local BMP-2 application can rescue the delayed osteotomy healing in a rat model.Q52900016
Insight into the molecular pathophysiology of delayed bone healing in a sheep model.Q52909202
The effect of recombinant human osteogenic protein-1 on healing of large segmental bone defectsQ72501474
Differential temporal expression of members of the transforming growth factor beta superfamily during murine fracture healingQ77716685
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectmorphogenesisQ815547
P304page(s)8539-8552
P577publication date2014-05-14
P1433published inInternational Journal of Molecular SciencesQ3153277
P1476titleStimulation of bone healing by sustained bone morphogenetic protein 2 (BMP-2) delivery
P478volume15

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cites work (P2860)
Q52597057A canine in vitro model for evaluation of marrow-derived mesenchymal stromal cell-based bone scaffolds.
Q36448443Allogeneic Platelet Releasate Preparations Derived via a Novel Rapid Thrombin Activation Process Promote Rapid Growth and Increased BMP-2 and BMP-4 Expression in Human Adipose-Derived Stem Cells
Q36347762Bisphosphonate-adsorbed ceramic nanoparticles increase bone formation in an injectable carrier for bone tissue engineering.
Q37286934Bone morphogenetic protein-2 provokes interleukin-18-induced human intervertebral disc degeneration
Q47260898Continuous stimulation with differentiation factors is necessary to enhance osteogenic differentiation of human mesenchymal stem cells in-vitro
Q92446575Exploratory Full-Field Strain Analysis of Regenerated Bone Tissue from Osteoinductive Biomaterials
Q31052456Investigational drugs for fracture healing: preclinical & clinical data.
Q38844138Osteogenic differentiation and proliferation of bone marrow-derived mesenchymal stromal cells on PDLLA + BMP-2-coated titanium alloy surfaces
Q38865480Role of Vascular Endothelial Growth Factor and Transforming Growth Factor-β2 in Rat Bone Tissue after Bone Fracture and Placement of Titanium Implants with Bioactive Bioresorbable Coatings
Q38772538Synergistic Effects of Vascular Endothelial Growth Factor on Bone Morphogenetic Proteins Induced Bone Formation In Vivo: Influencing Factors and Future Research Directions.